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Volumn 79, Issue 3, 2008, Pages 469-476

The effect of adjunctive subantimicrobial dose doxycycline therapy on GCF EMMPRIN levels in chronic periodontitis

Author keywords

Doxycycline; EMMPRIN; Gingival crevicular fluid; Matrix metalloproteinases; Root planing

Indexed keywords

ANTIINFECTIVE AGENT; CD147 ANTIGEN; DOXYCYCLINE;

EID: 41449089786     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2008.070165     Document Type: Article
Times cited : (33)

References (53)
  • 1
    • 33644853421 scopus 로고    scopus 로고
    • Molecular and cell biology of healthy and diseased periodontal tissues
    • Bartold PM, Narayanan AS. Molecular and cell biology of healthy and diseased periodontal tissues. Periodontol 2000 2006;40:29-49.
    • (2006) Periodontol 2000 , vol.40 , pp. 29-49
    • Bartold, P.M.1    Narayanan, A.S.2
  • 2
    • 9444232274 scopus 로고    scopus 로고
    • Matrix metalloproteinases (MMPs) in oral diseases
    • Sorsa T, Tjaderhane L, Salo T. Matrix metalloproteinases (MMPs) in oral diseases. Oral Dis 2004;10:311-318.
    • (2004) Oral Dis , vol.10 , pp. 311-318
    • Sorsa, T.1    Tjaderhane, L.2    Salo, T.3
  • 3
    • 0035479845 scopus 로고    scopus 로고
    • Matrix metalloproteinases: They're not just for matrix anymore!
    • McCawley LJ, Matrisian LM. Matrix metalloproteinases: They're not just for matrix anymore! Curr Opin Cell Biol 2001;13:534-540.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 534-540
    • McCawley, L.J.1    Matrisian, L.M.2
  • 4
    • 33748638853 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation
    • Sorsa T, Tjaderhane L, Konttinen YT, et al. Matrix metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Ann Med 2006;38:306-321.
    • (2006) Ann Med , vol.38 , pp. 306-321
    • Sorsa, T.1    Tjaderhane, L.2    Konttinen, Y.T.3
  • 5
    • 33847195428 scopus 로고    scopus 로고
    • Matrix metal-loproteinases and the regulation of tissue remodelling
    • Page-McCaw A, Ewald AJ, Werb Z. Matrix metal-loproteinases and the regulation of tissue remodelling. Nat Rev Mol Cell Biol 2007;8:221-233.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 221-233
    • Page-McCaw, A.1    Ewald, A.J.2    Werb, Z.3
  • 6
    • 0028795147 scopus 로고
    • The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
    • Biswas C, Zhang Y, DeCastro R, et al. The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res 1995;55:434-439.
    • (1995) Cancer Res , vol.55 , pp. 434-439
    • Biswas, C.1    Zhang, Y.2    DeCastro, R.3
  • 7
    • 0031036521 scopus 로고    scopus 로고
    • Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells
    • Guo H, Zucker S, Gordon MK, Toole BP, Biswas C. Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem 1997;272:24-27.
    • (1997) J Biol Chem , vol.272 , pp. 24-27
    • Guo, H.1    Zucker, S.2    Gordon, M.K.3    Toole, B.P.4    Biswas, C.5
  • 8
    • 0034976637 scopus 로고    scopus 로고
    • Tumorigenic potential of extracellular matrix metalloproteinase inducer
    • Zucker S, Hymowitz M, Rollo EE, et al. Tumorigenic potential of extracellular matrix metalloproteinase inducer. Am J Pathol 2001;158:1921-1928.
    • (2001) Am J Pathol , vol.158 , pp. 1921-1928
    • Zucker, S.1    Hymowitz, M.2    Rollo, E.E.3
  • 9
    • 0035266353 scopus 로고    scopus 로고
    • Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metal-loproteinase inducer interactions
    • Sun J, Hemler ME. Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metal-loproteinase inducer interactions. Cancer Res 2001; 61:2276-2281.
