메뉴 건너뛰기




Volumn 824, Issue , 2014, Pages 209-219

The chemokine (C-C Motif) ligand 2 in neuroinflammation and neurodegeneration

Author keywords

Alzheimer's disease; CCL2; MCP 1; Multiple sclerosis; Neurodegeneration; Neuroinflammation; Parkinson's disease; Stroke

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN 1;

EID: 84934441661     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-7320-0_15     Document Type: Review
Times cited : (14)

References (91)
  • 1
    • 0024538514 scopus 로고
    • Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants
    • Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ. Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med. 1989;169(4):1449-59.
    • (1989) J Exp Med. , vol.169 , Issue.4 , pp. 1449-1459
    • Yoshimura, T.1    Robinson, E.A.2    Tanaka, S.3    Appella, E.4    Kuratsu, J.5    Leonard, E.J.6
  • 2
  • 3
    • 22644444838 scopus 로고    scopus 로고
    • Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: Evidence for its colocalization with neurotransmitters and neuropeptides
    • Banisadr G, Gosselin RD, Mechighel P, Kitabgi P, Rostene W, Parsadaniantz SM. Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: evidence for its colocalization with neurotransmitters and neuropeptides. J Comp Neurol. 2005;489(3):275-92.
    • (2005) J Comp Neurol. , vol.489 , Issue.3 , pp. 275-292
    • Banisadr, G.1    Gosselin, R.D.2    Mechighel, P.3    Kitabgi, P.4    Rostene, W.5    Parsadaniantz, S.M.6
  • 4
    • 26644458316 scopus 로고    scopus 로고
    • Constitutive neuronal expression of CCR2 chemokine receptor and its colocalization with neurotransmitters in normal rat brain: Functional effect of MCP-1/CCL2 on calcium mobilization in primary cultured neurons
    • Banisadr G, Gosselin RD, Mechighel P, Rostene W, Kitabgi P, Melik PS. Constitutive neuronal expression of CCR2 chemokine receptor and its colocalization with neurotransmitters in normal rat brain: functional effect of MCP-1/CCL2 on calcium mobilization in primary cultured neurons. J Comp Neurol. 2005;492(2):178-92.
    • (2005) J Comp Neurol. , vol.492 , Issue.2 , pp. 178-192
    • Banisadr, G.1    Gosselin, R.D.2    Mechighel, P.3    Rostene, W.4    Kitabgi, P.5    Melik, P.S.6
  • 6
    • 18344407347 scopus 로고    scopus 로고
    • Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons
    • Coughlan CM, McManus CM, Sharron M, Gao Z, Murphy D, Jaffer S, et al. Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Neuroscience. 2000;97(3):591-600.
    • (2000) Neuroscience. , vol.97 , Issue.3 , pp. 591-600
    • Coughlan, C.M.1    McManus, C.M.2    Sharron, M.3    Gao, Z.4    Murphy, D.5    Jaffer, S.6
  • 8
    • 28244464861 scopus 로고    scopus 로고
    • Constitutive expression of CCR2 chemokine receptor and inhibition by MCP-1/ CCL2 of GABA-induced currents in spinal cord neurones
    • Gosselin RD, Varela C, Banisadr G, Mechighel P, Rostene W, Kitabgi P, et al. Constitutive expression of CCR2 chemokine receptor and inhibition by MCP-1/ CCL2 of GABA-induced currents in spinal cord neurones. J Neurochem. 2005;95(4):1023-34.
    • (2005) J Neurochem. , vol.95 , Issue.4 , pp. 1023-1034
    • Gosselin, R.D.1    Varela, C.2    Banisadr, G.3    Mechighel, P.4    Rostene, W.5    Kitabgi, P.6
  • 9
    • 0242273334 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein- 1 (CCL2) in inflammatory disease and adaptive immunity: Therapeutic opportunities and controversies
    • Daly C, Rollins BJ. Monocyte chemoattractant protein- 1 (CCL2) in inflammatory disease and adaptive immunity: therapeutic opportunities and controversies. Microcirculation. 2003;10(3-4):247-57.
    • (2003) Microcirculation. , vol.10 , Issue.3-4 , pp. 247-257
    • Daly, C.1    Rollins, B.J.2
  • 10
    • 66949146836 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein- 1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease
    • Sokolova A, Hill MD, Rahimi F, Warden LA, Halliday GM, Shepherd CE. Monocyte chemoattractant protein- 1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease. Brain Pathol. 2009;19(3):392-8.
    • (2009) Brain Pathol. , vol.19 , Issue.3 , pp. 392-398
    • Sokolova, A.1    Hill, M.D.2    Rahimi, F.3    Warden, L.A.4    Halliday, G.M.5    Shepherd, C.E.6
  • 12
    • 84875369325 scopus 로고    scopus 로고
    • Systemic immune system alterations in early stages of Alzheimer's disease
    • Zhang R, Miller RG, Madison C, Jin X, Honrada R, Harris W, et al. Systemic immune system alterations in early stages of Alzheimer's disease. J Neuroimmunol. 2013;256(1-2):38-42.
    • (2013) J Neuroimmunol. , vol.256 , Issue.1-2 , pp. 38-42
    • Zhang, R.1    Miller, R.G.2    Madison, C.3    Jin, X.4    Honrada, R.5    Harris, W.6
  • 13
    • 84856383137 scopus 로고    scopus 로고
    • CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer's disease
    • Westin K, Buchhave P, Nielsen H, Minthon L, Janciauskiene S, Hansson O. CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer's disease. PLoS One. 2012;7(1):e30525.
