메뉴 건너뛰기




Volumn 682, Issue , 2011, Pages 103-114

Fluorochrome-Labeled Inhibitors of Caspases: Convenient In Vitro and In Vivo Markers of Apoptotic Cells for Cytometric Analysis

Author keywords

Annexin V binding; Apoptosis; Caspases; Cell death; FLICA; Flow cytometry; Laser scanning cytometry; Mitochondrial potential

Indexed keywords

BIOLOGICAL MARKER; CASPASE; FLUORESCENT DYE; PROTEINASE INHIBITOR;

EID: 79952198769     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60327-409-8_9     Document Type: Chapter
Times cited : (39)

References (26)
  • 3
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw, W.C., Martins, L.M., and Kaufmann, S.H. (1999) Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem., 68, 383–424.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 4
    • 0032785021 scopus 로고    scopus 로고
    • Caspase structure, proteolytic substrates and function during apoptotic cell death
    • Nicholson, D.W. (1999) Caspase structure, proteolytic substrates and function during apoptotic cell death. Cell Death Differ., 6, 1028–1042.
    • (1999) Cell Death Differ , vol.6 , pp. 1028-1042
    • Nicholson, D.W.1
  • 5
    • 0034608386 scopus 로고    scopus 로고
    • Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates
    • Komoriya, A., Packard, B.Z., Brown, M.J., Wu, M.L., and Henkart, P.A. (2000) Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates. J. Exp. Med., 191, 1819–1828.
    • (2000) J. Exp. Med. , vol.191 , pp. 1819-1828
    • Komoriya, A.1    Packard, B.Z.2    Brown, M.J.3    Wu, M.L.4    Henkart, P.A.5
  • 7
    • 0242526431 scopus 로고    scopus 로고
    • Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells. A caution in data interpretation
    • Pozarowski, P., Huang, X., Halicka D.H., Lee, B., Johnson, G., and Darzynkiewicz, Z. (2003) Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells. A caution in data interpretation. Cytometry A, 55A, 50–60.
    • (2003) Cytometry A , vol.55A , pp. 50-60
    • Pozarowski, P.1    Huang, X.2    Halicka, D.H.3    Lee, B.4    Johnson, G.5    Darzynkiewicz, Z.6
  • 8
    • 1942534150 scopus 로고    scopus 로고
    • Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by DNA crosslinking agent cisplatin
    • Huang, X., Okafuji, M., Traganos, F., Luther, E., Holden, E., and Darzynkiewicz, Z. (2004) Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by DNA crosslinking agent cisplatin. Cytometry A, 58A, 99–110.
    • (2004) Cytometry A , vol.58A , pp. 99-110
    • Huang, X.1    Okafuji, M.2    Traganos, F.3    Luther, E.4    Holden, E.5    Darzynkiewicz, Z.6
  • 9
    • 0034712259 scopus 로고    scopus 로고
    • Cleavage of poly(ADP-ribose) polymerase measured in situ in individual cells: Relationship to DNA fragmentation and cell cycle position during apoptosis
    • Li, X., and Darzynkiewicz, Z. (2000) Cleavage of poly(ADP-ribose) polymerase measured in situ in individual cells: relationship to DNA fragmentation and cell cycle position during apoptosis. Exp. Cell Res., 255, 125–132.
    • (2000) Exp. Cell Res. , vol.255 , pp. 125-132
    • Li, X.1    Darzynkiewicz, Z.2
  • 10
    • 0034714009 scopus 로고    scopus 로고
    • Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): Correlation with DNA fragmentation
    • Bedner, E., Smolewski, P., Amstad, P., and Darzynkiewicz, Z. (2000) Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation. Exp. Cell Res., 260, 308–313.
    • (2000) Exp. Cell Res. , vol.260 , pp. 308-313
    • Bedner, E.1    Smolewski, P.2    Amstad, P.3    Darzynkiewicz, Z.4
  • 11
    • 0035340652 scopus 로고    scopus 로고
    • Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry
    • Smolewski, P., Bedner, E., Du, L., Hsieh, T.-C., Wu, J.M., Phelps, D.J., and Darzynkiewicz, Z. (2001) Detection of caspases activation by fluorochrome-labeled inhibitors: multiparameter analysis by laser scanning cytometry. Cytometry, 44, 73–82.
    • (2001) Cytometry , vol.44 , pp. 73-82
    • Smolewski, P.1    Bedner, E.2    Du, L.3    Hsieh, T.-C.4    Wu, J.M.5    Phelps, D.J.6    Darzynkiewicz, Z.7
  • 12
    • 0001542603 scopus 로고
    • Specific proteases of mast cells
    • Darzynkiewicz, Z., and Barnard, E.A. (1966) Specific proteases of mast cells. Nature, 212, 1198–1203.
    • (1966) Nature , vol.212 , pp. 1198-1203
    • Darzynkiewicz, Z.1    Barnard, E.A.2
  • 13
    • 0036490576 scopus 로고    scopus 로고
    • Kinetics of HL-60 cell entry to apoptosis during treatment with TNF-a or camptothecin assayed by the stathmo-apoptosis method
    • Smolewski, P., Grabarek, J., Lee, B.W., Johnson, G.L., and Darzynkiewicz, Z. (2002) Kinetics of HL-60 cell entry to apoptosis during treatment with TNF-a or camptothecin assayed by the stathmo-apoptosis method. Cytometry, 47, 143–149.