    • (2001) Cancer Res , vol.61 , pp. 2276-2281
    • Sun, J.1    Hemler, M.E.2
  • 10
    • 0027328322 scopus 로고
    • Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase
    • Kataoka H, DeCastro R, Zucker S, Biswas C. Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase. Cancer Res 1993;53:3154-3158.
    • (1993) Cancer Res , vol.53 , pp. 3154-3158
    • Kataoka, H.1    DeCastro, R.2    Zucker, S.3    Biswas, C.4
  • 11
    • 25844504656 scopus 로고    scopus 로고
    • Advances in the pathogenesis of periodontitis. Group B consensus report of the fifth European Workshop in Periodontology
    • Kinane DF, Attström R. Advances in the pathogenesis of periodontitis. Group B consensus report of the fifth European Workshop in Periodontology. J Clin Periodontol 2005;32:130-131.
    • (2005) J Clin Periodontol , vol.32 , pp. 130-131
    • Kinane, D.F.1    Attström, R.2
  • 12
    • 0033017705 scopus 로고    scopus 로고
    • Host modulation as a therapeutic strategy in the treatment of periodontal disease
    • Kornman KS. Host modulation as a therapeutic strategy in the treatment of periodontal disease. Clin Infect Dis 1999;28:520-526.
    • (1999) Clin Infect Dis , vol.28 , pp. 520-526
    • Kornman, K.S.1
  • 13
    • 0032200444 scopus 로고    scopus 로고
    • Tetracyclines inhibit connective tissue break-down by multiple non-antimicrobial mechanisms
    • Golub LM, Lee HM, Ryan ME, Giannobile WV, Payne J, Sorsa T. Tetracyclines inhibit connective tissue break-down by multiple non-antimicrobial mechanisms. Adv Dent Res 1998;12:12-26.
    • (1998) Adv Dent Res , vol.12 , pp. 12-26
    • Golub, L.M.1    Lee, H.M.2    Ryan, M.E.3    Giannobile, W.V.4    Payne, J.5    Sorsa, T.6
  • 14
    • 0025875557 scopus 로고
    • Tetracy-clines inhibit connective tissue breakdown: New therapeutic implications for an old family of drugs
    • Golub LM, Ramamurthy NS, McNamara TF. Tetracy-clines inhibit connective tissue breakdown: New therapeutic implications for an old family of drugs. Crit Rev Oral Biol Med 1991;2:297-322.
    • (1991) Crit Rev Oral Biol Med , vol.2 , pp. 297-322
    • Golub, L.M.1    Ramamurthy, N.S.2    McNamara, T.F.3
  • 16
    • 0025686083 scopus 로고
    • Low-dose doxycycline therapy: Effect on gingival and crevicular fluid collagenase activity in humans
    • Golub LM, Ciancio S, Ramamurthy NS, Leung M, McNamara TF. Low-dose doxycycline therapy: Effect on gingival and crevicular fluid collagenase activity in humans. J Periodontal Res 1990;25:321-330.
    • (1990) J Periodontal Res , vol.25 , pp. 321-330
    • Golub, L.M.1    Ciancio, S.2    Ramamurthy, N.S.3    Leung, M.4    McNamara, T.F.5
  • 17
    • 0028658357 scopus 로고
    • A non-antimicrobial tetracycline inhibits gingival matrix metalloproteinases and bone loss in Porphyromonas gingivalis-induced periodontitis in rats
    • Golub LM, Evans RT, McNamara TF, Lee HM, Ramamurthy NS. A non-antimicrobial tetracycline inhibits gingival matrix metalloproteinases and bone loss in Porphyromonas gingivalis-induced periodontitis in rats. Ann N Y Acad Sci 1994;732:96-111.
    • (1994) Ann N Y Acad Sci , vol.732 , pp. 96-111
    • Golub, L.M.1    Evans, R.T.2    McNamara, T.F.3    Lee, H.M.4    Ramamurthy, N.S.5
  • 18
    • 0030862107 scopus 로고    scopus 로고
    • A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis
    • Golub LM, Lee HM, Greenwald RA, et al. A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis. Inflamm Res 1997;46:310-319.
