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Volumn 23, Issue 2, 2009, Pages 146-153

Scutellaria flavonoid supplementation reverses ageing-related cognitive impairment and neuronal changes in aged rats

Author keywords

Aged rats; Cognitive impairment; Flavonoid; LDH; MDA; Morris water maze; Na + K + ATPase; Neuronal damage; Scutellaria baicalensis Georgi; SOD

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); FLAVANOID; LACTATE DEHYDROGENASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

EID: 59749096774     PISSN: 02699052     EISSN: 1362301X     Source Type: Journal    
DOI: 10.1080/02699050802649670     Document Type: Article
Times cited : (24)

References (28)
  • 3
    • 1842665096 scopus 로고    scopus 로고
    • Improving effects of SSF on memory deficits and pathological changes of neural and immunological systems in senescent mice
    • Shang, YZ, Gong, MY, Zhou, XX, Li, ST and Wang BY (2001) Improving effects of SSF on memory deficits and pathological changes of neural and immunological systems in senescent mice. Acta Pharmacologica Sinica, 22, pp. 1078-1083.
    • (2001) Acta Pharmacologica Sinica , vol.22 , pp. 1078-1083
    • Shang, Y.Z.1    Gong, M.Y.2    Zhou, X.X.3    Li, S.T.4    Wang, B.Y.5
  • 4
    • 0035876056 scopus 로고    scopus 로고
    • Huperzine A attenuates cognitive dysfunction and neuronal degeneration caused by beta-amyloid protein-(1-40) in rat
    • Wang, R., Zhang, HY and Tang, XC (2001) Huperzine A attenuates cognitive dysfunction and neuronal degeneration caused by beta-amyloid protein-(1-40) in rat. European Journal of Pharmacology, 421, pp. 149-156.
    • (2001) European Journal of Pharmacology , vol.421 , pp. 149-156
    • Wang, R.1    Zhang, H.Y.2    Tang, X.C.3
  • 6
    • 0032421523 scopus 로고    scopus 로고
    • Senescence-accelerated mouse (SAM) as an animal model of senile dementia: Pharmacological, neurochemical and molecular biological approach
    • Okuma, Y. and Nomura, Y. (1998) Senescence-accelerated mouse (SAM) as an animal model of senile dementia: Pharmacological, neurochemical and molecular biological approach. Japanese Journal of Pharmacology, 78, pp. 399-404.
    • (1998) Japanese Journal of Pharmacology , vol.78 , pp. 399-404
    • Okuma, Y.1    Nomura, Y.2
  • 7
    • 0033965420 scopus 로고    scopus 로고
    • Huperzine A ameliorates the impaired memory of aged rat in the Morris water maze performance
    • Ye, JW, Shang, YZ, Wang, ZM and Tang, XC (2000) Huperzine A ameliorates the impaired memory of aged rat in the Morris water maze performance. Acta Pharmacologica Sinica, 21, pp. 65-69.
    • (2000) Acta Pharmacologica Sinica , vol.21 , pp. 65-69
    • Ye, J.W.1    Shang, Y.Z.2    Wang, Z.M.3    Tang, X.C.4
  • 8
    • 0038682438 scopus 로고    scopus 로고
    • Progress of the animal models on Alzheimer's disease
    • Cong, WH and Liu, JX (2003) Progress of the animal models on Alzheimer's disease. Chinese Pharmacology Bulletin, 19, pp. 497-501.
    • (2003) Chinese Pharmacology Bulletin , vol.19 , pp. 497-501
    • Cong, W.H.1    Liu, J.X.2
  • 9
    • 4944235410 scopus 로고    scopus 로고
    • Protective effects of total flavonoids from stems and leaves of Scutellaria baicalensis Georgi on cerebral hypoxia in mice
    • Shang, YZ and Cao, K. (2004) Protective effects of total flavonoids from stems and leaves of Scutellaria baicalensis Georgi on cerebral hypoxia in mice. Chinese Journal of Clinical Rehabilitation, 8, pp. 3908-3909.
    • (2004) Chinese Journal of Clinical Rehabilitation , vol.8 , pp. 3908-3909
    • Shang, Y.Z.1    Cao, K.2
  • 10
    • 26444600788 scopus 로고    scopus 로고
    • Scutellaria flavonoid reduced memory dysfunction and neuronal injury caused by permanent global ischemia in rats
    • Shang, YZ, Cheng, JJ, Qi, JM and Miao, H. (2005) Scutellaria flavonoid reduced memory dysfunction and neuronal injury caused by permanent global ischemia in rats. Pharmacology and Biochemistry of Behavior, 82, pp. 67-73.
    • (2005) Pharmacology and Biochemistry of Behavior , vol.82 , pp. 67-73
    • Shang, Y.Z.1    Cheng, J.J.2    Qi, J.M.3    Miao, H.4
  • 11
    • 31644437578 scopus 로고    scopus 로고
    • Prevention of oxidative injury by flavonoids from stems and leaves of Scutellaria baicalensis Georgi in PC12 cells
    • Shang, YZ, Qin, BW, Cheng, JJ and Miao, H. (2006) Prevention of oxidative injury by flavonoids from stems and leaves of Scutellaria baicalensis Georgi in PC12 cells. Phytotherapy Research, 20, pp. 53-57.
    • (2006) Phytotherapy Research , vol.20 , pp. 53-57
    • Shang, Y.Z.1    Qin, B.W.2    Cheng, J.J.3    Miao, H.4
  • 13
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rats
