Overview of hydrogel-based strategies for application in cardiac tissue regeneration

Biomedical Materials (Bristol)

Volumn 10, Issue 3, 2015, Pages

  Sun, Xuetao ^a   Nunes, Sara S ^a,b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

cardiac; cell therapy; hydrogels; stem cells; tissue regeneration

Indexed keywords

CARDIOLOGY; CELLS; CYTOLOGY; HEART; HYDROGELS; STEM CELLS; TISSUE;

CARDIAC; CARDIAC FUNCTIONS; CARDIO-VASCULAR DISEASE; CELL DELIVERY; CELL LOSS; CELL THERAPY; CELL TRANSPLANTATION; MYOCARDIAL INFARCTION;

TISSUE REGENERATION;

BIOMATERIAL; HYDROGEL;

BONE MARROW DERIVED MONONUCLEAR CELL; CARDIOVASCULAR DISEASE; CELL LOSS; CELL THERAPY; CELL TRANSPLANTATION; ENDOTHELIAL PROGENITOR CELL; FOLLOW UP; HEART; HEART EJECTION FRACTION; HEART FUNCTION; HUMAN; HYDROGEL; MESENCHYMAL STEM CELL; REVIEW; TISSUE REGENERATION; ADULT; ANIMAL; CARDIAC MUSCLE CELL; DISEASE MODEL; MATERIALS TESTING; MYOCARDIAL INFARCTION; PATHOPHYSIOLOGY; PHYSIOLOGY; REGENERATION; REGENERATIVE MEDICINE; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING; TRANSPLANTATION;

ADULT; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL TRANSPLANTATION; DISEASE MODELS, ANIMAL; HEART; HUMANS; HYDROGELS; MATERIALS TESTING; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; REGENERATION; REGENERATIVE MEDICINE; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING;

EID: 84933049191     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/10/3/034005     Document Type: Review

References (101)

