The Neisseria gonorrhoeae Obg protein is an essential ribosome-associated GTPase and a potential drug target

BMC Microbiology

Volumn 15, Issue 1, 2015, Pages

  Zielke, Ryszard A ^a   Wierzbicki, Igor H ^a   Baarda, Benjamin I ^a   Sikora, Aleksandra E ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Drug resistance; Drug target; GTPase; Mant guanine nucleotides; Neisseria gonorrhoeae; Obg proteins

Indexed keywords

GUANINE NUCLEOTIDE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; OBG PROTEIN; RIBOSOME PROTEIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIUM ANTIBODY; GUANINE NUCLEOTIDE BINDING PROTEIN; OBG GTP-BINDING PROTEIN, BACTERIA; PROTEIN BINDING; VIRULENCE FACTOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM ISOLATE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CROSS REACTION; DNA PROTEIN COMPLEX; GENE LOCUS; GENETIC LINKAGE; IN VITRO STUDY; NEISSERIA GONORRHOEAE; NONHUMAN; OBG GENE; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; PROTEIN TARGETING; RPLU GENE; RPMA GENE; SEQUENCE ANALYSIS; BLOOD; ESSENTIAL GENE; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; LARGE RIBOSOMAL SUBUNIT; MALE; METABOLISM; MICROBIAL VIABILITY; PATHOGENICITY; PHYSIOLOGY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA GONORRHOEAE;

ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; FEMALE; GENES, ESSENTIAL; GTP-BINDING PROTEINS; HUMANS; MALE; MICROBIAL VIABILITY; NEISSERIA GONORRHOEAE; PROTEIN BINDING; RIBOSOME SUBUNITS, LARGE, BACTERIAL; VIRULENCE FACTORS;

EID: 84933532217     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/s12866-015-0453-1     Document Type: Article

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