메뉴 건너뛰기




Volumn 25, Issue 4, 2015, Pages 595-602

Microrna-130b regulates scleroderma fi brosis by targeting peroxisome proliferator-activated receptor g

Author keywords

MiR 130b; PPAR ; Scleroderma; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA 1; COLLAGEN TYPE 1 ALPHA 2; FIBRONECTIN; HYDROXYPROLINE; LIPOFECTAMINE; MICRORNA; MICRORNA 130B; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; MIRN130 MICRORNA, MOUSE; RNA;

EID: 84934944846     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.3109/14397595.2014.1001311     Document Type: Article
Times cited : (27)

References (34)
  • 1
    • 84655175061 scopus 로고    scopus 로고
    • Understanding fi brosis in systemic sclerosis: Shifting paradigms, emerging opportunities
    • Bhattacharyya S, Wei J, Varga J. Understanding fi brosis in systemic sclerosis: shifting paradigms, emerging opportunities. Nat Rev Rheumatol. 2012;8(1):42–54.
    • (2012) Nat Rev Rheumatol , vol.8 , Issue.1 , pp. 42-54
    • Bhattacharyya, S.1    Wei, J.2    Varga, J.3
  • 2
    • 67650480995 scopus 로고    scopus 로고
    • Transforming growth factor beta as a therapeutic target in systemic sclerosis
    • Varga J, Pasche B. Transforming growth factor beta as a therapeutic target in systemic sclerosis. Nat Rev Rheumatol. 2009;5(4):200–6.
    • (2009) Nat Rev Rheumatol , vol.5 , Issue.4 , pp. 200-206
    • Varga, J.1    Pasche, B.2
  • 3
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human disease
    • Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor beta in human disease. N Engl J Med. 2000;342(18):1350–8.
    • (2000) N Engl J Med , vol.342 , Issue.18 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 4
    • 77958025377 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma: Innate protection from excessive fi brogenesis and potential therapeutic target in systemic sclerosis
    • Wei J, Bhattacharyya S, Varga J. Peroxisome proliferator-activated receptor gamma: innate protection from excessive fi brogenesis and potential therapeutic target in systemic sclerosis. Curr Opin Rheumatol. 2010;22(6):671–6.
    • (2010) Curr Opin Rheumatol , vol.22 , Issue.6 , pp. 671-676
    • Wei, J.1    Bhattacharyya, S.2    Varga, J.3
  • 5
    • 84863946574 scopus 로고    scopus 로고
    • Regulation of matrix remodeling by peroxisome proliferator-activated receptor-gamma: A novel link between metabolism and fi brogenesis
    • Wei J, Bhattacharyya S, Jain M, Varga J. Regulation of matrix remodeling by peroxisome proliferator-activated receptor-gamma: a novel link between metabolism and fi brogenesis. Open Rheumatol J. 2012;6:103–15.
    • (2012) Open Rheumatol J , vol.6 , pp. 103-115
    • Wei, J.1    Bhattacharyya, S.2    Jain, M.3    Varga, J.4
  • 6
    • 1842733168 scopus 로고    scopus 로고
    • Disruption of transforming growth factor beta signaling and profi brotic responses in normal skin fi broblasts by peroxisome proliferator-activated receptor gamma
    • Ghosh AK, Bhattacharyya S, Lakos G, Chen SJ, Mori Y, Varga J. Disruption of transforming growth factor beta signaling and profi brotic responses in normal skin fi broblasts by peroxisome proliferator-activated receptor gamma. Arthritis Rheum. 2004;50(4):1305–18.
    • (2004) Arthritis Rheum , vol.50 , Issue.4 , pp. 1305-1318
    • Ghosh, A.K.1    Bhattacharyya, S.2    Lakos, G.3    Chen, S.J.4    Mori, Y.5    Varga, J.6
  • 7
    • 84867762854 scopus 로고    scopus 로고
    • Organ fi brosis inhibited by blocking transforming growth factor-beta signaling via peroxisome proliferator-activated receptor gamma agonists
    • Deng YL, Xiong XZ, Cheng NS. Organ fi brosis inhibited by blocking transforming growth factor-beta signaling via peroxisome proliferator-activated receptor gamma agonists. Hepatobiliary Pancreat Dis Int. 2012;11(5):467–78.