1. Ahuja P, Sdek P and MacLellan W R 2007 Cardiac myocyte cell cycle control in development, disease, and regeneration Physiol. Rev. 87 521-44
2. Xin M, Olson E N and Bassel-Duby R 2013 Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair Nat. Rev. Mol. Cell Biol. 14 529-41
3. Heineke J and Molkentin J D 2006 Regulation of cardiac hypertrophy by intracellular signalling pathways Nat. Rev. Mol. Cell Biol. 7 589-600
4. Roger V L et al 2012 Heart disease and stroke statistics - 2012 update: a report from the American Heart Association Circulation 125 e2-220
5. Kirklin J K et al 2013 Fifth INTERMACS annual report: risk factor analysis from more than 6000 mechanical circulatory support patients J. Heart Lung. Transplant. 32 141-56
6. Ogawa R, Stachnik J M and Echizen H 2013 Clinical pharmacokinetics of drugs in patients with heart failure: an update (part 1, drugs administered intravenously) Clin. Pharmacokinet. 52 169-85
7. Reis L A, Chiu L L Y, Feric N, Fu L and Radisic M 2014 Biomaterials in myocardial tissue engineering J. Tissue Eng. Regen. Med. at press (doi:10.1002/term.1944)
8. Tomita S et al 1999 Autologous transplantation of bone marrow cells improves damaged heart function Circulation 100 II-247-56
9. Orlic D et al 2001 Bone marrow cells regenerate infarcted myocardium Nature 410 701-5
10. Orlic D et al 2001 Mobilized bone marrow cells repair the infarcted heart, improving function and survival Proc. Natl Acad. Sci. USA 98 10344-9
11. Kamihata H et al 2001 Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokines Circulation 104 1046-52
12. Silva G V et al 2005 Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model Circulation 111 150-6
13. Tang J et al 2006 Mesenchymal stem cells participate in angiogenesis and improve heart function in rat model of myocardial ischemia with reperfusion Eur. J. Cardiothorac. Surg. 30 353-61
14. Ellison G M et al 2013 Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair Cell 154 827-42
15. Assmus B et al 2002 Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI) Circulation 106 3009-17
16. Schachinger V et al 2006 Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction New Engl. J. Med. 355 1210-21
17. Wollert K C et al 2004 Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial Lancet 364 141-8
18. Huikuri H V et al 2008 Effects of intracoronary injection of mononuclear bone marrow cells on left ventricular function, arrhythmia risk profile, and restenosis after thrombolytic therapy of acute myocardial infarction Eur. Heart J. 29 2723-32
19. Bolli R et al 2011 Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial Lancet 378 1847-57
20. Makkar R R et al 2012 Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial Lancet 379 895-904
21. Bartunek J et al 2013 Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics J. Am. Coll. Cardiol. 61 2329-38
22. Wohrle J et al 2010 Results of intracoronary stem cell therapy after acute myocardial infarction Am. J. Cardiol. 105 804-12
23. Peppas N A et al 2006 Hydrogels in biology and medicine: from molecular principles to bionanotechnology Adv. Mater. 18 1345-60
24. Jeong B, Kim S W and Bae Y H 2002 Thermosensitive sol-gel reversible hydrogels Adv. Drug Deliv. Rev. 54 37-51
25. Slaughter B V et al 2009 Hydrogels in regenerative medicine Adv. Mater. 21 3307-29
26. Li Z and Guan J 2011 Hydrogels for cardiac tissue engineering Polymers 3 740-61
27. Johnson T D and Christman K L 2013 Injectable hydrogel therapies and their delivery strategies for treating myocardial infarction Expert Opin. Drug Deliv. 10 59-72
28. Radhakrishnan J, Krishnan U M and Sethuraman S 2014 Hydrogel based injectable scaffolds for cardiac tissue regeneration Biotechnol. Adv. 32 449-61
29. Tous E et al 2011 Injectable acellular hydrogels for cardiac repair J. Cardiovasc. Transl. Res. 4 528-42
30. Mercola M, Ruiz-Lozano P and Schneider M D 2011 Cardiac muscle regeneration: lessons from development Genes. Dev. 25 299-309
31. Kanashiro-Takeuchi R M et al 2010 Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction Proc. Natl Acad. Sci. USA 107 2604-9
32. Kanashiro-Takeuchi R M et al 2012 Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI) Proc. Natl Acad. Sci. USA 109 559-63
33. Koudstaal S et al 2014 Sustained delivery of insulin-like growth factor-1/hepatocyte growth factor stimulates endogenous cardiac repair in the chronic infarcted pig heart J. Cardiovasc. Transl. Res. 7 232-41
34. Zhao Z Q et al 2010 Improvement in cardiac function with small intestine extracellular matrix is associated with recruitment of C-kit cells, myofibroblasts, and macrophages after myocardial infarction J. Am. Coll. Cardiol. 55 1250-61