    • (1997) Inflamm Res , vol.46 , pp. 310-319
    • Golub, L.M.1    Lee, H.M.2    Greenwald, R.A.3
  • 19
    • 0023245356 scopus 로고
    • A non-antibacterial chemically-modified tetracycline inhibits mammalian collagenase activity
    • Golub LM, McNamara TF, D'Angelo G, Greenwald RA, Ramamurthy NS. A non-antibacterial chemically-modified tetracycline inhibits mammalian collagenase activity. J Dent Res 1987;66:1310-1314.
    • (1987) J Dent Res , vol.66 , pp. 1310-1314
    • Golub, L.M.1    McNamara, T.F.2    D'Angelo, G.3    Greenwald, R.A.4    Ramamurthy, N.S.5
  • 20
    • 0035256275 scopus 로고    scopus 로고
    • Adjunctive treatment with subantimicrobial doses of doxycycline: Effects on gingival fluid collagenase activity and attachment loss in adult periodontitis
    • Golub LM, McNamara TF, Ryan ME, et al. Adjunctive treatment with subantimicrobial doses of doxycycline: Effects on gingival fluid collagenase activity and attachment loss in adult periodontitis. J Clin Periodontol 2001 ; 28:146-156.
    • (2001) J Clin Periodontol , vol.28 , pp. 146-156
    • Golub, L.M.1    McNamara, T.F.2    Ryan, M.E.3
  • 21
    • 0029245540 scopus 로고
    • Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva
    • Golub LM, Sorsa T, Lee H-M, et ai. Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva. J Clin Periodontol 1995;22:100-109.
    • (1995) J Clin Periodontol , vol.22 , pp. 100-109
    • Golub, L.M.1    Sorsa, T.2    Lee, H.-M.3    et ai4
  • 22
    • 1542360543 scopus 로고    scopus 로고
    • The effect of adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis
    • Emingil G, Atilla G, Sorsa T, Luoto H, Kirilmaz L, Baylas H. The effect of adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis. J Periodontol 2004;75:106-115.
    • (2004) J Periodontol , vol.75 , pp. 106-115
    • Emingil, G.1    Atilla, G.2    Sorsa, T.3    Luoto, H.4    Kirilmaz, L.5    Baylas, H.6
  • 23
    • 0033862278 scopus 로고    scopus 로고
    • Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis
    • Caton JG, Ciancio SG, Blieden TM, et al. Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis. J Periodontol 2000;71:521-532.
    • (2000) J Periodontol , vol.71 , pp. 521-532
    • Caton, J.G.1    Ciancio, S.G.2    Blieden, T.M.3
  • 24
    • 1542653032 scopus 로고    scopus 로고
    • Effects of sub-antimicrobial dose doxycycline therapy on crevicular fluid MMP-8, and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitis
    • Choi D, Moon I-S, Choi B-K, et al. Effects of sub-antimicrobial dose doxycycline therapy on crevicular fluid MMP-8, and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitis. J Periodontal Res 2004;39:20-26.
    • (2004) J Periodontal Res , vol.39 , pp. 20-26
    • Choi, D.1    Moon, I.-S.2    Choi, B.-K.3
  • 25
    • 10944256349 scopus 로고    scopus 로고
    • Effect of subantimicrobial dose doxycycline as an effective adjunct to scaling and root planing
    • Lee JY, Lee YM, Shin SY, et al. Effect of subantimicrobial dose doxycycline as an effective adjunct to scaling and root planing. J Periodontol 2004;75:1500-1508.
    • (2004) J Periodontol , vol.75 , pp. 1500-1508
    • Lee, J.Y.1    Lee, Y.M.2    Shin, S.Y.3
  • 26
    • 33846392230 scopus 로고    scopus 로고
    • Adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid tissue plasminogen activator levels in chronic periodontitis
    • Emingil G, Gürkan A, Atilla G, Berdeli A, Çinarcik S. Adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid tissue plasminogen activator levels in chronic periodontitis. Inflamm Res 2006;55:550-558.
