메뉴 건너뛰기




Volumn 116, Issue , 2015, Pages 52-60

α-Lipoic acid attenuates LPS-induced liver injury by improving mitochondrial function in association with GR mitochondrial DNA occupancy

Author keywords

LA; Liver protective; LPS; Mice; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GLUCOCORTICOID RECEPTOR; LIPOPOLYSACCHARIDE; MITOCHONDRIAL COMPLEX IV; MITOCHONDRIAL COMPLEX V; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SIRTUIN 3; THIOCTIC ACID; UNCLASSIFIED DRUG; TUMOR NECROSIS FACTOR ALPHA;

EID: 84934758687     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2015.06.023     Document Type: Article
Times cited : (21)

References (48)
  • 1
    • 84879252953 scopus 로고    scopus 로고
    • 2-phenylethynesulfonamide prevents induction of pro-inflammatory factors and attenuates LPS-induced liver injury by targeting NHE1-Hsp70 complex in mice
    • C. Huang, J. Wang, Z. Chen, Y. Wang, and W. Zhang 2-phenylethynesulfonamide prevents induction of pro-inflammatory factors and attenuates LPS-induced liver injury by targeting NHE1-Hsp70 complex in mice PloS One 8 2013 e67582
    • (2013) PloS One , vol.8
    • Huang, C.1    Wang, J.2    Chen, Z.3    Wang, Y.4    Zhang, W.5
  • 2
    • 84882827495 scopus 로고    scopus 로고
    • Decoding cell death signals in liver inflammation
    • C. Brenner, L. Galluzzi, O. Kepp, and G. Kroemer Decoding cell death signals in liver inflammation J. Hepatol. 59 2013 583 594
    • (2013) J. Hepatol. , vol.59 , pp. 583-594
    • Brenner, C.1    Galluzzi, L.2    Kepp, O.3    Kroemer, G.4
  • 4
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • G. Kroemer, L. Galluzzi, and C. Brenner Mitochondrial membrane permeabilization in cell death Physiol. Rev. 87 2007 99 163
    • (2007) Physiol. Rev. , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 5
    • 10644277053 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in liver disease and organ transplantation
    • T. Hassanein, and T. Frederick Mitochondrial dysfunction in liver disease and organ transplantation Mitochondrion 4 2004 609 620
    • (2004) Mitochondrion , vol.4 , pp. 609-620
    • Hassanein, T.1    Frederick, T.2
  • 10
    • 84905466322 scopus 로고    scopus 로고
    • Role of alpha-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis
    • X. Xia, C. Su, J. Fu, P. Zhang, X. Jiang, D. Xu, L. Hu, E. Song, and Y. Song Role of alpha-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis Int. Immunopharmacol. 22 2014 293 302
    • (2014) Int. Immunopharmacol. , vol.22 , pp. 293-302
    • Xia, X.1    Su, C.2    Fu, J.3    Zhang, P.4    Jiang, X.5    Xu, D.6    Hu, L.7    Song, E.8    Song, Y.9
  • 12
    • 34547885436 scopus 로고    scopus 로고
    • Glucocorticoids, metabolism and metabolic diseases
    • A. Vegiopoulos, and S. Herzig Glucocorticoids, metabolism and metabolic diseases Mol. Cell. Endocrinol. 275 2007 43 61
    • (2007) Mol. Cell. Endocrinol. , vol.275 , pp. 43-61
    • Vegiopoulos, A.1    Herzig, S.2
  • 14
    • 70349276663 scopus 로고    scopus 로고
    • Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide
    • N. Hirasawa, K. Yashima, and K. Ishihara Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide Life Sci. 85 2009 578 585
    • (2009) Life Sci. , vol.85 , pp. 578-585
    • Hirasawa, N.1    Yashima, K.2    Ishihara, K.3
  • 16
    • 84871981752 scopus 로고    scopus 로고
    • Endothelial glucocorticoid receptor is required for protection against sepsis
    • J.E. Goodwin, Y. Feng, H. Velazquez, and W.C. Sessa Endothelial glucocorticoid receptor is required for protection against sepsis Proc. Natl. Acad. Sci. U S A. 110 2013 306 311
