-
1
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M et al (2003) LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302:415-419
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
2
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff JA, Malone RW, Williams P et al (1990) Direct gene transfer into mouse muscle in vivo. Science 247:1465-1468
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
-
3
-
-
0028670903
-
Gene expression following direct injection of DNA into liver
-
Hickman MA, Malone RW, Lehmann-Bruinsma K et al (1994) Gene expression following direct injection of DNA into liver. Hum Gene Ther 5: 1477-1483
-
(1994)
Hum Gene Ther
, vol.5
, pp. 1477-1483
-
-
Hickman, M.A.1
Malone, R.W.2
Lehmann-Bruinsma, K.3
-
4
-
-
0029781318
-
Naked DNA delivered intraportally expresses ef fi ciently in hepatocytes
-
Budker V, Zhang G, Knechtle S et al (1996) Naked DNA delivered intraportally expresses ef fi ciently in hepatocytes. Gene Ther 3:593-598
-
(1996)
Gene Ther
, vol.3
, pp. 593-598
-
-
Budker, V.1
Zhang, G.2
Knechtle, S.3
-
5
-
-
0031580664
-
Direct cutaneous gene delivery in a human genetic skin disease
-
Choate KA, Khavari PA (1997) Direct cutaneous gene delivery in a human genetic skin disease. Hum Gene Ther 8:1659-1665
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1659-1665
-
-
Choate, K.A.1
Khavari, P.A.2
-
6
-
-
0029078539
-
Intratracheal gene delivery to the mouse airway: Characterization of plasmid DNA expression and pharmacokinetics
-
Meyer KB, Thompson MM, Levy MY et al (1995) Intratracheal gene delivery to the mouse airway: characterization of plasmid DNA expression and pharmacokinetics. Gene Ther 2: 450-460
-
(1995)
Gene Ther
, vol.2
, pp. 450-460
-
-
Meyer, K.B.1
Thompson, M.M.2
Levy, M.Y.3
-
7
-
-
20144389391
-
Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients
-
Reilly JP, Grise MA, Fortuin FD et al (2005) Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients. J Interv Cardiol 18:27-31
-
(2005)
J Interv Cardiol
, vol.18
, pp. 27-31
-
-
Reilly, J.P.1
Grise, M.A.2
Fortuin, F.D.3
-
8
-
-
0029998364
-
Gene transfer by naked DNA into adult mouse brain
-
Schwartz B, Benoist C, Abdallah B et al (1996) Gene transfer by naked DNA into adult mouse brain. Gene Ther 3:405-411
-
(1996)
Gene Ther
, vol.3
, pp. 405-411
-
-
Schwartz, B.1
Benoist, C.2
Abdallah, B.3
-
9
-
-
0031559914
-
Bacterial beta-galactosidase and human dystrophin genes are expressed in mouse skeletal muscle fi bers after ballistic transfection
-
Zelenin AV, Kolesnikov VA, Tarasenko OA et al (1997) Bacterial beta-galactosidase and human dystrophin genes are expressed in mouse skeletal muscle fi bers after ballistic transfection. FEBS Lett 414:319-322
-
(1997)
FEBS Lett
, vol.414
, pp. 319-322
-
-
Zelenin, A.V.1
Kolesnikov, V.A.2
Tarasenko, O.A.3
-
10
-
-
14744290978
-
Physical methods for gene transfer: Improving the kinetics of gene delivery into cells
-
Mehier-Humbert S, Guy RH (2005) Physical methods for gene transfer: improving the kinetics of gene delivery into cells. Adv Drug Deliv Rev 57:733-753
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 733-753
-
-
Mehier-Humbert, S.1
Guy, R.H.2
-
11
-
-
34247855110
-
Nonviral gene delivery: What we know and what is next
-
Gao X, Kim KS, Liu D (2007) Nonviral gene delivery: what we know and what is next. AAPS J 9:E92-104
-
(2007)
AAPS J
, vol.9
-
-
Gao, X.1
Kim, K.S.2
Liu, D.3
-
12
-
-
0037066034
-
Local delivery of plasmid DNA into rat carotid artery using ultrasound
-
Taniyama Y, Tachibana K, Hiraoka K et al (2002) Local delivery of plasmid DNA into rat carotid artery using ultrasound. Circulation 105:1233-1239
-
(2002)
Circulation
, vol.105
, pp. 1233-1239
-
-
Taniyama, Y.1
Tachibana, K.2
Hiraoka, K.3
-
13
-
-
0036227368
-
Development of safe and ef fi cient novel nonviral gene transfer using ultrasound: Enhancement of transfection ef fi ciency of naked plasmid DNA in skeletal muscle
-
Taniyama Y, Tachibana K, Hiraoka K et al (2002) Development of safe and ef fi cient novel nonviral gene transfer using ultrasound: enhancement of transfection ef fi ciency of naked plasmid DNA in skeletal muscle. Gene Ther 9: 372-380
