메뉴 건너뛰기




Volumn 10, Issue 5, 2015, Pages

Treatment with 4-methylpyrazole modulated stellate cells and natural killer cells and ameliorated liver fibrosis in mice

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLPYRAZOLE; ALCOHOL DEHYDROGENASE 3; ALPHA SMOOTH MUSCLE ACTIN; CARBON TETRACHLORIDE; COLLAGEN; COLLAGEN TYPE 1ALPHA1; GAMMA INTERFERON; OXIDOREDUCTASE; RETINOIC ACID; RETINOL; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; PYRAZOLE DERIVATIVE;

EID: 84934940225     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127946     Document Type: Article
Times cited : (18)

References (43)
  • 1
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
    • 18195085
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev. 2008;88:125-172. doi:10.1152/physrev. 00013.2007 PMID:18195085
    • (2008) Physiol Rev. , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 3
    • 34248179500 scopus 로고    scopus 로고
    • SiRNA-mediated knockdown of connective tissue growth factor prevents Nnitrosodimethylamineinduced hepatic fibrosis in rats
    • 17344905
    • George J, Tsutsumi M. siRNA-mediated knockdown of connective tissue growth factor prevents Nnitrosodimethylamineinduced hepatic fibrosis in rats. Gene Ther. 2007;14:790-803. PMID:17344905
    • (2007) Gene Ther. , vol.14 , pp. 790-803
    • George, J.1    Tsutsumi, M.2
  • 4
    • 84863042103 scopus 로고    scopus 로고
    • Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin alpha (V) beta (3) engagement and PI3K/pAkt/NFkappaB signaling
    • 21953216
    • Urtasun R, Lopategi A, George J, Leung TM, Lu Y, Wang X, et al. Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin alpha (V) beta (3) engagement and PI3K/pAkt/NFkappaB signaling. Hepatology. 2012;55:594-608. doi:10.1002/hep. 24701 PMID:21953216
    • (2012) Hepatology , vol.55 , pp. 594-608
    • Urtasun, R.1    Lopategi, A.2    George, J.3    Leung, T.M.4    Lu, Y.5    Wang, X.6
  • 5
    • 0035793126 scopus 로고    scopus 로고
    • Dimethylnitrosamine-induced liver injury in rats: The early deposition of collagen
    • 11164615
    • George J, Rao KR, Stern R, Chandrakasan G. Dimethylnitrosamine-induced liver injury in rats: the early deposition of collagen. Toxicology. 2001;156:129-138. PMID:11164615
    • (2001) Toxicology , vol.156 , pp. 129-138
    • George, J.1    Rao, K.R.2    Stern, R.3    Chandrakasan, G.4
  • 6
    • 0344413735 scopus 로고    scopus 로고
    • Expression of hyaluronic acid in N-nitrosodimethylamine induced hepatic fibrosis in rats
    • 14643895
    • George J, Tsutsumi M, Takase S. Expression of hyaluronic acid in N-nitrosodimethylamine induced hepatic fibrosis in rats. Int J Biochem Cell Biol. 2004;36:307-319. PMID:14643895
    • (2004) Int J Biochem Cell Biol. , vol.36 , pp. 307-319
    • George, J.1    Tsutsumi, M.2    Takase, S.3
  • 7
    • 80052707667 scopus 로고    scopus 로고
    • Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches
    • 21803030
    • Mormone E, George J, Nieto N. Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches. Chem Biol Interact. 2011;193:225-231. doi:10.1016/j.cbi.2011.07.001 PMID:21803030
    • (2011) Chem Biol Interact. , vol.193 , pp. 225-231
    • Mormone, E.1    George, J.2    Nieto, N.3
  • 8
    • 84880406477 scopus 로고    scopus 로고
    • Interaction of hepatic stellate cells with diverse types of immune cells: Foe or friend?