    • (2012) PLoS One. , vol.7 , Issue.1
    • Westin, K.1    Buchhave, P.2    Nielsen, H.3    Minthon, L.4    Janciauskiene, S.5    Hansson, O.6
  • 14
    • 80051547200 scopus 로고    scopus 로고
    • Cerebrospinal fluid microglial markers in Alzheimer's disease: Elevated chitotriosidase activity but lack of diagnostic utility
    • Mattsson N, Tabatabaei S, Johansson P, Hansson O, Andreasson U, Mansson JE, et al. Cerebrospinal fluid microglial markers in Alzheimer's disease: elevated chitotriosidase activity but lack of diagnostic utility. Neuromolecular Med. 2011;13(2): 151-9.
    • (2011) Neuromolecular Med. , vol.13 , Issue.2 , pp. 151-159
    • Mattsson, N.1    Tabatabaei, S.2    Johansson, P.3    Hansson, O.4    Andreasson, U.5    Mansson, J.E.6
  • 15
    • 33749998363 scopus 로고    scopus 로고
    • Serum MCP-1 levels are increased inmild cognitive impairment and mild Alzheimer's disease
    • Galimberti D, Fenoglio C, Lovati C, Venturelli E, Guidi I, Corra B, et al. Serum MCP-1 levels are increased inmild cognitive impairment and mild Alzheimer's disease. Neurobiol Aging. 2006;27(12):1763-8.
    • (2006) Neurobiol Aging. , vol.27 , Issue.12 , pp. 1763-1768
    • Galimberti, D.1    Fenoglio, C.2    Lovati, C.3    Venturelli, E.4    Guidi, I.5    Corra, B.6
  • 16
    • 0030988629 scopus 로고    scopus 로고
    • Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease
    • Ishizuka K, Kimura T, Igata-Yi R, Katsuragi S, Takamatsu J, Miyakawa T. Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease. Psychiatry Clin Neurosci. 1997;51(3):135-8.
    • (1997) Psychiatry Clin Neurosci. , vol.51 , Issue.3 , pp. 135-138
    • Ishizuka, K.1    Kimura, T.2    Igata-Yi, R.3    Katsuragi, S.4    Takamatsu, J.5    Miyakawa, T.6
  • 17
    • 2542481651 scopus 로고    scopus 로고
    • Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease
    • Nagele RG, Wegiel J, Venkataraman V, Imaki H, Wang KC, Wegiel J. Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease. Neurobiol Aging. 2004;25(5):663-74.
    • (2004) Neurobiol Aging. , vol.25 , Issue.5 , pp. 663-674
    • Nagele, R.G.1    Wegiel, J.2    Venkataraman, V.3    Imaki, H.4    Wang, K.C.5    Wegiel, J.6
  • 18
    • 84889606928 scopus 로고    scopus 로고
    • Bindarit, inhibitor of CCL2 synthesis, protects neurons against amyloid-beta- induced toxicity
    • Severini C, Passeri PP, Ciotti M, Florenzano F, Possenti R, Zona C, et al. Bindarit, inhibitor of CCL2 synthesis, protects neurons against amyloid-beta- induced toxicity. J Alzheimers Dis. 2014;38(2):281-93.
    • (2014) J Alzheimers Dis. , vol.38 , Issue.2 , pp. 281-293
    • Severini, C.1    Passeri, P.P.2    Ciotti, M.3    Florenzano, F.4    Possenti, R.5    Zona, C.6
  • 19
    • 67650539049 scopus 로고    scopus 로고
    • CCL2 accelerates microglia- mediated Abeta oligomer formation and progression of neurocognitive dysfunction
    • Kiyota T, Yamamoto M, Xiong H, Lambert MP, Klein WL, Gendelman HE, et al. CCL2 accelerates microglia- mediated Abeta oligomer formation and progression of neurocognitive dysfunction. PLoS One. 2009;4(7):e6197.
    • (2009) PLoS One. , vol.4 , Issue.7
    • Kiyota, T.1    Yamamoto, M.2    Xiong, H.3    Lambert, M.P.4    Klein, W.L.5    Gendelman, H.E.6
  • 20
    • 17844375420 scopus 로고    scopus 로고
    • Overexpression of monocyte chemotactic protein-1/CCL2 in betaamyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition
    • Yamamoto M, Horiba M, Buescher JL, Huang D, Gendelman HE, Ransohoff RM, et al. Overexpression of monocyte chemotactic protein-1/CCL2 in betaamyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition. Am J Pathol. 2005;166(5):1475-85.
    • (2005) Am J Pathol. , vol.166 , Issue.5 , pp. 1475-1485
    • Yamamoto, M.1    Horiba, M.2    Buescher, J.L.3    Huang, D.4    Gendelman, H.E.5    Ransohoff, R.M.6
  • 21
    • 84872354623 scopus 로고    scopus 로고
    • CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease
    • Kiyota T, Gendelman HE, Weir RA, Higgins EE, Zhang G, Jain M. CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease. Neurobiol Aging. 2013;34(4):1060-8.