-
(2002)
Gene Ther
, vol.9
, pp. 372-380
-
-
Taniyama, Y.1
Tachibana, K.2
Hiraoka, K.3
-
14
-
-
0034502618
-
Microbubble-enhanced ultrasound for vascular gene delivery
-
Lawrie A, Brisken AF, Francis SE et al (2000) Microbubble-enhanced ultrasound for vascular gene delivery. Gene Ther 7:2023-2027
-
(2000)
Gene Ther
, vol.7
, pp. 2023-2027
-
-
Lawrie, A.1
Brisken, A.F.2
Francis, S.E.3
-
15
-
-
4644371368
-
Gene therapy progress and prospects: Electroporation and other physical methods
-
Wells DJ (2004) Gene therapy progress and prospects: electroporation and other physical methods. Gene Ther 11:1363-1369
-
(2004)
Gene Ther
, vol.11
, pp. 1363-1369
-
-
Wells, D.J.1
-
16
-
-
0025938020
-
Conditions affecting direct gene transfer into rodent muscle in vivo
-
Wolff JA, Williams P, Acsadi G et al (1991) Conditions affecting direct gene transfer into rodent muscle in vivo. Biotechniques 11: 474-485
-
(1991)
Biotechniques
, vol.11
, pp. 474-485
-
-
Wolff, J.A.1
Williams, P.2
Acsadi, G.3
-
17
-
-
0032805251
-
Hydrodynamicsbased transfection in animals by systemic administration of plasmid DNA
-
Liu F, Song Y, Liu D (1999) Hydrodynamicsbased transfection in animals by systemic administration of plasmid DNA. Gene Ther 6: 1258-1266
-
(1999)
Gene Ther
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
18
-
-
0033166561
-
High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
-
Zhang G, Budker V, Wolff JA (1999) High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. Hum Gene Ther 10:1735-1737
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1735-1737
-
-
Zhang, G.1
Budker, V.2
Wolff, J.A.3
-
19
-
-
0031935395
-
The ef fi cient expression of intravascularly delivered DNA in rat muscle
-
Budker V, Zhang G, Danko I et al (1998) The ef fi cient expression of intravascularly delivered DNA in rat muscle. Gene Ther 5:272-276
-
(1998)
Gene Ther
, vol.5
, pp. 272-276
-
-
Budker, V.1
Zhang, G.2
Danko, I.3
-
20
-
-
1942537809
-
Hydroporation as the mechanism of hydrodynamic delivery
-
Zhang G, Gao X, Song YK et al (2004) Hydroporation as the mechanism of hydrodynamic delivery. Gene Ther 11:675-682
-
(2004)
Gene Ther
, vol.11
, pp. 675-682
-
-
Zhang, G.1
Gao, X.2
Song, Y.K.3
-
21
-
-
0030890713
-
Nonviral vectors for in vivo gene delivery: Physicochemical and pharmacokinetic considerations
-
Mahato RI, Takakura Y, Hashida M (1997) Nonviral vectors for in vivo gene delivery: physicochemical and pharmacokinetic considerations. Crit Rev Ther Drug Carrier Syst 14:133-172
-
(1997)
Crit Rev Ther Drug Carrier Syst
, vol.14
, pp. 133-172
-
-
Mahato, R.I.1
Takakura, Y.2
Hashida, M.3
-
22
-
-
0028863071
-
Physicochemical and pharmacokinetic characteristics of plasmid DNA/cationic liposome complexes
-
Mahato RI, Kawabata K, Nomura T et al (1995) Physicochemical and pharmacokinetic characteristics of plasmid DNA/cationic liposome complexes. J Pharm Sci 84:1267-1271
-
(1995)
J Pharm Sci
, vol.84
, pp. 1267-1271
-
-
Mahato, R.I.1
Kawabata, K.2
Nomura, T.3
-
23
-
-
0023447252
-
Lipofection: A highly ef fi cient, lipid-mediated DNA-transfection procedure
-
Felgner PL, Gadek TR, Holm M et al (1987) Lipofection: a highly ef fi cient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci U S A 84:7413-7417
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
-
24
-
-
0037805562
-
Cationic transfection lipids
-
Liu D, Ren T, Gao X (2003) Cationic transfection lipids. Curr Med Chem 10:1307-1315
-
(2003)
Curr Med Chem
, vol.10
, pp. 1307-1315
-
-
Liu, D.1
Ren, T.2
Gao, X.3
-
25
-
-
0033972869
-
Nonviral gene therapy: Promises and challenges
-
Li S, Huang L (2000) Nonviral gene therapy: promises and challenges. Gene Ther 7:31-34
-
(2000)
Gene Ther
, vol.7
, pp. 31-34
-
-
Li, S.1
Huang, L.2
-
26
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T et al (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408:740-745
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
27
-
-
59649128201
-
Evaluation of proin fl ammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice
-
