메뉴 건너뛰기




Volumn 195, Issue 1, 2015, Pages 194-202

Deficiency of CD40 reveals an important role for LIGHT in anti-leishmania immunity

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD8ALPHA ANTIGEN; GAMMA INTERFERON; HERPESVIRUS ENTRY MEDIATOR; IMMUNOGLOBULIN; INTERLEUKIN 12; LIGHT PROTEIN; LYMPHOTOXIN BETA RECEPTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CD8 ANTIGEN; HERPESVIRUS ENTRY MEDIATOR LIGAND; TNFSF14 PROTEIN, MOUSE;

EID: 84932185692     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401892     Document Type: Article
Times cited : (9)

References (51)
  • 1
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • Reiner, S. L., and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13: 151-177.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 151-177
    • Reiner, S.L.1    Locksley, R.M.2
  • 2
    • 0029937829 scopus 로고    scopus 로고
    • Th cell development and regulation in experimental cutaneous leishmaniasis
    • Scott, P. 1996. Th cell development and regulation in experimental cutaneous leishmaniasis. Chem. Immunol. 63: 98-114.
    • (1996) Chem. Immunol. , vol.63 , pp. 98-114
    • Scott, P.1
  • 3
    • 0027488625 scopus 로고
    • Helper T cells without CD4: Control of leishmaniasis in CD4-deficient mice
    • Locksley, R. M., S. L. Reiner, F. Hatam, D. R. Littman, and N. Killeen. 1993. Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice. Science 261: 1448-1451.
    • (1993) Science , vol.261 , pp. 1448-1451
    • Locksley, R.M.1    Reiner, S.L.2    Hatam, F.3    Littman, D.R.4    Killeen, N.5
  • 8
    • 0031756309 scopus 로고    scopus 로고
    • Anti-leishmania effector functions of CD4+ Th1 cells and early events instructing Th2 cell development and susceptibility to Leishmania major in BALB/c mice
    • Louis, J. A., F. Conceic?ao-Silva, H. Himmelrich, F. Tacchini-Cottier, and P. Launois. 1998. Anti-leishmania effector functions of CD4+ Th1 cells and early events instructing Th2 cell development and susceptibility to Leishmania major in BALB/c mice. Adv. Exp. Med. Biol. 452: 53-60.
    • (1998) Adv. Exp. Med. Biol. , vol.452 , pp. 53-60
    • Louis, J.A.1    Conceicao-Silva, F.2    Himmelrich, H.3    Tacchini-Cottier, F.4    Launois, P.5
  • 9
    • 0032403583 scopus 로고    scopus 로고
    • The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12
    • Himmelrich, H., C. Parra-Lopez, F. Tacchini-Cottier, J. A. Louis, and P. Launois. 1998. The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12. J. Immunol. 161: 6156-6163.
    • (1998) J. Immunol. , vol.161 , pp. 6156-6163
    • Himmelrich, H.1    Parra-Lopez, C.2    Tacchini-Cottier, F.3    Louis, J.A.4    Launois, P.5
  • 10
    • 0031820396 scopus 로고    scopus 로고
    • Differential regulation of the interleukin-12 receptor during the innate immune response to Leishmania major
    • Jones, D., M. M. Elloso, L. Showe, D. Williams, G. Trinchieri, and P. Scott. 1998. Differential regulation of the interleukin-12 receptor during the innate immune response to Leishmania major. Infect. Immun. 66: 3818-3824.
    • (1998) Infect. Immun. , vol.66 , pp. 3818-3824
    • Jones, D.1    Elloso, M.M.2    Showe, L.3    Williams, D.4    Trinchieri, G.5    Scott, P.6
  • 12
    • 0029925517 scopus 로고    scopus 로고
    • Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection
    • Soong, L., J. C. Xu, I. S. Grewal, P. Kima, J. Sun, B. J. Longley, Jr., N. H. Ruddle, D. McMahon-Pratt, and R. A. Flavell. 1996. Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity 4: 263-273.