    • (2013) Neurobiol Aging. , vol.34 , Issue.4 , pp. 1060-1068
    • Kiyota, T.1    Gendelman, H.E.2    Weir, R.A.3    Higgins, E.E.4    Zhang, G.5    Jain, M.6
  • 22
    • 34147115541 scopus 로고    scopus 로고
    • Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
    • El KJ, Toft M, Hickman SE, Means TK, Terada K, Geula C, et al. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med. 2007;13(4):432-8.
    • (2007) Nat Med. , vol.13 , Issue.4 , pp. 432-438
    • El, K.J.1    Toft, M.2    Hickman, S.E.3    Means, T.K.4    Terada, K.5    Geula, C.6
  • 23
    • 79955775349 scopus 로고    scopus 로고
    • CC chemokine receptor 2 defi- ciency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease
    • Naert G, Rivest S. CC chemokine receptor 2 defi- ciency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease. J Neurosci. 2011;31(16):6208-20.
    • (2011) J Neurosci. , vol.31 , Issue.16 , pp. 6208-6220
    • Naert, G.1    Rivest, S.2
  • 24
    • 79751533971 scopus 로고    scopus 로고
    • CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-beta-induced apoptosis
    • Bruban J, Maoui A, Chalour N, An N, Jonet L, Feumi C, et al. CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-beta-induced apoptosis. Neurobiol Dis. 2011;42(1):55-72.
    • (2011) Neurobiol Dis. , vol.42 , Issue.1 , pp. 55-72
    • Bruban, J.1    Maoui, A.2    Chalour, N.3    An, N.4    Jonet, L.5    Feumi, C.6
  • 25
    • 0019872434 scopus 로고
    • Selective loss of neurones of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia
    • Bondareff W, Mountjoy CQ, Roth M. Selective loss of neurones of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia. Lancet. 1981;1(8223):783-4.
    • (1981) Lancet. , vol.1 , Issue.8223 , pp. 783-784
    • Bondareff, W.1    Mountjoy, C.Q.2    Roth, M.3
  • 27
  • 28
    • 77956955758 scopus 로고    scopus 로고
    • The role of microglia in amyloid clearance from the AD brain
    • Lee CY, Landreth GE. The role of microglia in amyloid clearance from the AD brain. J Neural Transm. 2010;117(8):949-60.
    • (2010) J Neural Transm. , vol.117 , Issue.8 , pp. 949-960
    • Lee, C.Y.1    Landreth, G.E.2
  • 29
    • 0034617343 scopus 로고    scopus 로고
    • Neuroprotective activity of chemokines against N-methyl-D-aspartate or beta-amyloid-induced toxicity in culture
    • Bruno V, Copani A, Besong G, Scoto G, Nicoletti F. Neuroprotective activity of chemokines against N-methyl-D-aspartate or beta-amyloid-induced toxicity in culture. Eur J Pharmacol. 2000;399(2-3):117-21.
    • (2000) Eur J Pharmacol. , vol.399 , Issue.2-3 , pp. 117-121
    • Bruno, V.1    Copani, A.2    Besong, G.3    Scoto, G.4    Nicoletti, F.5
  • 30
    • 0038579653 scopus 로고    scopus 로고
    • MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis
    • Eugenin EA, D'Aversa TG, Lopez L, Calderon TM, Berman JW. MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis. J Neurochem. 2003;85(5):1299-311.
    • (2003) J Neurochem. , vol.85 , Issue.5 , pp. 1299-1311
    • Eugenin, E.A.1    D'aversa, T.G.2    Lopez, L.3    Calderon, T.M.4    Berman, J.W.5
  • 31
    • 0033816844 scopus 로고    scopus 로고
    • Beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis
    • Harkany T, Abraham I, Timmerman W, Laskay G, Toth B, Sasvari M, et al. beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis. Eur J Neurosci. 2000;12(8):2735-45.
    • (2000) Eur J Neurosci. , vol.12 , Issue.8 , pp. 2735-2745
    • Harkany, T.1    Abraham, I.2    Timmerman, W.3    Laskay, G.4    Toth, B.5    Sasvari, M.6
  • 32
    • 84874629526 scopus 로고    scopus 로고
    • Metabotropic NMDA receptor function is required for betaamyloid- induced synaptic depression
    • Kessels HW, Nabavi S, Malinow R. Metabotropic NMDA receptor function is required for betaamyloid- induced synaptic depression. Proc Natl Acad Sci U S A. 2013;110(10):4033-8.
    • (2013) Proc Natl Acad Sci U S A. , vol.110 , Issue.10 , pp. 4033-4038
    • Kessels, H.W.1    Nabavi, S.2    Malinow, R.3
  • 34
    • 84883771075 scopus 로고    scopus 로고
    • Cerebrospinal fluid inflammatory markers in Parkinson's disease - Associations with depression, fatigue, and cognitive impairment
    • Lindqvist D, Hall S, Surova Y, Nielsen HM, Janelidze S, Brundin L, et al. Cerebrospinal fluid inflammatory markers in Parkinson's disease - associations with depression, fatigue, and cognitive impairment. Brain Behav Immun. 2013;33:183-9.
    • (2013) Brain Behav Immun. , vol.33 , pp. 183-189
    • Lindqvist, D.1    Hall, S.2    Surova, Y.3    Nielsen, H.M.4    Janelidze, S.5    Brundin, L.6
  • 35
    • 33847681800 scopus 로고    scopus 로고
    • Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's disease
    • Pattarini R, Smeyne RJ, Morgan JI. Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's disease. Neuroscience. 2007;145(2):654-68.
