Bioluminescence imaging in vivo - Application to cancer research

Expert Opinion on Biological Therapy

Volumn 3, Issue 7, 2003, Pages 1163-1172

  Söling, Ariane ^a,b   Rainov, Nikolai G ^b,c  

^a Molecular Neurooncology Laboratory   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Bioluminescence; Cancer; Luciferase; Optical imaging; Tumour

Indexed keywords

ANTINEOPLASTIC AGENT; CARMUSTINE; DOXORUBICIN; FIALURIDINE; HUMAN MONOCLONAL ANTIBODY; PACLITAXEL; PROTEIN TYROSINE KINASE INHIBITOR; RETROVIRUS VECTOR; SUNITINIB; T LYMPHOCYTE RECEPTOR; TRASTUZUMAB; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; BIOLUMINESCENCE; CANCER; CANCER CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CANCER RESEARCH; CANCER THERAPY; CELL CULTURE; CONTROLLED STUDY; CYTOKINE INDUCED KILLER CELL; DRUG TARGETING; EPITHELIUM TUMOR; FLUORESCENCE; GENE THERAPY; GENETIC TRANSCRIPTION; GLIOMA; HERPES SIMPLEX VIRUS; IMAGING SYSTEM; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PROSTATE CANCER; RAT; REVIEW; TREATMENT OUTCOME; TUMOR GROWTH; TUMOR VOLUME; UTERINE CERVIX CARCINOMA;

ANIMALIA; SIMPLEXVIRUS; UNIDENTIFIED RETROVIRUS;

EID: 17644433750     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.3.7.1163     Document Type: Review

References (49)