    • 23855303
    • Yi HS, Jeong WI. Interaction of hepatic stellate cells with diverse types of immune cells: foe or friend? J Gastroenterol Hepatol. 2013;28 Suppl 1:99-104. doi:10.1111/jgh.12017 PMID:23855303
    • (2013) J Gastroenterol Hepatol. , vol.28 , pp. 99-104
    • Yi, H.S.1    Jeong, W.I.2
  • 9
    • 79956222106 scopus 로고    scopus 로고
    • Hepatic stellate cells function as regulatory bystanders
    • 21460203
    • Ichikawa S, Mucida D, Tyznik AJ, Kronenberg M, Cheroutre H. Hepatic stellate cells function as regulatory bystanders. J Immunol. 2011;186:5549-5555. doi:10.4049/jimmunol. 1003917 PMID:21460203
    • (2011) J Immunol. , vol.186 , pp. 5549-5555
    • Ichikawa, S.1    Mucida, D.2    Tyznik, A.J.3    Kronenberg, M.4    Cheroutre, H.5
  • 10
    • 84863082047 scopus 로고    scopus 로고
    • Retinoic acids and hepatic stellate cells in liver disease
    • 22320921
    • Lee YS, Jeong WI. Retinoic acids and hepatic stellate cells in liver disease. J Gastroenterol Hepatol. 2012;27 Suppl 2:75-79. doi:10.1111/j.1440-1746.2011.07007.x PMID:22320921
    • (2012) J Gastroenterol Hepatol. , vol.27 , pp. 75-79
    • Lee, Y.S.1    Jeong, W.I.2
  • 11
    • 32044443617 scopus 로고    scopus 로고
    • Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners
    • 16472598
    • Radaeva S, Sun R, Jaruga B, Nguyen VT, Tian Z, Gao B. Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners. Gastroenterology. 2006;130:435-452. PMID:16472598
    • (2006) Gastroenterology , vol.130 , pp. 435-452
    • Radaeva, S.1    Sun, R.2    Jaruga, B.3    Nguyen, V.T.4    Tian, Z.5    Gao, B.6
  • 12
    • 35349017872 scopus 로고    scopus 로고
    • Retinoic acid signaling sensitizes hepatic stellate cells to NK cell killing via upregulation of NK cell activating ligand RAE1
    • 17673545
    • Radaeva S, Wang L, Radaev S, Jeong WI, Park O, Gao B. Retinoic acid signaling sensitizes hepatic stellate cells to NK cell killing via upregulation of NK cell activating ligand RAE1. Am J Physiol Gastrointest Liver Physiol. 2007;293:G809-816. PMID:17673545
    • (2007) Am J Physiol Gastrointest Liver Physiol. , vol.293 , pp. G809-G816
    • Radaeva, S.1    Wang, L.2    Radaev, S.3    Jeong, W.I.4    Park, O.5    Gao, B.6
  • 13
    • 84868203631 scopus 로고    scopus 로고
    • CD11b (+) Gr1 (+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice
    • 22544759
    • Suh YG, Kim JK, Byun JS, Yi HS, Lee YS, Eun HS, et al. CD11b (+) Gr1 (+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice. Hepatology. 2012;56:1902-1912. doi:10.1002/hep. 25817 PMID:22544759
    • (2012) Hepatology , vol.56 , pp. 1902-1912
    • Suh, Y.G.1    Kim, J.K.2    Byun, J.S.3    Yi, H.S.4    Lee, Y.S.5    Eun, H.S.6
  • 14
    • 84906498641 scopus 로고    scopus 로고
    • Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice
    • 24668648
    • Yi HS, Lee YS, Byun JS, Seo W, Jeong JM, Park O, et al. Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice. Hepatology. 2014;60:1044-1053. doi:10.1002/hep. 27137 PMID:24668648
    • (2014) Hepatology , vol.60 , pp. 1044-1053
    • Yi, H.S.1    Lee, Y.S.2    Byun, J.S.3    Seo, W.4    Jeong, J.M.5    Park, O.6
  • 17
    • 0033580449 scopus 로고    scopus 로고
    • Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group
    • 10080845
    • Brent J, McMartin K, Phillips S, Burkhart KK, Donovan JW, Wells M, et al. Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. N Engl J Med. 1999;340:832-838. PMID:10080845
