Prolonged organ retention and safety of plasmid DNA administered in polyethylenimine complexes

Gene Therapy

Volumn 8, Issue 20, 2001, Pages 1587-1592

  Oh, Y K ^a   Kim, J P ^a   Yoon, H ^a   Kim, J M ^b   Yang, J S ^c   Kim, C K ^d  

^a CHA University   (South Korea)

^b Hanyang University   (South Korea)

^c Korea Food and Drug Administration   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

Biodistribution; Competitive polymerase chain reaction; DNA; Pharmacokinetics; Polyethylenimine; Safety

Indexed keywords

DNA; MESSENGER RNA; PLASMID DNA; POLYETHYLENEIMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOMEGALOVIRUS; DELETION MUTANT; DNA VECTOR; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG SAFETY; GENE EXPRESSION; GENE TRANSFER; GENETIC MODEL; HEPATITIS; HISTOLOGY; LIVER; LUNG; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; STANDARD;

ANIMALS; AREA UNDER CURVE; CYTOMEGALOVIRUS; DNA; FEMALE; GENETIC VECTORS; INFLAMMATION; INJECTIONS, INTRAVENOUS; KIDNEY; LIVER; LUNG; MICE; OVARY; POLYETHYLENEIMINE; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; VACCINES, DNA;

EID: 0035158758     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301516     Document Type: Article

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