Sclareol exerts anti-osteoarthritic activities in interleukin-1β-induced rabbit chondrocytes and a rabbit osteoarthritis model

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 3, 2015, Pages 2365-2374

  Zhong, Ying ^a   Huang, Yi ^a   Santoso, Marcel B ^a   Wu, Li Dong ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

ACLT; Matrix metalloproteinase; Nitric oxide; Osteoarthritis; Sclareol

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; DITERPENE; IL1B PROTEIN, HUMAN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E2; SCLAREOL; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL; ARTICULAR CARTILAGE; CELL CULTURE; CHONDROCYTE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; INTRAARTICULAR DRUG ADMINISTRATION; JOINT; METABOLISM; OSTEOARTHRITIS; PATHOLOGY; RABBIT; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; CYCLOOXYGENASE 2; DINOPROSTONE; DISEASE MODELS, ANIMAL; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; INJECTIONS, INTRA-ARTICULAR; INTERLEUKIN-1BETA; JOINTS; MATRIX METALLOPROTEINASES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OSTEOARTHRITIS; RABBITS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 84933034818     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

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