LIGHT, a new member of the TNF superfamily, and lymphotoxin α are ligands for herpesvirus entry mediator

Immunity

Volumn 8, Issue 1, 1998, Pages 21-30

  Mauri, Davide N ^a   Ebner, Reinhard ^e   Montgomery, Rebecca I ^b   Kochel, Kristine D ^a   Cheung, Timothy C ^a   Yu, Guo Liang ^e   Ruben, Steve ^e   Murphy, Marianne ^d   Eisenberg, Roselyn J ^e   Cohen, Gary H ^c   Spear, Patricia G ^b   Ware, Carl F ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d GLAXOSMITHKLINE   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOTOXIN; TUMOR NECROSIS FACTOR; VIRUS ENVELOPE PROTEIN;

ARTICLE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; T LYMPHOCYTE ACTIVATION; VIRUS DNA CELL DNA INTERACTION; VIRUS INFECTIVITY;

EID: 0031907988     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80455-0     Document Type: Article

References (65)

1. Alimzhanov, M.B., Kuprash, D.V., Kosco-Vilbois, M.H., Luz, A., Turetskaya, R.L., Tarakhovsky, A., Rajewsky, K., Nedospasov, S.A., and Pfeffer, K. (1997). Abnormal development of secondary lymphoid tissues in lymphotoxin-β-deficient mice. Proc. Natl. Acad. Sci. USA 94, 9302-9307.
2. Androlewicz, M.J., Browning, J.L., and Ware, C.F. (1992). Lymphotoxin is expressed as a heteromeric complex with a distinct 33-kDa glycoprotein on the surface of an activated human T cell hybridoma. J. Biol. Chem. 267, 2542-2547.
3. Banks, T.A., Rouse, B.T., Kerley, M.K., Blair, P.J., Godfrey, V.L., Kuklin, N.A., Bouley, D.M., Thomas, J., Kanangat, S., and Mucenski, M.L. (1995). Lymphotoxin-alpha-deficient mice: effects on secondary lymphoid organ development and humoral immune responsiveness. J. Immunol. 155, 1685-1693.
4. Banner, D.W., D'Arcy, A., Janes, W., Gentz, R., Schoenfeld, H.J., Broger, C., Loetscher, H., and Lesslauer,W. (1993). Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell 73, 431-445.
5. Bertin, J., Armstrong, R.C., Ottilie, S., Martin, D.A., Wang, Y., Banks, S., Wang, G.-H., Senkevich, T.G., Alnemri, E.S., Moss, B., et al. (1997). Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1 -induced apoptosis. Proc. Natl. Acad. Sci. USA 94, 1172-1176.
6. Black, R.A., Rauch, CT., Kozlosky, C.J., Peschon, J.J., Slack, J.L., Wolfson, M.F., Castner, B.J., Stocking, K.L., Reddy, P., Srinivasan, S., et al. (1997). A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells. Nature 385, 729-733.
7. Browning, J., and Ribolini, A. (1989). Studies on the differing effects of tumor necrosis factor and lymphotoxin on the growth of several human tumor lines. J. Immunol. 143, 1859-1867.
8. Browning, J.L., Androlewicz, M.J., and Ware, C.F. (1991). Lymphotoxin and an associated 33-kDa glycoprotein are expressed on the surface of an activated human T cell hybridoma. J. Immunol. 147, 1230-1237.
9. Browning, J.L., Ngam-ek, A., Lawton, P., DeMarinis, J., Tizard, R., Chow, E.P., Hession, C., O'Brine-Greco, B., Foley, S.F., and Ware, C.F. (1993). Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface. Cell 72, 847-856.
10. Browning, J.L., Dougas, I., Ngam-ek, A., Bourdon, P.R., Ehrenfels, B.N., Miatkowski, K., Zafari, M., Yampaglia, A.M., Lawton, P., and Meier, W. (1995). Characterization of surface lymphotoxin forms: use of specific monoclonal antibodies and soluble receptors. J. Immunol. 154, 33-46.
11. Browning, J.L., Miatkowski, K., Griffiths, D.A., Bourdon, P.R., Hession, C., Ambrose, C.M., and Meier, W. (1996). Preparation and characterization of soluble recombinant heterotrimeric complexes of human lymphotoxins alpha and beta. J. Biol. Chem. 271, 8618-8626.
