Studies of OC-STAMP in osteoclast fusion: A new knockout mouse model, rescue of cell fusion, and transmembrane topology

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Witwicka, Hanna ^a   Hwang, Sung Yong ^a,e   Reyes Gutierrez, Pablo ^a   Jia, Hong ^a,f   Odgren, Paul E ^b   Donahue, Leah Rae ^c   Birnbaum, Mark J ^d   Odgren, Paul R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b Parallax Pictures   (United States)

^c JACKSON LABORATORY   (United States)

^d MERRIMACK COLLEGE   (United States)

^e CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE II; CATHEPSIN K; COLONY STIMULATING FACTOR 1; MEMBRANE PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN OC STAMP; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ACP5 PROTEIN, MOUSE; BIOLOGICAL MARKER; ISOENZYME; OC-STAMP PROTEIN, MOUSE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MONONUCLEAR CELL; BONE TURNOVER; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL FUSION; CELL VIABILITY; CLASSIFICATION ALGORITHM; CONTROLLED STUDY; DENDRITIC CELL; GENE FREQUENCY; GLYCOSYLATION; HOMOZYGOSITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE PERMEABILITY; MEMBRANE STRUCTURE; METAPHYSIS; MOLECULAR CLONING; MONONUCLEAR CELL; MOUSE; MUTAGENESIS; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; POLYMERASE CHAIN REACTION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN STABILITY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; ALLELE; AMINO ACID SEQUENCE; ANIMAL; BONE DEVELOPMENT; C57BL MOUSE; CELL SURVIVAL; CHEMISTRY; CONSERVED SEQUENCE; CYTOLOGY; DEFICIENCY; ENZYMOLOGY; FEMUR; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; HEK293 CELL LINE; KNOCKOUT MOUSE; LENTIVIRINAE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PROTEIN MOTIF;

MUS; VERTEBRATA;

ACID PHOSPHATASE; ALLELES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BIOMARKERS; BONE RESORPTION; CELL FUSION; CELL SURVIVAL; CONSERVED SEQUENCE; FEMUR; GENE EXPRESSION REGULATION; GLYCOSYLATION; HEK293 CELLS; HUMANS; ISOENZYMES; LENTIVIRUS; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; OSTEOCLASTS; OSTEOGENESIS; TARTRATE-RESISTANT ACID PHOSPHATASE; TRANSDUCTION, GENETIC;

EID: 84934913141     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0128275     Document Type: Article

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