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Volumn 28, Issue SUPPL 1, 2013, Pages 99-104

Interaction of hepatic stellate cells with diverse types of immune cells: Foe or friend?

Author keywords

Bone marrow cell; Interleukin 17; Macrophage; Natural killer cell; Regulatory T cell

Indexed keywords

CD11B ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 25; INTERLEUKIN 27; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 84880406477     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12017     Document Type: Review
Times cited : (47)

References (57)
  • 2
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol. Rev. 2008; 88: 125-172.
    • (2008) Physiol. Rev. , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 3
    • 51349102719 scopus 로고    scopus 로고
    • Activation of hepatic stellate cells after phagocytosis of lymphocytes: a novel pathway of fibrogenesis
    • Muhanna N, Doron S, Wald O etal. Activation of hepatic stellate cells after phagocytosis of lymphocytes: a novel pathway of fibrogenesis. Hepatology 2008; 48: 963-977.
    • (2008) Hepatology , vol.48 , pp. 963-977
    • Muhanna, N.1    Doron, S.2    Wald, O.3
  • 4
    • 78751472751 scopus 로고    scopus 로고
    • Human T cell microparticles circulate in blood of hepatitis patients and induce fibrolytic activation of hepatic stellate cells
    • Kornek M, Popov Y, Libermann TA, Afdhal NH, Schuppan D. Human T cell microparticles circulate in blood of hepatitis patients and induce fibrolytic activation of hepatic stellate cells. Hepatology 2011; 53: 230-242.
    • (2011) Hepatology , vol.53 , pp. 230-242
    • Kornek, M.1    Popov, Y.2    Libermann, T.A.3    Afdhal, N.H.4    Schuppan, D.5
  • 5
    • 35948958955 scopus 로고    scopus 로고
    • TLR4 enhances TGF-beta signaling and hepatic fibrosis
    • Seki E, De Minicis S, Osterreicher CH etal. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat. Med. 2007; 13: 1324-1332.
    • (2007) Nat. Med. , vol.13 , pp. 1324-1332
    • Seki, E.1    De Minicis, S.2    Osterreicher, C.H.3
  • 6
    • 33644544110 scopus 로고    scopus 로고
    • The liver as an immunological organ
    • Racanelli V, Rehermann B. The liver as an immunological organ. Hepatology 2006; 43: S54-62.
    • (2006) Hepatology , vol.43
    • Racanelli, V.1    Rehermann, B.2
  • 7
    • 39549097751 scopus 로고    scopus 로고
    • Liver: an organ with predominant innate immunity
    • Gao B, Jeong WI, Tian Z. Liver: an organ with predominant innate immunity. Hepatology 2008; 47: 729-736.
    • (2008) Hepatology , vol.47 , pp. 729-736
    • Gao, B.1    Jeong, W.I.2    Tian, Z.3
  • 8
    • 0034113629 scopus 로고    scopus 로고
    • Innate and adaptive lymphoid cells in the human liver
    • Doherty DG, O'Farrelly C. Innate and adaptive lymphoid cells in the human liver. Immunol. Rev. 2000; 174: 5-20.
    • (2000) Immunol. Rev. , vol.174 , pp. 5-20
    • Doherty, D.G.1    O'Farrelly, C.2
  • 9
    • 67650750880 scopus 로고    scopus 로고
    • The liver as a lymphoid organ
    • Crispe IN. The liver as a lymphoid organ. Annu. Rev. Immunol. 2009; 27: 147-163.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 147-163
    • Crispe, I.N.1
  • 11
    • 11144281835 scopus 로고    scopus 로고
    • Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats
    • Imamura M, Ogawa T, Sasaguri Y, Chayama K, Ueno H. Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats. Gastroenterology 2005; 128: 138-146.
    • (2005) Gastroenterology , vol.128 , pp. 138-146
    • Imamura, M.1    Ogawa, T.2    Sasaguri, Y.3    Chayama, K.4    Ueno, H.5
  • 12
    • 67651156353 scopus 로고    scopus 로고
    • CCR2 promotes hepatic fibrosis in mice
    • Seki E, de Minicis S, Inokuchi S etal. CCR2 promotes hepatic fibrosis in mice. Hepatology 2009; 50: 185-197.