Ito Y, Kawakami S, Charoensit P et al (2009) Evaluation of proin fl ammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice. Eur J Pharm Biopharm 71:303-309
-
(2009)
Eur J Pharm Biopharm
, vol.71
, pp. 303-309
-
-
Ito, Y.1
Kawakami, S.2
Charoensit, P.3
-
28
-
-
0036954247
-
Gene therapy progress and prospects: Nonviral vectors
-
Niidome T, Huang L (2002) Gene therapy progress and prospects: nonviral vectors. Gene Ther 9:1647-1652
-
(2002)
Gene Ther
, vol.9
, pp. 1647-1652
-
-
Niidome, T.1
Huang, L.2
-
29
-
-
0036157772
-
Overcoming the nuclear barrier: Cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation
-
Brunner S, Furtbauer E, Sauer T et al (2002) Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation. Mol Ther 5: 80-86
-
(2002)
Mol Ther
, vol.5
, pp. 80-86
-
-
Brunner, S.1
Furtbauer, E.2
Sauer, T.3
-
30
-
-
33646814034
-
Evaluation of proin fl ammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice
-
Kawakami S, Ito Y, Charoensit P et al (2006) Evaluation of proin fl ammatory cytokine production induced by linear and branched polyethylenimine/ plasmid DNA complexes in mice. J Pharmacol Exp Ther 317:1382-1390
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 1382-1390
-
-
Kawakami, S.1
Ito, Y.2
Charoensit, P.3
-
31
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
Boussif O, Lezoualc'h F, Zanta MA et al (1995) A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci U S A 92:7297-7301
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
-
32
-
-
77249179341
-
Gene expression in lung and liver after intravenous infusion of polyethyleneimine complexes and hydrodynamic delivery of sleeping beauty transposons
-
Hackett PB, Podetz-Petersen KM, Bell JB et al (2010) Gene expression in lung and liver after intravenous infusion of polyethyleneimine complexes and hydrodynamic delivery of sleeping beauty transposons. Hum Gene Ther 21(2): 210-20
-
(2010)
Hum Gene Ther
, vol.21
, Issue.2
, pp. 210-220
-
-
Hackett, P.B.1
Podetz-Petersen, K.M.2
Bell, J.B.3
-
33
-
-
0035158758
-
Prolonged organ retention and safety of plasmid DNA administered in polyethylenimine complexes
-
Oh YK, Kim JP, Yoon H et al (2001) Prolonged organ retention and safety of plasmid DNA administered in polyethylenimine complexes. Gene Ther 8:1587-1592
-
(2001)
Gene Ther
, vol.8
, pp. 1587-1592
-
-
Oh, Y.K.1
Kim, J.P.2
Yoon, H.3
-
34
-
-
0029834562
-
Evaluation of promoter strength for hepatic gene expression in vivo following adenovirusmediated gene transfer
-
Guo ZS, Wang LH, Eisensmith RC et al (1996) Evaluation of promoter strength for hepatic gene expression in vivo following adenovirusmediated gene transfer. Gene Ther 3:802-810
-
(1996)
Gene Ther
, vol.3
, pp. 802-810
-
-
Guo, Z.S.1
Wang, L.H.2
Eisensmith, R.C.3
-
35
-
-
0022371467
-
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
-
Boshart M, Weber F, Jahn G et al (1985) A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41:521-530
-
(1985)
Cell
, vol.41
, pp. 521-530
-
-
Boshart, M.1
Weber, F.2
Jahn, G.3
-
36
-
-
0029131526
-
Increasing binding of a transcription factor immediately downstream of the cap site of a cytomegalovirus gene represses expression
-
Zhang XY, Ni YS, Saifudeen Z et al (1995) Increasing binding of a transcription factor immediately downstream of the cap site of a cytomegalovirus gene represses expression. Nucleic Acids Res 23:3026-3033
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3026-3033
-
-
Zhang, X.Y.1
Ni, Y.S.2
Saifudeen, Z.3
-
37
-
-
0026516795
-
Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line
-
Sinclair JH, Baillie J, Bryant LA et al (1992) Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line. J Gen Virol 73(Pt 2):433-435
-
(1992)
J Gen Virol
, vol.73
, Issue.PART. 2
, pp. 433-435
-
-
Sinclair, J.H.1
Baillie, J.2
Bryant, L.A.3
-
38
-
-
0035166381
-
Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter
-
Gill DR, Smyth SE, Goddard CA et al (2001) Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter. Gene Ther 8:1539-1546
-
(2001)
Gene Ther
, vol.8
, pp. 1539-1546
-
-
Gill, D.R.1
Smyth, S.E.2
Goddard, C.A.3
-
39
-
-