    • (1996) Immunity , vol.4 , pp. 263-273
    • Soong, L.1    Xu, J.C.2    Grewal, I.S.3    Kima, P.4    Sun, J.5    Longley, B.J.6    Ruddle, N.H.7    McMahon-Pratt, D.8    Flavell, R.A.9
  • 13
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley, R. M., N. Killeen, and M. J. Lenardo. 2001. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104: 487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 14
    • 17644400505 scopus 로고    scopus 로고
    • Network communications: Lymphotoxins, LIGHT, and TNF
    • Ware, C. F. 2005. Network communications: lymphotoxins, LIGHT, and TNF. Annu. Rev. Immunol. 23: 787-819.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 787-819
    • Ware, C.F.1
  • 17
    • 0037982575 scopus 로고    scopus 로고
    • The role of lymphotoxin in development and maintenance of secondary lymphoid tissues
    • Tumanov, A. V., D. V. Kuprash, and S. A. Nedospasov. 2003. The role of lymphotoxin in development and maintenance of secondary lymphoid tissues. Cytokine Growth Factor Rev. 14: 275-288.
    • (2003) Cytokine Growth Factor Rev. , vol.14 , pp. 275-288
    • Tumanov, A.V.1    Kuprash, D.V.2    Nedospasov, S.A.3
  • 18
    • 0037644804 scopus 로고    scopus 로고
    • Biological functions of tumor necrosis factor cytokines and their receptors
    • Pfeffer, K. 2003. Biological functions of tumor necrosis factor cytokines and their receptors. Cytokine Growth Factor Rev. 14: 185-191.
    • (2003) Cytokine Growth Factor Rev. , vol.14 , pp. 185-191
    • Pfeffer, K.1
  • 20
    • 0032530318 scopus 로고    scopus 로고
    • LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer
    • Zhai, Y., R. Guo, T. L. Hsu, G. L. Yu, J. Ni, B. S. Kwon, G. W. Jiang, J. Lu, J. Tan, M. Ugustus, et al. 1998. LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer. J. Clin. Invest. 102: 1142-1151.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1142-1151
    • Zhai, Y.1    Guo, R.2    Hsu, T.L.3    Yu, G.L.4    Ni, J.5    Kwon, B.S.6    Jiang, G.W.7    Lu, J.8    Tan, J.9    Ugustus, M.10
  • 21
    • 0034655166 scopus 로고    scopus 로고
    • LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response
    • Tamada, K., K. Shimozaki, A. I. Chapoval, Y. Zhai, J. Su, S. F. Chen, S. L. Hsieh, S. Nagata, J. Ni, and L. Chen. 2000. LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response. J. Immunol. 164: 4105-4110.
    • (2000) J. Immunol. , vol.164 , pp. 4105-4110
    • Tamada, K.1    Shimozaki, K.2    Chapoval, A.I.3    Zhai, Y.4    Su, J.5    Chen, S.F.6    Hsieh, S.L.7    Nagata, S.8    Ni, J.9    Chen, L.10
  • 23
    • 0033553489 scopus 로고    scopus 로고
    • A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis
    • Yu, K. Y., B. Kwon, J. Ni, Y. Zhai, R. Ebner, and B. S. Kwon. 1999. A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis. J. Biol. Chem. 274: 13733-13736.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13733-13736
    • Yu, K.Y.1    Kwon, B.2    Ni, J.3    Zhai, Y.4    Ebner, R.5    Kwon, B.S.6
  • 24
    • 0030984895 scopus 로고    scopus 로고
    • A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation
    • Kwon, B. S., K. B. Tan, J. Ni, K. O. Oh, Z. H. Lee, K. K. Kim, Y. J. Kim, S. Wang, R. Gentz, G. L. Yu, et al. 1997. A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. J. Biol. Chem. 272: 14272-14276.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14272-14276
    • Kwon, B.S.1    Tan, K.B.2    Ni, J.3    Oh, K.O.4    Lee, Z.H.5    Kim, K.K.6    Kim, Y.J.7    Wang, S.8    Gentz, R.9    Yu, G.L.10
  • 25
    • 0034667773 scopus 로고    scopus 로고
    • Reciprocal expression of the TNF family receptor herpes virus entry mediator and its ligand LIGHT on activated T cells: LIGHT down-regulates its own receptor
    • Morel, Y., J. M. Schiano de Colella, J. Harrop, K. C. Deen, S. D. Holmes, T. A. Wattam, S. S. Khandekar, A. Truneh, R. W. Sweet, J. A. Gastaut, et al. 2000. Reciprocal expression of the TNF family receptor herpes virus entry mediator and its ligand LIGHT on activated T cells: LIGHT down-regulates its own receptor. J. Immunol. 165: 4397-4404.
