Contribution of H3K4 methylation by SET-1A to interleukin-1-induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes

Arthritis and Rheumatism

Volumn 63, Issue 1, 2011, Pages 168-179

  El Mansouri, Fatima Ezzahra ^a   Chabane, Nadir ^a   Zayed, Nadia ^a   Kapoor, Mohit ^a   Benderdour, Mohamed ^b   Martel Pelletier, Johanne ^a   Pelletier, Jean Pierre ^a   Duval, Nicolas ^c   Fahmi, Hassan ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c Duval Orthopaedic Clinic   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; HISTONE H3; HISTONE H3 LYSINE 4; HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE SET 1A; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; METHYLTRANSFERASE INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CARTILAGE CELL; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; GENE SILENCING; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING;

EID: 78650783194     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27762     Document Type: Article

References (49)

1. Lawrence RC, Helmick CG, Arnett FC, Deyo RA, Felson DT, Giannini EH, et al. Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 1998; 41: 778-99.
2. Goldring MB, Berenbaum F,. The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide. Clin Orthop Relat Res 2004; 427 Suppl: S37-46.
3. Goldring MB, Marcu KB,. Cartilage homeostasis in health and rheumatic diseases. Arthritis Res Ther 2009; 11: 224.
4. Abramson SB, Attur M,. Developments in the scientific understanding of osteoarthritis. Arthritis Res Ther 2009; 11: 227.
5. McInnes IB, Leung BP, Field M, Wei XQ, Huang FP, Sturrock RD, et al. Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. J Exp Med 1996; 184: 1519-24.
6. Scher JU, Pillinger MH, Abramson SB,. Nitric oxide synthases and osteoarthritis. Curr Rheumatol Rep 2007; 9: 9-15.
7. Hashimoto S, Takahashi K, Amiel D, Coutts RD, Lotz M,. Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis. Arthritis Rheum 1998; 41: 1266-74.
8. Sasaki K, Hattori T, Fujisawa T, Takahashi K, Inoue H, Takigawa M,. Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes. J Biochem 1998; 123: 431-9.
9. Taskiran D, Stefanovic-Racic M, Georgescu H, Evans C,. Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1. Biochem Biophys Res Commun 1994; 200: 142-8.
10. Tetsuka T, Daphna-Iken D, Miller BW, Guan Z, Baier LD, Morrison AR,. Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells. J Clin Invest 1996; 97: 2051-6.
11. Pelletier JP, Mineau F, Ranger P, Tardif G, Martel-Pelletier J,. The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation. Osteoarthritis Cartilage 1996; 4: 77-84.
12. Pelletier JP, Jovanovic D, Fernandes JC, Manning P, Connor JR, Currie MG, et al. Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase. Arthritis Rheum 1998; 41: 1275-86.
13. Sadowski T, Steinmeyer J,. Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1, matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes. Osteoarthritis Cartilage 2001; 9: 407-15.
14. Hiroi M, Ohmori Y,. The transcriptional coactivator CREB-binding protein cooperates with STAT1 and NF-ÎB for synergistic transcriptional activation of the CXC ligand 9/monokine induced by interferon-γ gene. J Biol Chem 2003; 278: 651-60.
15. 2 modulates cartilage proteoglycan degradation in human osteoarthritis explants. Arthritis Rheum 2002; 46: 1789-803.
16. 2 through cAMP-dependent pathway. Osteoarthritis Cartilage 2000; 8: 17-24.
17. Martel-Pelletier J, Pelletier JP, Fahmi H,. Cyclooxygenase-2 and prostaglandins in articular tissues. Semin Arthritis Rheum 2003; 33: 155-67.
18. Amin AR, Attur M, Patel RN, Thakker GD, Marshall PJ, Rediske J, et al. Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage: influence of nitric oxide. J Clin Invest 1997; 99: 1231-7.
19. Kouzarides T,. Chromatin modifications and their function. Cell 2007; 128: 693-705.
20. Munshi A, Shafi G, Aliya N, Jyothy A,. Histone modifications dictate specific biological readouts. J Genet Genomics 2009; 36: 75-88.
21. Martin C, Zhang Y,. The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol 2005; 6: 838-49.
