An enhanced chimeric firefly luciferase-inspired enzyme for ATP detection and bioluminescence reporter and imaging applications

Analytical Biochemistry

Volumn 484, Issue , 2015, Pages 148-153

  Branchini, Bruce R ^a   Southworth, Tara L ^a   Fontaine, Danielle M ^a   Kohrt, Dawn ^a   Talukder, Munya ^a   Michelini, Elisa ^b   Cevenini, Luca ^b   Roda, Aldo ^b   Grossel, Martha J ^a  

^a The Holleran Center for Community Action and Public Policy   (United States)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

ATP; Bioluminescence; Imaging; luc2; Luciferase; Reporter

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOLUMINESCENCE; CYTOLOGY; ENZYMES; GENES; IMAGING TECHNIQUES; MAMMALS; PHOSPHORESCENCE; THERMAL ENGINEERING;

CHIMERIC ENZYMES; DEPENDENT PROCESS; FIREFLY LUCIFERASE; IMAGING APPLICATIONS; LUC2; LUCIFERASE; REPORTER; WHOLE-CELL BIOSENSORS;

PLANTS (BOTANY);

ADENOSINE TRIPHOSPHATE; COMPLEMENTARY DNA; FIREFLY LUCIFERASE; HYBRID PROTEIN; LUCIFERASE, PHOTINUS;

ARTICLE; BIOLUMINESCENCE; CELL LYSATE; CYTOLYSIS; ENVIRONMENTAL TEMPERATURE; ENZYME ASSAY; ENZYME ENGINEERING; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIMIT OF DETECTION; LUCIOLA ITALICA; MOLECULAR IMAGING; NUCLEIC ACID ANALYSIS; PH; PRIORITY JOURNAL; RED LIGHT; THERMOSTABILITY; ANIMAL; ENZYME STABILITY; ENZYMOLOGY; FIREFLY; GENETICS; LUMINESCENCE; METABOLISM; PROCEDURES; PROTEIN ENGINEERING; REPORTER GENE; TEMPERATURE;

LUCIOLA; MAMMALIA; PHOTINUS PYRALIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ENZYME STABILITY; FIREFLIES; GENES, REPORTER; HEK293 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; LUCIFERASES, FIREFLY; LUMINESCENT MEASUREMENTS; MOLECULAR IMAGING; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; TEMPERATURE;

EID: 84934918306     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2015.05.020     Document Type: Article

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