    • (2013) Proc. Natl. Acad. Sci. U S A. , vol.110 , pp. 306-311
    • Goodwin, J.E.1    Feng, Y.2    Velazquez, H.3    Sessa, W.C.4
  • 17
    • 84887026103 scopus 로고    scopus 로고
    • Expression of the glucocorticoid receptor is decreased in experimental Staphylococcus aureus sepsis
    • M. Bergquist, M. Nurkkala, C. Rylander, E. Kristiansson, G. Hedenstierna, and C. Lindholm Expression of the glucocorticoid receptor is decreased in experimental Staphylococcus aureus sepsis J. Infect. 67 2013 574 583
    • (2013) J. Infect. , vol.67 , pp. 574-583
    • Bergquist, M.1    Nurkkala, M.2    Rylander, C.3    Kristiansson, E.4    Hedenstierna, G.5    Lindholm, C.6
  • 18
    • 84876685693 scopus 로고    scopus 로고
    • Glucocorticoid receptor is involved in the breed-dependent transcriptional regulation of mtDNA- and nuclear-encoded mitochondria genes in the liver of newborn piglets
    • R. Li, H. Zou, Y. Jia, and R. Zhao Glucocorticoid receptor is involved in the breed-dependent transcriptional regulation of mtDNA- and nuclear-encoded mitochondria genes in the liver of newborn piglets BMC Vet. Res. 9 2013 87
    • (2013) BMC Vet. Res. , vol.9 , pp. 87
    • Li, R.1    Zou, H.2    Jia, Y.3    Zhao, R.4
  • 19
    • 84877765895 scopus 로고    scopus 로고
    • Maternal low-protein diet affects epigenetic regulation of hepatic mitochondrial DNA transcription in a sex-specific manner in newborn piglets associated with GR binding to its promoter
    • Y. Jia, R. Li, R. Cong, X. Yang, Q. Sun, N. Parvizi, and R. Zhao Maternal low-protein diet affects epigenetic regulation of hepatic mitochondrial DNA transcription in a sex-specific manner in newborn piglets associated with GR binding to its promoter PloS One 8 2013 e63855
    • (2013) PloS One , vol.8
    • Jia, Y.1    Li, R.2    Cong, R.3    Yang, X.4    Sun, Q.5    Parvizi, N.6    Zhao, R.7
  • 21
    • 73949133993 scopus 로고    scopus 로고
    • The molecular basis of the host response to lipopolysaccharide, Nature reviews
    • C.E. Bryant, D.R. Spring, M. Gangloff, and N.J. Gay The molecular basis of the host response to lipopolysaccharide, Nature reviews Microbiology 8 2010 8 14
    • (2010) Microbiology , vol.8 , pp. 8-14
    • Bryant, C.E.1    Spring, D.R.2    Gangloff, M.3    Gay, N.J.4
  • 23
    • 0017157711 scopus 로고
    • Probes of initial phosphorylation events in ATP synthesis by chloroplasts
    • D.J. Smith, B.O. Stokes, and P.D. Boyer Probes of initial phosphorylation events in ATP synthesis by chloroplasts J. Biol. Chem. 251 1976 4165 4171
    • (1976) J. Biol. Chem. , vol.251 , pp. 4165-4171
    • Smith, D.J.1    Stokes, B.O.2    Boyer, P.D.3
  • 24
    • 34347236921 scopus 로고    scopus 로고
    • Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts
    • C. Frezza, S. Cipolat, and L. Scorrano Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts Nat. Protoc. 2 2007 287 295
    • (2007) Nat. Protoc. , vol.2 , pp. 287-295
    • Frezza, C.1    Cipolat, S.2    Scorrano, L.3
  • 25
    • 33749865859 scopus 로고    scopus 로고
    • Nuclear and mitochondrial genome responses in HeLa cells treated with inhibitors of mitochondrial DNA expression
    • J. Piechota, R. Szczesny, K. Wolanin, A. Chlebowski, and E. Bartnik Nuclear and mitochondrial genome responses in HeLa cells treated with inhibitors of mitochondrial DNA expression Acta Biochim. Pol. 53 2006 485 495
    • (2006) Acta Biochim. Pol. , vol.53 , pp. 485-495
    • Piechota, J.1    Szczesny, R.2    Wolanin, K.3    Chlebowski, A.4    Bartnik, E.5
  • 26
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods (San Diego Calif.) 25 2001 402 408
