The TNF superfamily members LIGHT and CD154 (CD40 ligand) costimulate induction of dendritic cell maturation and elicit specific CTL activity

Journal of Immunology

Volumn 167, Issue 5, 2001, Pages 2479-2486

  Morel, Y ^a   Truneh, A ^a   Sweet, R W ^a   Olive, D ^a   Costello, R T ^a  

^a INSTITUT PAOLI CALMETTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLYCOPROTEIN GP 39; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTATION; ARTICLE; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOTHERAPY; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

EID: 0035451607     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.5.2479     Document Type: Article

References (36)

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4. Help for cytotoxic-T-cell responses is mediated by CD40 signaling
5. + T cells requires CD154 expression by Th cells in acute graft versus host disease
6. LIGHT, a new member of the TNF superfamily, and lymphotoxin a are ligands for herpesvirus entry mediator
7. Reciprocal expression of the TNF family receptor HVEM and its ligand LIGHT on activated T cells: LIGHT down-regulates its own receptor
8. LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response
9. LIGHT, a novel ligand for lymphotoxin β receptor and TR2/HVEM, induces apoptosis and suppresses in vivo tumor formation via gene transfer
10. A newly identified member of tumor necrosis factor receptor super-family (TR6) suppresses LIGHT-mediated apoptosis
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16. Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth
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