Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block

Organic Process Research and Development

Volumn 19, Issue 6, 2015, Pages 635-638

  Metzner, Richard ^a   Hummel, Werner ^b   Wetterich, Frank ^c   König, Burghard ^d   Gröger, Harald ^a  

^a BIELEFELD UNIVERSITY   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c Sandoz Pharma Ltd   (Switzerland)

^d Sandoz Industrial Products GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCATALYSTS; BIOSYNTHESIS; CATALYSIS; DRUG PRODUCTS;

ACTIVE PHARMACEUTICAL INGREDIENTS; BLOCKBUSTER DRUGS; BUILDING BLOCKES; HIGH SUBSTRATE CONCENTRATIONS; INDUSTRIAL PROCESSS; ORGANIC SYNTHESIS; PHARMACEUTICAL DRUGS; SPACE TIME YIELD;

ENZYMES;

EID: 84934968709     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/acs.oprd.5b00057     Document Type: Article

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