    • (2009) Hepatology , vol.50 , pp. 185-197
    • Seki, E.1    de Minicis, S.2    Inokuchi, S.3
  • 13
    • 12644298684 scopus 로고    scopus 로고
    • Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide
    • Casini A, Ceni E, Salzano R etal. Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide. Hepatology 1997; 25: 361-367.
    • (1997) Hepatology , vol.25 , pp. 361-367
    • Casini, A.1    Ceni, E.2    Salzano, R.3
  • 14
    • 0030998255 scopus 로고    scopus 로고
    • Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells
    • Sprenger H, Kaufmann A, Garn H, Lahme B, Gemsa D, Gressner AM. Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells. Gastroenterology 1997; 113: 277-285.
    • (1997) Gastroenterology , vol.113 , pp. 277-285
    • Sprenger, H.1    Kaufmann, A.2    Garn, H.3    Lahme, B.4    Gemsa, D.5    Gressner, A.M.6
  • 15
    • 0031754502 scopus 로고    scopus 로고
    • Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo
    • Maher JJ, Lozier JS, Scott MK. Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo. Am. J. Physiol. 1998; 275: G847-853.
    • (1998) Am. J. Physiol. , vol.275
    • Maher, J.J.1    Lozier, J.S.2    Scott, M.K.3
  • 16
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver CT, Hatton RD, Mangan PR, Harrington LE. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 2007; 25: 821-852.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 17
    • 61949356502 scopus 로고    scopus 로고
    • The interleukin-17 pathway is involved in human alcoholic liver disease
    • Lemmers A, Moreno C, Gustot T etal. The interleukin-17 pathway is involved in human alcoholic liver disease. Hepatology 2009; 49: 646-657.
    • (2009) Hepatology , vol.49 , pp. 646-657
    • Lemmers, A.1    Moreno, C.2    Gustot, T.3
  • 18
    • 84865461464 scopus 로고    scopus 로고
    • Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice
    • e763.
    • Meng F, Wang K, Aoyama T etal. Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice. Gastroenterology 2012; 143: 765-776 e763.
    • (2012) Gastroenterology , vol.143 , pp. 765-776
    • Meng, F.1    Wang, K.2    Aoyama, T.3
  • 19
    • 4444289142 scopus 로고    scopus 로고
    • Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes
    • Safadi R, Ohta M, Alvarez CE etal. Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes. Gastroenterology 2004; 127: 870-882.
    • (2004) Gastroenterology , vol.127 , pp. 870-882
    • Safadi, R.1    Ohta, M.2    Alvarez, C.E.3
  • 20
    • 0037263549 scopus 로고    scopus 로고
    • Peripheral blood T, B, and NK cells in relation to histological hepatitis activity and fibrosis stage in chronic hepatitis C
    • Panasiuk A, Prokopowicz D, Zak J, Wysocka J. Peripheral blood T, B, and NK cells in relation to histological hepatitis activity and fibrosis stage in chronic hepatitis C. Hepatogastroenterology 2003; 50: 178-182.
    • (2003) Hepatogastroenterology , vol.50 , pp. 178-182
    • Panasiuk, A.1    Prokopowicz, D.2    Zak, J.3    Wysocka, J.4
  • 21
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat. Med. 2007; 13: 139-145.
    • (2007) Nat. Med. , vol.13 , pp. 139-145
    • Steinman, L.1
  • 22
    • 70149090633 scopus 로고    scopus 로고
    • Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases
    • Gao B, Radaeva S, Park O. Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases. J. Leukoc. Biol. 2009; 86: 513-528.
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 513-528
    • Gao, B.1    Radaeva, S.2    Park, O.3
  • 23
    • 78751537869 scopus 로고    scopus 로고
    • Accelerated liver fibrosis in hepatitis B virus transgenic mice: involvement of natural killer T cells
    • Jin Z, Sun R, Wei H, Gao X, Chen Y, Tian Z. Accelerated liver fibrosis in hepatitis B virus transgenic mice: involvement of natural killer T cells. Hepatology 2011; 53: 219-229.
