Wogonin increases β-amyloid clearance and inhibits tau phosphorylation via inhibition of mammalian target of rapamycin: potential drug to treat Alzheimer’s disease

Neurological Sciences

Volumn 36, Issue 7, 2015, Pages 1181-1188

  Zhu, Yuyou ^a   Wang, Juan ^a  

^a ANHUI PROVINCIAL HOSPITAL   (China)

Author keywords

Alzheimer s disease (AD); Autophagy; Mammalian target of rapamycin (mTOR); Tau; Wogonin; Amyloid (A )

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GLYCOGEN SYNTHASE KINASE 3; MAMMALIAN TARGET OF RAPAMYCIN; TAU PROTEIN; WOGONIN; AMYLOID BETA PROTEIN[1-40]; FLAVANONE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3 BETA; GREEN FLUORESCENT PROTEIN; MTOR PROTEIN, HUMAN; PEPTIDE FRAGMENT; TARGET OF RAPAMYCIN KINASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; AUTOPHAGY; CLEARANCE; CONCENTRATION (PARAMETERS); EMBRYO; FEMALE; HUMAN; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STABLE EXPRESSION; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CONFOCAL MICROSCOPY; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; NEUROBLASTOMA; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; AUTOPHAGY; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; FLAVANONES; GLYCOGEN SYNTHASE KINASE 3; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSCOPY, CONFOCAL; NEUROBLASTOMA; PEPTIDE FRAGMENTS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TAU PROTEINS; TOR SERINE-THREONINE KINASES; TRANSFECTION;

EID: 84933679571     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-015-2070-z     Document Type: Article

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