    • (2007) Neuroscience. , vol.145 , Issue.2 , pp. 654-668
    • Pattarini, R.1    Smeyne, R.J.2    Morgan, J.I.3
  • 36
    • 33645123006 scopus 로고    scopus 로고
    • Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: Role of tumor necrosis factor-alpha
    • Sriram K, Miller DB, O'Callaghan JP. Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor-alpha. J Neurochem. 2006;96(3):706-18.
    • (2006) J Neurochem. , vol.96 , Issue.3 , pp. 706-718
    • Sriram, K.1    Miller, D.B.2    O'callaghan, J.P.3
  • 37
    • 33845980539 scopus 로고    scopus 로고
    • Chemokines in the MPTP model of Parkinson's disease: Absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration
    • Kalkonde YV, Morgan WW, Sigala J, Maffi SK, Condello C, Kuziel W, et al. Chemokines in the MPTP model of Parkinson's disease: absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration. Brain Res. 2007;1128(1):1-11.
    • (2007) Brain Res. , vol.1128 , Issue.1 , pp. 1-11
    • Kalkonde, Y.V.1    Morgan, W.W.2    Sigala, J.3    Maffi, S.K.4    Condello, C.5    Kuziel, W.6
  • 38
    • 68049123116 scopus 로고    scopus 로고
    • Long term exposure to the chemokine CCL2 activates the nigrostriatal dopamine system: A novel mechanism for the control of dopamine release
    • Guyon A, Skrzydelski D, De Giry I, Rovere C, Conductier G, Trocello JM, et al. Long term exposure to the chemokine CCL2 activates the nigrostriatal dopamine system: a novel mechanism for the control of dopamine release. Neuroscience. 2009;162(4):1072-80.
    • (2009) Neuroscience. , vol.162 , Issue.4 , pp. 1072-1080
    • Guyon, A.1    Skrzydelski, D.2    De Giry, I.3    Rovere, C.4    Conductier, G.5    Trocello, J.M.6
  • 39
    • 44749088863 scopus 로고    scopus 로고
    • The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons
    • Edman LC, Mira H, Arenas E. The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons. Exp Cell Res. 2008;314(10):2123-30.
    • (2008) Exp Cell Res. , vol.314 , Issue.10 , pp. 2123-2130
    • Edman, L.C.1    Mira, H.2    Arenas, E.3
  • 40
    • 56149119337 scopus 로고    scopus 로고
    • Glutamate forward and reverse transport: From molecular mechanism to transporter-mediated release after ischemia
    • Grewer C, Gameiro A, Zhang Z, Tao Z, Braams S, Rauen T. Glutamate forward and reverse transport: from molecular mechanism to transporter-mediated release after ischemia. IUBMB Life. 2008;60(9): 609-19.
    • (2008) IUBMB Life. , vol.60 , Issue.9 , pp. 609-619
    • Grewer, C.1    Gameiro, A.2    Zhang, Z.3    Tao, Z.4    Braams, S.5    Rauen, T.6
  • 41
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
    • Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med. 2009;7:97.
    • (2009) J Transl Med. , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 42
    • 34249008096 scopus 로고    scopus 로고
    • Chemokines in ischemia and reperfusion
    • Frangogiannis NG. Chemokines in ischemia and reperfusion. Thromb Haemost. 2007;97(5):738-47.
    • (2007) Thromb Haemost. , vol.97 , Issue.5 , pp. 738-747
    • Frangogiannis, N.G.1
  • 43
    • 0028893614 scopus 로고
    • Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein- 1 after focal cerebral ischemia in the rat
    • Kim JS, Gautam SC, Chopp M, Zaloga C, Jones ML, Ward PA, et al. Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein- 1 after focal cerebral ischemia in the rat. J Neuroimmunol. 1995;56(2):127-34.
    • (1995) J Neuroimmunol. , vol.56 , Issue.2 , pp. 127-134
    • Kim, J.S.1    Gautam, S.C.2    Chopp, M.3    Zaloga, C.4    Jones, M.L.5    Ward, P.A.6
  • 44
    • 0242289611 scopus 로고    scopus 로고
    • Chemokines and their receptors in the brain: Pathophysiological roles in ischemic brain injury
    • Minami M, Satoh M. Chemokines and their receptors in the brain: pathophysiological roles in ischemic brain injury. Life Sci. 2003;74(2-3):321-7.
    • (2003) Life Sci. , vol.74 , Issue.2-3 , pp. 321-327
    • Minami, M.1    Satoh, M.2
  • 45
    • 79957885653 scopus 로고    scopus 로고
    • Irbesartan attenuates ischemic brain damage by inhibition of MCP-1/CCR2 signaling pathway beyond AT(1) receptor blockade
    • Tsukuda K, Mogi M, Iwanami J, Min LJ, Jing F, Oshima K, et al. Irbesartan attenuates ischemic brain damage by inhibition of MCP-1/CCR2 signaling pathway beyond AT(1) receptor blockade. Biochem Biophys Res Commun. 2011;409(2):275-9.
