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Volumn 14, Issue , 2015, Pages 16-23

HIV-1 genotypic drug resistance testing: Digging deep, reaching wide?

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ANTIVIRUS AGENT;

EID: 84934909975     PISSN: 18796257     EISSN: 18796265     Source Type: Journal    
DOI: 10.1016/j.coviro.2015.06.001     Document Type: Review
Times cited : (37)

References (69)
  • 1
    • 73549084507 scopus 로고    scopus 로고
    • Clinical management of HIV-1 resistance
    • R. Paredes, and B. Clotet Clinical management of HIV-1 resistance Antiviral Res 85 2010 245 265
    • (2010) Antiviral Res , vol.85 , pp. 245-265
    • Paredes, R.1    Clotet, B.2
  • 7
    • 0033063294 scopus 로고    scopus 로고
    • Genetic polymorphism near HIV-1 reverse transcriptase resistance-associated codons is a major obstacle for the line probe assay as an alternative method to sequence analysis
    • N. Koch, N. Yahi, P. Colson, J. Fantini, and C. Tamalet Genetic polymorphism near HIV-1 reverse transcriptase resistance-associated codons is a major obstacle for the line probe assay as an alternative method to sequence analysis J Virol Methods 80 1999 25 31
    • (1999) J Virol Methods , vol.80 , pp. 25-31
    • Koch, N.1    Yahi, N.2    Colson, P.3    Fantini, J.4    Tamalet, C.5
  • 10
    • 77956667520 scopus 로고    scopus 로고
    • Covering all bases in HIV research: Unveiling a hidden world of viral evolution
    • B. Vrancken, S. Lequime, K. Theys, and P. Lemey Covering all bases in HIV research: unveiling a hidden world of viral evolution AIDS Rev 12 2010 89 102
    • (2010) AIDS Rev , vol.12 , pp. 89-102
    • Vrancken, B.1    Lequime, S.2    Theys, K.3    Lemey, P.4
  • 11
    • 84874964797 scopus 로고    scopus 로고
    • Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data
    • N. Beerenwinkel, H.F. Günthard, V. Roth, and K.J. Metzner Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data Front Microbiol 3 2012 329
    • (2012) Front Microbiol , vol.3 , pp. 329
    • Beerenwinkel, N.1    Günthard, H.F.2    Roth, V.3    Metzner, K.J.4
  • 13
    • 84927737704 scopus 로고    scopus 로고
    • Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis
    • Q.D. Pham, D.P. Wilson, M.G. Law, A.D. Kelleher, and L. Zhang Global burden of transmitted HIV drug resistance and HIV-exposure categories: a systematic review and meta-analysis AIDS 28 2014 2751 2762
    • (2014) AIDS , vol.28 , pp. 2751-2762
    • Pham, Q.D.1    Wilson, D.P.2    Law, M.G.3    Kelleher, A.D.4    Zhang, L.5
  • 14
    • 84934915200 scopus 로고    scopus 로고
    • Assessing the paradox between transmitted and acquired HIV type 1 drug resistance mutations in the Swiss HIV Cohort Study from 1998 to 2012
    • W.L. Yang, R. Kouyos, A.U. Scherrer, J. Böni, C. Shah, S. Yerly, T. Klimkait, V. Aubert, H. Furrer, and M. Battegay Assessing the paradox between transmitted and acquired HIV type 1 drug resistance mutations in the Swiss HIV Cohort Study from 1998 to 2012 J Infect Dis 212 2015 28 38
    • (2015) J Infect Dis , vol.212 , pp. 28-38
    • Yang, W.L.1    Kouyos, R.2    Scherrer, A.U.3    Böni, J.4    Shah, C.5    Yerly, S.6    Klimkait, T.7    Aubert, V.8    Furrer, H.9    Battegay, M.10
  • 15