    • (2001) Methods (San Diego Calif.) , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 27
    • 84869084013 scopus 로고    scopus 로고
    • Maternal low-protein diet causes epigenetic deregulation of HMGCR and CYP7alpha1 in the liver of weaning piglets
    • R. Cong, Y. Jia, R. Li, Y. Ni, X. Yang, Q. Sun, N. Parvizi, and R. Zhao Maternal low-protein diet causes epigenetic deregulation of HMGCR and CYP7alpha1 in the liver of weaning piglets J. Nutr. Biochem. 23 2012 1647 1654
    • (2012) J. Nutr. Biochem. , vol.23 , pp. 1647-1654
    • Cong, R.1    Jia, Y.2    Li, R.3    Ni, Y.4    Yang, X.5    Sun, Q.6    Parvizi, N.7    Zhao, R.8
  • 28
    • 79960145205 scopus 로고    scopus 로고
    • Maternal dietary protein affects transcriptional regulation of myostatin gene distinctively at weaning and finishing stages in skeletal muscle of Meishan pigs
    • X. Liu, J. Wang, R. Li, X. Yang, Q. Sun, E. Albrecht, and R. Zhao Maternal dietary protein affects transcriptional regulation of myostatin gene distinctively at weaning and finishing stages in skeletal muscle of Meishan pigs Epigenetics Off. J. DNA Methylation Soc. 6 2011 899 907
    • (2011) Epigenetics Off. J. DNA Methylation Soc. , vol.6 , pp. 899-907
    • Liu, X.1    Wang, J.2    Li, R.3    Yang, X.4    Sun, Q.5    Albrecht, E.6    Zhao, R.7
  • 29
    • 0036081598 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance, American journal of physiology
    • H. Sugita, M. Kaneki, E. Tokunaga, M. Sugita, C. Koike, S. Yasuhara, R.G. Tompkins, and J.A. Martyn Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance, American journal of physiology Endocrinol. Metabol. 282 2002 E386 E394
    • (2002) Endocrinol. Metabol. , vol.282 , pp. E386-E394
    • Sugita, H.1    Kaneki, M.2    Tokunaga, E.3    Sugita, M.4    Koike, C.5    Yasuhara, S.6    Tompkins, R.G.7    Martyn, J.A.8
  • 31
    • 84891693360 scopus 로고    scopus 로고
    • Lipoic acid prevents fructose-induced changes in liver carbohydrate metabolism: role of oxidative stress
    • M.C. Castro, F. Francini, J.J. Gagliardino, and M.L. Massa Lipoic acid prevents fructose-induced changes in liver carbohydrate metabolism: role of oxidative stress Biochim. Biophys. Acta 1840 2014 1145 1151
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 1145-1151
    • Castro, M.C.1    Francini, F.2    Gagliardino, J.J.3    Massa, M.L.4
  • 32
    • 34247220265 scopus 로고    scopus 로고
    • Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway
    • W.J. Zhang, H. Wei, T. Hagen, and B. Frei Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway Proc. Natl. Acad. Sci. U S A. 104 2007 4077 4082
    • (2007) Proc. Natl. Acad. Sci. U S A. , vol.104 , pp. 4077-4082
    • Zhang, W.J.1    Wei, H.2    Hagen, T.3    Frei, B.4
  • 33
    • 84879499444 scopus 로고    scopus 로고
    • Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells
    • J. Wei, M. Liu, H. Liu, H. Wang, F. Wang, Y. Zhang, L. Han, and X. Lin Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells J. Appl. Toxicol. JAT 33 2013 756 765
    • (2013) J. Appl. Toxicol. JAT , vol.33 , pp. 756-765
    • Wei, J.1    Liu, M.2    Liu, H.3    Wang, H.4    Wang, F.5    Zhang, Y.6    Han, L.7    Lin, X.8
  • 35
    • 33646716659 scopus 로고    scopus 로고
    • The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria
    • L. Kussmaul, and J. Hirst The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria Proc. Natl. Acad. Sci. U S A. 103 2006 7607 7612
    • (2006) Proc. Natl. Acad. Sci. U S A. , vol.103 , pp. 7607-7612
    • Kussmaul, L.1    Hirst, J.2
  • 36
    • 84929702344 scopus 로고    scopus 로고