    • (2011) Biochem Biophys Res Commun. , vol.409 , Issue.2 , pp. 275-279
    • Tsukuda, K.1    Mogi, M.2    Iwanami, J.3    Min, L.J.4    Jing, F.5    Oshima, K.6
  • 47
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic OB, Stamatovic SM, Keep RF, Andjelkovic AV. Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke. 2007;38(4):1345-53.
    • (2007) Stroke. , vol.38 , Issue.4 , pp. 1345-1353
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 48
    • 0035168891 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein- 1 is increased in the cerebrospinal fluid of patients with ischemic stroke
    • Losy J, Zaremba J. Monocyte chemoattractant protein- 1 is increased in the cerebrospinal fluid of patients with ischemic stroke. Stroke. 2001;32(11):2695-6.
    • (2001) Stroke. , vol.32 , Issue.11 , pp. 2695-2696
    • Losy, J.1    Zaremba, J.2
  • 49
    • 65749106380 scopus 로고    scopus 로고
    • Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice
    • Schilling M, Strecker JK, Schabitz WR, Ringelstein EB, Kiefer R. Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice. Neuroscience. 2009;161(3):806-12.
    • (2009) Neuroscience. , vol.161 , Issue.3 , pp. 806-812
    • Schilling, M.1    Strecker, J.K.2    Schabitz, W.R.3    Ringelstein, E.B.4    Kiefer, R.5
  • 50
    • 33645231127 scopus 로고    scopus 로고
    • Chemokines regulate the migration of neural progenitors to sites of neuroinflammation
    • Belmadani A, Tran PB, Ren D, Miller RJ. Chemokines regulate the migration of neural progenitors to sites of neuroinflammation. J Neurosci. 2006;26(12):3182-91.
    • (2006) J Neurosci. , vol.26 , Issue.12 , pp. 3182-3191
    • Belmadani, A.1    Tran, P.B.2    Ren, D.3    Miller, R.J.4
  • 51
    • 34547395911 scopus 로고    scopus 로고
    • Chemokine ligand 2 (CCL2) induces migration and differentiation of subventricular zone cells after stroke
    • Liu XS, Zhang ZG, Zhang RL, Gregg SR, Wang L, Yier T, et al. Chemokine ligand 2 (CCL2) induces migration and differentiation of subventricular zone cells after stroke. J Neurosci Res. 2007;85(10):2120-5.
    • (2007) J Neurosci Res. , vol.85 , Issue.10 , pp. 2120-2125
    • Liu, X.S.1    Zhang, Z.G.2    Zhang, R.L.3    Gregg, S.R.4    Wang, L.5    Yier, T.6
  • 52
    • 34249278458 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 plays a critical role in neuroblast migration after focal cerebral ischemia
    • Yan YP, Sailor KA, Lang BT, Park SW, Vemuganti R, Dempsey RJ. Monocyte chemoattractant protein-1 plays a critical role in neuroblast migration after focal cerebral ischemia. J Cereb Blood Flow Metab. 2007;27(6):1213-24.
    • (2007) J Cereb Blood Flow Metab. , vol.27 , Issue.6 , pp. 1213-1224
    • Yan, Y.P.1    Sailor, K.A.2    Lang, B.T.3    Park, S.W.4    Vemuganti, R.5    Dempsey, R.J.6
  • 53
    • 80053324852 scopus 로고    scopus 로고
    • The CCR2/CCL2 interaction mediates the transendothelial recruitment of intravascularly delivered neural stem cells to the ischemic brain
    • Andres RH, Choi R, Pendharkar AV, Gaeta X, Wang N, Nathan JK, et al. The CCR2/CCL2 interaction mediates the transendothelial recruitment of intravascularly delivered neural stem cells to the ischemic brain. Stroke. 2011;42(10):2923-31.
    • (2011) Stroke. , vol.42 , Issue.10 , pp. 2923-2931
    • Andres, R.H.1    Choi, R.2    Pendharkar, A.V.3    Gaeta, X.4    Wang, N.5    Nathan, J.K.6
  • 54
    • 84874794985 scopus 로고    scopus 로고
    • Expression of MCP-1 and fractalkine on endothelial cells and astrocytes may contribute to the invasion and migration of brain macrophages in ischemic rat brain lesions
    • Tei N, Tanaka J, Sugimoto K, Nishihara T, Nishioka R, Takahashi H, et al. Expression of MCP-1 and fractalkine on endothelial cells and astrocytes may contribute to the invasion and migration of brain macrophages in ischemic rat brain lesions. J Neurosci Res. 2013;91(5):681-93.
    • (2013) J Neurosci Res. , vol.91 , Issue.5 , pp. 681-693
    • Tei, N.1    Tanaka, J.2    Sugimoto, K.3    Nishihara, T.4    Nishioka, R.5    Takahashi, H.6
  • 56
    • 0030584891 scopus 로고    scopus 로고
    • Localization of monocyte chemoattractant peptide- 1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat
    • Berman JW, Guida MP, Warren J, Amat J, Brosnan CF. Localization of monocyte chemoattractant peptide- 1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat. J Immunol. 1996;156(8): 3017-23.
    • (1996) J Immunol. , vol.156 , Issue.8 , pp. 3017-3023
    • Berman, J.W.1    Guida, M.P.2    Warren, J.3    Amat, J.4    Brosnan, C.F.5
  • 57
    • 0029931236 scopus 로고    scopus 로고
    • Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain
    • Glabinski AR, Balasingam V, Tani M, Kunkel SL, Strieter RM, Yong VW, et al. Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J Immunol. 1996;156(11):4363-8.
