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Volumn 137, Issue 4, 2015, Pages 797-809

Interaction between bone marrow stromal cells and neuroblastoma cells leads to a VEGFA-mediated osteoblastogenesis

Author keywords

mesenchymal cells; neuroblastoma; osteoblastogenesis; VEGFA

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN A; CORE BINDING FACTOR ALPHA 1 SUBUNIT; RNA, MESSENGER; RUNX2 PROTEIN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VEGFA PROTEIN, HUMAN;

EID: 84931564299     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29465     Document Type: Article
Times cited : (12)

References (44)
  • 1
    • 4644261592 scopus 로고    scopus 로고
    • Mechanisms of bone metastasis
    • PubMed PMID: 15084698
    • Roodman GD,. Mechanisms of bone metastasis. N Engl J Med 2004; 350: 1655-64. doi: 10.1056/NEJMra030831. PubMed PMID: 15084698.
    • (2004) N Engl J Med , vol.350 , pp. 1655-1664
    • Roodman, G.D.1
  • 2
    • 79957484310 scopus 로고    scopus 로고
    • Cancer to bone: A fatal attraction
    • PubMed PMID: 21593787; PubMed Central PMCID: PMC3666847
    • Weilbaecher KN, Guise TA, McCauley LK,. Cancer to bone: a fatal attraction. Nat Rev Cancer 2011; 11: 411-25. doi: 10.1038/nrc3055. PubMed PMID: 21593787; PubMed Central PMCID: PMC3666847.
    • (2011) Nat Rev Cancer , vol.11 , pp. 411-425
    • Weilbaecher, K.N.1    Guise, T.A.2    McCauley, L.K.3
  • 3
    • 0032455216 scopus 로고    scopus 로고
    • Cancer and bone
    • PubMed PMID: 9494779
    • Guise TA, Mundy GR,. Cancer and bone. Endocr Rev 1998; 19: 18-54. doi: 10.1210/edrv.19.1.0323. PubMed PMID: 9494779.
    • (1998) Endocr Rev , vol.19 , pp. 18-54
    • Guise, T.A.1    Mundy, G.R.2
  • 4
    • 23944432868 scopus 로고    scopus 로고
    • Mechanisms of bone invasion and metastasis in human neuroblastoma
    • PubMed PMID: 15975706
    • Sohara Y, Shimada H, DeClerck YA,. Mechanisms of bone invasion and metastasis in human neuroblastoma. Cancer Lett 2005; 228: 203-9. doi: 10.1016/j.canlet.2005.01.059. PubMed PMID: 15975706.
    • (2005) Cancer Lett , vol.228 , pp. 203-209
    • Sohara, Y.1    Shimada, H.2    Declerck, Y.A.3
  • 5
    • 0035425227 scopus 로고    scopus 로고
    • Biology of osteoclast activation in cancer
    • PubMed PMID: 11481364
    • Roodman GD,. Biology of osteoclast activation in cancer. J Clin Oncol 2001; 19: 3562-71. PubMed PMID: 11481364.
    • (2001) J Clin Oncol , vol.19 , pp. 3562-3571
    • Roodman, G.D.1
  • 6
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    • PubMed PMID: 20703299; PubMed Central PMCID: PMC3146551
    • Mendez-Ferrer S, Michurina TV, Ferraro F, et al., Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 2010; 466: 829-34. doi: 10.1038/nature09262. PubMed PMID: 20703299; PubMed Central PMCID: PMC3146551.
    • (2010) Nature , vol.466 , pp. 829-834
    • Mendez-Ferrer, S.1    Michurina, T.V.2    Ferraro, F.3
  • 7
    • 33846150682 scopus 로고    scopus 로고
    • The role of wnts in bone metastases
    • PubMed PMID: 17160558
    • Hall CL, Keller ET,. The role of wnts in bone metastases. Cancer Metastasis Rev 2006; 25: 551-8. doi: 10.1007/s10555-006-9022-2. PubMed PMID: 17160558.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 551-558
    • Hall, C.L.1    Keller, E.T.2
  • 8
    • 79751472667 scopus 로고    scopus 로고
    • Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
    • PubMed PMID: 21295524; PubMed Central PMCID: PMC3040415
    • Sethi N, Dai X, Winter CG, et al., Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell 2011; 19: 192-205. doi: 10.1016/j.ccr.2010.12.022. PubMed PMID: 21295524; PubMed Central PMCID: PMC3040415.
    • (2011) Cancer Cell , vol.19 , pp. 192-205
    • Sethi, N.1    Dai, X.2    Winter, C.G.3
  • 9
    • 0027409133 scopus 로고
    • Modulation of expression and cell surface binding of members of the transforming growth factor-beta superfamily during retinoic acid-induced osteoblastic differentiation of multipotential mesenchymal cells
    • PubMed PMID: 8385738
    • Gazit D, Ebner R, Kahn AJ, et al., Modulation of expression and cell surface binding of members of the transforming growth factor-beta superfamily during retinoic acid-induced osteoblastic differentiation of multipotential mesenchymal cells. Mol Endocrinol 1993; 7: 189-98. doi: 10.1210/mend.7.2.8385738. PubMed PMID: 8385738.