    • (2000) J. Immunol. , vol.165 , pp. 4397-4404
    • Morel, Y.1    Schiano De Colella, J.M.2    Harrop, J.3    Deen, K.C.4    Holmes, S.D.5    Wattam, T.A.6    Khandekar, S.S.7    Truneh, A.8    Sweet, R.W.9    Gastaut, J.A.10
  • 26
    • 0141832116 scopus 로고    scopus 로고
    • Lymphotoxin/light, lymphoid microenvironments and autoimmune disease
    • Gommerman, J. L., and J. L. Browning. 2003. Lymphotoxin/light, lymphoid microenvironments and autoimmune disease. Nat. Rev. Immunol. 3: 642-655.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 642-655
    • Gommerman, J.L.1    Browning, J.L.2
  • 27
    • 27744442642 scopus 로고    scopus 로고
    • Stimulating lymphotoxin beta receptor on the dendritic cells is critical for their homeostasis and expansion
    • Wang, Y. G., K. D. Kim, J. Wang, P. Yu, and Y. X. Fu. 2005. Stimulating lymphotoxin beta receptor on the dendritic cells is critical for their homeostasis and expansion. J. Immunol. 175: 6997-7002.
    • (2005) J. Immunol. , vol.175 , pp. 6997-7002
    • Wang, Y.G.1    Kim, K.D.2    Wang, J.3    Yu, P.4    Fu, Y.X.5
  • 29
    • 0034117337 scopus 로고    scopus 로고
    • Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT costimulatory pathway
    • Tamada, K., K. Shimozaki, A. I. Chapoval, G. Zhu, G. Sica, D. Flies, T. Boone, H. Hsu, Y. X. Fu, S. Nagata, et al. 2000. Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT costimulatory pathway. Nat. Med. 6: 283-289.
    • (2000) Nat. Med. , vol.6 , pp. 283-289
    • Tamada, K.1    Shimozaki, K.2    Chapoval, A.I.3    Zhu, G.4    Sica, G.5    Flies, D.6    Boone, T.7    Hsu, H.8    Fu, Y.X.9    Nagata, S.10
  • 30
    • 0035576394 scopus 로고    scopus 로고
    • Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction
    • Shaikh, R. B., S. Santee, S. W. Granger, K. Butrovich, T. Cheung, M. Kronenberg, H. Cheroutre, and C. F. Ware. 2001. Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction. J. Immunol. 167: 6330-6337.
    • (2001) J. Immunol. , vol.167 , pp. 6330-6337
    • Shaikh, R.B.1    Santee, S.2    Granger, S.W.3    Butrovich, K.4    Cheung, T.5    Kronenberg, M.6    Cheroutre, H.7    Ware, C.F.8
  • 32
    • 38449084034 scopus 로고    scopus 로고
    • LIGHT is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major
    • Xu, G., D. Liu, I. Okwor, Y. Wang, H. Korner, S. K. Kung, Y. X. Fu, and J. E. Uzonna. 2007. LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major. J. Immunol. 179: 6901-6909.