    • 84867079060 scopus 로고    scopus 로고
    • Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: A global collaborative study and meta-regression analysis
    • R.K. Gupta, M.R. Jordan, B.J. Sultan, A. Hill, D.H. Davis, J. Gregson, A.W. Sawyer, R.L. Hamers, N. Ndembi, D. Pillay, and S. Bertagnolio Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis Lancet 380 2012 1250 1258
    • (2012) Lancet , vol.380 , pp. 1250-1258
    • Gupta, R.K.1    Jordan, M.R.2    Sultan, B.J.3    Hill, A.4    Davis, D.H.5    Gregson, J.6    Sawyer, A.W.7    Hamers, R.L.8    Ndembi, N.9    Pillay, D.10    Bertagnolio, S.11
  • 17
    • 84888391090 scopus 로고    scopus 로고
    • HIV-1 genetic variation and drug resistance development
    • S. Megens, and K. Van Laethem HIV-1 genetic variation and drug resistance development Expert Rev Anti Infect Ther 11 2013 1159 1178
    • (2013) Expert Rev Anti Infect Ther , vol.11 , pp. 1159-1178
    • Megens, S.1    Van Laethem, K.2
  • 18
    • 84867402808 scopus 로고    scopus 로고
    • The impact of HIV genetic polymorphisms and subtype differences on the occurrence of resistance to antiretroviral drugs
    • M.A. Wainberg, and B.G. Brenner The impact of HIV genetic polymorphisms and subtype differences on the occurrence of resistance to antiretroviral drugs Mol Biol Int 2012 2012 256982
    • (2012) Mol Biol Int , vol.2012 , pp. 256982
    • Wainberg, M.A.1    Brenner, B.G.2
  • 22
    • 84864944623 scopus 로고    scopus 로고
    • CIPRA-SA Project 1 Study Team: Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors
    • J.H. Brehm, D.L. Koontz, C.L. Wallis, K.A. Shutt, I. Sanne, R. Wood, J.A. McIntyre, W.S. Stevens, N. Sluis-Cremer, and J.W. Mellors CIPRA-SA Project 1 Study Team: frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors Clin Infect Dis 55 2012 737 745
    • (2012) Clin Infect Dis , vol.55 , pp. 737-745
    • Brehm, J.H.1    Koontz, D.L.2    Wallis, C.L.3    Shutt, K.A.4    Sanne, I.5    Wood, R.6    McIntyre, J.A.7    Stevens, W.S.8    Sluis-Cremer, N.9    Mellors, J.W.10
  • 23
    • 77958085720 scopus 로고    scopus 로고
    • Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120
    • A. Thielen, N. Sichtig, R. Kaiser, J. Lam, P.R. Harrigan, and T. Lengauer Improved prediction of HIV-1 coreceptor usage with sequence information from the second hypervariable loop of gp120 J Infect Dis 202 2010 1435 1443
    • (2010) J Infect Dis , vol.202 , pp. 1435-1443
    • Thielen, A.1    Sichtig, N.2    Kaiser, R.3    Lam, J.4    Harrigan, P.R.5    Lengauer, T.6
  • 24
    • 84864505786 scopus 로고    scopus 로고
    • Human immunodeficiency virus gag and protease: Partners in resistance
    • A. Fun, A.M. Wensing, J. Verheyen, and M. Nijhuis Human immunodeficiency virus gag and protease: partners in resistance Retrovirology 9 2012 63
    • (2012) Retrovirology , vol.9 , pp. 63
    • Fun, A.1    Wensing, A.M.2    Verheyen, J.3    Nijhuis, M.4
  • 27
    • 84929731273 scopus 로고    scopus 로고
    • A novel mutation, D404N, in the connection subdomain of reverse transcriptase of HIV-1 CRF08-BC subtype confers cross-resistance to NNRTIs
