Characterization of the release profile of doxycycline by PLGA microspheres adjunct to non-surgical periodontal therapy

Journal of Biomaterials Science, Polymer Edition

Volumn 26, Issue 10, 2015, Pages 573-584

  Moura, Lucas Alves ^a,b   Ribeiro, Fernanda Vieira ^c   Aiello, Talita Bianchi ^b   Duek, Eliana Ap De Rezende ^b   Sallum, Enilson Antonio ^a   Nociti, Francisco Humberto ^a   Casati, Márcio Zaffalon ^a   Sallum, Antonio Wilson ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b PONTIFÍCIA UNIVERSIDADE CATÓLICA DE SÃO PAULO   (Brazil)

^c PAULISTA UNIVERSITY   (Brazil)

Author keywords

delivery system; doxycycline; FTIR; HPLC; microspheres; non surgical periodontal therapy; PLGA

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROSPHERES; ORGANIC POLYMERS; SURGERY; TARGETED DRUG DELIVERY;

DELIVERY SYSTEMS; DOXYCYCLINE; FTIR; HPLC; NON-SURGICAL PERIODONTAL THERAPY; PLGA;

CONTROLLED DRUG DELIVERY;

DOXYCYCLINE HYCLATE; DRUG CARRIER; POLY(LEVO LACTIDE CO GLYCOCIDE) MICROSPHERE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; DOXYCYCLINE; LACTIC ACID; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ARTICLE; CHRONIC PERIODONTITIS; CLINICAL ARTICLE; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFRARED SPECTROSCOPY; MINIMUM INHIBITORY CONCENTRATION; PERIODONTAL POCKET; PERIODONTICS; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; GINGIVITIS;

ANTI-BACTERIAL AGENTS; DOXYCYCLINE; DRUG CARRIERS; DRUG LIBERATION; GINGIVAL CREVICULAR FLUID; HUMANS; LACTIC ACID; MICROSPHERES; PERIODONTAL POCKET; POLYGLYCOLIC ACID;

EID: 84933181273     PISSN: 09205063     EISSN: 15685624     Source Type: Journal    
DOI: 10.1080/09205063.2015.1045249     Document Type: Article

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