Prefibrillar huntingtin oligomers isolated from HD brain potently seed amyloid formation

FEBS Letters

Volumn 589, Issue 15, 2015, Pages 1897-1903

  Morozova, Olga A ^a   Gupta, Sharad ^a,b   Colby, David W ^a  

^a UNIVERSITY OF DELAWARE   (United States)

^b INDIAN INSTITUTE OF TECHNOLOGY GANDHINAGAR   (India)

Author keywords

Amyloid; Huntington's disease; Neurodegeneration; Oligomer; Polyglutamine; Protein misfolding

Indexed keywords

AMYLOID; HUNTINGTIN; OLIGOMER; POLYGLUTAMINE; BIOPOLYMER; HTT PROTEIN, HUMAN; NERVE PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MISFOLDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; ANIMAL; BIOSYNTHESIS; BRAIN; DISEASE MODEL; ISOLATION AND PURIFICATION; METABOLISM;

AMYLOID; ANIMALS; BIOPOLYMERS; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; HUNTINGTON DISEASE; MICE; NERVE TISSUE PROTEINS;

EID: 84934442982     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.05.041     Document Type: Article

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