    • (2007) J. Immunol. , vol.179 , pp. 6901-6909
    • Xu, G.1    Liu, D.2    Okwor, I.3    Wang, Y.4    Korner, H.5    Kung, S.K.6    Fu, Y.X.7    Uzonna, J.E.8
  • 33
    • 2942679337 scopus 로고    scopus 로고
    • Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon gamma-producing CD8+ T cells
    • Uzonna, J. E., K. L. Joyce, and P. Scott. 2004. Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon gamma-producing CD8+ T cells. J. Exp. Med. 199: 1559-1566.
    • (2004) J. Exp. Med. , vol.199 , pp. 1559-1566
    • Uzonna, J.E.1    Joyce, K.L.2    Scott, P.3
  • 34
    • 68149100422 scopus 로고    scopus 로고
    • The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells
    • Liu, D., T. Zhang, A. J. Marshall, K. Okkenhaug, B. Vanhaesebroeck, and J. E. Uzonna. 2009. The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells. J. Immunol. 183: 1921-1933.
    • (2009) J. Immunol. , vol.183 , pp. 1921-1933
    • Liu, D.1    Zhang, T.2    Marshall, A.J.3    Okkenhaug, K.4    Vanhaesebroeck, B.5    Uzonna, J.E.6
  • 35
    • 84920366926 scopus 로고    scopus 로고
    • CD8+ T cells are preferentially activated during primary low dose leishmania major infection but are completely dispensable during secondary anti-Leishmania immunity
    • Okwor, I. B., P. Jia, Z. Mou, C. Onyilagha, and J. E. Uzonna. 2014. CD8+ T cells are preferentially activated during primary low dose leishmania major infection but are completely dispensable during secondary anti-Leishmania immunity. PLoS Negl. Trop. Dis. 8: e3300.
    • (2014) PLoS Negl. Trop. Dis. , vol.8 , pp. e3300
    • Okwor, I.B.1    Jia, P.2    Mou, Z.3    Onyilagha, C.4    Uzonna, J.E.5
  • 36
    • 0034682553 scopus 로고    scopus 로고
    • The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge
    • Stobie, L., S. Gurunathan, C. Prussin, D. L. Sacks, N. Glaichenhaus, C. Y. Wu, and R. A. Seder. 2000. The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge. Proc. Natl. Acad. Sci. USA 97: 8427-8432.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8427-8432
    • Stobie, L.1    Gurunathan, S.2    Prussin, C.3    Sacks, D.L.4    Glaichenhaus, N.5    Wu, C.Y.6    Seder, R.A.7
  • 37
    • 0036604064 scopus 로고    scopus 로고
    • The role of IL-12 in maintaining resistance to Leishmania major
    • Park, A. Y., B. Hondowicz, M. Kopf, and P. Scott. 2002. The role of IL-12 in maintaining resistance to Leishmania major. J. Immunol. 168: 5771-5777.
    • (2002) J. Immunol. , vol.168 , pp. 5771-5777
    • Park, A.Y.1    Hondowicz, B.2    Kopf, M.3    Scott, P.4
  • 38
    • 0034661678 scopus 로고    scopus 로고
    • IL-12 is required to maintain a Th1 response during Leishmania major infection
    • Park, A. Y., B. D. Hondowicz, and P. Scott. 2000. IL-12 is required to maintain a Th1 response during Leishmania major infection. J. Immunol. 165: 896-902.
    • (2000) J. Immunol. , vol.165 , pp. 896-902
    • Park, A.Y.1    Hondowicz, B.D.2    Scott, P.3
  • 40
    • 0037373311 scopus 로고    scopus 로고
    • CD40-CD40 ligand costimulation is not required for initiation and maintenance of a Th1-type response to Leishmania major infection
    • Padigel, U. M., and J. P. Farrell. 2003. CD40-CD40 ligand costimulation is not required for initiation and maintenance of a Th1-type response to Leishmania major infection. Infect. Immun. 71: 1389-1395.