35. Shaikh F M et al 2008 Fibrin: a natural biodegradable scaffold in vascular tissue engineering Cells Tissues Organs. 188 333-46
36. Christman K L et al 2004 Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction Tissue Eng. 10 403-9
37. Christman K L et al 2004 Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium J. Am. Coll. Cardiol. 44 654-60
38. Hall H, Baechi T and Hubbell J A 2001 Molecular properties of fibrin-based matrices for promotion of angiogenesis in vitro Microvasc. Res. 62 315-26
39. Sahni A, Odrljin T and Francis C W 1998 Binding of basic fibroblast growth factor to fibrinogen and fibrin J. Biol. Chem. 273 7554-9
40. Bootle-Wilbraham C A et al 2001 Fibrin fragment E stimulates the proliferation, migration and differentiation of human microvascular endothelial cells in vitro Angiogenesis 4 269-75
41. Yu J et al 2009 Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy J. Thorac. Cardiovasc. Surg. 137 180-7
42. Huang N F et al 2005 Injectable biopolymers enhance angiogenesis after myocardial infarction Tissue Eng. 11 1860-6
43. Fujimoto K L et al 2009 Synthesis, characterization and therapeutic efficacy of a biodegradable, thermoresponsive hydrogel designed for application in chronic infarcted myocardium Biomaterials 30 4357-68
44. Singelyn J M et al 2009 Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering Biomaterials 30 5409-16
45. Serpooshan V et al 2013 The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function post myocardial infarction Biomaterials 34 9048-55
46. Rane A A et al 2011 Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction PLoS One 6 e21571
47. Garbern J C et al 2011 Delivery of basic fibroblast growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis in infarcted myocardium Biomaterials 32 2407-16
48. Ou L et al 2011 Intracardiac injection of matrigel induces stem cell recruitment and improves cardiac functions in a rat myocardial infarction model J. Cell. Mol. Med. 15 1310-8
49. Singelyn J M et al 2012 Catheter-deliverable hydrogel derived from decellularized ventricular extracellular matrix increases endogenous cardiomyocytes and preserves cardiac function post-myocardial infarction J. Am. Coll. Cardiol. 59 751-63
50. Seif-Naraghi S B et al 2013 Safety and efficacy of an injectable extracellular matrix hydrogel for treating myocardial infarction Sci. Transl. Med. 5 173ra25
51. Landa N et al 2008 Effect of injectable alginate implant on cardiac remodeling and function after recent and old infarcts in rat Circulation 117 1388-96
52. Leor J et al 2009 Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in Swine J. Am. Coll. Cardiol. 54 1014-23
53. Lee L C et al 2013 Algisyl-LVR with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart Int. J. Cardiol. 168 2022-8
54. MacArthur J W Jr et al 2013 Sustained release of engineered stromal cell-derived factor 1-alpha from injectable hydrogels effectively recruits endothelial progenitor cells and preserves ventricular function after myocardial infarction Circulation 128 S79-86
55. Habib M et al 2011 A combined cell therapy and in situ tissue-engineering approach for myocardial repair Biomaterials 32 7514-23
56. Rufaihah A J et al 2013 Enhanced infarct stabilization and neovascularization mediated by VEGF-loaded PEGylated fibrinogen hydrogel in a rodent myocardial infarction model Biomaterials 34 8195-202
57. Cuende N, Rico L and Herrera C 2012 Concise review: bone marrow mononuclear cells for the treatment of ischemic syndromes: medicinal product or cell transplantation? Stem. Cells Transl. Med. 1 403-8
58. Hastings C L et al 2015 Drug and cell delivery for cardiac regeneration Adv. Drug Deliv. Rev. 84 85-106
59. Chen C H et al 2013 Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction Mol. Ther. 21 670-9
60. Chen C H et al 2014 Injection of autologous bone marrow cells in hyaluronan hydrogel improves cardiac performance after infarction in pigs Am. J. Physiol. Heart Circ. Physiol. 306 H1078-86
61. Li X Y et al 2010 Injectable hydrogel helps bone marrow-derived mononuclear cells restore infarcted myocardium Cardiology 115 194-9
62. Meyer G P et al 2006 Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial Circulation 113 1287-94
63. Delewi R et al 2013 Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a meta-analysis of randomised controlled clinical trials Heart 99 225-32
64. Jeevanantham V et al 2012 Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis Circulation 126 551-68
65. Leistner D M et al 2011 Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5 year results suggest long-term safety and efficacy Clin. Res. Cardiol. 100 925-34
66. Assmus B et al 2014 Long-term clinical outcome after intracoronary application of bone marrow-derived mononuclear cells for acute myocardial infarction: migratory capacity of administered cells determines event-free survival Eur. Heart J. 35 1275-83