    • X.M. Zhang, H. Wu, Q. Zhang, T.C. Lau, H. Chu, Z.W. Chen, D.Y. Jin, and B.J. Zheng A novel mutation, D404N, in the connection subdomain of reverse transcriptase of HIV-1 CRF08-BC subtype confers cross-resistance to NNRTIs J Antimicrob Chemother 70 2015 1381 1390
    • (2015) J Antimicrob Chemother , vol.70 , pp. 1381-1390
    • Zhang, X.M.1    Wu, H.2    Zhang, Q.3    Lau, T.C.4    Chu, H.5    Chen, Z.W.6    Jin, D.Y.7    Zheng, B.J.8
  • 29
    • 84924275201 scopus 로고    scopus 로고
    • Cross-clade simultaneous HIV drug resistance genotyping for reverse transcriptase, protease, and integrase inhibitor mutations by Illumina MiSeq
    • D.M. Dudley, A.L. Bailey, S.H. Mehta, A.L. Hughes, G.D. Kirk, R.P. Westergaard, and D.H. O'Connor Cross-clade simultaneous HIV drug resistance genotyping for reverse transcriptase, protease, and integrase inhibitor mutations by Illumina MiSeq Retrovirology 11 2014 122
    • (2014) Retrovirology , vol.11 , pp. 122
    • Dudley, D.M.1    Bailey, A.L.2    Mehta, S.H.3    Hughes, A.L.4    Kirk, G.D.5    Westergaard, R.P.6    O'Connor, D.H.7
  • 31
    • 84896944940 scopus 로고    scopus 로고
    • Sensitive deep-sequencing-based HIV-1 genotyping assay to simultaneously determine susceptibility to protease, reverse transcriptase, integrase, and maturation inhibitors, as well as HIV-1 coreceptor tropism
    • R.M. Gibson, A.M. Meyer, D. Winner, J. Archer, F. Feyertag, E. Ruiz-Mateos, M. Leal, D.L. Robertson, C.L. Schmotzer, and M.E. Quiñones-Mateu Sensitive deep-sequencing-based HIV-1 genotyping assay to simultaneously determine susceptibility to protease, reverse transcriptase, integrase, and maturation inhibitors, as well as HIV-1 coreceptor tropism Antimicrob Agents Chemother 58 2014 2167 2185
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2167-2185
    • Gibson, R.M.1    Meyer, A.M.2    Winner, D.3    Archer, J.4    Feyertag, F.5    Ruiz-Mateos, E.6    Leal, M.7    Robertson, D.L.8    Schmotzer, C.L.9    Quiñones-Mateu, M.E.10
  • 32
    • 84903522789 scopus 로고    scopus 로고
    • "Deep" sequencing accuracy and reproducibility using Roche/454 technology for inferring co-receptor usage in HIV-1
    • D.J. Knapp, R.A. McGovern, A.F. Poon, X. Zhong, D. Chan, L.C. Swenson, W. Dong, and P.R. Harrigan "Deep" sequencing accuracy and reproducibility using Roche/454 technology for inferring co-receptor usage in HIV-1 PLoS One 9 2014 e99508
    • (2014) PLoS One , vol.9 , pp. e99508
    • Knapp, D.J.1    McGovern, R.A.2    Poon, A.F.3    Zhong, X.4    Chan, D.5    Swenson, L.C.6    Dong, W.7    Harrigan, P.R.8
  • 34
    • 77955690396 scopus 로고    scopus 로고
    • Minority variants of drug-resistant HIV
    • S. Gianella, and D.D. Richman Minority variants of drug-resistant HIV J Infect Dis 202 2010 657 666
    • (2010) J Infect Dis , vol.202 , pp. 657-666
    • Gianella, S.1    Richman, D.D.2
  • 35
    • 84886569625 scopus 로고    scopus 로고
    • Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay
    • G. Zhang, F. Cai, Z. Zhou, J. DeVos, N. Wagar, K. Diallo, I. Zulu, N. Wadonda-Kabondo, J.S. Stringer, and P.J. Weidle Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay J Clin Microbiol 51 2013 3666 3674
    • (2013) J Clin Microbiol , vol.51 , pp. 3666-3674
    • Zhang, G.1    Cai, F.2    Zhou, Z.3    Devos, J.4    Wagar, N.5    Diallo, K.6    Zulu, I.7    Wadonda-Kabondo, N.8    Stringer, J.S.9    Weidle, P.J.10