0029872366
-
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice
-
Schorpp M, Jager R, Schellander K et al (1996) The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. Nucleic Acids Res 24:1787-1788
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 1787-1788
-
-
Schorpp, M.1
Jager, R.2
Schellander, K.3
-
40
-
-
0034921775
-
High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter
-
Yew NS, Przybylska M, Ziegler RJ et al (2001) High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter. Mol Ther 4:75-82
-
(2001)
Mol Ther
, vol.4
, pp. 75-82
-
-
Yew, N.S.1
Przybylska, M.2
Ziegler, R.J.3
-
41
-
-
0037443026
-
Nuclear RNA export
-
Cullen BR (2003) Nuclear RNA export. J Cell Sci 116:587-597
-
(2003)
J Cell Sci
, vol.116
, pp. 587-597
-
-
Cullen, B.R.1
-
42
-
-
0023790358
-
Comparison of intron-dependent and intron-independent gene expression
-
Buchman AR, Berg P (1988) Comparison of intron-dependent and intron-independent gene expression. Mol Cell Biol 8:4395-4405
-
(1988)
Mol Cell Biol
, vol.8
, pp. 4395-4405
-
-
Buchman, A.R.1
Berg, P.2
-
43
-
-
0027424119
-
A novel hepatitis B virus (HBV) genetic element with Rev response element-like properties that is essential for expression of HBV gene products
-
Huang J, Liang TJ (1993) A novel hepatitis B virus (HBV) genetic element with Rev response element-like properties that is essential for expression of HBV gene products. Mol Cell Biol 13:7476-7486
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7476-7486
-
-
Huang, J.1
Liang, T.J.2
-
44
-
-
0031950572
-
Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element
-
Donello JE, Loeb JE, Hope TJ (1998) Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element. J Virol 72:5085-5092
-
(1998)
J Virol
, vol.72
, pp. 5085-5092
-
-
Donello, J.E.1
Loeb, J.E.2
Hope, T.J.3
-
45
-
-
0033980073
-
The role of CpG motifs in innate immunity
-
Krieg AM (2000) The role of CpG motifs in innate immunity. Curr Opin Immunol 12:35-43
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 35-43
-
-
Krieg, A.M.1
-
46
-
-
39849089752
-
Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation
-
Chen ZY, Riu E, He CY et al (2008) Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation. Mol Ther 16: 548-556
-
(2008)
Mol Ther
, vol.16
, pp. 548-556
-
-
Chen, Z.Y.1
Riu, E.2
He, C.Y.3
-
47
-
-
0033585425
-
Contribution of plasmid DNA to in fl ammation in the lung after administration of cationic lipid: PDNA complexes
-
Yew NS, Wang KX, Przybylska M et al (1999) Contribution of plasmid DNA to in fl ammation in the lung after administration of cationic lipid: pDNA complexes. Hum Gene Ther 10: 223-234
-
(1999)
Hum Gene Ther
, vol.10
, pp. 223-234
-
-
Yew, N.S.1
Wang, K.X.2
Przybylska, M.3
-
48
-
-
79955705789
-
Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver
-
Argyros O, Wong SP, Fedonidis C et al (2011) Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver. J Mol Med 89:515-29
-
(2011)
J Mol Med
, vol.89
, pp. 515-529
-
-
Argyros, O.1
Wong, S.P.2
Fedonidis, C.3
-
49
-
-
60449098993
-
Progress and prospects: The design and production of plasmid vectors
-
Gill D, Pringle I, Hyde SC (2009) Progress and prospects: the design and production of plasmid vectors. Gene Ther 16:165-171
-
(2009)
Gene Ther
, vol.16
, pp. 165-171
-
-
Gill, D.1
Pringle, I.2
Hyde, S.C.3
-
50
-
-
68649119307
-
Strategies for the episomal modi fi cation of cells
-
Wong SP, Argyros O, Coutelle C et al (2009) Strategies for the episomal modi fi cation of cells. Curr Opin Mol Ther 11:433-441
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 433-441
-
-
Wong, S.P.1
Argyros, O.2
Coutelle, C.3
-
51
-
-
0038814164
-
Recent advances in immunostimulatory CpG oligonucleotides
-
Rothenfusser S, Tuma E, Wagner M et al (2003) Recent advances in immunostimulatory CpG oligonucleotides. Curr Opin Mol Ther 5: 98-106
-
(2003)
Curr Opin Mol Ther
, vol.5
, pp. 98-106
-
-
Rothenfusser, S.1
Tuma, E.2
Wagner, M.3
-
52
-
-
0029618309
-
The structural basis of nuclear function
-
Jackson DA, Cook PR (1995) The structural basis of nuclear function. Int Rev Cytol 162A: 125-149