    • (2011) Hepatology , vol.53 , pp. 219-229
    • Jin, Z.1    Sun, R.2    Wei, H.3    Gao, X.4    Chen, Y.5    Tian, Z.6
  • 24
    • 79956079647 scopus 로고    scopus 로고
    • CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice
    • Ishikawa S, Ikejima K, Yamagata H etal. CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice. J. Hepatol. 2011; 54: 1195-1204.
    • (2011) J. Hepatol. , vol.54 , pp. 1195-1204
    • Ishikawa, S.1    Ikejima, K.2    Yamagata, H.3
  • 25
    • 66149098871 scopus 로고    scopus 로고
    • Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride
    • Park O, Jeong WI, Wang L etal. Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride. Hepatology 2009; 49: 1683-1694.
    • (2009) Hepatology , vol.49 , pp. 1683-1694
    • Park, O.1    Jeong, W.I.2    Wang, L.3
  • 26
    • 33646372957 scopus 로고    scopus 로고
    • The bone marrow functionally contributes to liver fibrosis
    • Russo FP, Alison MR, Bigger BW etal. The bone marrow functionally contributes to liver fibrosis. Gastroenterology 2006; 130: 1807-1821.
    • (2006) Gastroenterology , vol.130 , pp. 1807-1821
    • Russo, F.P.1    Alison, M.R.2    Bigger, B.W.3
  • 27
    • 1842531265 scopus 로고    scopus 로고
    • A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis
    • Forbes SJ, Russo FP, Rey V etal. A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis. Gastroenterology 2004; 126: 955-963.
    • (2004) Gastroenterology , vol.126 , pp. 955-963
    • Forbes, S.J.1    Russo, F.P.2    Rey, V.3
  • 28
    • 33746494050 scopus 로고    scopus 로고
    • Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis
    • Kisseleva T, Uchinami H, Feirt N etal. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J. Hepatol. 2006; 45: 429-438.
    • (2006) J. Hepatol. , vol.45 , pp. 429-438
    • Kisseleva, T.1    Uchinami, H.2    Feirt, N.3
  • 29
    • 67651174837 scopus 로고    scopus 로고
    • Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis
    • Karlmark KR, Weiskirchen R, Zimmermann HW etal. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology 2009; 50: 261-274.
    • (2009) Hepatology , vol.50 , pp. 261-274
    • Karlmark, K.R.1    Weiskirchen, R.2    Zimmermann, H.W.3
  • 30
    • 32044443617 scopus 로고    scopus 로고
    • Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners
    • Radaeva S, Sun R, Jaruga B, Nguyen VT, Tian Z, Gao B. Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners. Gastroenterology 2006; 130: 435-452.
    • (2006) Gastroenterology , vol.130 , pp. 435-452
    • Radaeva, S.1    Sun, R.2    Jaruga, B.3    Nguyen, V.T.4    Tian, Z.5    Gao, B.6
  • 31
    • 33744939234 scopus 로고    scopus 로고
    • Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC
    • Melhem A, Muhanna N, Bishara A etal. Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC. J. Hepatol. 2006; 45: 60-71.
    • (2006) J. Hepatol. , vol.45 , pp. 60-71
    • Melhem, A.1    Muhanna, N.2    Bishara, A.3
  • 32
    • 33845644601 scopus 로고    scopus 로고
    • STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity
    • Jeong WI, Park O, Radaeva S, Gao B. STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity. Hepatology 2006; 44: 1441-1451.
    • (2006) Hepatology , vol.44 , pp. 1441-1451
    • Jeong, W.I.1    Park, O.2    Radaeva, S.3    Gao, B.4
  • 33
    • 79953752559 scopus 로고    scopus 로고
    • Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice
    • Jeong WI, Park O, Suh YG etal. Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice. Hepatology 2011; 53: 1342-1351.
    • (2011) Hepatology , vol.53 , pp. 1342-1351
    • Jeong, W.I.1    Park, O.2    Suh, Y.G.3
  • 34
    • 33947362952 scopus 로고    scopus 로고
    • Final results of a double-blind, placebo-controlled trial of the antifibrotic efficacy of interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis
    • Pockros PJ, Jeffers L, Afdhal N etal. Final results of a double-blind, placebo-controlled trial of the antifibrotic efficacy of interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis. Hepatology 2007; 45: 569-578.