    • (2006) Inflamm Res , vol.55 , pp. 550-558
    • Emingil, G.1    Gürkan, A.2    Atilla, G.3    Berdeli, A.4    Çinarcik, S.5
  • 27
    • 15244344671 scopus 로고    scopus 로고
    • EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair
    • Gabison EE, Xuan TH, Mauviel A, Menashi S. EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie 2005;87:361-368.
    • (2005) Biochimie , vol.87 , pp. 361-368
    • Gabison, E.E.1    Xuan, T.H.2    Mauviel, A.3    Menashi, S.4
  • 28
    • 0029888651 scopus 로고    scopus 로고
    • Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer
    • DeCastro R, Zhang Y, Guo H, et al. Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer. J Invest Dermatol 1996;106: 1260-1265.
    • (1996) J Invest Dermatol , vol.106 , pp. 1260-1265
    • DeCastro, R.1    Zhang, Y.2    Guo, H.3
  • 29
    • 33751174728 scopus 로고    scopus 로고
    • Immunolocalization of EMMPRIN (CD147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids
    • Maatta M, Tervahartiala T, Kaarniranta K, et al. Immunolocalization of EMMPRIN (CD147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids. Curr Eye Res 2006;31:917-924.
    • (2006) Curr Eye Res , vol.31 , pp. 917-924
    • Maatta, M.1    Tervahartiala, T.2    Kaarniranta, K.3
  • 30
    • 0034080198 scopus 로고    scopus 로고
    • Increased expression of extracellular matrix metalloproteinase inducer in rheumatoid synovium
    • Konttinen YT, Li TF, Mandelin J, et al. Increased expression of extracellular matrix metalloproteinase inducer in rheumatoid synovium. Arthritis Rheum 2000; 43:275-280.
    • (2000) Arthritis Rheum , vol.43 , pp. 275-280
    • Konttinen, Y.T.1    Li, T.F.2    Mandelin, J.3
  • 31
    • 34548752764 scopus 로고    scopus 로고
    • A potential role of EMMPRIN by regulating ECM degradation in periodontitis
    • Cao Z, Xiang J, Li C. A potential role of EMMPRIN by regulating ECM degradation in periodontitis. Med Hypotheses 2007;69:1102-1104.
    • (2007) Med Hypotheses , vol.69 , pp. 1102-1104
    • Cao, Z.1    Xiang, J.2    Li, C.3
  • 32
    • 33845762432 scopus 로고    scopus 로고
    • Gingival crevicular fluid matrix metalloproteinase-7, extracellular matrix metalloproteinase inducer (EMMPRIN) and tissue inhibitor of MMP (TIMP)-1 levels in periodontal disease
    • Emingil G, Tervahartiala T, Mãntylã P, Määttä M, Sorsa T, Atilla G. Gingival crevicular fluid matrix metalloproteinase-7, extracellular matrix metalloproteinase inducer (EMMPRIN) and tissue inhibitor of MMP (TIMP)-1 levels in periodontal disease. J Periodontal 2006;77:2040-2050.
    • (2006) J Periodontal , vol.77 , pp. 2040-2050
    • Emingil, G.1    Tervahartiala, T.2    Mãntylã, P.3    Määttä, M.4    Sorsa, T.5    Atilla, G.6
  • 33
    • 0033288546 scopus 로고    scopus 로고
    • Development of a classification system for periodontal diseases and conditions
    • Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontal 1999;4:1-6.
    • (1999) Ann Periodontal , vol.4 , pp. 1-6
    • Armitage, G.C.1
  • 34
    • 75549115165 scopus 로고
    • Periodontal disease in pregnancy. Prevalence and severity
    • Löe H, Silness J. Periodontal disease in pregnancy. Prevalence and severity. Acta Odontol Scand 1963;21: 533-551.