    • Morris, R. (1984) Developments of a water-maze procedure for studying spatial learning in the rats. Journal of Neuroscience Methods, 11, pp. 47-60.
    • (1984) Journal of Neuroscience Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 14
    • 0041654505 scopus 로고    scopus 로고
    • Effects of α-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat
    • Feng, RF, Li, WB, Liu, HQ, Li, QJ, Chen, QL, Zhou, AM, Zhao, HG and Ai, J. (2003) Effects of α-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat. Acta Physiologica Sinica, 55, pp. 303-310.
    • (2003) Acta Physiologica Sinica , vol.55 , pp. 303-310
    • Feng, R.F.1    Li, W.B.2    Liu, H.Q.3    Li, Q.J.4    Chen, Q.L.5    Zhou, A.M.6    Zhao, H.G.7    Ai, J.8
  • 15
    • 20544454810 scopus 로고    scopus 로고
    • Effect of yishenjiangzhuo decoction on the ultrastructure of hippocampus in cerebralischemia-reperfusion rats
    • Yuan, GH, Gao, WJ, Ma, WJ, Han, L., Liu, S. and Zhao, SM (2003) Effect of yishenjiangzhuo decoction on the ultrastructure of hippocampus in cerebralischemia-reperfusion rats. Journal of Chengde Medical College, 20, pp. 4-5.
    • (2003) Journal of Chengde Medical College , vol.20 , pp. 4-5
    • Yuan, G.H.1    Gao, W.J.2    Ma, W.J.3    Han, L.4    Liu, S.5    Zhao, S.M.6
  • 16
    • 0035145760 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice
    • Duan, WZ, Guo, ZH and Mattson, MP (2001) Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice. Journal of Neurochemistry, 76, pp. 619-626.
    • (2001) Journal of Neurochemistry , vol.76 , pp. 619-626
    • Duan, W.Z.1    Guo, Z.H.2    Mattson, M.P.3
  • 19
    • 0032888723 scopus 로고    scopus 로고
    • Improving effects of huperzine A on abnormal lipid peroxidation and superoxide dismutase in aged rats
    • Shang, YZ, Ye, JW and Tang, XC (1999) Improving effects of huperzine A on abnormal lipid peroxidation and superoxide dismutase in aged rats. Acta Pharmacologica Sinica, 20, pp. 824-828.
    • (1999) Acta Pharmacologica Sinica , vol.20 , pp. 824-828
    • Shang, Y.Z.1    Ye, J.W.2    Tang, X.C.3
  • 20
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72, pp. 248-254.
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 22
    • 59749091984 scopus 로고    scopus 로고
    • The research progress and application of aging mechanism
    • Fu, YR and Wang, Y. (2003) The research progress and application of aging mechanism. Foreign Medical Sciences in Geriatrics, 24, pp. 147-150.
    • (2003) Foreign Medical Sciences in Geriatrics , vol.24 , pp. 147-150
    • Fu, Y.R.1    Wang, Y.2
  • 23
    • 0028951951 scopus 로고
    • Cholinergic binding sites in rat brain: Analysis by age and cognitive status
    • Smith, TD, Gallagher, M. and Leslie, FM (1995) Cholinergic binding sites in rat brain: Analysis by age and cognitive status. Neurobiology of Aging, 16, pp. 161-173.
    • (1995) Neurobiology of Aging , vol.16 , pp. 161-173
    • Smith, T.D.1    Gallagher, M.2    Leslie, F.M.3
  • 24
    • 4444359549 scopus 로고    scopus 로고
    • Delayed neuronal death and damage of GDNF family receptors in CA1 following focal cerebral ischemia
    • Wang, W., Redecker, C., Bidmon, HJ and Witte, OW (2004) Delayed neuronal death and damage of GDNF family receptors in CA1 following focal cerebral ischemia. Brain Research, 1023, pp. 92-101.
    • (2004) Brain Research , vol.1023 , pp. 92-101
    • Wang, W.1    Redecker, C.2    Bidmon, H.J.3    Witte, O.W.4
  • 25
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • Markesbery, WR (1997) Oxidative stress hypothesis in Alzheimer's disease. Free Radical Biology and Medicine, 23, pp. 134-147.
    • (1997) Free Radical Biology and Medicine , vol.23 , pp. 134-147
    • Markesbery, W.R.1
  • 27
    • 0032412522 scopus 로고    scopus 로고
    • Dietary antioxidant supplementation reverses age-related neuronal changes
    • O'Donnell, E. and Lynch, MA (1998) Dietary antioxidant supplementation reverses age-related neuronal changes. Neurobiology of Aging, 9, pp. 461-467.
    • (1998) Neurobiology of Aging , vol.9 , pp. 461-467
    • O'Donnell, E.1    Lynch, M.A.2
  • 28
    • 0027792335 scopus 로고
    • Transgenic mice overexpressing copper-zinc superoxide dismutase: A model for the study of radical mechanisms and aging
    • Ceballos-Picot, I. (1993) Transgenic mice overexpressing copper-zinc superoxide dismutase: A model for the study of radical mechanisms and aging. Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales, 187, pp. 308-323.
    • (1993) Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales , vol.187 , pp. 308-323
    • Ceballos-Picot, I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.