    • (2012) Hepatobiliary Pancreat Dis Int , vol.11 , Issue.5 , pp. 467-478
    • Deng, Y.L.1    Xiong, X.Z.2    Cheng, N.S.3
  • 8
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • Stefani G, Slack FJ. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol. 2008;9(3):219–30.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.3 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 9
    • 34547960488 scopus 로고    scopus 로고
    • Cohen SM. MicroRNA functions
    • Bushati N, Cohen SM. microRNA functions. Annu Rev Cell Dev Biol. 2007;23:175–205.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 175-205
    • Bushati, N.1
  • 10
    • 77951219188 scopus 로고    scopus 로고
    • MicroRNAs and the regulation of fibrosis
    • Jiang X, Tsitsiou E, Herrick SE, Lindsay MA. MicroRNAs and the regulation of fibrosis. FEBS J. 2010;277(9):2015–21.
    • (2010) FEBS J , vol.277 , Issue.9 , pp. 2015-2021
    • Jiang, X.1    Tsitsiou, E.2    Herrick, S.E.3    Lindsay, M.A.4
  • 11
    • 84857063439 scopus 로고    scopus 로고
    • MicroRNA array analysis of microRNAs related to systemic scleroderma
    • Li H, Yang R, Fan X, Gu T, Zhao Z, Chang D, Wang W. MicroRNA array analysis of microRNAs related to systemic scleroderma. Rheumatol Int. 2012;32(2):307–13.
    • (2012) Rheumatol Int , vol.32 , Issue.2 , pp. 307-313
    • Li, H.1    Yang, R.2    Fan, X.3    Gu, T.4    Zhao, Z.5    Chang, D.6    Wang, W.7
  • 12
    • 84862829123 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in limited cutaneous scleroderma and diff use cutaneous scleroderma
    • Zhu H, Li Y, Qu S, Luo H, Zhou Y, Wang Y, et al. MicroRNA expression abnormalities in limited cutaneous scleroderma and diff use cutaneous scleroderma. J Clin Immunol. 2012;32(3):514–22.
    • (2012) J Clin Immunol , vol.32 , Issue.3 , pp. 514-522
    • Zhu, H.1    Li, Y.2    Qu, S.3    Luo, H.4    Zhou, Y.5    Wang, Y.6
  • 13
    • 84885100164 scopus 로고    scopus 로고
    • MicroRNAs: Their involvement in fi brosis pathogenesis and use as diagnostic biomarkers in scleroderma
    • Zhu H, Luo H, Zuo X. MicroRNAs: their involvement in fi brosis pathogenesis and use as diagnostic biomarkers in scleroderma. Exp Mol Med. 2013;45:e41.
    • (2013) Exp Mol Med , vol.45
    • Zhu, H.1    Luo, H.2    Zuo, X.3
  • 14
    • 0018887574 scopus 로고
    • Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee
    • Preliminary criteria for the classifi cation of systemic sclerosis (scleroderma)
    • Preliminary criteria for the classifi cation of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum. 1980;23(5):581–90.
    • (1980) Arthritis Rheum , vol.23 , Issue.5 , pp. 581-590
  • 16
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008;3(6):1101–8.
    • (2008) Nat Protoc , vol.3 , Issue.6 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 17
    • 58249120518 scopus 로고    scopus 로고
    • Treatment with imatinib prevents fi brosis in diff erent preclinical models of systemic sclerosis and induces regression of established fibrosis
    • Akhmetshina A, Venalis P, Dees C, Busch N, Zwerina J, Schett G, et al. Treatment with imatinib prevents fi brosis in diff erent preclinical models of systemic sclerosis and induces regression of established fibrosis. Arthritis Rheum. 2009;60(1):219–24.
    • (2009) Arthritis Rheum , vol.60 , Issue.1 , pp. 219-224
    • Akhmetshina, A.1    Venalis, P.2    Dees, C.3    Busch, N.4    Zwerina, J.5    Schett, G.6
  • 18
    • 33846209989 scopus 로고    scopus 로고
    • Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
    • Distler JH, Jungel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, et al. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum. 2007;56(1):311–22.
