The prognostic significance of bromodomain PHD-finger transcription factor in colorectal carcinoma and association with vimentin and E-cadherin

Journal of Cancer Research and Clinical Oncology

Volumn 141, Issue 8, 2015, Pages 1465-1474

  Xiao, Shuai ^a   Liu, Longfei ^a   Lu, Xianzhou ^a   Long, Jianwu ^a   Zhou, Xiaojun ^a   Fang, Min ^a  

^a Affiliated Nanhua Hospital of Nanhua University   (China)

Author keywords

Bromodomain PHD finger transcription factor; Colorectal cancer; E cadherin; Epithelial mesenchymal transition; Prognosis; Vimentin

Indexed keywords

BROMODOMAIN PHD FINGER TRANSCRIPTION FACTOR; MESSENGER RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; ANTIGENS, NUCLEAR; CADHERINS; FETAL ALZHEIMER ANTIGEN; NERVE TISSUE PROTEINS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

ADULT; ARTICLE; CANCER PROGNOSIS; CANCER TISSUE; COLORECTAL CARCINOMA; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; EPITHELIAL-MESENCHYMAL TRANSITION; GENETICS; HUMANS; METABOLISM; PATHOLOGY; PROGNOSIS; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, NUCLEAR; CADHERINS; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; PROGNOSIS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL; VIMENTIN; YOUNG ADULT;

EID: 84931568503     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-015-1937-y     Document Type: Article

References (26)

1. Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA (2009) Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest 119:1438–1449
2. Alderton GK (2013) Metastasis: epithelial to mesenchymal and back again. Nat Rev Cancer 13:3
3. Bastid J (2012) EMT in carcinoma progression and dissemination: facts, unanswered questions, and clinical considerations. Cancer Metastasis Rev 31:277–283
4. Brenner H, Kloor M, Pox CP (2014) Colorectal cancer. Lancet 383:1490-1502
5. Buganim Y, Goldstein I, Lipson D, Milyavsky M, Polak-Charcon S, Mardoukh C, Solomon H, Kalo E, Madar S, Brosh R, Perelman M, Navon R, Goldfinger N, Barshack I, Yakhini Z, Rotter V (2010) A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype. PLoS One 5:e9657
6. Carvajal-Vergara X, Sevilla A, D’Souza SL, Ang YS, Schaniel C, Lee DF, Yang L, Kaplan AD, Adler ED, Rozov R, Ge Y, Cohen N, Edelmann LJ, Chang B, Waghray A, Su J, Pardo S, Lichtenbelt KD, Tartaglia M, Gelb BD, Lemischka IR (2010) Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 465:808–812
7. Craene BD, Berx G (2012) Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13:97–110
8. Fan CC, Wang TY, Cheng YA, Jiang SS, Cheng CW, Lee AY, Kao TY (2013) Expression of E-cadherin, Twist, and p53 and their prognostic value in patients with oral squamous cell carcinoma. J Cancer Res Clin Oncol 139:1735–1744
9. Goller T, Vauti F, Ramasamy S, Arnold HH (2008) Transcriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse development. Mol Cell Biol 28:6819–6827
10. Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674
11. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69–90
12. Jones MH, Hamana N, Shimane M (2000) Identification and characterization of BPTF, a novel bromodomain transcription factor. Genomics 63:35–39
13. Kalluri R (2009) EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest 119:1417–1419
14. Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420–1428
15. Kim K, Punj V, Choi J, Heo K, Kim JM, Laird PW, An W (2013) Gene dysregulation by histone variant in bladder cancer. Epigenet Chromatin 6:34
16. Lamouille S, Xu J, Derynck R (2014) Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15:178–196
17. Landry J, Sharov AA, Piao Y, Sharova LV, Xiao H, Southon E, Matta J, Tessarollo L, Zhang YE, Ko MS, Kuehn MR, Yamaguchi TP, Wu C (2008) Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. PLoS Genet 4:e1000241
18. Lim J, Thiery JP (2012) Epithelial-mesenchymal transitions: insights from development. Development 139:3471–3486
19. Malouf GG, Taube JH, Lu Y, Roysarkar T, Panjarian S, Estecio MR, Jelinek J, Yamazaki J, Raynal NJ, Long H, Tahara T, Tinnirello A, Ramachandran P, Zhang XY, Liang S, Mani SA, Issa JP (2013) Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition. Genome Biol 14:R144
20. Mulder KW, Wang X, Escriu C, Ito Y, Schwarz RF, Gillis J, Sirokmany G, Donati G, Uribe-Lewis S, Pavlidis P, Murrell A, Markowetz F, Watt FM (2012) Diverse epigenetic strategies interact to control epidermal differentiation. Nat Cell Biol 14:753–763
21. Sanchez-Tillo E, Liu Y, de Barrios O, Siles L, Fanlo L, Cuatrecasas M, Darling DS, Dean DC, Castells A, Postigo A (2012) EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness. Cell Mol Life Sci 69:3429–3456
22. Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139:871–890
23. Wang Y, Wen M, Kwon Y, Xu Y, Liu Y, Zhang P, He X, Wang Q, Huang Y, Jen KY, Labarge MA, You L, Kogan SC, Gray JW, Mao JH, Wei G (2014) CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. Cancer Res 74(2):520-531
24. Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD (2006) A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 442:86–90
25. Xiao S, Liu L, Fang M, Zhou X, Peng X, Long J, Lu X (2014) BPTF associated with EMT indicates negative prognosis in patients with hepatocellular carcinoma. Dig Dis Sci. doi:10.1007/s10620-014-3411-0
26. Yang J, Weinberg RA (2008) Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 14:818–829