    • (1963) Acta Odontol Scand , vol.21 , pp. 533-551
    • Löe, H.1    Silness, J.2
  • 35
    • 0014706824 scopus 로고
    • Reduced plaque formation by the chloromethyl analogue of vitamin C
    • Turesky S, Gilmore ND, Glickman I. Reduced plaque formation by the chloromethyl analogue of vitamin C. J Periodontol 1970;41:41 -43.
    • (1970) J Periodontol , vol.41 , pp. 41-43
    • Turesky, S.1    Gilmore, N.D.2    Glickman, I.3
  • 36
    • 0021984785 scopus 로고
    • Evaluation and modification of spectrophotometric procedures for analysis of lactate dehydrogenase, beta-glucuronidase and arylsulphatase in human gingival crevicular fluid collected with filter-paper strips
    • Lamster IB, Hartley LJ, Oshrain RL. Evaluation and modification of spectrophotometric procedures for analysis of lactate dehydrogenase, beta-glucuronidase and arylsulphatase in human gingival crevicular fluid collected with filter-paper strips. Arch Oral Biol 1985;30:235-242.
    • (1985) Arch Oral Biol , vol.30 , pp. 235-242
    • Lamster, I.B.1    Hartley, L.J.2    Oshrain, R.L.3
  • 37
    • 0002641211 scopus 로고
    • Method of collection
    • Basel, Switzerland: S. Karger;
    • Cimasoni G. Method of collection. In: Crevicular Fluid Updated. Basel, Switzerland: S. Karger; 1983:29-36.
    • (1983) Crevicular Fluid Updated , pp. 29-36
    • Cimasoni, G.1
  • 38
    • 0026812448 scopus 로고
    • Periodontal response to mechanical non-surgical therapy: A review
    • Greenstein G. Periodontal response to mechanical non-surgical therapy: A review. J Periodontol 1992; 63:118-130.
    • (1992) J Periodontol , vol.63 , pp. 118-130
    • Greenstein, G.1
  • 40
    • 0642280644 scopus 로고    scopus 로고
    • Matrix-degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate
    • Nordskog BK, Blixt AD, Morgan WT, Fields WR, Hellman GM. Matrix-degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate. Cardiovasc Toxicol 2003;3:101-117.
    • (2003) Cardiovasc Toxicol , vol.3 , pp. 101-117
    • Nordskog, B.K.1    Blixt, A.D.2    Morgan, W.T.3    Fields, W.R.4    Hellman, G.M.5
  • 42
    • 4644370370 scopus 로고    scopus 로고
    • Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: A multicenter trial
    • Preshaw PM, Hefti AF, Novak MJ, et al. Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: A multicenter trial. J Periodontol 2004;75:1068-1076.
    • (2004) J Periodontol , vol.75 , pp. 1068-1076
    • Preshaw, P.M.1    Hefti, A.F.2    Novak, M.J.3
  • 45
    • 18044404771 scopus 로고    scopus 로고
    • Subantimicrobial dose doxycycline as an adjunct to scaling and root planing: Post-treatment effects
    • Caton JG, Ciancio SG, Blieden TM, et al. Subantimicrobial dose doxycycline as an adjunct to scaling and root planing: Post-treatment effects. J Clin Periodontol 2001;28:782-789.
    • (2001) J Clin Periodontol , vol.28 , pp. 782-789
    • Caton, J.G.1    Ciancio, S.G.2    Blieden, T.M.3
  • 46
    • 0036048123 scopus 로고    scopus 로고
    • Adjunctive benefits of subantimicrobial dose doxycycline in the management of severe, generalized, chronic periodontitis
    • Novak MJ, Johns LP, Miller RC, Bradshaw MH. Adjunctive benefits of subantimicrobial dose doxycycline in the management of severe, generalized, chronic periodontitis. J Periodontol 2002;73:762-769.
