메뉴 건너뛰기




Volumn 61, Issue 1, 1996, Pages 48-60

Product of the oncogene-activating gene Tpr is a phosphorylated protein of the nuclear pore complex

Author keywords

coiled coil proteins; digitonin permeabilization; immunofluorescence; nuclear pore structure; Tpr

Indexed keywords

GENE PRODUCT; HYBRID PROTEIN;

EID: 0029923398     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960401)61:1<48::AID-JCB7>3.0.CO;2-2     Document Type: Article
Times cited : (21)

References (51)
  • 1
    • 0024581538 scopus 로고
    • Identification of specific binding proteins for a nuclear location sequence
    • Adam SA, Lobl TJ, Mitchell MA, Gerace L (1989): Identification of specific binding proteins for a nuclear location sequence. Nature 337:276-279.
    • (1989) Nature , vol.337 , pp. 276-279
    • Adam, S.A.1    Lobl, T.J.2    Mitchell, M.A.3    Gerace, L.4
  • 2
    • 0025083331 scopus 로고
    • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
    • Adam SA, Marr RS, Gerace L (1990): Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J Cell Biol 111:807-816.
    • (1990) J Cell Biol , vol.111 , pp. 807-816
    • Adam, S.A.1    Marr, R.S.2    Gerace, L.3
  • 3
    • 0024417594 scopus 로고
    • Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy
    • Akey CW (1989): Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy. J Cell Biol 109:955-970.
    • (1989) J Cell Biol , vol.109 , pp. 955-970
    • Akey, C.W.1
  • 4
    • 0027287349 scopus 로고
    • Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy
    • Akey CW, Radermacher M (1993): Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy. J Cell Biol 122:1-19.
    • (1993) J Cell Biol , vol.122 , pp. 1-19
    • Akey, C.W.1    Radermacher, M.2
  • 5
    • 0026693017 scopus 로고
    • The molecular biology of intermediate filament proteins
    • Albers K, Fuchs E (1992): The molecular biology of intermediate filament proteins. Int Rev Cytol 134:243-279.
    • (1992) Int Rev Cytol , vol.134 , pp. 243-279
    • Albers, K.1    Fuchs, E.2
  • 6
    • 0344338368 scopus 로고
    • Gene gating: A hypothesis
    • Blobel G (1985): Gene gating: a hypothesis. Proc Natl Acad Sci USA 82:8527-8529.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8527-8529
    • Blobel, G.1
  • 7
    • 0028091980 scopus 로고
    • Tpr, a large coiled coil protein whose amino terminus is involved in the activation of oncogenic kinases, is localized to the cytoplasmic face of the nuclear pore complex
    • Byrd DA, Sweet DA, Pante N, Konstantinov KN, Guan T, Saphire ACS, Mitchell PJ, Cooper CS, Aebi U, Gerace L (1994): Tpr, a large coiled coil protein whose amino terminus is involved in the activation of oncogenic kinases, is localized to the cytoplasmic face of the nuclear pore complex. J Cell Biol 127:1315-1526.
    • (1994) J Cell Biol , vol.127 , pp. 1315-1526
    • Byrd, D.A.1    Sweet, D.A.2    Pante, N.3    Konstantinov, K.N.4    Guan, T.5    Saphire, A.C.S.6    Mitchell, P.J.7    Cooper, C.S.8    Aebi, U.9    Gerace, L.10
  • 9
    • 0025272940 scopus 로고
    • Alpha-helical coiled coils and bundles: How to design an alpha-helical protein
    • Cohen C, Parry DA (1990): Alpha-helical coiled coils and bundles: how to design an alpha-helical protein. Proteins 7:1-15.
    • (1990) Proteins , vol.7 , pp. 1-15
    • Cohen, C.1    Parry, D.A.2
  • 11
    • 0025223824 scopus 로고
    • Identification of a soluble precursor complex essential for nuclear pore assembly in vitro
    • Dabauvalle MC, Loos K, Scheer U (1990): Identification of a soluble precursor complex essential for nuclear pore assembly in vitro. Chromosoma 100:56-66.
    • (1990) Chromosoma , vol.100 , pp. 56-66
    • Dabauvalle, M.C.1    Loos, K.2    Scheer, U.3
  • 12
    • 0023449881 scopus 로고
    • Nuclear pore complex contains a family of glycoproteins that includes p62: Glycosylation through a previously unidentified cellular pathway
    • Davis LI, Blobel G (1987): Nuclear pore complex contains a family of glycoproteins that includes p62: Glycosylation through a previously unidentified cellular pathway. Proc Natl Acad Sci USA 84:7552-7556.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7552-7556