-
(1995)
Int Rev Cytol
, vol.162 A
, pp. 125-149
-
-
Jackson, D.A.1
Cook, P.R.2
-
53
-
-
0033555686
-
A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells
-
Piechaczek C, Fetzer C, Baiker A et al (1999) A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells. Nucleic Acids Res 27:426-428
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 426-428
-
-
Piechaczek, C.1
Fetzer, C.2
Baiker, A.3
-
54
-
-
3042730820
-
Expression of a transgene encoded on a nonviral episomal vector is not subject to epigenetic silencing by cytosine methylation
-
Jenke AC, Scinteie MF, Stehle IM et al (2004) Expression of a transgene encoded on a nonviral episomal vector is not subject to epigenetic silencing by cytosine methylation. Mol Biol Rep 31:85-90
-
(2004)
Mol Biol Rep
, vol.31
, pp. 85-90
-
-
Jenke, A.C.1
Scinteie, M.F.2
Stehle, I.M.3
-
55
-
-
0036246051
-
An episomally replicating vector binds to the nuclear matrix protein SAF-A in vivo
-
Jenke BH, Fetzer CP, Stehle IM et al (2002) An episomally replicating vector binds to the nuclear matrix protein SAF-A in vivo. EMBO Rep 3:349-354
-
(2002)
EMBO Rep
, vol.3
, pp. 349-354
-
-
Jenke, B.H.1
Fetzer, C.P.2
Stehle, I.M.3
-
56
-
-
29244487057
-
Gene transfer into human hematopoietic progenitor cells with an episomal vector carrying an S/MAR element
-
Papapetrou EP, Ziros PG, Micheva ID et al (2006) Gene transfer into human hematopoietic progenitor cells with an episomal vector carrying an S/MAR element. Gene Ther 13: 40-51
-
(2006)
Gene Ther
, vol.13
, pp. 40-51
-
-
Papapetrou, E.P.1
Ziros, P.G.2
Micheva, I.D.3
-
57
-
-
34548348766
-
Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells
-
Girod PA, Nguyen DQ, Calabrese D et al (2007) Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells. Nat Methods 4: 747-753
-
(2007)
Nat Methods
, vol.4
, pp. 747-753
-
-
Girod, P.A.1
Nguyen, D.Q.2
Calabrese, D.3
-
58
-
-
0024948946
-
A nuclear DNA attachment element mediates elevated and position-independent gene activity
-
Stief A, Winter DM, Stratling WH et al (1989) A nuclear DNA attachment element mediates elevated and position-independent gene activity. Nature 341:343-345
-
(1989)
Nature
, vol.341
, pp. 343-345
-
-
Stief, A.1
Winter, D.M.2
Stratling, W.H.3
-
59
-
-
0026697332
-
Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate
-
Klehr D, Schlake T, Maass K et al (1992) Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate. Biochemistry 31:3222-3229
-
(1992)
Biochemistry
, vol.31
, pp. 3222-3229
-
-
Klehr, D.1
Schlake, T.2
Maass, K.3
-
60
-
-
0025145628
-
Tissue speci fi c and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice
-
Bonifer C, Vidal M, Grosveld F et al (1990) Tissue speci fi c and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice. EMBO J 9:2843-2848
-
(1990)
EMBO J
, vol.9
, pp. 2843-2848
-
-
Bonifer, C.1
Vidal, M.2
Grosveld, F.3
-
61
-
-
0026651977
-
Matrix-attachment regions can impart position-independent regulation of a tissuespeci fi c gene in transgenic mice
-
McKnight RA, Shamay A, Sankaran L et al (1992) Matrix-attachment regions can impart position-independent regulation of a tissuespeci fi c gene in transgenic mice. Proc Natl Acad Sci U S A 89:6943-6947
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 6943-6947
-
-
McKnight, R.A.1
Shamay, A.2
Sankaran, L.3
-
62
-
-
0028328632
-
B cell-speci fi c demethylation: A novel role for the intronic kappa chain enhancer sequence
-
Lichtenstein M, Keini G, Cedar H et al (1994) B cell-speci fi c demethylation: a novel role for the intronic kappa chain enhancer sequence. Cell 76:913-923
-
(1994)
Cell
, vol.76
, pp. 913-923
-
-
Lichtenstein, M.1
Keini, G.2
Cedar, H.3
-
63
-
-
0032709770
-
Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions
-
Forrester WC, Fernandez LA, Grosschedl R (1999) Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions. Genes Dev 13:3003-3014
-
(1999)
Genes Dev
, vol.13
, pp. 3003-3014
-
-
Forrester, W.C.1
Fernandez, L.A.2
Grosschedl, R.3
-
64
-
-
84921582173
-
Use of scaffold/matrix-attachment regions for protein production
-
Elsevier Science B.V. Makrides SC (Ed.)