  • 39
    • 84908517801 scopus 로고    scopus 로고
    • Optimization of the oligonucleotide ligation assay for the detection of nevirapine resistance mutations in Zimbabwean human immunodeficiency virus type-1 subtype C
    • J. Mutsvangwa, I.A. Beck, L. Gwanzura, M.T. Manhanzva, L. Stranix-Chibanda, T. Chipato, and L.M. Frenkel Optimization of the oligonucleotide ligation assay for the detection of nevirapine resistance mutations in Zimbabwean human immunodeficiency virus type-1 subtype C J Virol Methods 210 2014 36 39
    • (2014) J Virol Methods , vol.210 , pp. 36-39
    • Mutsvangwa, J.1    Beck, I.A.2    Gwanzura, L.3    Manhanzva, M.T.4    Stranix-Chibanda, L.5    Chipato, T.6    Frenkel, L.M.7
  • 41
    • 48749086685 scopus 로고    scopus 로고
    • Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy
    • J.A. Johnson, J.F. Li, X. Wei, J. Lipscomb, D. Irlbeck, C. Craig, A. Smith, D.E. Bennett, M. Monsour, and P. Sandstrom Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy PLoS Med 5 2008 e158
    • (2008) PLoS Med , vol.5 , pp. e158
    • Johnson, J.A.1    Li, J.F.2    Wei, X.3    Lipscomb, J.4    Irlbeck, D.5    Craig, C.6    Smith, A.7    Bennett, D.E.8    Monsour, M.9    Sandstrom, P.10
  • 43
    • 67349096369 scopus 로고    scopus 로고
    • Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failure
    • M. Balduin, M. Oette, M.P. Däumer, D. Hoffmann, H.J. Pfister, and R. Kaiser Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failure J Clin Virol 45 2009 34 38
    • (2009) J Clin Virol , vol.45 , pp. 34-38
    • Balduin, M.1    Oette, M.2    Däumer, M.P.3    Hoffmann, D.4    Pfister, H.J.5    Kaiser, R.6
  • 46
    • 84865193368 scopus 로고    scopus 로고
    • Minority variants associated with resistance to HIV-1 nonnucleoside reverse transcriptase inhibitors during primary infection
    • F. Nicot, A. Saliou, S. Raymond, K. Sauné, M. Dubois, P. Massip, B. Marchou, P. Delobel, and J. Izopet Minority variants associated with resistance to HIV-1 nonnucleoside reverse transcriptase inhibitors during primary infection J Clin Virol 55 2012 107 113
    • (2012) J Clin Virol , vol.55 , pp. 107-113
    • Nicot, F.1    Saliou, A.2    Raymond, S.3    Sauné, K.4    Dubois, M.5    Massip, P.6    Marchou, B.7    Delobel, P.8    Izopet, J.9
  • 47
    • 84892718136 scopus 로고    scopus 로고
    • Highly-sensitive allele-specific PCR testing identifies a greater prevalence of transmitted HIV drug resistance in Japan
    • M. Nishizawa, J. Hattori, T. Shiino, T. Matano, W. Heneine, J.A. Johnson, and W. Sugiura Highly-sensitive allele-specific PCR testing identifies a greater prevalence of transmitted HIV drug resistance in Japan PLoS One 8 2013 e83150
    • (2013) PLoS One , vol.8 , pp. e83150
    • Nishizawa, M.1    Hattori, J.2    Shiino, T.3    Matano, T.4    Heneine, W.5    Johnson, J.A.6    Sugiura, W.7
  • 48
    • 84922481959 scopus 로고    scopus 로고
    • Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failure
    • S. Mohamed, G. Penaranda, D. Gonzalez, C. Camus, H. Khiri, R. Boulmé, C. Sayada, P. Philibert, D. Olive, and P. Halfon Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failure AIDS 28 2014 1315 1324