    • (2007) Arthritis Rheum , vol.56 , Issue.1 , pp. 311-322
    • Distler, J.H.1    Jungel, A.2    Huber, L.C.3    Schulze-Horsel, U.4    Zwerina, J.5    Gay, R.E.6
  • 19
    • 77950433107 scopus 로고    scopus 로고
    • Rosiglitazone alleviates the persistent fi brotic phenotype of lesional skin scleroderma fibroblasts
    • Shi-wen X, Eastwood M, Stratton RJ, Denton CP, Leask A, Abraham DJ. Rosiglitazone alleviates the persistent fi brotic phenotype of lesional skin scleroderma fibroblasts. Rheumatology (Oxford). 2010;49(2):259–63.
    • (2010) Rheumatology (Oxford) , vol.49 , Issue.2 , pp. 259-263
    • Shi-Wen, X.1    Eastwood, M.2    Stratton, R.J.3    Denton, C.P.4    Leask, A.5    Abraham, D.J.6
  • 20
    • 69449094871 scopus 로고    scopus 로고
    • Loss of peroxisome proliferator-activated receptor gamma in mouse fi broblasts results in increased susceptibility to bleomycin-induced skin fibrosis
    • Kapoor M, McCann M, Liu S, Huh K, Denton CP, Abraham DJ, Leask A. Loss of peroxisome proliferator-activated receptor gamma in mouse fi broblasts results in increased susceptibility to bleomycin-induced skin fibrosis. Arthritis Rheum. 2009;60(9):2822–9.
    • (2009) Arthritis Rheum , vol.60 , Issue.9 , pp. 2822-2829
    • Kapoor, M.1    Mccann, M.2    Liu, S.3    Huh, K.4    Denton, C.P.5    Abraham, D.J.6    Leask, A.7
  • 21
    • 84890129748 scopus 로고    scopus 로고
    • Circulating miR-130b mediates metabolic crosstalk between fat and muscle in overweight/obesity
    • Wang YC, Li Y, Wang XY, Zhang D, Zhang H, Wu Q, et al. Circulating miR-130b mediates metabolic crosstalk between fat and muscle in overweight/obesity. Diabetologia. 2013;56(10):2275–85.
    • (2013) Diabetologia , vol.56 , Issue.10 , pp. 2275-2285
    • Wang, Y.C.1    Li, Y.2    Wang, X.Y.3    Zhang, D.4    Zhang, H.5    Wu, Q.6
  • 22
    • 79251544878 scopus 로고    scopus 로고
    • Martindale JL, et al. MiR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression
    • Lee EK, Lee MJ, Abdelmohsen K, Kim W, Kim MM, Srikantan S, Martindale JL, et al. miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol. 2011;31(4):626–38.
    • (2011) Mol Cell Biol , vol.31 , Issue.4 , pp. 626-638
    • Lee, E.K.1    Lee, M.J.2    Abdelmohsen, K.3    Kim, W.4    Kim, M.M.5    Srikantan, S.6
  • 23
    • 84878018555 scopus 로고    scopus 로고
    • MicroRNA-130b and microRNA-374b mediate the eff ect of maternal dietary protein on off spring lipid metabolism in Meishan pigs
    • Pan S, Zheng Y, Zhao R, Yang X. MicroRNA-130b and microRNA-374b mediate the eff ect of maternal dietary protein on off spring lipid metabolism in Meishan pigs. Br J Nutr. 2013;109(10):1731–8.
    • (2013) Br J Nutr , vol.109 , Issue.10 , pp. 1731-1738
    • Pan, S.1    Zheng, Y.2    Zhao, R.3    Yang, X.4
  • 24
    • 84867370115 scopus 로고    scopus 로고
    • PPARs in liver diseases and cancer: Epigenetic regulation by MicroRNAs
    • Peyrou M, Ramadori P, Bourgoin L, Foti M. PPARs in liver diseases and cancer: epigenetic regulation by MicroRNAs. PPAR Res. 2012;2012:757803.