    • Davis, L.I.1    Blobel, G.2
  • 13
    • 0025367662 scopus 로고
    • The NUP1 gene encodes an essential component of the yeast nuclear pore complex
    • Davis LI, Fink GR (1990): The NUP1 gene encodes an essential component of the yeast nuclear pore complex. Cell 61:965-978.
    • (1990) Cell , vol.61 , pp. 965-978
    • Davis, L.I.1    Fink, G.R.2
  • 14
    • 0027978528 scopus 로고
    • Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif
    • Fahre E, Boelens WC, Wimmer C, Mattaj IW, Hurt EC (1994): Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif. Cell 78:275-289.
    • (1994) Cell , vol.78 , pp. 275-289
    • Fahre, E.1    Boelens, W.C.2    Wimmer, C.3    Mattaj, I.W.4    Hurt, E.C.5
  • 15
    • 0024094997 scopus 로고
    • A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo
    • Featherstone C, Darby MK, Gerace L (1988): A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo. J Cell Biol 107:1289-1297.
    • (1988) J Cell Biol , vol.107 , pp. 1289-1297
    • Featherstone, C.1    Darby, M.K.2    Gerace, L.3
  • 16
    • 0023704381 scopus 로고
    • Nuclear matrix proteins reflect cell type of origin in cultured human cells
    • Fey EG, Penman S (1988): Nuclear matrix proteins reflect cell type of origin in cultured human cells. Proc Natl Acad Sci USA 85:121-125.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 121-125
    • Fey, E.G.1    Penman, S.2
  • 17
    • 0021244964 scopus 로고
    • Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: Three-dimensional organization and protein composition
    • Fey EG, Wan KM, Penman S (1984): Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: Three-dimensional organization and protein composition. J Cell Biol 98:1973-1984.
    • (1984) J Cell Biol , vol.98 , pp. 1973-1984
    • Fey, E.G.1    Wan, K.M.2    Penman, S.3
  • 18
    • 0026676877 scopus 로고
    • Structure and function of the nuclear pore complex
    • Forbes DJ (1992): Structure and function of the nuclear pore complex. (Review.) Annu Rev Cell Biol 8:495-527.
    • (1992) Annu Rev Cell Biol , vol.8 , pp. 495-527
    • Forbes, D.J.1
  • 19
    • 0024147084 scopus 로고
    • Functional organization of the nuclear envelope
    • Gerace L, Burke B (1988): Functional organization of the nuclear envelope. (Review.) Annu Rev Cell Biol 4:335-374.
    • (1988) Annu Rev Cell Biol , vol.4 , pp. 335-374
    • Gerace, L.1    Burke, B.2
  • 20
    • 0027104231 scopus 로고
    • High resolution scanning electron microscopy of the nuclear envelope: Demonstration of a new, regular, fibrous lattice attached to the baskets of the nucleoplasmic face of the nuclear pores
    • Goldberg MW, Allen TD (1992): High resolution scanning electron microscopy of the nuclear envelope: demonstration of a new, regular, fibrous lattice attached to the baskets of the nucleoplasmic face of the nuclear pores. J Cell Biol 119:1429-1440.
    • (1992) J Cell Biol , vol.119 , pp. 1429-1440
    • Goldberg, M.W.1    Allen, T.D.2
  • 22
    • 0026600358 scopus 로고
    • TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas
    • Greco A, Pierotti MA, Bongarzone I, Pagliardini S, Lanzi C, Della Porta G (1992): TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas. Oncogene 7:237-242.
    • (1992) Oncogene , vol.7 , pp. 237-242
    • Greco, A.1    Pierotti, M.A.2    Bongarzone, I.3    Pagliardini, S.4    Lanzi, C.5    Della Porta, G.6
  • 23
    • 0026776959 scopus 로고
    • Architecture and design of the nuclear pore complex
    • Hinshaw JE, Carragher BO, Milligan RA (1992): Architecture and design of the nuclear pore complex. Cell 69:1133-1141.
    • (1992) Cell , vol.69 , pp. 1133-1141
    • Hinshaw, J.E.1    Carragher, B.O.2    Milligan, R.A.3
  • 24
    • 0023225084 scopus 로고
    • Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine
    • Holt GD, Snow CM, Senior A, Haltiwanger RS, Gerace L, Hart GW (1987): Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine. J Cell Biol 104:1157-1164.
