Labd-14-ene-8,13-diol (sclareol) induces cell cycle arrest and apoptosis in human breast cancer cells and enhances the activity of anticancer drugs

Biomedicine and Pharmacotherapy

Volumn 60, Issue 3, 2006, Pages 127-133

  Dimas, K ^a   Papadaki, M ^a   Tsimplouli, C ^a   Hatziantoniou, S ^b   Alevizopoulos, K ^c   Pantazis, P ^a,d   Demetzos, C ^b  

^a BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c Medexis Biotech SA   (Greece)

^d UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

Apoptosis; Breast cancer cells; Labdane diterpenes; p53; Sclareol

Indexed keywords

CISPLATIN; DNA FRAGMENT; DOXORUBICIN; ETOPOSIDE; PROTEIN P53; SCLAREOL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG ACTIVITY; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; FLOW INJECTION ANALYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG INTERACTIONS; ETOPOSIDE; FEMALE; G0 PHASE; G1 PHASE; HUMANS; S PHASE; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33645417223     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2006.01.003     Document Type: Article

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