Antagonism of protease-activated receptor 2 protects against experimental colitis

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 2, 2012, Pages 256-265

  Lohman, Rink Jan ^a   Cotterell, Adam J ^a   Suen, Jacky ^a   Liu, Ligong ^a   Do, Anh T ^a   Vesey, David A ^a   Fairlie, David P ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CALCIUM; ENMD 1068; GASTROINTESTINAL AGENT; GB 88; INTERLEUKIN 6; MUCIN; MYELOPEROXIDASE; N1 3 METHYLBUTYRYL N4 6 AMINOHEXANOYLPIPERAZINE; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 2 ANTAGONIST; SALAZOSULFAPYRIDINE; TRINITROBENZENESULFONIC ACID; TRYPTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ABDOMINAL MASS; ACUTE COLITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BOWEL WALL THICKNESS; CALCIUM TRANSPORT; CHRONIC COLITIS; COLITIS; COLON OBSTRUCTION; COLON ULCER; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE COURSE; DISEASE MODEL; DRUG EFFICACY; DRUG POTENCY; DRUG TARGETING; EDEMA; ENZYME RELEASE; GOBLET CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERNALIZATION; INTESTINE CELL; INTESTINE WALL; MALE; MASTOCYTOSIS; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SINGLE DRUG DOSE; SYMPTOM; WEIGHT REDUCTION;

ANIMALS; BODY WEIGHT; CALCIUM SIGNALING; COLITIS; COLON; CYTOKINES; EDEMA; HT29 CELLS; HUMANS; INDENES; INTESTINAL MUCOSA; MALE; OLIGOPEPTIDES; PIPERAZINES; PIPERIDINES; RATS; RATS, WISTAR; RECEPTOR, PAR-2; SULFASALAZINE; SURVIVAL RATE; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TRINITROBENZENESULFONIC ACID; TRYPTASES; ULCER;

EID: 84862952456     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.187062     Document Type: Article

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