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Volumn 14, Issue 7, 2015, Pages 626-635

Impact of protein palmitoylation on the virulence potential of Cryptococcus neoformans

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; FUNGAL PROTEIN; RAS PROTEIN;

EID: 84934272563     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00010-15     Document Type: Article
Times cited : (17)

References (46)
  • 1
    • 61449149636 scopus 로고    scopus 로고
    • Palmitoylation cycles and regulation ofprotein function
    • Baekkeskov S, Kanaani J. 2009. Palmitoylation cycles and regulation of protein function. Mol Membr Biol 26:42-54. http://dx.doi.org/10.1080/09687680802680108
    • (2009) Mol Membr Biol , vol.26 , pp. 42-54
    • Baekkeskov, S.1    Kanaani, J.2
  • 2
    • 78650718836 scopus 로고    scopus 로고
    • The intracellular dynamicof protein palmitoylation
    • Salaun C, Greaves J, Chamberlain LH. 2010. The intracellular dynamic of protein palmitoylation. J Cell Biol 191:1229-1238. http://dx.doi.org/10.1083/jcb.201008160
    • (2010) J Cell Biol , vol.191 , pp. 1229-1238
    • Salaun, C.1    Greaves, J.2    Chamberlain, L.H.3
  • 3
    • 0037174987 scopus 로고    scopus 로고
    • Identificationof a Ras palmitoyltransferase in Saccharomyces cerevisiae
    • Lobo S, Greentree WK, Linder ME, Deschenes RJ. 2002. Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae. J Biol Chem 277:41268-41273. http://dx.doi.org/10.1074/jbc.M206573200
    • (2002) J Biol Chem , vol.277 , pp. 41268-41273
    • Lobo, S.1    Greentree, W.K.2    Linder, M.E.3    Deschenes, R.J.4
  • 4
    • 0037078323 scopus 로고    scopus 로고
    • The yeast DHHC cysteinerich domain protein Akr1p is a palmitoyl transferase
    • Roth AF, Feng Y, Chen L, Davis NG. 2002. The yeast DHHC cysteinerich domain protein Akr1p is a palmitoyl transferase. J Cell Biol 159:23-28. http://dx.doi.org/10.1083/jcb.200206120
    • (2002) J Cell Biol , vol.159 , pp. 23-28
    • Roth, A.F.1    Feng, Y.2    Chen, L.3    Davis, N.G.4
  • 5
    • 33744826797 scopus 로고    scopus 로고
    • Protein palmitoylation by a family of DHHC protein S-acyltransferases
    • Mitchell DA, Vasudevan A, Linder ME, Deschenes RJ. 2006. Protein palmitoylation by a family of DHHC protein S-acyltransferases. J Lipid Res 47:1118-1127. http://dx.doi.org/10.1194/jlr.R600007-JLR200.
    • (2006) J Lipid Res , vol.47 , pp. 1118-1127
    • Mitchell, D.A.1    Vasudevan, A.2    Linder, M.E.3    Deschenes, R.J.4
  • 6
    • 84934293835 scopus 로고    scopus 로고
    • Palmitoylation and depalmitoylation defects
    • Hornemann T. 2015. Palmitoylation and depalmitoylation defects. J Inherit Metab Dis 38:179-186. http://dx.doi.org/10.1007/s10545-014-9753-0
    • (2015) J Inherit Metab Dis , vol.38 , pp. 179-186
    • Hornemann, T.1
  • 8
    • 84858796808 scopus 로고    scopus 로고
    • Ras trafficking, localization and compartmentalized signalling
    • Prior IA, Hancock JF. 2012. Ras trafficking, localization and compartmentalized signalling. Semin Cell Dev Biol 23:145-153. http://dx.doi.org/10.1016/j.semcdb.2011.09.002
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 145-153
    • Prior, I.A.1    Hancock, J.F.2
  • 10
    • 33748931133 scopus 로고    scopus 로고
    • Spatial segregation of Ras signaling: New evidence from fission yeast
    • Chang EC, Philips MR. 2006. Spatial segregation of Ras signaling: new evidence from fission yeast. Cell Cycle 5:1936-1939. http://dx.doi.org/10.4161/cc.5.17.3187
    • (2006) Cell Cycle , vol.5 , pp. 1936-1939
    • Chang, E.C.1    Philips, M.R.2
  • 11
