Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice

Nature Communications

Volumn 6, Issue , 2015, Pages

  Singh, Nikhlesh K ^a   Kotla, Sivareddy ^a   Dyukova, Elena ^a   Traylor, James G ^a   Orr, A Wayne ^a   Chernoff, Jonathan ^b   Marion, Tony N ^a   Rao, Gadiparthi N ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HIGH DENSITY LIPOPROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN; P21 ACTIVATED KINASE 1; RANTES; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; CCL2 PROTEIN, MOUSE; P21 ACTIVATED KINASE; PAK1 PROTEIN, HUMAN; PAK1 PROTEIN, MOUSE;

ADHESION; CARDIOVASCULAR DISEASE; ENZYME ACTIVITY; GENE EXPRESSION; GERM CELL; PHOSPHATE; PROTEIN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ROOT; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL ADHESION; CELL MIGRATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GENE; GENE DISRUPTION; HUMAN; HUMAN TISSUE; LIPID BLOOD LEVEL; MACROPHAGE FUNCTION; MALE; MONOCYTE; MOUSE; NONHUMAN; P21 ACTIVATED KINASE 1 GENE; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; VASCULAR SMOOTH MUSCLE CELL; WESTERN DIET; ANIMAL; ARTERY; CELL MOTION; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MIDDLE AGED; SMOOTH MUSCLE CELL; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; YOUNG ADULT;

MUS;

ADULT; AGED; ANIMALS; APOLIPOPROTEINS E; ARTERIES; ATHEROSCLEROSIS; BLOTTING, WESTERN; CELL ADHESION; CELL MOVEMENT; CHEMOKINE CCL2; CHOLESTEROL; FEMALE; HUMANS; INTERLEUKIN-6; LIPOPROTEINS, LDL; MACROPHAGES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; P21-ACTIVATED KINASES; PLAQUE, ATHEROSCLEROTIC; YOUNG ADULT;

EID: 84933073691     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8450     Document Type: Article

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