    • (2014) AIDS , vol.28 , pp. 1315-1324
    • Mohamed, S.1    Penaranda, G.2    Gonzalez, D.3    Camus, C.4    Khiri, H.5    Boulmé, R.6    Sayada, C.7    Philibert, P.8    Olive, D.9    Halfon, P.10
  • 50
    • 76449107778 scopus 로고    scopus 로고
    • Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment-experienced patients
    • E.K. Halvas, A. Wiegand, V.F. Boltz, M. Kearney, D. Nissley, M. Wantman, S.M. Hammer, S. Palmer, F. Vaida, J.M. Coffin, and J.W. Mellors Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment-experienced patients J Infect Dis 201 2010 672 680
    • (2010) J Infect Dis , vol.201 , pp. 672-680
    • Halvas, E.K.1    Wiegand, A.2    Boltz, V.F.3    Kearney, M.4    Nissley, D.5    Wantman, M.6    Hammer, S.M.7    Palmer, S.8    Vaida, F.9    Coffin, J.M.10    Mellors, J.W.11
  • 51
    • 84894259565 scopus 로고    scopus 로고
    • Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP
    • V.F. Boltz, Y. Bao, S. Lockman, E.K. Halvas, M.F. Kearney, J.A. McIntyre, R.T. Schooley, M.D. Hughes, J.M. Coffin, J.W. Mellors, and OCTANE/A5208 Team Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP J Infect Dis 209 2014 703 710
    • (2014) J Infect Dis , vol.209 , pp. 703-710
    • Boltz, V.F.1    Bao, Y.2    Lockman, S.3    Halvas, E.K.4    Kearney, M.F.5    McIntyre, J.A.6    Schooley, R.T.7    Hughes, M.D.8    Coffin, J.M.9    Mellors, J.W.10    Team, O.11
  • 52
    • 33847034809 scopus 로고    scopus 로고
    • Persistence of K103N-containing HIV-1 variants after single-dose nevirapine for prevention of HIV-1 mother-to-child transmission
    • T.S. Flys, D. Donnell, A. Mwatha, C. Nakabiito, P. Musoke, F. Mmiro, J.B. Jackson, L.A. Guay, and S.H. Eshleman Persistence of K103N-containing HIV-1 variants after single-dose nevirapine for prevention of HIV-1 mother-to-child transmission J Infect Dis 195 2007 711 715
    • (2007) J Infect Dis , vol.195 , pp. 711-715
    • Flys, T.S.1    Donnell, D.2    Mwatha, A.3    Nakabiito, C.4    Musoke, P.5    Mmiro, F.6    Jackson, J.B.7    Guay, L.A.8    Eshleman, S.H.9
  • 53
    • 79959598119 scopus 로고    scopus 로고
    • Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure
    • P. Delobel, A. Saliou, F. Nicot, M. Dubois, S. Trancart, P. Tangre, J.P. Aboulker, A.M. Taburet, J.M. Molina, and P. Massip Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure PLoS One 6 2011 e21655
    • (2011) PLoS One , vol.6 , pp. e21655
    • Delobel, P.1    Saliou, A.2    Nicot, F.3    Dubois, M.4    Trancart, S.5    Tangre, P.6    Aboulker, J.P.7    Taburet, A.M.8    Molina, J.M.9    Massip, P.10
  • 58
    • 84896443660 scopus 로고    scopus 로고
    • Sensitive testing of plasma HIV-1 RNA and Sanger sequencing of cellular HIV-1 DNA for the detection of drug resistance prior to starting first-line antiretroviral therapy with etravirine or efavirenz
    • A.M. Geretti, T. Conibear, A. Hill, J.A. Johnson, L. Tambuyzer, K. Thys, J. Vingerhoets, Y. Van Delft, and SENSE Study Group Sensitive testing of plasma HIV-1 RNA and Sanger sequencing of cellular HIV-1 DNA for the detection of drug resistance prior to starting first-line antiretroviral therapy with etravirine or efavirenz J Antimicrob Chemother 69 2014 1090 1097
