메뉴 건너뛰기




Volumn 6, Issue MAY, 2015, Pages

A systematic approach to identify markers of distinctly activated human macrophages

Author keywords

Activation markers; Human macrophages; Integrated fluidic circuit RT PCR; Macrophage polarization; Microarray

Indexed keywords

BIOLOGICAL MARKER; CCL18; CD163 ANTIGEN; CHEMOKINE; CXCL9 CHEMOKINE; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IDO1; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 4; INTERFERON REGULATORY FACTOR 5; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 23P19; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 4; MRC1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 84934279386     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00253     Document Type: Article
Times cited : (28)

References (40)
  • 1
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation
    • Stein M, Keshav S, Harris N, Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med (1992) 176:287-92. doi:10.1084/jem.176.1.287
    • (1992) J Exp Med , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 2
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol (2002) 23:549-55. doi:10.1016/S1471-4906(02)02302-5
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 3
  • 4
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 8:958-69. doi:10.1038/nri2448
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 5
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol (2004) 25:677-86. doi:10.1016/j.it.2004.09.015
    • (2004) Trends Immunol , vol.25 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 7
    • 77954507872 scopus 로고    scopus 로고
    • CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages
    • Gleissner CA, Shaked I, Little KM, Ley K. CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages. J Immunol (2010) 184:4810-8. doi:10.4049/jimmunol.0901368
    • (2010) J Immunol , vol.184 , pp. 4810-4818
    • Gleissner, C.A.1    Shaked, I.2    Little, K.M.3    Ley, K.4
  • 8
    • 84877796414 scopus 로고    scopus 로고
    • IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids
    • Zizzo G, Cohen PL. IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids. J Immunol (2013) 190:5237-46. doi:10.4049/jimmunol.1203017
    • (2013) J Immunol , vol.190 , pp. 5237-5246
    • Zizzo, G.1    Cohen, P.L.2
  • 9
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: nomenclature and experimental guidelines
    • Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity (2014) 41:14-20. doi:10.1016/j.immuni.2014.06.008
    • (2014) Immunity , vol.41 , pp. 14-20
    • Murray, P.J.1    Allen, J.E.2    Biswas, S.K.3    Fisher, E.A.4    Gilroy, D.W.5    Goerdt, S.6
  • 10
    • 80052447249 scopus 로고    scopus 로고
    • Varying effects of different beta-glucans on the maturation of porcine monocyte-derived dendritic cells
    • Sonck E, Devriendt B, Goddeeris B, Cox E. Varying effects of different beta-glucans on the maturation of porcine monocyte-derived dendritic cells. Clin Vaccine Immunol (2011) 18:1441-6. doi:10.1128/CVI.00080-11
    • (2011) Clin Vaccine Immunol , vol.18 , pp. 1441-1446
    • Sonck, E.1    Devriendt, B.2    Goddeeris, B.3    Cox, E.4
  • 11
    • 0142149108 scopus 로고    scopus 로고
    • Endotoxin contamination of ovalbumin suppresses murine immunologic responses and development of airway hyper-reactivity
    • Watanabe J, Miyazaki Y, Zimmerman GA, Albertine KH, McIntyre TM. Endotoxin contamination of ovalbumin suppresses murine immunologic responses and development of airway hyper-reactivity. J Biol Chem (2003) 278:42361-8. doi:10.1074/jbc. M307752200
    • (2003) J Biol Chem , vol.278 , pp. 42361-42368
    • Watanabe, J.1    Miyazaki, Y.2    Zimmerman, G.A.3    Albertine, K.H.4    McIntyre, T.M.5