    • (2012) PPAR Res , vol.2012 , pp. 757803
    • Peyrou, M.1    Ramadori, P.2    Bourgoin, L.3    Foti, M.4
  • 26
    • 84880316996 scopus 로고    scopus 로고
    • MicroRNA-21 in scleroderma fi brosis and its function in TGF-beta-regulated fi brosis-related genes expression
    • Zhu H, Luo H, Li Y, Zhou Y, Jiang Y, Chai J, et al. MicroRNA-21 in scleroderma fi brosis and its function in TGF-beta-regulated fi brosis-related genes expression. J Clin Immunol. 2013;33(6):1100–9.
    • (2013) J Clin Immunol , vol.33 , Issue.6 , pp. 1100-1109
    • Zhu, H.1    Luo, H.2    Li, Y.3    Zhou, Y.4    Jiang, Y.5    Chai, J.6
  • 28
    • 70349254621 scopus 로고    scopus 로고
    • The antifi brogenic potential of PPARgamma ligands in pulmonary fibrosis
    • Sime PJ. The antifi brogenic potential of PPARgamma ligands in pulmonary fibrosis. J Investig Med. 2008;56(2):534–8.
    • (2008) J Investig Med , vol.56 , Issue.2 , pp. 534-538
    • Sime, P.J.1
  • 30
    • 47349119166 scopus 로고    scopus 로고
    • A novel mechanism of PPARgamma regulation of TGFbeta1: Implication in cancer biology
    • Lee CH, Kim HD, Shin SM, Kim SG. A novel mechanism of PPARgamma regulation of TGFbeta1: implication in cancer biology. PPAR Res. 2008;2008:762398.
    • (2008) PPAR Res , vol.2008 , pp. 762398
    • Lee, C.H.1    Kim, H.D.2    Shin, S.M.3    Kim, S.G.4
  • 31
    • 84871284466 scopus 로고    scopus 로고
    • Toll-like receptor 4 signaling augments transforming growth factor-beta responses: A novel mechanism for maintaining and amplifying fi brosis in scleroderma
    • Bhattacharyya S, Kelley K, Melichian DS, Tamaki Z, Fang F, Su Y, et al. Toll-like receptor 4 signaling augments transforming growth factor-beta responses: a novel mechanism for maintaining and amplifying fi brosis in scleroderma. Am J Pathol. 2013;182(1):192–205.
    • (2013) Am J Pathol , vol.182 , Issue.1 , pp. 192-205
    • Bhattacharyya, S.1    Kelley, K.2    Melichian, D.S.3    Tamaki, Z.4    Fang, F.5    Su, Y.6
  • 32
    • 26444471700 scopus 로고    scopus 로고
    • A SUMOylation-dependent pathway mediates transrepression of infl ammatory response genes by PPAR-gamma
    • Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, et al. A SUMOylation-dependent pathway mediates transrepression of infl ammatory response genes by PPAR-gamma. Nature. 2005;437(7059):759–763.
    • (2005) Nature , vol.437 , Issue.7059 , pp. 759-763
    • Pascual, G.1    Fong, A.L.2    Ogawa, S.3    Gamliel, A.4    Li, A.C.5    Perissi, V.6
  • 33
    • 84863923526 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fi brotic responses in mesenchymal cells
    • Wei J, Fang F, Lam AP, Sargent JL, Hamburg E, Hinchcliff ME, et al. Wnt/beta-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fi brotic responses in mesenchymal cells. Arthritis Rheum. 2012;64(8):2734–45.
    • (2012) Arthritis Rheum , vol.64 , Issue.8 , pp. 2734-2745
    • Wei, J.1    Fang, F.2    Lam, A.P.3    Sargent, J.L.4    Hamburg, E.5    Hinchcliff, M.E.6
  • 34
    • 77952584924 scopus 로고    scopus 로고
    • Targeting microRNAs with small molecules: From dream to reality
    • Zhang S, Chen L, Jung EJ, Calin GA. Targeting microRNAs with small molecules: from dream to reality. Clin Pharmacol Ther. 2010;87(6):754–8.
    • (2010) Clin Pharmacol Ther , vol.87 , Issue.6 , pp. 754-758
    • Zhang, S.1    Chen, L.2    Jung, E.J.3    Calin, G.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.