MRI-guided neutron capture therapy by use of a dual gadolinium/boron agent targeted at tumour cells through upregulated low-density lipoprotein transporters

Chemistry - A European Journal

Volumn 17, Issue 30, 2011, Pages 8479-8486

  Geninatti Crich, Simonetta ^a   Alberti, Diego ^a   Szabo, Ibolya ^a   Deagostino, Annamaria ^a   Toppino, Antonio ^a   Barge, Alessandro ^a   Ballarini, Francesca ^b,c   Bortolussi, Silva ^b,c   Bruschi, Piero ^b   Protti, Nicoletta ^b,c   Stella, Sabrina ^b,c   Altieri, Saverio ^b,c   Venturello, Paolo ^a   Aime, Silvio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c INFN SEZIONE DI PAVIA   (Italy)

Author keywords

boron; gadolinium; lipoproteins; magnetic resonance imaging; nanotechnology; neutron capture therapy

Indexed keywords

ALIPHATIC CHAINS; B ATOMS; CARBORANES; CONTROL GROUPS; GLIOBLASTOMAS; HUMAN HEPATOMAS; IN-VIVO; INDUCTIVELY-COUPLED; LIPOPROTEINS; LOW DENSITY LIPOPROTEINS; MAGNETIC RESONANCE IMAGES; NEUTRON CAPTURE THERAPY; TUMOUR CELLS; TUMOUR GROWTH; UP-REGULATION;

ANIMAL CELL CULTURE; BEARINGS (STRUCTURAL); BORON; BORON COMPOUNDS; CELLS; GADOLINIUM; INDUCTIVELY COUPLED PLASMA; MAGNETIC RESONANCE IMAGING; MAMMALS; NEUTRON IRRADIATION; NEUTRONS; PROBES; RESONANCE;

TUMORS;

BORON; CARRIER PROTEIN; GADOLINIUM;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; EXPERIMENTAL MELANOMA; HUMAN; METABOLISM; METHODOLOGY; MOUSE; NEUTRON CAPTURE THERAPY; NUCLEAR MAGNETIC RESONANCE IMAGING; TUMOR CELL LINE; UPREGULATION;

ANIMALS; BORON; CARRIER PROTEINS; CELL LINE, TUMOR; GADOLINIUM; HUMANS; MAGNETIC RESONANCE IMAGING; MELANOMA, EXPERIMENTAL; MICE; MOLECULAR STRUCTURE; NEUTRON CAPTURE THERAPY; UP-REGULATION;

EID: 79960316458     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201003741     Document Type: Article

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