    • (2003) Infect. Immun. , vol.71 , pp. 1389-1395
    • Padigel, U.M.1    Farrell, J.P.2
  • 41
    • 0242494345 scopus 로고    scopus 로고
    • TRANCE-RANK costimulation is required for IL-12 production and the initiation of a Th1-type response to Leishmania major infection in CD40L-deficient mice
    • Padigel, U. M., N. Kim, Y. Choi, and J. P. Farrell. 2003. TRANCE-RANK costimulation is required for IL-12 production and the initiation of a Th1-type response to Leishmania major infection in CD40L-deficient mice. J. Immunol. 171: 5437-5441.
    • (2003) J. Immunol. , vol.171 , pp. 5437-5441
    • Padigel, U.M.1    Kim, N.2    Choi, Y.3    Farrell, J.P.4
  • 42
    • 20444413440 scopus 로고    scopus 로고
    • The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease
    • Wang, J., R. A. Anders, Y. Wang, J. R. Turner, C. Abraham, K. Pfeffer, and Y. X. Fu. 2005. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. J. Immunol. 174: 8173-8182.
    • (2005) J. Immunol. , vol.174 , pp. 8173-8182
    • Wang, J.1    Anders, R.A.2    Wang, Y.3    Turner, J.R.4    Abraham, C.5    Pfeffer, K.6    Fu, Y.X.7
  • 45
    • 0037124334 scopus 로고    scopus 로고
    • Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis
    • Scheu, S., J. Alferink, T. Pö tzel, W. Barchet, U. Kalinke, and K. Pfeffer. 2002. Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis. J. Exp. Med. 195: 1613-1624.
    • (2002) J. Exp. Med. , vol.195 , pp. 1613-1624
    • Scheu, S.1    Alferink, J.2    Pö Tzel, T.3    Barchet, W.4    Kalinke, U.5    Pfeffer, K.6
  • 46
    • 0242643722 scopus 로고    scopus 로고
    • LIGHT, a new TNF superfamily member, is essential for memory T helper cell-mediated activation of dendritic cells
    • Morel, Y., A. Truneh, R. T. Costello, and D. Olive. 2003. LIGHT, a new TNF superfamily member, is essential for memory T helper cell-mediated activation of dendritic cells. Eur. J. Immunol. 33: 3213-3219.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 3213-3219
    • Morel, Y.1    Truneh, A.2    Costello, R.T.3    Olive, D.4
  • 47
    • 0035451607 scopus 로고    scopus 로고
    • The TNF superfamily members LIGHT and CD154 (CD40 ligand) costimulate induction of dendritic cell maturation and elicit specific CTL activity
    • Morel, Y., A. Truneh, R. W. Sweet, D. Olive, and R. T. Costello. 2001. The TNF superfamily members LIGHT and CD154 (CD40 ligand) costimulate induction of dendritic cell maturation and elicit specific CTL activity. J. Immunol. 167: 2479-2486.
    • (2001) J. Immunol. , vol.167 , pp. 2479-2486
    • Morel, Y.1    Truneh, A.2    Sweet, R.W.3    Olive, D.4    Costello, R.T.5
  • 49
    • 0029076809 scopus 로고
    • Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice
    • Heinzel, F. P., R. M. Rerko, F. Ahmed, and E. Pearlman. 1995. Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice. J. Immunol. 155: 730-739.
    • (1995) J. Immunol. , vol.155 , pp. 730-739
    • Heinzel, F.P.1    Rerko, R.M.2    Ahmed, F.3    Pearlman, E.4
  • 51
    • 0037022865 scopus 로고    scopus 로고
    • T memory cells: Quality not quantity
    • Sprent, J. 2002. T memory cells: quality not quantity. Curr. Biol. 12: R174-R176.
    • (2002) Curr. Biol. , vol.12 , pp. R174-R176
    • Sprent, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.