    • 59249084313 scopus 로고    scopus 로고
    • Subcellular localization directs signaling specificity of the Cryptococcus neoformans Ras1 protein
    • Nichols CB, Ferreyra J, Ballou ER, Alspaugh JA. 2009. Subcellular localization directs signaling specificity of the Cryptococcus neoformans Ras1 protein. Eukaryot Cell 8:181-189. http://dx.doi.org/10.1128/EC.00351-08
    • (2009) Eukaryot Cell , vol.8 , pp. 181-189
    • Nichols, C.B.1    Ferreyra, J.2    Ballou, E.R.3    Alspaugh, J.A.4
  • 12
    • 0025978949 scopus 로고
    • Getting started with yeast
    • Sherman F. 1991. Getting started with yeast. Methods Enzymol 194:3-21. http://dx.doi.org/10.1016/0076-6879(91)94004-V
    • (1991) Methods Enzymol , vol.194 , pp. 3-21
    • Sherman, F.1
  • 13
    • 34249882487 scopus 로고    scopus 로고
    • The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants
    • Xue C, Tada Y, Dong X, Heitman J. 2007. The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants. Cell Host Microbe 1:263-273. http://dx.doi.org/10.1016/j.chom.2007.05.005
    • (2007) Cell Host Microbe , vol.1 , pp. 263-273
    • Xue, C.1    Tada, Y.2    Dong, X.3    Heitman, J.4
  • 14
    • 0142216112 scopus 로고    scopus 로고
    • Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. Gattii: Implications for an outbreak on Vancouver Island, Canada
    • Fraser JA, Subaran RL, Nichols CB, Heitman J. 2003. Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. Eukaryot Cell 2:1036-1045. http://dx.doi.org/10.1128/EC.2.5.1036-1045.2003
    • (2003) Eukaryot Cell , vol.2 , pp. 1036-1045
    • Fraser, J.A.1    Subaran, R.L.2    Nichols, C.B.3    Heitman, J.4
  • 15
    • 84863253814 scopus 로고    scopus 로고
    • Targeted gene disruption in Cryptococcus neoformans using double-joint PCR with split dominant selectable markers
    • Kim MS, Kim SY, Jung KW, Bahn YS. 2012. Targeted gene disruption in Cryptococcus neoformans using double-joint PCR with split dominant selectable markers. Methods Mol Biol 845:67-84. http://dx.doi.org/10.1007/978-1-61779-539-8_5
    • (2012) Methods Mol Biol , vol.845 , pp. 67-84
    • Kim, M.S.1    Kim, S.Y.2    Jung, K.W.3    Bahn, Y.S.4
  • 16
    • 33745727752 scopus 로고    scopus 로고
    • Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: Absence of Ku proteins increases homologous recombination, and cotransformation of independent DNA molecules allows rapid complementation of deletion phenotypes
    • Goins CL, Gerik KJ, Lodge JK. 2006. Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: absence of Ku proteins increases homologous recombination, and cotransformation of independent DNA molecules allows rapid complementation of deletion phenotypes. Fungal Genet Biol 43:531-544. http://dx.doi.org/10.1016/j.fgb.2006.02.007
    • (2006) Fungal Genet Biol , vol.43 , pp. 531-544
    • Goins, C.L.1    Gerik, K.J.2    Lodge, J.K.3
  • 18
    • 0034001825 scopus 로고    scopus 로고
    • Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans
    • Davidson RC, Cruz MC, Sia RA, Allen B, Alspaugh JA, Heitman J. 2000. Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans. Fungal Genet Biol 29:38-48. http://dx.doi.org/10.1006/fgbi.1999.1180
    • (2000) Fungal Genet Biol , vol.29 , pp. 38-48
    • Davidson, R.C.1    Cruz, M.C.2    Sia, R.A.3    Allen, B.4    Alspaugh, J.A.5    Heitman, J.6
  • 20
    • 0033944545 scopus 로고    scopus 로고
    • Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae
    • Levine TP, Wiggins CA, Munro S. 2000. Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae. Mol Biol Cell 11:2267-2281. http://dx.doi.org/10.1091/mbc.11.7.2267.