    • The effect of aspartate on the energy metabolism in the liver of weanling pigs challenged with lipopolysaccharide
    • P. Kang, Y. Liu, H. Zhu, S. Li, H. Shi, F. Chen, W. Leng, D. Pi, Y. Hou, and D. Yi The effect of aspartate on the energy metabolism in the liver of weanling pigs challenged with lipopolysaccharide Eur. J. Nutr. 54 2015 581 588
    • (2015) Eur. J. Nutr. , vol.54 , pp. 581-588
    • Kang, P.1    Liu, Y.2    Zhu, H.3    Li, S.4    Shi, H.5    Chen, F.6    Leng, W.7    Pi, D.8    Hou, Y.9    Yi, D.10
  • 37
    • 70350370459 scopus 로고    scopus 로고
    • Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm
    • K.R. Feingold, A. Moser, S.M. Patzek, J.K. Shigenaga, and C. Grunfeld Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm J. Lipid Res. 50 2009 2055 2063
    • (2009) J. Lipid Res. , vol.50 , pp. 2055-2063
    • Feingold, K.R.1    Moser, A.2    Patzek, S.M.3    Shigenaga, J.K.4    Grunfeld, C.5
  • 38
  • 40
    • 77955347446 scopus 로고    scopus 로고
    • Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
    • X. Kong, R. Wang, Y. Xue, X. Liu, H. Zhang, Y. Chen, F. Fang, and Y. Chang Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis PloS One 5 2010 e11707
    • (2010) PloS One , vol.5
    • Kong, X.1    Wang, R.2    Xue, Y.3    Liu, X.4    Zhang, H.5    Chen, Y.6    Fang, F.7    Chang, Y.8
  • 41
    • 79958041601 scopus 로고    scopus 로고
    • The SirT3 divining rod points to oxidative stress
    • E.L. Bell, and L. Guarente The SirT3 divining rod points to oxidative stress Mol. Cell. 42 2011 561 568
    • (2011) Mol. Cell. , vol.42 , pp. 561-568
    • Bell, E.L.1    Guarente, L.2
  • 42
    • 67949102053 scopus 로고    scopus 로고
    • Recent progress in the biology and physiology of sirtuins
    • T. Finkel, C.X. Deng, and R. Mostoslavsky Recent progress in the biology and physiology of sirtuins Nature 460 2009 587 591
    • (2009) Nature , vol.460 , pp. 587-591
    • Finkel, T.1    Deng, C.X.2    Mostoslavsky, R.3
  • 44
    • 75349111140 scopus 로고    scopus 로고
    • Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
    • H. Cimen, M.J. Han, Y. Yang, Q. Tong, H. Koc, and E.C. Koc Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria Biochemistry 49 2010 304 311
    • (2010) Biochemistry , vol.49 , pp. 304-311
    • Cimen, H.1    Han, M.J.2    Yang, Y.3    Tong, Q.4    Koc, H.5    Koc, E.C.6
  • 46
    • 78349243997 scopus 로고    scopus 로고
    • Advances in genome-wide DNA methylation analysis
    • R. Gupta, A. Nagarajan, and N. Wajapeyee Advances in genome-wide DNA methylation analysis BioTechniques 49 2010 iii-xi
    • (2010) BioTechniques , vol.49 , pp. iii-xi
    • Gupta, R.1    Nagarajan, A.2    Wajapeyee, N.3
  • 47
    • 79952749156 scopus 로고    scopus 로고
    • DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
    • L.S. Shock, P.V. Thakkar, E.J. Peterson, R.G. Moran, and S.M. Taylor DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria Proc. Natl. Acad. Sci. U S A. 108 2011 3630 3635
    • (2011) Proc. Natl. Acad. Sci. U S A. , vol.108 , pp. 3630-3635
    • Shock, L.S.1    Thakkar, P.V.2    Peterson, E.J.3    Moran, R.G.4    Taylor, S.M.5
  • 48
    • 80051792747 scopus 로고    scopus 로고
    • Glucocorticoids induce mitochondrial gene transcription in HepG2 cells: role of the mitochondrial glucocorticoid receptor
    • A.M. Psarra, and C.E. Sekeris Glucocorticoids induce mitochondrial gene transcription in HepG2 cells: role of the mitochondrial glucocorticoid receptor Biochim. Biophys. Acta 1813 2011 1814 1821
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1814-1821
    • Psarra, A.M.1    Sekeris, C.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.