    • (1996) J Immunol. , vol.156 , Issue.11 , pp. 4363-4368
    • Glabinski, A.R.1    Balasingam, V.2    Tani, M.3    Kunkel, S.L.4    Strieter, R.M.5    Yong, V.W.6
  • 58
    • 13144279282 scopus 로고    scopus 로고
    • Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
    • Harrison JK, Jiang Y, Chen S, Xia Y, Maciejewski D, McNamara RK, et al. Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci U S A. 1998;95(18):10896-901.
    • (1998) Proc Natl Acad Sci U S A. , vol.95 , Issue.18 , pp. 10896-10901
    • Harrison, J.K.1    Jiang, Y.2    Chen, S.3    Xia, Y.4    Maciejewski, D.5    McNamara, R.K.6
  • 60
    • 58149392087 scopus 로고    scopus 로고
    • Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline
    • Madrigal JL, Leza JC, Polak P, Kalinin S, Feinstein DL. Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. J Neurosci. 2009;29(1):263-7.
    • (2009) J Neurosci. , vol.29 , Issue.1 , pp. 263-267
    • Madrigal, J.L.1    Leza, J.C.2    Polak, P.3    Kalinin, S.4    Feinstein, D.L.5
  • 61
    • 80555154358 scopus 로고    scopus 로고
    • Evaluation of serum levels of chemokines during interferon-beta treatment in multiple sclerosis patients: A 1-year, observational cohort study
    • Comini-Frota ER, Teixeira AL, Angelo JP, Andrade MV, Brum DG, Kaimen-Maciel DR, et al. Evaluation of serum levels of chemokines during interferon-beta treatment in multiple sclerosis patients: a 1-year, observational cohort study. CNS Drugs. 2011;25(11):971-81.
    • (2011) CNS Drugs. , vol.25 , Issue.11 , pp. 971-981
    • Comini-Frota, E.R.1    Teixeira, A.L.2    Angelo, J.P.3    Andrade, M.V.4    Brum, D.G.5    Kaimen-Maciel, D.R.6
  • 62
    • 0032100683 scopus 로고    scopus 로고
    • MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: An immunohistochemical and in situ hybridization study
    • McManus C, Berman JW, Brett FM, Staunton H, Farrell M, Brosnan CF. MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study. J Neuroimmunol. 1998;86(1):20-9.
    • (1998) J Neuroimmunol. , vol.86 , Issue.1 , pp. 20-29
    • McManus, C.1    Berman, J.W.2    Brett, F.M.3    Staunton, H.4    Farrell, M.5    Brosnan, C.F.6
  • 63
    • 0032522207 scopus 로고    scopus 로고
    • Expression of monocyte chemoattractant protein- 1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions
    • Simpson JE, Newcombe J, Cuzner ML, Woodroofe MN. Expression of monocyte chemoattractant protein- 1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions. J Neuroimmunol. 1998;84(2):238-49.
    • (1998) J Neuroimmunol. , vol.84 , Issue.2 , pp. 238-249
    • Simpson, J.E.1    Newcombe, J.2    Cuzner, M.L.3    Woodroofe, M.N.4
  • 64
    • 0034256028 scopus 로고    scopus 로고
    • Expression of the beta-chemokine receptors CCR2, CCR3 and CCR5 in multiple sclerosis central nervous system tissue
    • Simpson J, Rezaie P, Newcombe J, Cuzner ML, Male D, Woodroofe MN. Expression of the beta-chemokine receptors CCR2, CCR3 and CCR5 in multiple sclerosis central nervous system tissue. J Neuroimmunol. 2000;108(1-2):192-200.
    • (2000) J Neuroimmunol. , vol.108 , Issue.1-2 , pp. 192-200
    • Simpson, J.1    Rezaie, P.2    Newcombe, J.3    Cuzner, M.L.4    Male, D.5    Woodroofe, M.N.6
  • 65
    • 0033807680 scopus 로고    scopus 로고
    • CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis
    • Fife BT, Huffnagle GB, Kuziel WA, Karpus WJ. CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis. J Exp Med. 2000;192(6):899-905.
    • (2000) J Exp Med. , vol.192 , Issue.6 , pp. 899-905
    • Fife, B.T.1    Huffnagle, G.B.2    Kuziel, W.A.3    Karpus, W.J.4
  • 66
    • 0034596949 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
    • Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med. 2000;192(7):1075-80.
    • (2000) J Exp Med. , vol.192 , Issue.7 , pp. 1075-1080
    • Izikson, L.1    Klein, R.S.2    Charo, I.F.3    Weiner, H.L.4    Luster, A.D.5
  • 67
    • 84863642413 scopus 로고    scopus 로고
    • The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis
    • Ge S, Shrestha B, Paul D, Keating C, Cone R, Guglielmotti A, et al. The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis. J Neuroinflammation. 2012;9:171.
    • (2012) J Neuroinflammation. , vol.9 , pp. 171
    • Ge, S.1    Shrestha, B.2    Paul, D.3    Keating, C.4    Cone, R.5    Guglielmotti, A.6
  • 68
    • 14644441733 scopus 로고    scopus 로고
    • Transgenic expression of CCL2 in the central nervous system prevents experimental autoimmune encephalomyelitis
    • Elhofy A, Wang J, Tani M, Fife BT, Kennedy KJ, Bennett J, et al. Transgenic expression of CCL2 in the central nervous system prevents experimental autoimmune encephalomyelitis. J Leukoc Biol. 2005;77(2):229-37.