12. Brunner, T., Mogil, R.J., LaFace, D., Yoo, N.J., Mahboubi, A., Echeverri, F., Martin, S.J., Force, W.R., Lynch, D.H., and Ware, C.F. (1995). Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373, 441-444.
13. Campadelli-Fiume, G., Arsenakis, M., Farabegoli, F., and Roizman, B. (1988). Entry of herpes simplex virus 1 in BJ cells that constitutively expressviral glycoprotein D is by endocytosis and results in degradation of the virus. J. Virol. 62, 159-167.
14. Cohen, G.H., Wilcox, W.C., Sodora, D.L., Long, D. Levin, J.Z., and Eisenberg, R.J. (1988). Expression of herpes simplex virus type 1 glycoprotein D deletion mutants in mammalian cells. J. Virol. 62, 1932-1940.
15. Crowe, P.D., VanArsdale, T.L., Walter, B.N., Dahms, K.M., and Ware, C.F. (1994a). Production of lymphotoxin (LT alpha) and a soluble dimeric form of its receptor using the baculovirus expression system. J. Immunol. Meth. 168, 79-89.
16. Crowe, P.D., VanArsdale, T.L., Walter, B.N., Ware, C.F., Hession, C., Ehrenfels, B., Browning, J.L., Din, W.S., Goodwin, R.G., and Smith, C.A. (1994b). A lymphotoxin-beta-specific receptor. Science 264, 707-710.
17. Degli-Esposti, M.A., Davis-Smith, T., Din, W.S., Smolak, P., Goodwin, R.G., and Smith, C.A. (1997). Activation of the lymphotoxin b receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells. J. Immunol. 158, 1756-1762.
18. De Togni, P., Goellner, J., Ruddle, N.H., Streeter, P.R., Fick, A., Mariathasan, S., Smith, S.C., Carlson, R., Shornick, L.P., Strauss-Schoenberger, J., et al. (1994). Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264, 703-706.
19. Eck, M.J., and Sprang, S.R. (1989). The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding. J. Biol. Chem. 264, 17595-17605.
20. Eck, M.J., Ultsch, M., Rinderknecht, E., de Vos, A.M., and Sprang, S.R. (1992). The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution. J. Biol. Chem. 267, 2119-2122.
21. Ettinger, R., Browning, J.L., Michie, S.A., van Ewijk, W., and McDevitt, H.O. (1996). Disrupted splenic architecture, but normal lymphnode development in mice expressing a soluble lymphotoxin-β receptor-IgG1 chimeric fusion protein. Proc. Natl. Acad. Sci. USA 93, 13102-13107.
22. Force, W.R., Walter, B.N., Hession, C., Tizard, R., Kozak, C.A., Browning, J.L., and Ware, C.F. (1996). Mouse lymphotoxin-β receptor. Molecular genetics, ligand binding, and expression. J. Immunol. 155, 5280-5288.
23. Fu, Y.-X., Molina, H., Matsumoto, M., Huang, G., Min, J., and Chaplin, D.D. (1997). Lymphotoxin-α (LTα) supports development of splenic follicular structure that is required for IgG responses. J. Exp. Med. 185, 2111-2120.
24. Goh, C.R., Loh, C.S., and Porter, A.G. (1991). Aspartic acid 50 and tyrosine 108 are essential for receptor binding and cytotoxic activity of tumour necrosis factor beta (lymphotoxin). Protein Eng. 4, 785-791.
25. Gooding, L.R. (1992). Virus proteins that counteract host immune defenses. Cell 71, 5-7.
26. Gray, P., Aggarwal, B., Benton, C., Bringman, T., Henzel, W., Jarrett, J., Leung, D., Moffat, B., Ng, P., Svedersky, L., et al. (1984). Cloning and expression of the cDNA for human lymphotoxin: a lymphokine with tumor necrosis activity. Nature 372, 721-724.
27. Hochman, P.S., Majeau, G.R., Mackay, F., and Browning, J.L. (1996). Proinflammatory responses are efficiently induced by homotrimeric but not heterotrimeric lymphotoxin ligands. J. Inflammation 46, 220-234.
28. Hsu, H., Solovyev, I., Colobero, A., Elliott, R., Kelley, M., and Boyle, W.J. (1997). ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5. J. Biol. Chem. 272, 13471-13474.
29. Johnson, R.M., and Spear, P.G. (1989). Herpes simplex virus glycoprotein D mediates interference with herpes simplex virus infection. J. Virol. 63, 818-827.