    • (1999) N Engl J Med. , vol.340 , pp. 832-838
    • Brent, J.1    McMartin, K.2    Phillips, S.3    Burkhart, K.K.4    Donovan, J.W.5    Wells, M.6
  • 18
    • 0030979057 scopus 로고    scopus 로고
    • Antidotes for methanol and ethylene glycol poisoning
    • 9120880
    • Jacobsen D, McMartin KE. Antidotes for methanol and ethylene glycol poisoning. J Toxicol Clin Toxicol. 1997;35:127-143. PMID:9120880
    • (1997) J Toxicol Clin Toxicol. , vol.35 , pp. 127-143
    • Jacobsen, D.1    McMartin, K.E.2
  • 19
    • 0023854288 scopus 로고
    • Characterization and identification of a pyrazole-inducible form of cytochrome P-450
    • 3335529
    • Palakodety RB, Clejan LA, Krikun G, Feierman DE, Cederbaum AI. Characterization and identification of a pyrazole-inducible form of cytochrome P-450. J Biol Chem. 1988;263:878-884. PMID:3335529
    • (1988) J Biol Chem. , vol.263 , pp. 878-884
    • Palakodety, R.B.1    Clejan, L.A.2    Krikun, G.3    Feierman, D.E.4    Cederbaum, A.I.5
  • 20
    • 33845937603 scopus 로고    scopus 로고
    • Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration
    • 17126819
    • Lopez-Valencia V, Rangel P, Rodriguez S, Hernandez-Munoz R. Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. Biochem Pharmacol. 2007;73:586-596. PMID:17126819
    • (2007) Biochem Pharmacol. , vol.73 , pp. 586-596
    • Lopez-Valencia, V.1    Rangel, P.2    Rodriguez, S.3    Hernandez-Munoz, R.4
  • 22
    • 37349108815 scopus 로고    scopus 로고
    • Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis
    • 18166357
    • Jeong WI, Park O, Gao B. Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis. Gastroenterology. 2008;134:248-258. doi:10. 1053/j.gastro.2007.09.034 PMID:18166357
    • (2008) Gastroenterology , vol.134 , pp. 248-258
    • Jeong, W.I.1    Park, O.2    Gao, B.3
  • 23
    • 79953752559 scopus 로고    scopus 로고
    • Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice
    • 21480338
    • Jeong WI, Park O, Suh YG, Byun JS, Park SY, Choi E, et al. Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice. Hepatology. 2011;53:1342-1351. doi:10.1002/hep. 24190 PMID:21480338
    • (2011) Hepatology , vol.53 , pp. 1342-1351
    • Jeong, W.I.1    Park, O.2    Suh, Y.G.3    Byun, J.S.4    Park, S.Y.5    Choi, E.6
  • 24
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • 11607032
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 2001;413:732-738. PMID:11607032
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 25
    • 46949097299 scopus 로고    scopus 로고
    • Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiationassociated gene 5
    • 18591409
    • Kato H, Takeuchi O, Mikamo-Satoh E, Hirai R, Kawai T, Matsushita K, et al. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiationassociated gene 5. J Exp Med. 2008;205:1601-1610. doi:10.1084/jem.20080091 PMID:18591409
    • (2008) J Exp Med. , vol.205 , pp. 1601-1610
    • Kato, H.1    Takeuchi, O.2    Mikamo-Satoh, E.3    Hirai, R.4    Kawai, T.5    Matsushita, K.6
  • 27
    • 80051551271 scopus 로고    scopus 로고
    • Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis
    • 21278145
    • Kluwe J, Wongsiriroj N, Troeger JS, Gwak GY, Dapito DH, Pradere JP, et al. Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis. Gut. 2011;60:1260-1268. doi:10.1136/gut.2010.209551 PMID:21278145
    • (2011) Gut , vol.60 , pp. 1260-1268