    • (2000) Mol Biol Cell , vol.11 , pp. 2267-2281
    • Levine, T.P.1    Wiggins, C.A.2    Munro, S.3
  • 22
    • 34447115260 scopus 로고    scopus 로고
    • Palmitoylated proteins: Purification and identification
    • Wan J, Roth AF, Bailey AO, Davis NG. 2007. Palmitoylated proteins: purification and identification. Nat Protoc 2:1573-1584. http://dx.doi.org/10.1038/nprot.2007.225.
    • (2007) Nat Protoc , vol.2 , pp. 1573-1584
    • Wan, J.1    Roth, A.F.2    Bailey, A.O.3    Davis, N.G.4
  • 23
    • 0033971038 scopus 로고    scopus 로고
    • Urease as a virulence factor in experimental cryptococcosis
    • Cox GM, Mukherjee J, Cole GT, Casadevall A, Perfect JR. 2000. Urease as a virulence factor in experimental cryptococcosis. Infect Immun 68: 443-448. http://dx.doi.org/10.1128/IAI.68.2.443-448.2000.
    • (2000) Infect Immun , vol.68 , pp. 443-448
    • Cox, G.M.1    Mukherjee, J.2    Cole, G.T.3    Casadevall, A.4    Perfect, J.R.5
  • 27
    • 84867267220 scopus 로고    scopus 로고
    • The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate
    • Mitchell DA, Hamel LD, Ishizuka K, Mitchell G, Schaefer LM, Deschenes RJ. 2012. The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate. J Biol Chem 287:34337-34348. http://dx.doi.org/10.1074/jbc.M112.379297.
    • (2012) J Biol Chem , vol.287 , pp. 34337-34348
    • Mitchell, D.A.1    Hamel, L.D.2    Ishizuka, K.3    Mitchell, G.4    Schaefer, L.M.5    Deschenes, R.J.6
  • 28
    • 24744466287 scopus 로고    scopus 로고
    • DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras
    • Swarthout JT, Lobo S, Farh L, Croke MR, Greentree WK, Deschenes RJ, Linder ME. 2005. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. J Biol Chem 280:31141-31148. http://dx.doi.org/10.1074/jbc.M504113200.
    • (2005) J Biol Chem , vol.280 , pp. 31141-31148
    • Swarthout, J.T.1    Lobo, S.2    Farh, L.3    Croke, M.R.4    Greentree, W.K.5    Deschenes, R.J.6    Linder, M.E.7
  • 29
    • 52949114243 scopus 로고    scopus 로고
    • Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
    • Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, Noble SM. 2008. Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell 135:174-188. http://dx.doi.org/10.1016/j.cell.2008.07.046
    • (2008) Cell , vol.135 , pp. 174-188
    • Liu, O.W.1    Chun, C.D.2    Chow, E.D.3    Chen, C.4    Madhani, H.D.5    Noble, S.M.6
  • 30
    • 33846622349 scopus 로고    scopus 로고
    • A Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans
    • Nichols CB, Perfect ZH, Alspaugh JA. 2007. A Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans. Mol Microbiol 63:1118-1130. http://dx.doi.org/10.1111/j.1365-2958.2006.05566.x.