    • (1987) J Cell Biol , vol.104 , pp. 1157-1164
    • Holt, G.D.1    Snow, C.M.2    Senior, A.3    Haltiwanger, R.S.4    Gerace, L.5    Hart, G.W.6
  • 25
    • 0026323478 scopus 로고
    • Toward a more complete 3-D structure of the nuclear pore complex
    • Jarnik M, Aebi U (1991): Toward a more complete 3-D structure of the nuclear pore complex. J Struct Biol 107: 291-308.
    • (1991) J Struct Biol , vol.107 , pp. 291-308
    • Jarnik, M.1    Aebi, U.2
  • 27
    • 0016756272 scopus 로고
    • Continuous culture of fused cells secreting antibody of predefined specificity
    • Koehler G, Milstein C (1975): Continuous culture of fused cells secreting antibody of predefined specificity. Nature 256:495-497.
    • (1975) Nature , vol.256 , pp. 495-497
    • Koehler, G.1    Milstein, C.2
  • 28
    • 0027979480 scopus 로고
    • The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm
    • Kraemer D, Wozniak RW, Blobel G, Radu A (1994): The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm. Proc Natl Acad Sci USA 91:1519-1523.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1519-1523
    • Kraemer, D.1    Wozniak, R.W.2    Blobel, G.3    Radu, A.4
  • 29
    • 0021678736 scopus 로고
    • Electroblotting of multiple gels: A simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose
    • Kyhse-Andersen J (1984): Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. J Biochem Biophys Methods 10:203-209.
    • (1984) J Biochem Biophys Methods , vol.10 , pp. 203-209
    • Kyhse-Andersen, J.1
  • 30
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970): Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 31
    • 0028853451 scopus 로고
    • Differential mitotic phosphorylation of proteins of the nuclear pore complex
    • Macaulay C, Meier E, Forbes DJ (1995): Differential mitotic phosphorylation of proteins of the nuclear pore complex. J Biol Chem 270:254-262.
    • (1995) J Biol Chem , vol.270 , pp. 254-262
    • Macaulay, C.1    Meier, E.2    Forbes, D.J.3
  • 33
    • 0026439405 scopus 로고
    • The human tpr gene encodes a protein of 2094 amino acids that has extensive coiled-coil regions and an acidic C-terminal domain
    • Mitchell PJ, Cooper CS (1992): The human tpr gene encodes a protein of 2094 amino acids that has extensive coiled-coil regions and an acidic C-terminal domain. Oncogene 7:2329-2333.
    • (1992) Oncogene , vol.7 , pp. 2329-2333
    • Mitchell, P.J.1    Cooper, C.S.2
  • 34
    • 0027199147 scopus 로고
    • The nuclear pore complex
    • Pante N, Aebi U (1993): The nuclear pore complex. (Review.) J Cell Biol 122:977-984.
    • (1993) J Cell Biol , vol.122 , pp. 977-984
    • Pante, N.1    Aebi, U.2
  • 35
    • 0027931054 scopus 로고
    • Interactions and three-dimensional localization of a group of nuclear pore complex proteins
    • Pante N, Bastos R, McMorrow I, Burke B, Aebi U (1994): Interactions and three-dimensional localization of a group of nuclear pore complex proteins J Cell Biol 126:603-617.
    • (1994) J Cell Biol , vol.126 , pp. 603-617
    • Pante, N.1    Bastos, R.2    McMorrow, I.3    Burke, B.4    Aebi, U.5
  • 37
    • 0028338928 scopus 로고
    • Nup107 is a novel nuclear pore complex protein that contains a leucine zipper
    • Radu A, Blobel G, Wozniak RW (1994): Nup107 is a novel nuclear pore complex protein that contains a leucine zipper. J Biol Chem 269:17600-17605.
    • (1994) J Biol Chem , vol.269 , pp. 17600-17605
    • Radu, A.1    Blobel, G.2    Wozniak, R.W.3
  • 38
    • 0029021567 scopus 로고
    • The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
    • Radu A, Moore MS, Blobel G (1995): The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. Cell 81:215-222.
    • (1995) Cell , vol.81 , pp. 215-222
    • Radu, A.1    Moore, M.S.2    Blobel, G.3
  • 39
    • 0025247954 scopus 로고
    • Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components
    • Reichelt R, Holzenburg A, Buhle E Jr, Jarnik M, Engel A, Aebi U (1990): Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components. J Cell Biol 110:883-894.
    • (1990) J Cell Biol , vol.110 , pp. 883-894