    • (2014) J Antimicrob Chemother , vol.69 , pp. 1090-1097
    • Geretti, A.M.1    Conibear, T.2    Hill, A.3    Johnson, J.A.4    Tambuyzer, L.5    Thys, K.6    Vingerhoets, J.7    Van Delft, Y.8    Study Group, S.9
  • 59
    • 79955477986 scopus 로고    scopus 로고
    • Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): A European multicohort study
    • L. Wittkop, H.F. Günthard, F. de Wolf, D. Dunn, A. Cozzi-Lepri, A. de Luca, C. Kücherer, N. Obel, V. von Wyl, and B. Masquelier Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study Lancet Infect Dis 11 2011 363 371
    • (2011) Lancet Infect Dis , vol.11 , pp. 363-371
    • Wittkop, L.1    Günthard, H.F.2    De Wolf, F.3    Dunn, D.4    Cozzi-Lepri, A.5    De Luca, A.6    Kücherer, C.7    Obel, N.8    Von Wyl, V.9    Masquelier, B.10
  • 61
    • 79851502517 scopus 로고    scopus 로고
    • Deep sequencing to infer HIV-1 co-receptor usage: Application to three clinical trials of maraviroc in treatment-experienced patients
    • L.C. Swenson, T. Mo, W.W. Dong, X. Zhong, C.K. Woods, M.A. Jensen, A. Thielen, D. Chapman, M. Lewis, and I. James Deep sequencing to infer HIV-1 co-receptor usage: application to three clinical trials of maraviroc in treatment-experienced patients J Infect Dis 203 2011 237 245
    • (2011) J Infect Dis , vol.203 , pp. 237-245
    • Swenson, L.C.1    Mo, T.2    Dong, W.W.3    Zhong, X.4    Woods, C.K.5    Jensen, M.A.6    Thielen, A.7    Chapman, D.8    Lewis, M.9    James, I.10
  • 66
    • 0036616384 scopus 로고    scopus 로고
    • A genotypic drug resistance interpretation algorithm that significantly predicts therapy response in HIV-1-infected patients
    • K. Van Laethem, A. De Luca, A. Antinori, A. Cingolani, C.F. Perna, and A.M. Vandamme A genotypic drug resistance interpretation algorithm that significantly predicts therapy response in HIV-1-infected patients Antivir Ther 7 2002 123 129
    • (2002) Antivir Ther , vol.7 , pp. 123-129
    • Van Laethem, K.1    De Luca, A.2    Antinori, A.3    Cingolani, A.4    Perna, C.F.5    Vandamme, A.M.6
  • 67
  • 68
    • 84875676262 scopus 로고    scopus 로고
    • Pre-existing mutations in the rilpivirine phase III trials ECHO and THRIVE: Prevalence and impact on virological response
    • J. Vingerhoets, L. Rimsky, V. Van Eygen, S. Nijs, S. Vanveggel, K. Boven, and G. Picchio Pre-existing mutations in the rilpivirine phase III trials ECHO and THRIVE: prevalence and impact on virological response Antivir Ther 18 2013 253 256
    • (2013) Antivir Ther , vol.18 , pp. 253-256
    • Vingerhoets, J.1    Rimsky, L.2    Van Eygen, V.3    Nijs, S.4    Vanveggel, S.5    Boven, K.6    Picchio, G.7
  • 69
    • 84922481959 scopus 로고    scopus 로고
    • Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failure
    • S. Mohamed, G. Penaranda, D. Gonzalez, C. Camus, H. Khiri, R. Boulmé, C. Sayada, P. Philibert, D. Olive, and P. Halfon Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failure AIDS 28 2014 1315 1324
    • (2014) AIDS , vol.28 , pp. 1315-1324
    • Mohamed, S.1    Penaranda, G.2    Gonzalez, D.3    Camus, C.4    Khiri, H.5    Boulmé, R.6    Sayada, C.7    Philibert, P.8    Olive, D.9    Halfon, P.10


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