Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery

Journal of Chemical Information and Modeling

Volumn 55, Issue 6, 2015, Pages 1181-1191

  Perry, Samuel R ^a   Xu, Weijun ^a   Wirija, Anna ^a   Lim, Junxian ^a   Yau, Mei Kwan ^a   Stoermer, Martin J ^a   Lucke, Andrew J ^a   Fairlie, David P ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALS; MODEL STRUCTURES; PROTEINS;

BOVINE RHODOPSIN; G-PROTEIN COUPLED RECEPTORS; POTENT COMPOUNDS; PROTEASE-ACTIVATED RECEPTOR 2; SEQUENCE HOMOLOGY; SIGNALING PATHWAYS; STRUCTURAL MODELS; VIRTUAL SCREENING;

LIGANDS;

LIGAND; PROTEINASE ACTIVATED RECEPTOR 2;

ANIMAL; ANTAGONISTS AND INHIBITORS; BINDING SITE; BOVINE; CELL MEMBRANE; CHEMISTRY; DRUG DEVELOPMENT; DRUG SCREENING; HT 29 CELL LINE; HUMAN; METABOLISM; MOLECULAR DOCKING; PROCEDURES; PROTEIN DATABASE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

ANIMALS; BINDING SITES; CATTLE; CELL MEMBRANE; DATABASES, PROTEIN; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HT29 CELLS; HUMANS; LIGANDS; MOLECULAR DOCKING SIMULATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, PAR-2; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84934911862     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/acs.jcim.5b00087     Document Type: Article

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