22. Volkel P, Angrand PO,. The control of histone lysine methylation in epigenetic regulation. Biochimie 2007; 89: 1-20.
23. Shilatifard A,. Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Curr Opin Cell Biol 2008; 20: 341-8.
24. Sims RJ III, Reinberg D,. Histone H3 Lys 4 methylation: caught in a bind? Genes Dev 2006; 20: 2779-86.
25. Santos-Rosa H, Schneider R, Bannister AJ, Sherriff J, Bernstein BE, Emre NC, et al. Active genes are tri-methylated at K4 of histone H3. Nature 2002; 419: 407-11.
26. Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W,. Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev 2003; 17: 896-911.
27. Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, et al. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol 2006; 13: 713-9.
28. Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, et al. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Mol Cell Biol 2009; 29: 6074-85.
29. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986; 29: 1039-49.
30. Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, et al. Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes. Arthritis Res Ther 2007; 9: R31.
31. Martens JH, Verlaan M, Kalkhoven E, Zantema A,. Cascade of distinct histone modifications during collagenase gene activation. Mol Cell Biol 2003; 23: 1808-16.
32. 2 through a histone deacetylase-independent mechanism. Arthritis Rheum 2005; 52: 94-104.
33. Chabane N, Li X, Fahmi H,. HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity. J Cell Biochem 2009; 106: 453-63.
34. Williams-Ashman HG, Seidenfeld J, Galletti P,. Trends in the biochemical pharmacology of 5â-deoxy-5â-methylthioadenosine. Biochem Pharmacol 1982; 31: 277-88.
35. Li Y, Reddy MA, Miao F, Shanmugam N, Yee JK, Hawkins D, et al. Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-ÎB-dependent inflammatory genes: relevance to diabetes and inflammation. J Biol Chem 2008; 283: 26771-81.
36. Ara AI, Xia M, Ramani K, Mato JM, Lu SC,. S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation. Hepatology 2008; 47: 1655-66.
37. Reddy MA, Villeneuve LM, Wang M, Lanting L, Natarajan R,. Role of the lysine-specific demethylase 1 in the proinflammatory phenotype of vascular smooth muscle cells of diabetic mice. Circ Res 2008; 103: 615-23.
38. Chou SD, Tomasi TB,. Spatial distribution of histone methylation during MHC class II expression. Mol Immunol 2008; 45: 971-80.
39. Akimzhanov AM, Yang XO, Dong C,. Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation. J Biol Chem 2007; 282: 5969-72.
40. Melchiorri C, Meliconi R, Frizziero L, Silvestri T, Pulsatelli L, Mazzetti I, et al. Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis. Arthritis Rheum 1998; 41: 2165-74.
41. Dumond H, Presle N, Pottie P, Pacquelet S, Terlain B, Netter P, et al. Site specific changes in gene expression and cartilage metabolism during early experimental osteoarthritis. Osteoarthritis Cartilage 2004; 12: 284-95.
42. Wang H, Cao R, Xia L, Erdjument-Bromage H, Borchers C, Tempst P, et al. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. Mol Cell 2001; 8: 1207-17.
43. Zegerman P, Canas B, Pappin D, Kouzarides T,. Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. J Biol Chem 2002; 277: 11621-4.
44. Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, et al. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 2006; 442: 86-90.
45. Pray-Grant MG, Daniel JA, Schieltz D, Yates JR III, Grant PA,. Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation. Nature 2005; 433: 434-8.
46. Vermeulen M, Mulder KW, Denissov S, Pijnappel WW, van Schaik FM, Varier RA, et al. Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell 2007; 131: 58-69.
47. Hampsey M, Reinberg D,. Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation. Cell 2003; 113: 429-32.
48. Lee YH, Stallcup MR,. Minireview: protein arginine methylation of nonhistone proteins in transcriptional regulation. Mol Endocrinol 2009; 23: 425-33.
49. Yang XD, Huang B, Li M, Lamb A, Kelleher NL, Chen LF,. Negative regulation of NF-ÎB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J 2009; 28: 1055-66.