1. MCELROY WD, DELUCA M: Firefly luminescence. In: Chemi- and Bioluminescence. Burr JG (Ed), Dekker, New York (1985):387-399.
2. GROSKREUTZ DJ, SHERF BA, WOOD KV, SCHENBORN ET: Increased expression and convenience with the new pGL3 ludferase reporter vectors. Promega Notes Mag. (1995) 50:2-7.
3. WOOD KV, LAM YA, MCELROY WD: Introduction to beede luciferases and their applications. J. Biolum. Chemilum. (1989) 4:289-301.
4. WANG W, EL-DEIRY WS: Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model. Cancer Biol. Ther. (2003) 2:196-202.
5. EDINGER M, CAO YA, HORNIG YS et al.: Advancing animal models of neoplasia through in vivo bioluminescence imaging. Eur. J. Cancer (2002) 38:2128-2136.
6. REHEMTULLA A, HALL DE, STEGMAN LD et al.: Molecular imaging of gene expression and efficacy following adenoviral-mediated brain tumor gene therapy. Mol. Imag. (2002) 1:43-55.
7. VOOIJS M, JONKERS J, LYONS S, BERNS A: Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice. Cancer Res. (2002) 62:1862-1867.
8. EDINGER M, SWEENEY TJ, TUCKER AA, OLOMU AB, NEGRIN RS, CONTAG CH: Noninvasive assessment of tumor cell proliferation in animal models. Neoplasia (1999) 1:303-310.
9. DE A, LEWIS XZ, GAMBHIR SS: Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice. Mol. Ther. (2003) 7:681-691.
10. LIPSHUTZ GS, GRUBER CA, CAO YA, HARDY J, CONTAG CH, GAENSLER KM: In utero delivery of adeno-associated viral vectors: intraperitoneal gene transfer produces long-term expression. Mol. Ther. (2001) 3:284-292.
11. REHEMTULLA A, STEGMAN LD, CARDOZO SJ et al.: Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia (2000) 2:491-495.
12. HONIGMAN A, ZEIRA E, OHANA P et al.: Imaging transgene expression in live animals. Mol. Ther. (2001) 4:239-249.
13. CONTAG PR: Whole-animal cellular and molecular imaging to accelerate drug development. Drug Discov. Today (2002) 7:555-562.
14. MASSOUD TF, GAMBHIR SS: Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. (2003) 17:545-580.
15. EDINGER M, CAO Y, VERNERIS MR, BACHMANN MH, CONTAG CH, NEGRIN RS: Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging. Blood (2003) 101:640-648.
16. EL HILALI N, RUBIO N, MARTINEZ-VILLACAMPA M, BLANCO J: Combined noninvasive imaging and luminometric quantification of luciferase-labeled human prostate tumors and metastases. Lab. Invest. (2002) 82:1563-1571.
17. WU JC, SUNDARESAN G, IYER M, GAMBHIR SS: Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. Mol. Ther. (2001) 4:297-306.
18. CONTAG CH, SPILMAN SD, CONTAG PR, OSHIRO M, STEVENSON DK, BENARON DA: Photonic detection of bacterial pathogens in living hosts. Mol. Microbiol. (1995) 18:593-603.
19. COLIN M, MORITZ S, SCHNEIDER H, CAPEAU J, COUTELLE C, BRAHIMI-HORN MC: Haemoglobin interferes with the ex vivo luminescence assay: consequence for detection of luciferase reporter gene expression in vivo. Gene Ther. (2000) 7:1333-1336.
20. NYATI MK, KIEVIT E, DORNFELD KJ et al: The potential of 5-fluorocytosine/ cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model. Gene Ther. (2002) 9:844-849.
21. MENDEL DB, LAIRD AD, XIN X et al.: In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic pharmacodynamic relationship. Clin. Cancer Res. (2003) 9:327-337.
22. HILDEBRANDT IJ, IYER M, WAGNER E, GAMBHIR SS: Optical imaging of transferrin targeted PEI/DNA complexes in living subjects. Gene Ther. (2003) 10:758-764.
23. ADAMS JY, JOHNSON M, SATO M et al: Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging. Nat. Med. (2002) 8:891-896.
24. ANDREOTTI PE: Luminescence applications for chemotherapeutic drug development. Recent Results Cancer Res. (2003) 161:3-12.
25. WETTERWALD A, VAN DER PLUIJM G, QUE I et al.: Optical imaging of cancer metastasis to bone marrow. Am. J. Pathol. (2002) 160:1143-1153.
26. ROSOL TJ, TANNEHILL-GREGG SH, LEROY BE, MANDL S, CONTAG CH: Animal models of bone metastasis. Cancer (2003) 97(3 Suppl.):748-757.
27. LAXMAN B, HALL DE, BHOJANI MS et al.: Noninvasive real-time imaging of apoptosis. Proc. Natl. Acad. Sci. USA (2002) 99:16551-16555.
28. SCHUETZ E, LAN L, YASUDA K et al.: Development of a real-time in vivo transcription assay: application reveals pregnane X receptor-mediated induction of CYP3A4 by cancer chemotherapeutic agents. Mol. Pharmacol. (2002) 62:439-445.
29. RELLING MV, PUI CH, SANDLUND JT et al.: Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia. Lancet (2000) 356:285-290.
30. BHAUMIK S, GAMBHIR SS: Optical imaging of renilla luciferase reporter gene expression in living mice. Proc. Natl. Acad. Sci. USA (2002) 99:377-382.
31. IYER M, WU L, CAREY M, WANG Y, SMALLWOOD A, GAMBHIR SS: Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters. Proc. Natl. Acad Sci. USA (2001) 98:14595-14600.
32. ZHANG L, ADAMS JY, BILLICK E et al.: Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer. Mol. Ther. (2002) 5:223-232.
33. TRAXLER P: Tyrosine kinases as targers in cancer therapy - successes and failures. Expert Opin. Ther. Targets (2003) 7:215-234.
34. SWEENEY TJ, MAILÄNDER V, TUCKER AA et al.: Visualizing the kinetics of tumor-cell clearance in living animals. Proc. Natl. Acad Sci. USA (1999) 96:12044-12049.
35. 2HER2xCD3. Cancer Res. (2002) 62:5785-5791.
36. MANDL S, SCHIMMELPFENNIG C, EDINGER M, NEGRIN RS, CONTAG CH: Understanding immune cell trafficking patterns via in vivo bioluminescence imaging. J. Cell. Biochem. Suppl. (2002) 39:239-248.
37. HARDY J, EDINGER M, BACHMANN MH, NEGRIN RS, FATHMAN CG, CONTAG CH: Bioluminescence imaging of lymphocyte trafficking in vivo. Exp. Hematol. (2001) 29:1353-1360.
38. RAM Z, CULVER KW, OSHIRO EM et al.: Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat. Med. (1997) 3:1354-1361.
39. RAINOV NG: A Phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and gancidovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther. (2000) 11:2389-2401.
40. GAMBHIR SS: Molecular imaging of cancer with positron emission tomography. Nat. Rev. Cancer (2002) 2:682-693.
41. RAY P, WU AM, GAMBHIR SS: Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in rumor xenografts of living mice. Cancer Res. (2003) 63:1160-1165.
42. HOFFMAN RM: In vivo imaging of metastatic cancer with fluorescent proteins. Cell Death Difer. (2002) 9:786-789.
43. WEISSLEDER R, TUNG CH, MAHMOOD U, BOGDANOV A: In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat. Biotech. (1999) 17:375-378.
44. GAMBOTTO A, DWORACKI G, CICINNATI V et al.: Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: identification of an H2-Kd-restricted CTL epitope. Gene Ther. (2000) 7:2036-2040.
45. EAMES BF, BENARON DA, STEVENSON DK, CONTAG CH: Construction and characterization of a redemitting luciferase. SPIE (1999) 3600:36-39.
46. CRAIG FF, SIMMONDS AC, WATMORE D, MCCAPRA F, WHITE MRH: Membrane-permeable luciferin-esters for assay of firefly luciferase in live intact cells. Biochem. J. (1991) 76:637-641.
47. WANG Y, WANG G, O'KANE DJ, SZALAY AA: A study of protein-protein interactions in living cells using luminescence resonance energy transfer (LRET) from Renilla luciferase to Aequorea GFP. Mol. Gen. Genet. (2001) 256:578-587.
48. OZAWA T, KAIHARA A, SATO M, TACHIHARA K, UMEZAWA Y: Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing. Anal. Chem. (2001) 11:2516-2521.
49. PAULMURUGAN R, UMEZAWA Y, GAMBHIR SS: Noninvasive imaging of protein-protein interactions in living subjects by using reporter complementation and reconstitution strategies. Proc. Natl. Acad. Sci. USA (2002) 99:15608-15613.