    • (2005) J Leukoc Biol. , vol.77 , Issue.2 , pp. 229-237
    • Elhofy, A.1    Wang, J.2    Tani, M.3    Fife, B.T.4    Kennedy, K.J.5    Bennett, J.6
  • 69
    • 25844496913 scopus 로고    scopus 로고
    • Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis
    • Baron P, Bussini S, Cardin V, Corbo M, Conti G, Galimberti D, et al. Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis. Muscle Nerve. 2005;32(4):541-4.
    • (2005) Muscle Nerve. , vol.32 , Issue.4 , pp. 541-544
    • Baron, P.1    Bussini, S.2    Cardin, V.3    Corbo, M.4    Conti, G.5    Galimberti, D.6
  • 70
    • 80052599853 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients
    • Gupta PK, Prabhakar S, Abburi C, Sharma NK, Anand A. Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients. J Neuroinflammation. 2011;8:114.
    • (2011) J Neuroinflammation. , vol.8 , pp. 114
    • Gupta, P.K.1    Prabhakar, S.2    Abburi, C.3    Sharma, N.K.4    Anand, A.5
  • 71
    • 77955983504 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorder: Pathogenesis and therapeutic opportunities
    • Lindl KA, Marks DR, Kolson DL, Jordan-Sciutto KL. HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J Neuroimmune Pharmacol. 2010;5(3):294-309.
    • (2010) J Neuroimmune Pharmacol. , vol.5 , Issue.3 , pp. 294-309
    • Lindl, K.A.1    Marks, D.R.2    Kolson, D.L.3    Jordan-Sciutto, K.L.4
  • 72
    • 0034529953 scopus 로고    scopus 로고
    • Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands
    • Liu Y, Jones M, Hingtgen CM, Bu G, Laribee N, Tanzi RE, et al. Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands. Nat Med. 2000;6(12):1380-7.
    • (2000) Nat Med. , vol.6 , Issue.12 , pp. 1380-1387
    • Liu, Y.1    Jones, M.2    Hingtgen, C.M.3    Bu, G.4    Laribee, N.5    Tanzi, R.E.6
  • 73
    • 0025609978 scopus 로고
    • Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
    • Giulian D, Vaca K, Noonan CA. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1 Science. 1990;250(4987):1593-6.
    • (1990) Science , vol.250 , Issue.4987 , pp. 1593-1596
    • Giulian, D.1    Vaca, K.2    Noonan, C.A.3
  • 74
    • 0025963498 scopus 로고
    • Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains
    • Pulliam L, Herndier BG, Tang NM, McGrath MS. Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains. J Clin Invest. 1991;87(2):503-12.
    • (1991) J Clin Invest. , vol.87 , Issue.2 , pp. 503-512
    • Pulliam, L.1    Herndier, B.G.2    Tang, N.M.3    McGrath, M.S.4
  • 75
    • 15144361055 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication
    • Cinque P, Vago L, Mengozzi M, Torri V, Ceresa D, Vicenzi E, et al. Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication. AIDS. 1998;12(11):1327-32.
    • (1998) AIDS , vol.12 , Issue.11 , pp. 1327-1332
    • Cinque, P.1    Vago, L.2    Mengozzi, M.3    Torri, V.4    Ceresa, D.5    Vicenzi, E.6
  • 76
    • 0031737417 scopus 로고    scopus 로고
    • Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia
    • Kelder W, McArthur JC, Nance-Sproson T, McClernon D, Griffin DE. Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia. Ann Neurol. 1998;44(5):831-5.
    • (1998) Ann Neurol. , vol.44 , Issue.5 , pp. 831-835
    • Kelder, W.1    McArthur, J.C.2    Nance-Sproson, T.3    McClernon, D.4    Griffin, D.E.5
  • 77
    • 79956097572 scopus 로고    scopus 로고
    • Extracellular HIV-1 Tat upregulates TNF-alpha dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: Inhibition by resveratrol, a polyphenolic phytostilbene
    • Lee EO, Kim SE, Park HK, Kang JL, Chong YH. Extracellular HIV-1 Tat upregulates TNF-alpha dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: inhibition by resveratrol, a polyphenolic phytostilbene. Exp Neurol. 2011;229(2):399-408.
    • (2011) Exp Neurol. , vol.229 , Issue.2 , pp. 399-408
    • Lee, E.O.1    Kim, S.E.2    Park, H.K.3    Kang, J.L.4    Chong, Y.H.5
  • 78
    • 0037262112 scopus 로고    scopus 로고
    • HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium
    • Toborek M, Lee YW, Pu H, Malecki A, Flora G, Garrido R, et al. HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium. J Neurochem. 2003;84(1):169-79.
    • (2003) J Neurochem. , vol.84 , Issue.1 , pp. 169-179
    • Toborek, M.1    Lee, Y.W.2    Pu, H.3    Malecki, A.4    Flora, G.5    Garrido, R.6
  • 79
    • 60749137640 scopus 로고    scopus 로고
    • Involvement of TRPC channels in CCL2-mediated neuroprotection against tat toxicity
    • Yao H, Peng F, Dhillon N, Callen S, Bokhari S, Stehno-Bittel L, et al. Involvement of TRPC channels in CCL2-mediated neuroprotection against tat toxicity. J Neurosci. 2009;29(6):1657-69.