    • Reichelt, R.1    Holzenburg, A.2    Buhle Jr., E.3    Jarnik, M.4    Engel, A.5    Aebi, U.6
  • 40
    • 0027369598 scopus 로고
    • Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase
    • Rodrigues GA, Park M (1993) Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase. Mol Cell Biol 13:6711-6722.
    • (1993) Mol Cell Biol , vol.13 , pp. 6711-6722
    • Rodrigues, G.A.1    Park, M.2
  • 41
    • 0027989786 scopus 로고
    • Pores for thought: Nuclear pore complex proteins
    • Rout MP, Wente SR (1994): Pores for thought: nuclear pore complex proteins. Trends Cell Biol 4:357-365.
    • (1994) Trends Cell Biol , vol.4 , pp. 357-365
    • Rout, M.P.1    Wente, S.R.2
  • 43
    • 0023257987 scopus 로고
    • Monoclonal antibodies identify a group of nuclear pore complex glycoproteins
    • Snow CM, Senior A, Gerace L (1987): Monoclonal antibodies identify a group of nuclear pore complex glycoproteins. J Cell Biol 104:1143-1156.
    • (1987) J Cell Biol , vol.104 , pp. 1143-1156
    • Snow, C.M.1    Senior, A.2    Gerace, L.3
  • 44
    • 0027458374 scopus 로고
    • A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm
    • Sukegawa J, Blobel G (1993): A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm. Cell 72:29-38.
    • (1993) Cell , vol.72 , pp. 29-38
    • Sukegawa, J.1    Blobel, G.2
  • 45
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin HT, Staehlin, Gordon (1979): Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4350-4354
    • Towbin, H.T.1    Staehlin2    Gordon3
  • 46
    • 0026560593 scopus 로고
    • The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA
    • von Lindern M, Fornerod M, van Baal S, Jaegle M, de Wit T, Buijs A, Grosveld G (1992a): The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell Biol 12:1687-1697.
    • (1992) Mol Cell Biol , vol.12 , pp. 1687-1697
    • Von Lindern, M.1    Fornerod, M.2    Van Baal, S.3    Jaegle, M.4    De Wit, T.5    Buijs, A.6    Grosveld, G.7
  • 47
    • 0026693436 scopus 로고
    • Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3′ half to different genes: Characterization of the set gene
    • von Lindern M, van Baal S, Wiegant J, Raap A, Hagemeijer A, Grosveld G (1992b): Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3′ half to different genes: Characterization of the set gene. Mol Cell Biol 12:3346-3355.
    • (1992) Mol Cell Biol , vol.12 , pp. 3346-3355
    • Von Lindern, M.1    Van Baal, S.2    Wiegant, J.3    Raap, A.4    Hagemeijer, A.5    Grosveld, G.6
  • 48
    • 0028233485 scopus 로고
    • NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure
    • Wente SR, Blobel G (1994): NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure. J Cell Biol 125:955-969.
    • (1994) J Cell Biol , vol.125 , pp. 955-969
    • Wente, S.R.1    Blobel, G.2
  • 49
    • 0026463881 scopus 로고
    • A new family of yeast nuclear pore complex proteins
    • Wente SR, Rout MP, Blobel G (1992): A new family of yeast nuclear pore complex proteins. J Cell Biol 119:705-723.
    • (1992) J Cell Biol , vol.119 , pp. 705-723
    • Wente, S.R.1    Rout, M.P.2    Blobel, G.3
  • 50
    • 0027744056 scopus 로고
    • Nup180, a novel nuclear pore complex protein localizing to the cytoplasmic ring and associated fibrils
    • Wilken N, Kossner U, Senecal JL, Scheer U, Dabauvalle MC (1993): Nup180, a novel nuclear pore complex protein localizing to the cytoplasmic ring and associated fibrils. J Cell Biol 123:1345-1354.
    • (1993) J Cell Biol , vol.123 , pp. 1345-1354
    • Wilken, N.1    Kossner, U.2    Senecal, J.L.3    Scheer, U.4    Dabauvalle, M.C.5
  • 51
    • 0027049622 scopus 로고
    • A new subclass of nucleoporins that functionally interact with nuclear pore protein NSP1
    • Wimmer C, Doye V, Grandi P, Nehrbass U, Hurt EC (1992): A new subclass of nucleoporins that functionally interact with nuclear pore protein NSP1. EMBO J 11:5051-5061.
    • (1992) EMBO J , vol.11 , pp. 5051-5061
    • Wimmer, C.1    Doye, V.2    Grandi, P.3    Nehrbass, U.4    Hurt, E.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.