    • (2007) Mol Microbiol , vol.63 , pp. 1118-1130
    • Nichols, C.B.1    Perfect, Z.H.2    Alspaugh, J.A.3
  • 31
    • 0032883098 scopus 로고    scopus 로고
    • Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae
    • Bartels DJ, Mitchell DA, Dong X, Deschenes RJ. 1999. Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae. Mol Cell Biol 19:6775-6787
    • (1999) Mol Cell Biol , vol.19 , pp. 6775-6787
    • Bartels, D.J.1    Mitchell, D.A.2    Dong, X.3    Deschenes, R.J.4
  • 32
    • 33748955890 scopus 로고    scopus 로고
    • Purification and characterization of recombinant protein acyltransferases
    • Budde C, Schoenfish MJ, Linder ME, Deschenes RJ. 2006. Purification and characterization of recombinant protein acyltransferases. Methods 40:143-150. http://dx.doi.org/10.1016/j.ymeth.2006.07.017
    • (2006) Methods , vol.40 , pp. 143-150
    • Budde, C.1    Schoenfish, M.J.2    Linder, M.E.3    Deschenes, R.J.4
  • 33
    • 84892467472 scopus 로고    scopus 로고
    • Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases
    • Young E, Zheng Z-Y, Wilkins AD, Jeong H-T, Li M, Lichtarge O, Chang EC. 2014. Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases. Mol Cell Biol 34:374-385. http://dx.doi.org/10.1128/MCB.01248-13.
    • (2014) Mol Cell Biol , vol.34 , pp. 374-385
    • Young, E.1    Zheng, Z.-Y.2    Wilkins, A.D.3    Jeong, H.-T.4    Li, M.5    Lichtarge, O.6    Chang, E.C.7
  • 34
    • 0034052527 scopus 로고    scopus 로고
    • RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans
    • Alspaugh JA, Cavallo LM, Perfect JR, Heitman J. 2000. RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans. Mol Microbiol 36:352-365. http://dx.doi.org/10.1046/j.1365-2958.2000.01852.x.
    • (2000) Mol Microbiol , vol.36 , pp. 352-365
    • Alspaugh, J.A.1    Cavallo, L.M.2    Perfect, J.R.3    Heitman, J.4
  • 35
    • 0036148490 scopus 로고    scopus 로고
    • Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans
    • Waugh MS, Nichols CB, DeCesare CM, Cox GM, Heitman J, Alspaugh JA. 2002. Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans. Microbiology 148:191-201.
    • (2002) Microbiology , vol.148 , pp. 191-201
    • Waugh, M.S.1    Nichols, C.B.2    Decesare, C.M.3    Cox, G.M.4    Heitman, J.5    Alspaugh, J.A.6
  • 36
    • 33745623380 scopus 로고    scopus 로고
    • Palmitoylation by the DHHC protein Pfa4 regulates the ER exit of Chs3
    • Lam KK, Davey M, Sun B, Roth AF, Davis NG, Conibear E. 2006. Palmitoylation by the DHHC protein Pfa4 regulates the ER exit of Chs3. J Cell Biol 174:19-25. http://dx.doi.org/10.1083/jcb.200602049.
    • (2006) J Cell Biol , vol.174 , pp. 19-25
    • Lam, K.K.1    Davey, M.2    Sun, B.3    Roth, A.F.4    Davis, N.G.5    Conibear, E.6
  • 37
    • 27744569817 scopus 로고    scopus 로고
    • A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans
    • Banks IR, Specht CA, Donlin MJ, Gerik KJ, Levitz SM, Lodge JK. 2005. A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. Eukaryot Cell 4:1902-1912. http://dx.doi.org/10.1128/EC.4.11.1902-1912.2005.
    • (2005) Eukaryot Cell , vol.4 , pp. 1902-1912
    • Banks, I.R.1    Specht, C.A.2    Donlin, M.J.3    Gerik, K.J.4    Levitz, S.M.5    Lodge, J.K.6
  • 38
    • 34249736906 scopus 로고    scopus 로고
    • Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans
    • Baker LG, Specht CA, Donlin MJ, Lodge JK. 2007. Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans. Eukaryot Cell 6:855-867. http://dx.doi.org/10.1128/EC.00399-06
    • (2007) Eukaryotcell , vol.6 , pp. 855-867
    • Baker, L.G.1    Specht, C.A.2    Donlin, M.J.3    Lodge, J.K.4
  • 39
    • 0030668723 scopus 로고    scopus 로고
    • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP
    • Alspaugh JA, Perfect JR, Heitman J. 1997. Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. Genes Dev 11:3206-3217. http://dx.doi.org/10.1101/gad.11.23.3206
    • (1997) Genes Dev , vol.11 , pp. 3206-3217
    • Alspaugh, J.A.1    Perfect, J.R.2    Heitman, J.3
  • 40
    • 35948947869 scopus 로고    scopus 로고
    • Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans
    • Li L, Shen G, Zhang ZG, Wang YL, Thompson JK, Wang P. 2007. Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans. Mol Biol Cell 18:4201-4209. http://dx.doi.org/10.1091/mbc.E07-02-0136.