    • (2002) J Periodontol , vol.73 , pp. 762-769
    • Novak, M.J.1    Johns, L.P.2    Miller, R.C.3    Bradshaw, M.H.4
  • 47
    • 16244405537 scopus 로고    scopus 로고
    • Adjunctive sub-antimicrobial dose doxycycline: Effect on clinical parameters and gingival crevicular fluid transforming growth factor-beta levels in severe, generalized chronic periodontitis
    • Gürkan A, Çinarcik S, Hüseyinov A. Adjunctive sub-antimicrobial dose doxycycline: Effect on clinical parameters and gingival crevicular fluid transforming growth factor-beta levels in severe, generalized chronic periodontitis. J Clin Periodontol 2005;32:244-253.
    • (2005) J Clin Periodontol , vol.32 , pp. 244-253
    • Gürkan, A.1    Çinarcik, S.2    Hüseyinov, A.3
  • 48
    • 0030138722 scopus 로고    scopus 로고
    • The "cyclic" regimen of low-dose doxycycline for adult periodontitis: A preliminary study
    • Crout RJ, Lee HM, Schroeder K, et al. The "cyclic" regimen of low-dose doxycycline for adult periodontitis: A preliminary study. J Periodontol 1996;67:506-514.
    • (1996) J Periodontol , vol.67 , pp. 506-514
    • Crout, R.J.1    Lee, H.M.2    Schroeder, K.3
  • 49
    • 0026824718 scopus 로고
    • Host modulation with tetracyclines and their chemically modified analogues
    • Golub LM, Suomalainen K, Sorsa T. Host modulation with tetracyclines and their chemically modified analogues. Curr Opin Dent 1992;2:80-90.
    • (1992) Curr Opin Dent , vol.2 , pp. 80-90
    • Golub, L.M.1    Suomalainen, K.2    Sorsa, T.3
  • 50
    • 0027481430 scopus 로고
    • Tetracycline inhibition and the cellular source of collagenase in gingival crevicular fluid in different periodontal diseases. A review article
    • Ingman T, Sorsa T, Suomalainen K, et al. Tetracycline inhibition and the cellular source of collagenase in gingival crevicular fluid in different periodontal diseases. A review article. J Periodontol 1993;64:82-88.
    • (1993) J Periodontol , vol.64 , pp. 82-88
    • Ingman, T.1    Sorsa, T.2    Suomalainen, K.3
  • 51
    • 0025845868 scopus 로고
    • Topical application of doxycycline on periodontally involved root surfaces in vitro: Comparative analysis of substantivity on cementum and dentin
    • Demirel K, Baer PN, McNamara TF. Topical application of doxycycline on periodontally involved root surfaces in vitro: Comparative analysis of substantivity on cementum and dentin. J Periodontol 1991;62:312-316.
    • (1991) J Periodontol , vol.62 , pp. 312-316
    • Demirel, K.1    Baer, P.N.2    McNamara, T.F.3
  • 52
    • 0029092082 scopus 로고
    • Evaluation of periodontal treatments using controlled-release tetracycline fibers: Maintenance response
    • Michalowicz BS, Pihlstrom BL, Drisko CL, et al. Evaluation of periodontal treatments using controlled-release tetracycline fibers: Maintenance response. J Periodontol 1995;66:708-715.
    • (1995) J Periodontol , vol.66 , pp. 708-715
    • Michalowicz, B.S.1    Pihlstrom, B.L.2    Drisko, C.L.3
  • 53
    • 18044404771 scopus 로고    scopus 로고
    • Subantimicrobial dose doxycycline as an adjunct to scaling and root planing: Post-treatment effects
    • Caton JG, Ciancio SG, Blieden TM, et al. Subantimicrobial dose doxycycline as an adjunct to scaling and root planing: Post-treatment effects. J Clin Periodontol 2001;28:782-789.
    • (2001) J Clin Periodontol , vol.28 , pp. 782-789
    • Caton, J.G.1    Ciancio, S.G.2    Blieden, T.M.3


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