    • (2009) J Neurosci. , vol.29 , Issue.6 , pp. 1657-1669
    • Yao, H.1    Peng, F.2    Dhillon, N.3    Callen, S.4    Bokhari, S.5    Stehno-Bittel, L.6
  • 80
    • 46449109626 scopus 로고    scopus 로고
    • Patients with schizophrenia show raised serum levels of the pro- inflammatory chemokine CCL2: Association with the metabolic syndrome in patients?
    • Drexhage RC, Padmos RC, de Wit H, Versnel MA, Hooijkaas H, van der Lely AJ, et al. Patients with schizophrenia show raised serum levels of the pro- inflammatory chemokine CCL2: association with the metabolic syndrome in patients? Schizophr Res. 2008;102(1-3): 352-5.
    • (2008) Schizophr Res. , vol.102 , Issue.1-3 , pp. 352-355
    • Drexhage, R.C.1    Padmos, R.C.2    De Wit, H.3    Versnel, M.A.4    Hooijkaas, H.5    Van Der Lely, A.J.6
  • 81
    • 77950520442 scopus 로고    scopus 로고
    • Role of CCL2 (MCP-1) in traumatic brain injury (TBI): Evidence from severe TBI patients and CCL2-/- mice
    • Semple BD, Bye N, Rancan M, Ziebell JM, Morganti- Kossmann MC. Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2-/- mice. J Cereb Blood Flow Metab. 2010;30(4):769-82.
    • (2010) J Cereb Blood Flow Metab. , vol.30 , Issue.4 , pp. 769-782
    • Semple, B.D.1    Bye, N.2    Rancan, M.3    Ziebell, J.M.4    Morganti-Kossmann, M.C.5
  • 82
    • 41149139537 scopus 로고    scopus 로고
    • Expression of monocyte chemoattractant protein-1 in brain tissue of patients with intractable epilepsy
    • Wu Y, Wang X, Mo X, Xi Z, Xiao F, Li J, et al. Expression of monocyte chemoattractant protein-1 in brain tissue of patients with intractable epilepsy. Clin Neuropathol. 2008;27(2):55-63.
    • (2008) Clin Neuropathol. , vol.27 , Issue.2 , pp. 55-63
    • Wu, Y.1    Wang, X.2    Mo, X.3    Xi, Z.4    Xiao, F.5    Li, J.6
  • 83
    • 84857563634 scopus 로고    scopus 로고
    • CXCL16 orchestrates adenosine A3 receptor and MCP-1/CCL2 activity to protect neurons from excitotoxic cell death in the CNS
    • Rosito M, Deflorio C, Limatola C, Trettel F. CXCL16 orchestrates adenosine A3 receptor and MCP-1/CCL2 activity to protect neurons from excitotoxic cell death in the CNS. J Neurosci. 2012;32(9):3154-63.
    • (2012) J Neurosci. , vol.32 , Issue.9 , pp. 3154-3163
    • Rosito, M.1    Deflorio, C.2    Limatola, C.3    Trettel, F.4
  • 85
    • 84873386607 scopus 로고    scopus 로고
    • Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression
    • Bray JG, Reyes KC, Roberts AJ, Ransohoff RM, Gruol DL. Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression. Neuropharmacology. 2013;67:115-25.
    • (2013) Neuropharmacology. , vol.67 , pp. 115-125
    • Bray, J.G.1    Reyes, K.C.2    Roberts, A.J.3    Ransohoff, R.M.4    Gruol, D.L.5
  • 87
    • 0034653895 scopus 로고    scopus 로고
    • Selective suppression of IL-12 production by chemoattractants
    • Braun MC, Lahey E, Kelsall BL. Selective suppression of IL-12 production by chemoattractants. J Immunol. 2000;164(6):3009-17.
    • (2000) J Immunol. , vol.164 , Issue.6 , pp. 3009-3017
    • Braun, M.C.1    Lahey, E.2    Kelsall, B.L.3
  • 89
    • 33645222277 scopus 로고    scopus 로고
    • Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain
    • Aberg ND, Brywe KG, Isgaard J. Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain. ScientificWorldJournal. 2006; 6:53-80.
    • (2006) ScientificWorldJournal. , vol.6 , pp. 53-80
    • Aberg, N.D.1    Brywe, K.G.2    Isgaard, J.3
  • 90
    • 75949099155 scopus 로고    scopus 로고
    • Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma
    • Chiu K, Yeung SC, So KF, Chang RC. Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma. Cell Mol Immunol. 2010; 7(1):61-8.
    • (2010) Cell Mol Immunol. , vol.7 , Issue.1 , pp. 61-68
    • Chiu, K.1    Yeung, S.C.2    So, K.F.3    Chang, R.C.4
  • 91
    • 84880025391 scopus 로고    scopus 로고
    • Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators
    • Hinojosa AE, Caso JR, Garcia-Bueno B, Leza JC, Madrigal JL. Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators. J Neuroinflammation. 2013;10(1):81.
    • (2013) J Neuroinflammation. , vol.10 , Issue.1 , pp. 81
    • Hinojosa, A.E.1    Caso, J.R.2    Garcia-Bueno, B.3    Leza, J.C.4    Madrigal, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.