Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Delobel, Pierre ^a,b   Saliou, Adrien ^b   Nicot, Florence ^a,b   Dubois, Martine ^a,b   Trancart, Stéphanie ^a   Tangre, Philippe ^c   Aboulker, Jean Pierre ^c   Taburet, Anne Marie ^d   Molina, Jean Michel ^e   Massip, Patrice ^a   Marchou, Bruno ^a   Izopet, Jacques ^a,b  

^a CHU PURPAN   (France)

^b University of Toulouse III   (France)

^c INSERM   (France)

^d BICÊTRE HOSPITAL   (France)

^e SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EFAVIRENZ; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZOXAZINE DERIVATIVE; POL PROTEIN;

ADULT; ALLELE; ANTIVIRAL RESISTANCE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG RESPONSE; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; FEMALE; GENE FREQUENCY; GENETIC SELECTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INTERMETHOD COMPARISON; LONGITUDINAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; PREDICTION; PYROSEQUENCING; REAL TIME POLYMERASE CHAIN REACTION; VIRUS LOAD; VIRUS MUTATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; GENETICS; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ADULT; ANTI-HIV AGENTS; BENZOXAZINES; DRUG RESISTANCE, VIRAL; FEMALE; HIV-1; HUMANS; MALE; MIDDLE AGED; POL GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; REAL-TIME POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 79959598119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021655     Document Type: Article

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