    • (2007) Mol Biol Cell , vol.18 , pp. 4201-4209
    • Li, L.1    Shen, G.2    Zhang, Z.G.3    Wang, Y.L.4    Thompson, J.K.5    Wang, P.6
  • 41
    • 0031008864 scopus 로고    scopus 로고
    • Calcineurin is required for virulence of Cryptococcus neoformans
    • Odom A, Muir S, Lim E, Toffaletti DL, Perfect J, Heitman J. 1997. Calcineurin is required for virulence of Cryptococcus neoformans. EMBO J 16:2576-2589. http://dx.doi.org/10.1093/emboj/16.10.2576.
    • (1997) EMBO J , vol.16 , pp. 2576-2589
    • Odom, A.1    Muir, S.2    Lim, E.3    Toffaletti, D.L.4    Perfect, J.5    Heitman, J.6
  • 42
    • 75149112224 scopus 로고    scopus 로고
    • Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions
    • Ballou ER, Nichols CB, Miglia KJ, Kozubowski L, Alspaugh JA. 2010. Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions. Mol Microbiol 75:763-780. http://dx.doi.org/10.1111/j.1365-2958.2009.07019.x.
    • (2010) Mol Microbiol , vol.75 , pp. 763-780
    • Ballou, E.R.1    Nichols, C.B.2    Miglia, K.J.3    Kozubowski, L.4    Alspaugh, J.A.5
  • 43
    • 77951755936 scopus 로고    scopus 로고
    • The Fungal Genetics Stock Center: A repository for 50 years of fungal genetics research
    • McCluskey K, Wiest A, Plamann M. 2010. The Fungal Genetics Stock Center: a repository for 50 years of fungal genetics research. J Biosci 35: 119-126. http://dx.doi.org/10.1007/s12038-010-0014-6.
    • (2010) J Biosci , vol.35 , pp. 119-126
    • McCluskey, K.1    Wiest, A.2    Plamann, M.3
  • 44
    • 0018927330 scopus 로고
    • Chronic cryptococcal meningitis: A new experimental model in rabbits
    • Perfect JR, Lang SD, Durack DT. 1980. Chronic cryptococcal meningitis: a new experimental model in rabbits. Am J Pathol 101:177-194
    • (1980) Am J Pathol , vol.101 , pp. 177-194
    • Perfect, J.R.1    Lang, S.D.2    Durack, D.T.3
  • 45
    • 0041971075 scopus 로고    scopus 로고
    • Sexual cycle of Cryptococcus neoformans var. Grubii and virulence of congenic a andisolates
    • Nielsen K, Cox GM, Wang P, Toffaletti DL, Perfect JR, Heitman J. 2003. Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and isolates. Infect Immun 71:4831-4841. http://dx.doi.org/10.1128/IAI.71.9.4831-4841.2003
    • (2003) Infect Immun , vol.71 , pp. 4831-4841
    • Nielsen, K.1    Cox, G.M.2    Wang, P.3    Toffaletti, D.L.4    Perfect, J.R.5    Heitman, J.6
  • 46
    • 84886390606 scopus 로고    scopus 로고
    • Restricted substrate specificity for the geranylgeranyltransferase-I enzyme in Cryptococcus neoformans: Implications for virulence
    • Selvig K, Ballou ER, Nichols CB, Alspaugh JA. 2013. Restricted substrate specificity for the geranylgeranyltransferase-I enzyme in Cryptococcus neoformans: implications for virulence. Eukaryot Cell 12:1462-1471. http: //dx.doi.org/10.1128/EC.00193-13
    • (2013) Eukaryot Cell , vol.12 , pp. 1462-1471
    • Selvig, K.1    Ballou, E.R.2    Nichols, C.B.3    Alspaugh, J.A.4


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