    • Kluwe, J.1    Wongsiriroj, N.2    Troeger, J.S.3    Gwak, G.Y.4    Dapito, D.H.5    Pradere, J.P.6
  • 28
    • 0030755313 scopus 로고    scopus 로고
    • Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells
    • 9328313
    • Okuno M, Moriwaki H, Imai S, Muto Y, Kawada N, Suzuki Y, et al. Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells. Hepatology. 1997;26:913-921. PMID:9328313
    • (1997) Hepatology , vol.26 , pp. 913-921
    • Okuno, M.1    Moriwaki, H.2    Imai, S.3    Muto, Y.4    Kawada, N.5    Suzuki, Y.6
  • 29
    • 51649131465 scopus 로고    scopus 로고
    • All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production
    • 18397230
    • Hisamori S, Tabata C, Kadokawa Y, Okoshi K, Tabata R, Mori A, et al. All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production. Liver Int. 2008;28:1217-1225. doi:10.1111/j.1478-3231.2008.01745.x PMID:18397230
    • (2008) Liver Int. , vol.28 , pp. 1217-1225
    • Hisamori, S.1    Tabata, C.2    Kadokawa, Y.3    Okoshi, K.4    Tabata, R.5    Mori, A.6
  • 30
    • 79961171627 scopus 로고    scopus 로고
    • Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis
    • 21290135
    • Murakami K, Kaji T, Shimono R, Hayashida Y, Matsufuji H, Tsuyama S, et al. Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis. Pediatric surgery international. 2011;27:863-870. doi:10.1007/s00383-011-2853-0 PMID:21290135
    • (2011) Pediatric Surgery International , vol.27 , pp. 863-870
    • Murakami, K.1    Kaji, T.2    Shimono, R.3    Hayashida, Y.4    Matsufuji, H.5    Tsuyama, S.6
  • 31
    • 0021963808 scopus 로고
    • Suppression of experimental hepatic fibrosis by administration of vitamin A
    • 2578584
    • Senoo H, Wake K. Suppression of experimental hepatic fibrosis by administration of vitamin A. Lab Invest. 1985;52:182-194. PMID:2578584
    • (1985) Lab Invest. , vol.52 , pp. 182-194
    • Senoo, H.1    Wake, K.2
  • 33
    • 84873722892 scopus 로고    scopus 로고
    • Effect of 4-methylpyrazole on antioxidant enzyme status and lipid peroxidation in the liver of rats after exposure to ethylene glycol and ethyl alcohol
    • 23406765
    • Sommerfeld K, Zielinska-Psuja B, Przystanowicz J, Kowalowka-Zawieja J, Orlowski J. Effect of 4-methylpyrazole on antioxidant enzyme status and lipid peroxidation in the liver of rats after exposure to ethylene glycol and ethyl alcohol. Pharmacological reports: PR. 2012;64:1547-1553. PMID:23406765
    • (2012) Pharmacological Reports: PR , vol.64 , pp. 1547-1553
    • Sommerfeld, K.1    Zielinska-Psuja, B.2    Przystanowicz, J.3    Kowalowka-Zawieja, J.4    Orlowski, J.5
  • 34
    • 0033833373 scopus 로고    scopus 로고
    • Vitamin A and causes of maternal mortality: Association and biological plausibility
    • 10979152
    • Faisel H, Pittrof R. Vitamin A and causes of maternal mortality: association and biological plausibility. Public Health Nutr. 2000;3:321-327. PMID:10979152
    • (2000) Public Health Nutr. , vol.3 , pp. 321-327
    • Faisel, H.1    Pittrof, R.2
  • 35
    • 0035045741 scopus 로고    scopus 로고
    • Effect of 4-methylpyrazole on endogenous plasma ethanol and methanol levels in humans
    • 11329490
    • Sarkola T, Eriksson CJ. Effect of 4-methylpyrazole on endogenous plasma ethanol and methanol levels in humans. Alcohol Clin Exp Res. 2001;25:513-516. PMID:11329490
    • (2001) Alcohol Clin Exp Res. , vol.25 , pp. 513-516
    • Sarkola, T.1    Eriksson, C.J.2
  • 36