  • 12
    • 40049088602 scopus 로고    scopus 로고
    • The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages
    • Allavena P, Sica A, Solinas G, Porta C, Mantovani A. The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit Rev Oncol Hematol (2008) 66:1-9. doi:10.1016/j.critrevonc.2007.07.004
    • (2008) Crit Rev Oncol Hematol , vol.66 , pp. 1-9
    • Allavena, P.1    Sica, A.2    Solinas, G.3    Porta, C.4    Mantovani, A.5
  • 13
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature (2002) 420:860-7. doi:10.1038/nature01322
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 14
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer (2004) 4:71-8. doi:10.1038/nrc1256
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 15
    • 84897933309 scopus 로고    scopus 로고
    • Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues
    • Van Overmeire E, Laoui D, Keirsse J, Van Ginderachter JA, Sarukhan A. Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues. Front Immunol (2014) 5:127. doi:10.3389/fimmu.2014.00127
    • (2014) Front Immunol , vol.5 , pp. 127
    • Van Overmeire, E.1    Laoui, D.2    Keirsse, J.3    Van Ginderachter, J.A.4    Sarukhan, A.5
  • 16
    • 21244443731 scopus 로고    scopus 로고
    • Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
    • Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol (2005) 175:342-9. doi:10.4049/jimmunol.175.1.342
    • (2005) J Immunol , vol.175 , pp. 342-349
    • Stout, R.D.1    Jiang, C.2    Matta, B.3    Tietzel, I.4    Watkins, S.K.5    Suttles, J.6
  • 17
    • 4344706372 scopus 로고    scopus 로고
    • Functional plasticity of macrophages: reversible adaptation to changing microenvironments
    • Stout RD, Suttles J. Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J Leukoc Biol (2004) 76:509-13. doi:10.1189/jlb.0504272
    • (2004) J Leukoc Biol , vol.76 , pp. 509-513
    • Stout, R.D.1    Suttles, J.2
  • 18
    • 84887561907 scopus 로고    scopus 로고
    • Low-dose irradiation programs macrophage differentiation to an iNOS(+)/M1 phenotype that orchestrates effective T cell immunotherapy
    • Klug F, Prakash H, Huber PE, Seibel T, Bender N, Halama N, et al. Low-dose irradiation programs macrophage differentiation to an iNOS(+)/M1 phenotype that orchestrates effective T cell immunotherapy. Cancer Cell (2013) 24:589-602. doi:10.1016/j.ccr.2013.09.014
    • (2013) Cancer Cell , vol.24 , pp. 589-602
    • Klug, F.1    Prakash, H.2    Huber, P.E.3    Seibel, T.4    Bender, N.5    Halama, N.6
  • 19
    • 84893502903 scopus 로고    scopus 로고
    • Sensitizing protective tumor microenvironments to antibody-mediated therapy
    • Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, et al. Sensitizing protective tumor microenvironments to antibody-mediated therapy. Cell (2014) 156:590-602. doi:10.1016/j.cell.2013.12.041
    • (2014) Cell , vol.156 , pp. 590-602
    • Pallasch, C.P.1    Leskov, I.2    Braun, C.J.3    Vorholt, D.4    Drake, A.5    Soto-Feliciano, Y.M.6
  • 20
    • 84887481716 scopus 로고    scopus 로고
    • CSF-1R inhibition alters macrophage polarization and blocks glioma progression
    • Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, et al. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat Med (2013) 19:1264-72. doi:10.1038/nm.3337
    • (2013) Nat Med , vol.19 , pp. 1264-1272
    • Pyonteck, S.M.1    Akkari, L.2    Schuhmacher, A.J.3    Bowman, R.L.4    Sevenich, L.5    Quail, D.F.6
  • 21
    • 84902546715 scopus 로고    scopus 로고
    • Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
    • Ries CH, Cannarile MA, Hoves S, Benz J, Wartha K, Runza V, et al. Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. Cancer Cell (2014) 25:846-59. doi:10.1016/j.ccr.2014.05.016