30. Jones, E.Y., Stuart, D.I., and Walker, N.P. (1989). Structure of tumour necrosis factor. Nature 338, 225-228.
31. -i-) mutant mice. J. Exp. Med. 185, 2157-2170.
32. Koni, P.A., Sacca, R., Lawton, P., Browning, J.L., Ruddle, N.H., and Flavell, R.A. (1997). Distinct roles in lymphoid organogenesis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice. Immunity 6, 491-500.
33. Kratz, A., Campos-Neto, A., Hanson, M.S., and Ruddle, N.H. (1996). Chronic inflammation caused by lymphotoxin is lymphoid neogenesis. J. Exp. Med. 183, 1461-1472.
34. Kwon, B.S., Tan, K.B., Ni, J., Oh-OK-Kwi, Lee, Z.H., Kim, K.K., Kim, Y-J., Wang, S., Gentz, R., Yu, G-L., et al. (1997). A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. J. Biol. Chem. 272, 14272-14276.
35. Lawton, P., Nelson, J., Tizard, R., and Browning, J.L. (1995). Characterization of themouse lymphotoxin-beta gene. J. Immunol. 154, 239-246.
36. Loetscher, H., Pan, Y., Lahm, H., Gentz, R., Brockhaus, M., Tabuchi, H., and Lesslauer, W. (1990). Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor. Cell 61, 351-359.
37. Mariathasan, S., Matsumoto, M., Baranyay, F., Nahm, M.H., Kanagawa, O., and Chaplin, D.D. (1995). Absence of lymph nodes in lymphotoxin-α(LT-α)-deficient mice is due to abnormal organ development, not defective lymphocyte migration. J. Inflammation 45, 72-78.
38. Marsters, S.A., Ayres, T.M., Skuatch, M., Gray, C.L., Rothe, M.L., and Ashkenazi, A. (1997). Herpesvirus entry mediator, a member of the tumor necrosis factor receptor family (TNFR), interacts with members of the TNFR-associated factor family and activates the transcription factors NF-κB and AP-1. J. Biol. Chem. 272, 14029-14032.
39. Matsumoto, M., Lo, S.F., Carruthers, C.J.L., Min, J., Mariathasan, S., Huang, G., Plas, D.R., Martin, S.M., Geha, R.S., Nahm, M.H., and Chaplin, D.D. (1996a). Affinity maturation without germinal centers in lymphotoxin-α-deficient mice. Nature 382, 462-466.
40. Matsumoto, M., Mariathasan, S., Nahm, M.H., Baranyay, F., Preschon, J.J., and Chaplin, D.D. (1996b). Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers. Science 271, 1289-1291.
41. Matsumoto, M., Hsieh, T.-Y., Zhu, N., VanArsdale, T., Hwang, S.B., Jeng, K.-S., Gorbalenya, A.E., Lo, S.-Y., Ou, J.-H., Ware, C.F., and Lai, M.M.C. (1997a). Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-β receptor. Proc. Natl. Acad. Sci. USA 71, 1301-1309.
42. Matsumoto, M., Fu, X.-Y., Molina, H., amd Chaplin, D.D. (1997b). Lymphotoxin-alpha-deficient and TNF-receptor-l-deficient mice define developmental and functional characteristics of germinal centers. Immunol. Rev. 156, 137-144.
43. Montgomery, R.I., Warner, M.S., Lum, B., and Spear, P.G. (1996). Herpes simplex virus 1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Cell 87, 427-436.
44. Mosialos, G., Birkenbach, M., Yalamanchili, R., VanArsdale, T., Ware, C., and Kieff, E. (1995). The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell 80, 389-399.
45. Murphy, M., Walter, B.N., Pike-Nobile, L., Fanger, N.A., Guyre, P.M., Browning, J.L., Ware, C.F., and Epstein, L.B. (1998). Expression of the lymphotoxin-β receptor on follicular stromal cells in human lymphoid tissues. Cell Death Differ., in press.
46. Nakano, H., Oshima, H., Chung, W., Williams-Abbott, L., Ware, C., Yagita, H., and Okumura, K. (1996). TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin-β receptor. J. Biol. Chem. 271, 14661-14664.
47. Nicola, A.V., Willis, S.H., Naidoo, R.J., Eisenberg, R.J., and Cohen, G.H. (1996). Structure-function analysis of soluble forms of herpes simplex virus glycoprotein D. J. Virology 6, 3815-3822.
