Improved detection of resistance at failure to a tenofovir, emtricitabine and efavirenz regimen by ultradeep sequencing

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 5, 2014, Pages 1503-1506

  Todesco, Eve ^a,c   Rodriguez, Christophe ^d,e   Morand Joubert, Laurence ^a,b,f   Mercier Darty, Mélanie ^d   Desire, Nathalie ^a,c   Wirden, Marc ^a,c   Girard, Pierre Marie ^a,b,f   Katlama, Christine ^a,b,c   Calvez, Vincent ^a,c   Marcelin, Anne Geneviève ^a,c  

^a SORBONNE UNIVERSITÉ   (France)

^b INSTITUT PIERRE LOUIS D EPIDÉMIOLOGIE ET DE SANTÉ PUBLIQUE   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d HENRI MONDOR HOSPITAL   (France)

^e INSERM U955   (France)

^f HÔPITAL SAINT ANTOINE   (France)

Author keywords

HIV 1 drug resistance; Minority variants; Resistance genotyping; Virological failure

Indexed keywords

EFAVIRENZ; EMTRICITABINE; TENOFOVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZOXAZINE DERIVATIVE;

ANTIVIRAL RESISTANCE; ARTICLE; CD4 LYMPHOCYTE COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG TREATMENT FAILURE; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 SUBTYPE B; NEXT GENERATION SEQUENCING; SANGER SEQUENCING; ULTRADEEP SEQUENCING; VIRUS LOAD; VIRUS MUTATION; DRUG EFFECTS; GENETICS; GENOTYPING TECHNIQUE; HIGH THROUGHPUT SEQUENCING; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS; MICROBIAL SENSITIVITY TEST; PLASMA; PROCEDURES; TREATMENT FAILURE; VIROLOGY;

ANTI-HIV AGENTS; BENZOXAZINES; DRUG RESISTANCE, VIRAL; EMTRICITABINE; GENOTYPING TECHNIQUES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HIV; HIV INFECTIONS; HUMANS; MICROBIAL SENSITIVITY TESTS; PLASMA; TENOFOVIR; TREATMENT FAILURE;

EID: 84929732555     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku557     Document Type: Article

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