    • (2014) Cancer Cell , vol.25 , pp. 846-859
    • Ries, C.H.1    Cannarile, M.A.2    Hoves, S.3    Benz, J.4    Wartha, K.5    Runza, V.6
  • 22
    • 33746215136 scopus 로고    scopus 로고
    • Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene
    • Bosco MC, Puppo M, Santangelo C, Anfosso L, Pfeffer U, Fardin P, et al. Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene. J Immunol (2006) 177:1941-55. doi:10.4049/jimmunol.177.3.1941
    • (2006) J Immunol , vol.177 , pp. 1941-1955
    • Bosco, M.C.1    Puppo, M.2    Santangelo, C.3    Anfosso, L.4    Pfeffer, U.5    Fardin, P.6
  • 24
    • 46749137580 scopus 로고    scopus 로고
    • Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3
    • Chang YC, Chen TC, Lee CT, Yang CY, Wang HW, Wang CC, et al. Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3. Blood (2008) 111:5054-63. doi:10.1182/blood-2007-12-130609
    • (2008) Blood , vol.111 , pp. 5054-5063
    • Chang, Y.C.1    Chen, T.C.2    Lee, C.T.3    Yang, C.Y.4    Wang, H.W.5    Wang, C.C.6
  • 25
    • 24744439698 scopus 로고    scopus 로고
    • IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1
    • Hu X, Park-Min KH, Ho HH, Ivashkiv LB. IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1. J Immunol (2005) 175:3637-47. doi:10.4049/jimmunol.175.6.3637
    • (2005) J Immunol , vol.175 , pp. 3637-3647
    • Hu, X.1    Park-Min, K.H.2    Ho, H.H.3    Ivashkiv, L.B.4
  • 26
    • 59649091219 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages
    • Irvine KM, Andrews MR, Fernandez-Rojo MA, Schroder K, Burns CJ, Su S, et al. Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages. J Leukoc Biol (2009) 85:278-88. doi:10.1189/jlb.0808497
    • (2009) J Leukoc Biol , vol.85 , pp. 278-288
    • Irvine, K.M.1    Andrews, M.R.2    Fernandez-Rojo, M.A.3    Schroder, K.4    Burns, C.J.5    Su, S.6
  • 27
    • 45349109007 scopus 로고    scopus 로고
    • Identification of interleukin-1 and interleukin-6-responsive genes in human monocyte-derived macrophages using microarrays
    • Jura J, Wegrzyn P, Korostynski M, Guzik K, Oczko-Wojciechowska M, Jarzab M, et al. Identification of interleukin-1 and interleukin-6-responsive genes in human monocyte-derived macrophages using microarrays. Biochim Biophys Acta (2008) 1779:383-9. doi:10.1016/j.bbagrm.2008.04.006
    • (2008) Biochim Biophys Acta , vol.1779 , pp. 383-389
    • Jura, J.1    Wegrzyn, P.2    Korostynski, M.3    Guzik, K.4    Oczko-Wojciechowska, M.5    Jarzab, M.6
  • 28
    • 0036533579 scopus 로고    scopus 로고
    • Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes
    • Locati M, Deuschle U, Massardi ML, Martinez FO, Sironi M, Sozzani S, et al. Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes. J Immunol (2002) 168:3557-62. doi:10.4049/jimmunol.168.7.3557
    • (2002) J Immunol , vol.168 , pp. 3557-3562
    • Locati, M.1    Deuschle, U.2    Massardi, M.L.3    Martinez, F.O.4    Sironi, M.5    Sozzani, S.6
  • 29
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
    • Martinez FO, Gordon S, Locati M, Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol (2006) 177:7303-11. doi:10.4049/jimmunol.177.10.7303
    • (2006) J Immunol , vol.177 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 30
    • 12144266586 scopus 로고    scopus 로고
    • Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13
    • Scotton CJ, Martinez FO, Smelt MJ, Sironi M, Locati M, Mantovani A, et al. Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13. J Immunol (2005) 174:834-45. doi:10.4049/jimmunol.174.2.834
    • (2005) J Immunol , vol.174 , pp. 834-845
    • Scotton, C.J.1    Martinez, F.O.2    Smelt, M.J.3    Sironi, M.4    Locati, M.5    Mantovani, A.6