    • (2007) Hepatology , vol.45 , pp. 569-578
    • Pockros, P.J.1    Jeffers, L.2    Afdhal, N.3
  • 35
    • 84862993192 scopus 로고    scopus 로고
    • NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner
    • Glassner A, Eisenhardt M, Kramer B etal. NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner. Lab. Invest. 2012; 92: 967-977.
    • (2012) Lab. Invest. , vol.92 , pp. 967-977
    • Glassner, A.1    Eisenhardt, M.2    Kramer, B.3
  • 36
    • 84867218760 scopus 로고    scopus 로고
    • Natural killer p46(High) expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver fibrosis
    • Kramer B, Korner C, Kebschull M etal. Natural killer p46(High) expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver fibrosis. Hepatology 2012; 56: 1201-1213.
    • (2012) Hepatology , vol.56 , pp. 1201-1213
    • Kramer, B.1    Korner, C.2    Kebschull, M.3
  • 37
    • 37349108815 scopus 로고    scopus 로고
    • Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis
    • Jeong WI, Park O, Gao B. Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis. Gastroenterology 2008; 134: 248-258.
    • (2008) Gastroenterology , vol.134 , pp. 248-258
    • Jeong, W.I.1    Park, O.2    Gao, B.3
  • 38
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • Petersen BE, Bowen WC, Patrene KD etal. Bone marrow as a potential source of hepatic oval cells. Science 1999; 284: 1168-1170.
    • (1999) Science , vol.284 , pp. 1168-1170
    • Petersen, B.E.1    Bowen, W.C.2    Patrene, K.D.3
  • 39
    • 10644226862 scopus 로고    scopus 로고
    • Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice
    • Sakaida I, Terai S, Yamamoto N etal. Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice. Hepatology 2004; 40: 1304-1311.
    • (2004) Hepatology , vol.40 , pp. 1304-1311
    • Sakaida, I.1    Terai, S.2    Yamamoto, N.3
  • 40
    • 33749507049 scopus 로고    scopus 로고
    • Improved liver function in patients with liver cirrhosis after autologous bone marrow cell infusion therapy
    • Terai S, Ishikawa T, Omori K etal. Improved liver function in patients with liver cirrhosis after autologous bone marrow cell infusion therapy. Stem Cells 2006; 24: 2292-2298.
    • (2006) Stem Cells , vol.24 , pp. 2292-2298
    • Terai, S.1    Ishikawa, T.2    Omori, K.3
  • 41
    • 84868203631 scopus 로고    scopus 로고
    • CD11b(+) Gr1(+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice
    • Suh YG, Kim JK, Byun JS etal. CD11b(+) Gr1(+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice. Hepatology 2012; 56: 1902-1912.
    • (2012) Hepatology , vol.56 , pp. 1902-1912
    • Suh, Y.G.1    Kim, J.K.2    Byun, J.S.3
  • 42
    • 79957465441 scopus 로고    scopus 로고
    • Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function
    • Thomas JA, Pope C, Wojtacha D etal. Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function. Hepatology 2011; 53: 2003-2015.
    • (2011) Hepatology , vol.53 , pp. 2003-2015
    • Thomas, J.A.1    Pope, C.2    Wojtacha, D.3
  • 43
    • 34547214205 scopus 로고    scopus 로고
    • Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
    • Roncarolo MG, Battaglia M. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat. Rev. Immunol. 2007; 7: 585-598.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 585-598
    • Roncarolo, M.G.1    Battaglia, M.2
  • 44
    • 33646000803 scopus 로고    scopus 로고
    • Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis
    • Lan RY, Cheng C, Lian ZX etal. Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis. Hepatology 2006; 43: 729-737.
    • (2006) Hepatology , vol.43 , pp. 729-737
    • Lan, R.Y.1    Cheng, C.2    Lian, Z.X.3
  • 45
    • 40049091455 scopus 로고    scopus 로고
    • Intrahepatic status of regulatory T cells in autoimmune liver diseases and chronic viral hepatitis
    • Sakaki M, Hiroishi K, Baba T etal. Intrahepatic status of regulatory T cells in autoimmune liver diseases and chronic viral hepatitis. Hepatol. Res. 2008; 38: 354-361.