-
Girod PA, Mermod N (2003) Use of scaffold/matrix-attachment regions for protein production. Elsevier Science B.V. Makrides SC (Ed.) Gene Transfer and Expression in Mammalian Cells, Chapter 10
-
(2003)
Gene Transfer and Expression in Mammalian Cells
, pp. 10
-
-
Girod, P.A.1
Mermod, N.2
-
65
-
-
0028988485
-
Positionindependant transgene expression mediated by boundary elements from the apoliprotein B chromatin domain
-
Kalos M, Fournier R (1995) Positionindependant transgene expression mediated by boundary elements from the apoliprotein B chromatin domain. Mol Cell Biol 15:198-207
-
(1995)
Mol Cell Biol
, vol.15
, pp. 198-207
-
-
Kalos, M.1
Fournier, R.2
-
67
-
-
59249084751
-
Sustained transgene expression using MAR elements
-
Harraghy N, Gaussin A, Mermod N (2008) Sustained transgene expression using MAR elements. Curr Gene Ther 8:353-366
-
(2008)
Curr Gene Ther
, vol.8
, pp. 353-366
-
-
Harraghy, N.1
Gaussin, A.2
Mermod, N.3
-
68
-
-
0025181252
-
Hierarchical binding of DNA fragments derived from scaffold-attached regions: Correlation of properties in vitro and function in vivo
-
Mielke C, Kohwi Y, Kohwi-Shigematsu T et al (1990) Hierarchical binding of DNA fragments derived from scaffold-attached regions: correlation of properties in vitro and function in vivo. Biochemistry 29:7475-7485
-
(1990)
Biochemistry
, vol.29
, pp. 7475-7485
-
-
Mielke, C.1
Kohwi, Y.2
Kohwi-Shigematsu, T.3
-
69
-
-
0030138749
-
High-level transgene expression in plant cells: Effects of a strong scaffold attachment region from tobacco
-
Allen GC, Hall G Jr, Michalowski S et al (1996) High-level transgene expression in plant cells: effects of a strong scaffold attachment region from tobacco. Plant Cell 8:899-913
-
(1996)
Plant Cell
, vol.8
, pp. 899-913
-
-
Allen, G.C.1
Hall Jr., G.2
Michalowski, S.3
-
70
-
-
34548382578
-
Establishment and mitotic stability of an extrachromosomal mammalian replicon
-
Stehle IM, Postberg J, Rupprecht S et al (2007) Establishment and mitotic stability of an extrachromosomal mammalian replicon. BMC Cell Biol 8:33
-
(2007)
BMC Cell Biol
, vol.8
, pp. 33
-
-
Stehle, I.M.1
Postberg, J.2
Rupprecht, S.3
-
71
-
-
0035933760
-
An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy
-
Bigger BW, Tolmachov O, Collombet JM et al (2001) An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy. J Biol Chem 276:23018-23027
-
(2001)
J Biol Chem
, vol.276
, pp. 23018-23027
-
-
Bigger, B.W.1
Tolmachov, O.2
Collombet, J.M.3
-
72
-
-
0041315884
-
Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
-
Chen ZY, He CY, Ehrhardt A et al (2003) Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Mol Ther 8:495-500
-
(2003)
Mol Ther
, vol.8
, pp. 495-500
-
-
Chen, Z.Y.1
He, C.Y.2
Ehrhardt, A.3
-
73
-
-
0033023054
-
Minicircle: An improved DNA molecule for in vitro and in vivo gene transfer
-
Darquet AM, Rangara R, Kreiss P et al (1999) Minicircle: an improved DNA molecule for in vitro and in vivo gene transfer. Gene Ther 6: 209-218
-
(1999)
Gene Ther
, vol.6
, pp. 209-218
-
-
Darquet, A.M.1
Rangara, R.2
Kreiss, P.3
-
74
-
-
38349130849
-
Replicating minicircles: Generation of nonviral episomes for the ef fi cient modi fi cation of dividing cells
-
Nehlsen K, Broll S, Bode J (2006) Replicating minicircles: generation of nonviral episomes for the ef fi cient modi fi cation of dividing cells. Gene Ther Mol Biol 10:233-244
-
(2006)
Gene Ther Mol Biol
, vol.10
, pp. 233-244
-
-
Nehlsen, K.1
Broll, S.2
Bode, J.3
-
75
-
-
34250739823
-
Histone modi fi cations are associated with the persistence or silencing of vector-mediated transgene expression in vivo
-