  • 31
    • 33748855014 scopus 로고    scopus 로고
    • Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2)
    • Sironi M, Martinez FO, D'Ambrosio D, Gattorno M, Polentarutti N, Locati M, et al. Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2). J Leukoc Biol (2006) 80:342-9. doi:10.1189/jlb.1005586
    • (2006) J Leukoc Biol , vol.80 , pp. 342-349
    • Sironi, M.1    Martinez, F.O.2    D'Ambrosio, D.3    Gattorno, M.4    Polentarutti, N.5    Locati, M.6
  • 32
    • 9244249240 scopus 로고    scopus 로고
    • Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors
    • Tassiulas I, Hu X, Ho H, Kashyap Y, Paik P, Hu Y, et al. Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors. Nat Immunol (2004) 5:1181-9. doi:10.1038/ni1126
    • (2004) Nat Immunol , vol.5 , pp. 1181-1189
    • Tassiulas, I.1    Hu, X.2    Ho, H.3    Kashyap, Y.4    Paik, P.5    Hu, Y.6
  • 33
    • 84894102230 scopus 로고    scopus 로고
    • Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
    • Xue J, Schmidt SV, Sander J, Draffehn A, Krebs W, Quester I, et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity (2014) 40:274-88. doi:10.1016/j.immuni.2014.01.006
    • (2014) Immunity , vol.40 , pp. 274-288
    • Xue, J.1    Schmidt, S.V.2    Sander, J.3    Draffehn, A.4    Krebs, W.5    Quester, I.6
  • 34
    • 84887013719 scopus 로고    scopus 로고
    • TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses
    • Cohen HB, Briggs KT, Marino JP, Ravid K, Robson SC, Mosser DM. TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses. Blood (2013) 122:1935-45. doi:10.1182/blood-2013-04-496216
    • (2013) Blood , vol.122 , pp. 1935-1945
    • Cohen, H.B.1    Briggs, K.T.2    Marino, J.P.3    Ravid, K.4    Robson, S.C.5    Mosser, D.M.6
  • 35
    • 0032490575 scopus 로고    scopus 로고
    • Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I
    • Sutterwala FS, Noel GJ, Salgame P, Mosser DM. Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I. J Exp Med (1998) 188:217-22. doi:10.1084/jem.188.1.217
    • (1998) J Exp Med , vol.188 , pp. 217-222
    • Sutterwala, F.S.1    Noel, G.J.2    Salgame, P.3    Mosser, D.M.4
  • 37
    • 84868030361 scopus 로고    scopus 로고
    • Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer
    • Quatromoni JG, Eruslanov E. Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer. Am J Transl Res (2012) 4:376-89.
    • (2012) Am J Transl Res , vol.4 , pp. 376-389
    • Quatromoni, J.G.1    Eruslanov, E.2
  • 38
    • 0036658739 scopus 로고    scopus 로고
    • A novel phenotype for an activated macrophage: the type 2 activated macrophage
    • Anderson CF, Mosser DM. A novel phenotype for an activated macrophage: the type 2 activated macrophage. J Leukoc Biol (2002) 72:101-6.
    • (2002) J Leukoc Biol , vol.72 , pp. 101-106
    • Anderson, C.F.1    Mosser, D.M.2
  • 39
    • 33845398215 scopus 로고    scopus 로고
    • Biochemical and functional characterization of three activated macrophage populations
    • Edwards JP, Zhang X, Frauwirth KA, Mosser DM. Biochemical and functional characterization of three activated macrophage populations. J Leukoc Biol (2006) 80:1298-307. doi:10.1189/jlb.0406249
    • (2006) J Leukoc Biol , vol.80 , pp. 1298-1307
    • Edwards, J.P.1    Zhang, X.2    Frauwirth, K.A.3    Mosser, D.M.4
  • 40
    • 0035337139 scopus 로고    scopus 로고
    • Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors
    • Gerber JS, Mosser DM. Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors. J Immunol (2001) 166:6861-8. doi:10.4049/jimmunol.166.11.6861
    • (2001) J Immunol , vol.166 , pp. 6861-6868
    • Gerber, J.S.1    Mosser, D.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.