    • (2002) Cytometry , vol.47 , pp. 143-149
    • Smolewski, P.1    Grabarek, J.2    Lee, B.W.3    Johnson, G.L.4    Darzynkiewicz, Z.5
  • 14
    • 0035489015 scopus 로고    scopus 로고
    • Stathmo-apoptosis: Arresting apoptosis by fluorochrome-labeled inhibitor of caspases
    • Smolewski, P., Grabarek, J., Phelps, D.J., and Darzynkiewicz, Z. (2001) Stathmo-apoptosis: arresting apoptosis by fluorochrome-labeled inhibitor of caspases. Int. J. Oncol., 19, 657–663.
    • (2001) Int. J. Oncol. , vol.19 , pp. 657-663
    • Smolewski, P.1    Grabarek, J.2    Phelps, D.J.3    Darzynkiewicz, Z.4
  • 16
    • 34547650722 scopus 로고    scopus 로고
    • All that glitters is not gold: All that binds FLICA is not caspase. A caution in data interpretation – and new opportunities
    • Darzynkiewicz, Z., and Pozarowski, P. (2007) All that glitters is not gold: all that binds FLICA is not caspase. A caution in data interpretation – and new opportunities. Cytometry A, 71A, 536–537.
    • (2007) Cytometry A , vol.71A , pp. 536-537
    • Darzynkiewicz, Z.1    Pozarowski, P.2
  • 18
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphati-dylderine expression of B cells undergoing apoptosis
    • Koopman, G., Reutelingsperger, C.P.M., Kuijten, G.A.M., Kechnen, R.M.J., Pals, S.T., and van Oers, M.H.H. (1994) Annexin V for flow cytometric detection of phosphati-dylderine expression of B cells undergoing apoptosis. Blood, 84, 1415–1420.
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.M.2    Kuijten, G.A.M.3    Kechnen, R.M.J.4    Pals, S.T.5    van Oers, M.H.H.6
  • 19
    • 33747421048 scopus 로고    scopus 로고
    • Laser scanning cytometry. Principles and applications
    • Pozarowski, P., Holden, E., and Darzynkiewicz, Z. (2005) Laser scanning cytometry. Principles and applications. Methods Mol. Biol., 319, 165–192.
    • (2005) Methods Mol. Biol. , vol.319 , pp. 165-192
    • Pozarowski, P.1    Holden, E.2    Darzynkiewicz, Z.3
  • 20
    • 0035234207 scopus 로고    scopus 로고
    • Difficulties and pitfalls in analysis of apoptosis
    • Darzynkiewicz, Z., Bedner, E., and Traganos, F. (2001) Difficulties and pitfalls in analysis of apoptosis. Methods Cell Biol., 63, 527–559.
    • (2001) Methods Cell Biol , vol.63 , pp. 527-559
    • Darzynkiewicz, Z.1    Bedner, E.2    Traganos, F.3
  • 21
    • 44949234812 scopus 로고    scopus 로고
    • Multiparameter detection of apoptosis using red-excitable SYTO probes
    • Wlodkowic, D., Skommer, J., Hillier, C., and Darzynkiewicz, Z. (2008) Multiparameter detection of apoptosis using red-excitable SYTO probes. Cytometry A, 73A, 563–569.
    • (2008) Cytometry A , vol.73A , pp. 563-569
    • Wlodkowic, D.1    Skommer, J.2    Hillier, C.3    Darzynkiewicz, Z.4
  • 22
    • 37549018148 scopus 로고    scopus 로고
    • Use of fluorescently labeled poly-cas-pase inhibitor for in vivo detection of apoptosis related to vascular-targeting agent arsenic trioxide for cancer therapy
    • Griffin R.J., Williams, B.W., Bischof, J.C., Olin, M., Johnson, G.L., and Lee, B.W. (2007) Use of fluorescently labeled poly-cas-pase inhibitor for in vivo detection of apoptosis related to vascular-targeting agent arsenic trioxide for cancer therapy. Technol. Cancer Res. Treat., 6, 651–654.
    • (2007) Technol. Cancer Res. Treat. , vol.6 , pp. 651-654
    • Griffin, R.J.1    Williams, B.W.2    Bischof, J.C.3    Olin, M.4    Johnson, G.L.5    Lee, B.W.6
  • 23
    • 37849005392 scopus 로고    scopus 로고
    • In vitro and in vivo apoptosis detection using membrane permeant fluorescent-labeled inhibitors of caspases
    • Lee, B.W., Olin, M.R., Johnson, G.L., and Griffin, R.J. (2008) In vitro and in vivo apoptosis detection using membrane permeant fluorescent-labeled inhibitors of caspases. Methods Mol. Biol., 414, 109–135.
    • (2008) Methods Mol. Biol. , vol.414 , pp. 109-135
    • Lee, B.W.1    Olin, M.R.2    Johnson, G.L.3    Griffin, R.J.4
  • 25
    • 48049090288 scopus 로고    scopus 로고
    • Liver apoptosis following normothermic ischemia-reperfusion: In vivo evaluation of caspase activity by FLIVO assay in rats
    • Cursio, R., Colosetti, P., Auberger, P., and Gugenheim, J. (2008) Liver apoptosis following normothermic ischemia-reperfusion: in vivo evaluation of caspase activity by FLIVO assay in rats. Transplant. Proc., 40, 2038–2041.
    • (2008) Transplant. Proc. , vol.40 , pp. 2038-2041
    • Cursio, R.1    Colosetti, P.2    Auberger, P.3    Gugenheim, J.4
  • 26


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.