Riu E, Chen ZY, Xu H et al (2007) Histone modi fi cations are associated with the persistence or silencing of vector-mediated transgene expression in vivo. Mol Ther 15:1348-1355
-
(2007)
Mol Ther
, vol.15
, pp. 1348-1355
-
-
Riu, E.1
Chen, Z.Y.2
Xu, H.3
-
76
-
-
33745275571
-
Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo
-
Vaysse L, Gregory LG, Harbottle RP et al (2006) Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo. J Gene Med 8:754-763
-
(2006)
J Gene Med
, vol.8
, pp. 754-763
-
-
Vaysse, L.1
Gregory, L.G.2
Harbottle, R.P.3
-
77
-
-
50649102345
-
Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene
-
Zhang X, Epperly MW, Kay MA et al (2008) Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene. Hum Gene Ther 19:820-826
-
(2008)
Hum Gene Ther
, vol.19
, pp. 820-826
-
-
Zhang, X.1
Epperly, M.W.2
Kay, M.A.3
-
78
-
-
37549056600
-
Ef fi cient expression of vascular endothelial growth factor using minicircle DNA for angiogenic gene therapy
-
Chang CW, Christensen LV, Lee M et al (2008) Ef fi cient expression of vascular endothelial growth factor using minicircle DNA for angiogenic gene therapy. J Control Release 125: 155-163
-
(2008)
J Control Release
, vol.125
, pp. 155-163
-
-
Chang, C.W.1
Christensen, L.V.2
Lee, M.3
-
79
-
-
0026537332
-
Lambda Int protein bridges between higher order complexes at two distant chromosomal foci attL and attR
-
Kim S, Landy A (1992) Lambda Int protein bridges between higher order complexes at two distant chromosomal foci attL and attR. Science 256:198-203
-
(1992)
Science
, vol.256
, pp. 198-203
-
-
Kim, S.1
Landy, A.2
-
82
-
-
0033745097
-
Control of directionality in the site-speci fi c recombination system of the Streptomyces phage phiC31
-
Thorpe HM, Wilson SE, Smith MC (2000) Control of directionality in the site-speci fi c recombination system of the Streptomyces phage phiC31. Mol Microbiol 38:232-241
-
(2000)
Mol Microbiol
, vol.38
, pp. 232-241
-
-
Thorpe, H.M.1
Wilson, S.E.2
Smith, M.C.3
-
83
-
-
0034705105
-
A phage integrase directs ef fi cient sitespeci fi c integration in human cells
-
Groth AC, Olivares EC, Thyagarajan B et al (2000) A phage integrase directs ef fi cient sitespeci fi c integration in human cells. Proc Natl Acad Sci U S A 97:5995-6000
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5995-6000
-
-
Groth, A.C.1
Olivares, E.C.2
Thyagarajan, B.3
-
84
-
-
27344439351
-
Complete and persistent phenotypic correction of phenylketonuria in mice by site-speci fi c genome integration of murine phenylalanine hydroxylase cDNA
-
Chen L, Woo SL (2005) Complete and persistent phenotypic correction of phenylketonuria in mice by site-speci fi c genome integration of murine phenylalanine hydroxylase cDNA. Proc Natl Acad Sci U S A 102:15581-15586
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15581-15586
-
-
Chen, L.1
Woo, S.L.2
-
86
-
-
0029860719
-
Different thermostabilities of FLP and Cre recombinases: Implications for applied sitespeci fi c recombination
-
Buchholz F, Ringrose L, Angrand PO et al (1996) Different thermostabilities of FLP and Cre recombinases: implications for applied sitespeci fi c recombination. Nucl Acids Res 24: 4256-4262
-
(1996)
Nucl Acids Res
, vol.24
, pp. 4256-4262
-
-
Buchholz, F.1
Ringrose, L.2
Angrand, P.O.3
-
87
-
-
0029981092
-
Evidence for the role of proteoglycans in cation-mediated gene transfer
-
Mislick KA, Baldeschwieler JD (1996) Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci U S A 93:12349-12354
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 12349-12354
-
-
Mislick, K.A.1
Baldeschwieler, J.D.2
-
88
-
-
0038442898
-
Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA)
-
Gharwan H, Wightman L, Kircheis R et al (2003) Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA). Gene Ther 10: 810-817
-
(2003)
Gene Ther
, vol.10
, pp. 810-817
-
-
Gharwan, H.1
Wightman, L.2
Kircheis, R.3
-
89
-
-
0032571392
-
Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
-
Pollard H, Remy JS, Loussouarn G et al (1998) Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem 273: 7507-7511
-
(1998)
J Biol Chem
, vol.273
, pp. 7507-7511
-
-
Pollard, H.1
Remy, J.S.2
Loussouarn, G.3
-
90
-
-
79955064879
-
Systemic gene transfer of polyethylenimine (PEI)-plasmid DNA complexes to neonatal mice
-
Wong SP, Argyros O, Howe SJ et al (2010) Systemic gene transfer of polyethylenimine (PEI)-plasmid DNA complexes to neonatal mice. J Control Release 150:298-306
-
(2010)
J Control Release
, vol.150
, pp. 298-306
-
-
Wong, S.P.1
Argyros, O.2
Howe, S.J.3
-
91
-
-
0031714427
-
Chitosan: A unique polysaccharide for drug delivery
-
Felt O, Buri P, Gurny R (1998) Chitosan: a unique polysaccharide for drug delivery. Drug Dev Ind Pharm 24:979-993
-
(1998)
Drug Dev Ind Pharm
, vol.24
, pp. 979-993
-
-
Felt, O.1
Buri, P.2
Gurny, R.3
-
92
-
-
0035804770
-
Ef fi cient in utero gene transfer system to the developing mouse brain using electroporation: Visualization of neuronal migration in the developing cortex
-
Tabata H, Nakajima K (2001) Ef fi cient in utero gene transfer system to the developing mouse brain using electroporation: visualization of neuronal migration in the developing cortex. Neuroscience 103:865-872
-
(2001)
Neuroscience
, vol.103
, pp. 865-872
-
-
Tabata, H.1
Nakajima, K.2
-
93
-
-
0035584249
-
Ef fi cient gene transfer into the embryonic mouse brain using in vivo electroporation
-
Saito T, Nakatsuji N (2001) Ef fi cient gene transfer into the embryonic mouse brain using in vivo electroporation. Dev Biol 240: 237-246
-
(2001)
Dev Biol
, vol.240
, pp. 237-246
-
-
Saito, T.1
Nakatsuji, N.2
-
94
-
-
4744364706
-
Nonviral gene transfer to surface skin of midgestational murine embryos by intraamniotic injection and subsequent electroporation
-
Sato M, Tanigawa M, Kikuchi N (2004) Nonviral gene transfer to surface skin of midgestational murine embryos by intraamniotic injection and subsequent electroporation. Mol Reprod Dev 69:268-277
-
(2004)
Mol Reprod Dev
, vol.69
, pp. 268-277
-
-
Sato, M.1
Tanigawa, M.2
Kikuchi, N.3
-
95
-
-
36248946660
-
Gene delivery into mouse retinal ganglion cells by in utero electroporation
-
Garcia-Frigola C, Carreres MI, Vegar C et al (2007) Gene delivery into mouse retinal ganglion cells by in utero electroporation. BMC Dev Biol 7:103
-
(2007)
BMC Dev Biol
, vol.7
, pp. 103
-
-
Garcia-Frigola, C.1
Carreres, M.I.2
Vegar, C.3
-
96
-
-
78650028269
-
A robust system for production of minicircle DNA vectors
-
Kay MA, He CY, Chen ZY (2010) A robust system for production of minicircle DNA vectors. Nat Biotechnol 28:1287-1289
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1287-1289
-
-
Kay, M.A.1
He, C.Y.2
Chen, Z.Y.3
-
98
-
-
81155144647
-
In utero gene delivery using Chitosan-DNA nanoparticles in mice
-
Yang PT, Hoang L, Jia WW et al (2011) In utero gene delivery using Chitosan-DNA nanoparticles in mice. J Surg Res 171(2):691-9
-
(2011)
J Surg Res
, vol.171
, Issue.2
, pp. 691-699
-
-
Yang, P.T.1
Hoang, L.2
Jia, W.W.3
-
99
-
-
24644507123
-
Gastric emptying cycles in the human fetus
-
Sase M, Miwa I, Sumie M et al (2005) Gastric emptying cycles in the human fetus. Am J Obstet Gynecol 193:1000-1004
-
(2005)
Am J Obstet Gynecol
, vol.193
, pp. 1000-1004
-
-
Sase, M.1
Miwa, I.2
Sumie, M.3
|