    • 0029882906 scopus 로고    scopus 로고
    • Retinoic acid-stimulated liver stellate cells suppress the production of albumin from parenchymal cells via TGF-beta
    • 8630001
    • Koda H, Okuno M, Imai S, Moriwaki H, Muto Y, Kawada N, et al. Retinoic acid-stimulated liver stellate cells suppress the production of albumin from parenchymal cells via TGF-beta. Biochem Biophys Res Commun. 1996;221:565-569. PMID:8630001
    • (1996) Biochem Biophys Res Commun. , vol.221 , pp. 565-569
    • Koda, H.1    Okuno, M.2    Imai, S.3    Moriwaki, H.4    Muto, Y.5    Kawada, N.6
  • 37
    • 0037095629 scopus 로고    scopus 로고
    • Regulation of the murine alpha (2) (I) collagen promoter by retinoic acid and retinoid X receptors
    • 12054477
    • Wang L, Tankersley LR, Tang M, Potter JJ, Mezey E. Regulation of the murine alpha (2) (I) collagen promoter by retinoic acid and retinoid X receptors. Arch Biochem Biophys. 2002;401:262-270. PMID:12054477
    • (2002) Arch Biochem Biophys. , vol.401 , pp. 262-270
    • Wang, L.1    Tankersley, L.R.2    Tang, M.3    Potter, J.J.4    Mezey, E.5
  • 38
    • 0031892614 scopus 로고    scopus 로고
    • The role of vitamin A and related retinoids in immune function
    • 9564176
    • Semba RD. The role of vitamin A and related retinoids in immune function. Nutr Rev. 1998;56:S38-48. PMID:9564176
    • (1998) Nutr Rev. , vol.56 , pp. S38-S48
    • Semba, R.D.1
  • 39
    • 0027957374 scopus 로고
    • The role of vitamin A in natural killer cell cytotoxicity, number and activation in the rat
    • 8111191
    • Zhao Z, Murasko DM, Ross AC. The role of vitamin A in natural killer cell cytotoxicity, number and activation in the rat. Nat Immun. 1994;13:29-41. PMID:8111191
    • (1994) Nat Immun. , vol.13 , pp. 29-41
    • Zhao, Z.1    Murasko, D.M.2    Ross, A.C.3
  • 40
    • 39549097751 scopus 로고    scopus 로고
    • Liver: An organ with predominant innate immunity
    • 18167066
    • Gao B, Jeong WI, Tian Z. Liver: An organ with predominant innate immunity. Hepatology. 2008;47:729-736. doi:10.1002/hep. 22034 PMID:18167066
    • (2008) Hepatology , vol.47 , pp. 729-736
    • Gao, B.1    Jeong, W.I.2    Tian, Z.3
  • 41
    • 33845644601 scopus 로고    scopus 로고
    • STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity
    • 17133483
    • Jeong WI, Park O, Radaeva S, Gao B. STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity. Hepatology. 2006;44:1441-1451. PMID:17133483
    • (2006) Hepatology , vol.44 , pp. 1441-1451
    • Jeong, W.I.1    Park, O.2    Radaeva, S.3    Gao, B.4
  • 42
    • 0025873420 scopus 로고
    • Abnormal regulation of IFN-gamma secretion in vitamin A deficiency
    • 1907993
    • Carman JA, Hayes CE. Abnormal regulation of IFN-gamma secretion in vitamin A deficiency. J Immunol. 1991;147:1247-1252. PMID:1907993
    • (1991) J Immunol. , vol.147 , pp. 1247-1252
    • Carman, J.A.1    Hayes, C.E.2
  • 43
    • 0029097416 scopus 로고
    • Retinoic acid repletion restores the number of leukocytes and their subsets and stimulates natural cytotoxicity in vitamin A-deficient rats
    • 7643240
    • Zhao Z, Ross AC. Retinoic acid repletion restores the number of leukocytes and their subsets and stimulates natural cytotoxicity in vitamin A-deficient rats. J Nutr. 1995;125:2064-2073. PMID:7643240
    • (1995) J Nutr. , vol.125 , pp. 2064-2073
    • Zhao, Z.1    Ross, A.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.