    • (2008) Hepatol. Res. , vol.38 , pp. 354-361
    • Sakaki, M.1    Hiroishi, K.2    Baba, T.3
  • 47
    • 79952211990 scopus 로고    scopus 로고
    • Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice
    • Chou HS, Hsieh CC, Yang HR etal. Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice. Hepatology 2011; 53: 1007-1019.
    • (2011) Hepatology , vol.53 , pp. 1007-1019
    • Chou, H.S.1    Hsieh, C.C.2    Yang, H.R.3
  • 48
    • 84860318483 scopus 로고    scopus 로고
    • Selective expansion of allogeneic regulatory T cells by hepatic stellate cells: role of endotoxin and implications for allograft tolerance
    • Dangi A, Sumpter TL, Kimura S etal. Selective expansion of allogeneic regulatory T cells by hepatic stellate cells: role of endotoxin and implications for allograft tolerance. J. Immunol. 2012; 188: 3667-3677.
    • (2012) J. Immunol. , vol.188 , pp. 3667-3677
    • Dangi, A.1    Sumpter, T.L.2    Kimura, S.3
  • 49
    • 84865564349 scopus 로고    scopus 로고
    • Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice
    • Kong X, Feng D, Wang H etal. Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice. Hepatology 2012; 56: 1150-1159.
    • (2012) Hepatology , vol.56 , pp. 1150-1159
    • Kong, X.1    Feng, D.2    Wang, H.3
  • 51
    • 84862260797 scopus 로고    scopus 로고
    • Human amniotic epithelial cell transplantation induces markers of alternative macrophage activation and reduces established hepatic fibrosis
    • Manuelpillai U, Lourensz D, Vaghjiani V etal. Human amniotic epithelial cell transplantation induces markers of alternative macrophage activation and reduces established hepatic fibrosis. PLoS One 2012; 7: e38631.
    • (2012) PLoS One , vol.7
    • Manuelpillai, U.1    Lourensz, D.2    Vaghjiani, V.3
  • 52
    • 34247149014 scopus 로고    scopus 로고
    • Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis
    • Fallowfield JA, Mizuno M, Kendall TJ etal. Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis. J. Immunol. 2007; 178: 5288-5295.
    • (2007) J. Immunol. , vol.178 , pp. 5288-5295
    • Fallowfield, J.A.1    Mizuno, M.2    Kendall, T.J.3
  • 53
    • 70449355084 scopus 로고    scopus 로고
    • In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha
    • Connolly MK, Bedrosian AS, Mallen-St Clair J etal. In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha. J. Clin. Invest. 2009; 119: 3213-3225.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3213-3225
    • Connolly, M.K.1    Bedrosian, A.S.2    Mallen-St Clair, J.3
  • 54
    • 84155175629 scopus 로고    scopus 로고
    • Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression
    • Jiao J, Sastre D, Fiel MI etal. Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression. Hepatology 2012; 55: 244-255.
    • (2012) Hepatology , vol.55 , pp. 244-255
    • Jiao, J.1    Sastre, D.2    Fiel, M.I.3
  • 55
    • 80054872790 scopus 로고    scopus 로고
    • Alcoholic liver disease: pathogenesis and new therapeutic targets
    • Gao B, Bataller R. Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology 2011; 141: 1572-1585.
    • (2011) Gastroenterology , vol.141 , pp. 1572-1585
    • Gao, B.1    Bataller, R.2
  • 56
    • 38649114788 scopus 로고    scopus 로고
    • Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
    • Jeong WI, Osei-Hyiaman D, Park O etal. Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab. 2008; 7: 227-235.
    • (2008) Cell Metab. , vol.7 , pp. 227-235
    • Jeong, W.I.1    Osei-Hyiaman, D.2    Park, O.3
  • 57
    • 84863082047 scopus 로고    scopus 로고
    • Retinoic acids and hepatic stellate cells in liver disease
    • Lee YS, Jeong WI. Retinoic acids and hepatic stellate cells in liver disease. J. Gastroenterol. Hepatol. 2012; 27 (Suppl. 2): 75-79.
    • (2012) J. Gastroenterol. Hepatol. , vol.27 , Issue.SUPPL. 2 , pp. 75-79
    • Lee, Y.S.1    Jeong, W.I.2


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