48. Pasparakis, M., Alexopoulou, L., Grell, M., Pfizenmaier, K., Bluethmann, H., and Kollias, G. (1997). Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor. Proc. Natl. Acad. Sci. USA 94, 6319-6323.
49. Pennica, D., Nedwin, G.E., Hayflick, J.S., Seeburg, P.H., Derynck, R., Palladino, M.A., Kohr, W.J., Aggarwal, B.B., and Goeddel, D.V. (1984). Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 312, 724-729.
50. Picarella, D.E., Kratz, A., Li, C.B., Ruddle, N.H., and Flavell, R.A. (1992). Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas. Proc. Natl. Acad. Sci. USA 89, 10036-10040.
51. Pinckard, J.K., Sheehan, K.C.F., and Schreiber, R.D. (1997). Ligand-induced formation of p55 and p75 tumor necrosis factor receptor heterocomplexes on intact cells. J. Biol. Chem. 272, 10784-10789.
52. Rennert, P.D., Browning, J.L., Mebius, R., Mackay, F., and Hochman, P.S. (1996). Surface lymphotoxin αβ complex is required for the development of peripheral lymphoid organs. J. Exp. Med. 184, 1999-2006.
53. Schall, T.J., Lewis, M., Koller, K.J., Lee, A., Rice, G.G., Wong, G.H., Gatanaga, T., Granger, G.A., Lentz, R., Raab, H., et al. (1990). Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61, 361-370.
54. Schreiber, M., Sedger, L., and McFadden, G. (1997). Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition. J. Virol. 71, 2171-2181.
55. Shisler, J., Yang, C., Walter, B.N., Ware, C.F., and Gooding, L.R. (1997). The adenovirus E3-10.4K/14.5K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis. J. Virology 71, 8299-8306.
56. Smith, C.A., Davis, T., Anderson, D., Solam, L., Beckmann, M.P., Jerzy, R., Dower, S. K., Cosman, D., and Goodwin, R.G. (1990). A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 248, 1019-1023.
57. Smith, C.A., Farrah, T., and Goodwin, R.G. (1994). The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76, 959-962.
58. Spear, P.G. (1993). Entry of alphaherpesviruses into cells. Semin. Virol. 4, 167-180.
59. Tracey, K.J., and Cerami, A. (1994). Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu. Rev. Med. 45, 491-503.
60. VanArsdale, T.L., VanArsdale, S.L., Force, W.R., Walter, B.N., Mosialos, G., Kieff, E., Reed, J.C., and Ware, C.F. (1997). Lymphotoxin-β receptor signaling complex: role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB. Proc. Natl. Acad. Sci. USA 94, 2460-2465.
61. Ware, C.F., Green, L.M., Reade, J., Stern, M.L., and Berger, A.E. (1986). Human T cell hybridomas producing cytotoxic lymphokines: induction of lymphotoxin release and killer cell activity by anti-CD3 monoclonal antibody or lectins and phorbol ester. Lymphokine Res. 5, 313-324.
62. Ware, C.F., Crowe, P.D., Grayson, M.H., Androlewicz, M.J., and Browning, J.L. (1992). Expression of surface lymphotoxin and tumor necrosis factoron activated T, B, and natural killer cells. J. Immunol. 149, 3881-3888.
63. Ware, C.F., VanArsdale, T.L., Crowe, P.D., and Browning, J.L. (1995). The ligands and receptors of the lymphotoxin system. In Pathways for Cytolysis. G. M. Griffiths and J. Tschopp, eds. (Basel, Switzerland: Springer-Verlag), pp. 175-218.
64. Whitbeck, J.C., Peng, C., Lou, H., Xu, R., Willis, S.H., Ponce de Leon, M., Peng, T., Nicola, A.V., Montgomery, R.I., Warner, M.S., et al. (1997). Glycoprotein D of herpes simplex virus binds directly to HVEM, a mediator of HSV entry. J. Virol. 71, 6083-6093.
65. Williams-Abbott, L., Walter, B.N., Cheung, T., Goh, C.R., Porter, A.G., and Ware, C.F. (1997). The lymphotoxin-α (LTα) subunit is essential for the assembly, but not receptor specificity, of the membrane-anchored LTα1β2 heterotrimeric ligand. J. Biol. Chem. 72, 19451-19456.