67. Meyer G P et al 2009 Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial Eur. Heart J. 30 2978-84
68. Lunde K et al 2006 Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction New Engl. J. Med. 355 1199-209
69. Hirsch A et al 2011 Intracoronary infusion of mononuclear cells from bone marrow or peripheral blood compared with standard therapy in patients after acute myocardial infarction treated by primary percutaneous coronary intervention: results of the randomized controlled HEBE trial Eur. Heart J. 32 1736-47
70. Tang Y L et al 2004 Autologous mesenchymal stem cell transplantation induce VEGF and neovascularization in ischemic myocardium Regul. Pept. 117 3-10
71. Kinnaird T et al 2004 Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms Circulation 109 1543-9
72. Uemura R et al 2006 Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling Circ. Res. 98 1414-21
73. Mirotsou M et al 2007 Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair Proc. Natl Acad. Sci. USA 104 1643-8
74. Gnecchi M et al 2008 Paracrine mechanisms in adult stem cell signaling and therapy Circ. Res. 103 1204-19
75. Malliaras K and Marban E 2011 Cardiac cell therapy: where we've been, where we are, and where we should be headed Br. Med. Bull. 98 161-85
76. Mangi A A et al 2003 Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts Nat. Med. 9 1195-201
77. Kinnaird T et al 2004 Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms Circ. Res. 94 678-85
78. Rehman J et al 2004 Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells Circulation 109 1292-8
79. Aggarwal S and Pittenger M F 2005 Human mesenchymal stem cells modulate allogeneic immune cell responses Blood 105 1815-22
80. Caplan A I and Dennis J E 2006 Mesenchymal stem cells as trophic mediators J. Cell Biochem. 98 1076-84
81. Berry M F et al 2006 Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance Am. J. Physiol. Heart Circ. Physiol. 290 H2196-203
82. Martens T P et al 2009 Percutaneous cell delivery into the heart using hydrogels polymerizing in situ Cell Transplant. 18 297-304
83. Levit R D et al 2013 Cellular encapsulation enhances cardiac repair J. Am. Heart Assoc. 2 e000367
84. Mathieu E et al 2012 Intramyocardial delivery of mesenchymal stem cell-seeded hydrogel preserves cardiac function and attenuates ventricular remodeling after myocardial infarction PLoS One 7 e51991
85. Xu G et al 2015 Injectable biodegradable hybrid hydrogels based on thiolated collagen and oligo(acryloyl carbonate)-poly(ethylene glycol)-oligo(acryloyl carbonate) copolymer for functional cardiac regeneration Acta Biomater. 15 55-64
86. Godier-Furnemont A F et al 2011 Composite scaffold provides a cell delivery platform for cardiovascular repair Proc. Natl Acad. Sci. USA 108 7974-9
87. Laflamme M A et al 2007 Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts Nat. Biotechnol. 25 1015-24
88. Mummery C et al 2003 Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells Circulation 107 2733-40
89. Gwak S J et al 2008 The effect of cyclic strain on embryonic stem cell-derived cardiomyocytes Biomaterials 29 844-56
90. Sawa Y and Miyagawa S 2013 Present and future perspectives on cell sheet-based myocardial regeneration therapy Biomed. Res. Int. 2013 583912
91. Shimizu T et al 2003 Cell sheet engineering for myocardial tissue reconstruction Biomaterials 24 2309-16
92. Kawamura M et al 2012 Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model Circulation 126 S29-37
93. Miki K et al 2012 Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats Stem Cells Transl. Med. 1 430-7
94. Dvir T et al 2009 Prevascularization of cardiac patch on the omentum improves its therapeutic outcome Proc. Natl Acad. Sci. USA 106 14990-5
95. Takehara N et al 2008 Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction J. Am. Coll. Cardiol. 52 1858-65
96. Shafy A et al 2013 Development of cardiac support bioprostheses for ventricular restoration and myocardial regeneration Eur. J. Cardiothorac. Surg. 43 1211-9
97. Kraehenbuehl T P et al 2011 Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction Biomaterials 32 1102-9
98. Heymans S et al 1999 Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure Nat. Med. 5 1135-42
99. Fernandes S et al 2010 Human embryonic stem cell-derived cardiomyocytes engraft but do not alter cardiac remodeling after chronic infarction in rats J. Mol. Cell Cardiol. 49 941-9
100. Chong J J et al 2014 Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts Nature 510 273-7
101. Radisic M and Christman K L 2013 Materials science and tissue engineering: repairing the heart Mayo Clin. Proc. 88 884-98