Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression

Oncotarget

Volumn 6, Issue 17, 2015, Pages 15524-15539

  Mohammed, Altaf ^a   Janakiram, Naveena B ^a   Madka, Venkateshwar ^a   Brewer, Misty ^a   Ritchie, Rebekah L ^a   Lightfoot, Stan ^a   Kumar, Gaurav ^a   Sadeghi, Michael ^a   Patlolla, Jagan Mohan R ^a   Yamada, Hiroshi Y ^a   Cruz Monserrate, Zobeida ^b   May, Randal ^a   Houchen, Courtney W ^a   Steele, Vernon E ^c   Rao, Chinthalapally V ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cancer stem cells; Dual COX 5 LOX inhibition; Inflammation; P48Cre + LSL KrasG12D + mice; Pancreatic cancer

Indexed keywords

ANTIINFLAMMATORY AGENT; ARACHIDONIC ACID; CERULETIDE; CYCLOOXYGENASE 2; DCAMKL1 PROTEIN, MOUSE; LICOFELONE; LIPOXYGENASE INHIBITOR; MICRORNA; PROTEIN SERINE THREONINE KINASE; PTGS2 PROTEIN, MOUSE; PYRROLE DERIVATIVE;

ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CANCER STEM CELL; CARCINOMA IN SITU; CARCINOMA, PANCREATIC DUCTAL; CELL PROLIFERATION; CHEMICALLY INDUCED; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; PANCREATIC NEOPLASMS; PANCREATITIS; PATHOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; ARACHIDONIC ACID; CARCINOMA IN SITU; CARCINOMA, PANCREATIC DUCTAL; CELL PROLIFERATION; CERULETIDE; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; LIPOXYGENASE INHIBITORS; MICE; MICE, KNOCKOUT; MICRORNAS; NEOPLASTIC STEM CELLS; PANCREATIC NEOPLASMS; PANCREATITIS; PROTEIN-SERINE-THREONINE KINASES; PYRROLES;

EID: 84934343399     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3499     Document Type: Article

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