    • (1993) Mol Endocrinol , vol.7 , pp. 189-198
    • Gazit, D.1    Ebner, R.2    Kahn, A.J.3
  • 10
    • 33645351946 scopus 로고    scopus 로고
    • BMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype
    • PubMed PMID: 16598384; PubMed Central PMCID: PMC2435171
    • Phimphilai M, Zhao Z, Boules H, et al., BMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype. J Bone Miner Res 2006; 21: 637-46. doi: 10.1359/jbmr.060109. PubMed PMID: 16598384; PubMed Central PMCID: PMC2435171.
    • (2006) J Bone Miner Res , vol.21 , pp. 637-646
    • Phimphilai, M.1    Zhao, Z.2    Boules, H.3
  • 11
    • 34250683435 scopus 로고    scopus 로고
    • Neuroblastoma
    • PubMed PMID: 17586306
    • Maris JM, Hogarty MD, Bagatell R, et al., Neuroblastoma. Lancet 2007; 369: 2106-20. doi: 10.1016/S0140-6736(07)60983-0. PubMed PMID: 17586306.
    • (2007) Lancet , vol.369 , pp. 2106-2120
    • Maris, J.M.1    Hogarty, M.D.2    Bagatell, R.3
  • 12
    • 84878251843 scopus 로고    scopus 로고
    • Neuroblastoma: Developmental biology, cancer genomics and immunotherapy
    • PubMed PMID: 23702928
    • Cheung NK, Dyer MA,. Neuroblastoma: developmental biology, cancer genomics and immunotherapy. Nat Rev Cancer 2013; 13: 397-411. doi: 10.1038/nrc3526. PubMed PMID: 23702928.
    • (2013) Nat Rev Cancer , vol.13 , pp. 397-411
    • Cheung, N.K.1    Dyer, M.A.2
  • 13
    • 4143057125 scopus 로고    scopus 로고
    • In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells
    • PubMed PMID: 15300794
    • Granchi D, Amato I, Battistelli L, et al., In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells. Int J Cancer 2004; 111: 829-38. doi: 10.1002/ijc.20308. PubMed PMID: 15300794.
    • (2004) Int J Cancer , vol.111 , pp. 829-838
    • Granchi, D.1    Amato, I.2    Battistelli, L.3
  • 14
    • 0035866399 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor kappaB ligand (RANKL) is a key molecule of osteoclast formation for bone metastasis in a newly developed model of human neuroblastoma
    • PubMed PMID: 11245477
    • Michigami T, Ihara-Watanabe M, Yamazaki M, et al., Receptor activator of nuclear factor kappaB ligand (RANKL) is a key molecule of osteoclast formation for bone metastasis in a newly developed model of human neuroblastoma. Cancer Res 2001; 61: 1637-44. PubMed PMID: 11245477.
    • (2001) Cancer Res , vol.61 , pp. 1637-1644
    • Michigami, T.1    Ihara-Watanabe, M.2    Yamazaki, M.3
  • 15
    • 13944258987 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells
    • PubMed PMID: 15734993
    • Sohara Y, Shimada H, Minkin C, et al., Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells. Cancer Res 2005; 65: 1129-35. doi: 10.1158/0008-5472.CAN-04-2853. PubMed PMID: 15734993.
    • (2005) Cancer Res , vol.65 , pp. 1129-1135
    • Sohara, Y.1    Shimada, H.2    Minkin, C.3
  • 16
    • 84921307794 scopus 로고    scopus 로고
    • Bone Marrow-derived mesenchymal stromal cells promote survival and drug resistance in tumor cells
    • Bergfeld SA, Blavier L, Declerck YA,. Bone Marrow-derived mesenchymal stromal cells promote survival and drug resistance in tumor cells. Mol Cancer Ther 2014; 13: 962-975.
    • (2014) Mol Cancer Ther , vol.13 , pp. 962-975
    • Bergfeld, S.A.1    Blavier, L.2    Declerck, Y.A.3
  • 17
    • 84861754133 scopus 로고    scopus 로고
    • Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells
    • PubMed PMID: 21881969
    • Baniwal SK, Shah PK, Shi Y, et al., Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells. Osteoporos Int 2012; 23: 1399-413. doi: 10.1007/s00198-011-1728-5. PubMed PMID: 21881969.
    • (2012) Osteoporos Int , vol.23 , pp. 1399-1413
    • Baniwal, S.K.1    Shah, P.K.2    Shi, Y.3
  • 18
    • 0038746619 scopus 로고    scopus 로고
    • Lytic bone lesions in human neuroblastoma xenograft involve osteoclast recruitment and are inhibited by bisphosphonate
    • PubMed PMID: 12810621
    • Sohara Y, Shimada H, Scadeng M, et al., Lytic bone lesions in human neuroblastoma xenograft involve osteoclast recruitment and are inhibited by bisphosphonate. Cancer Res 2003; 63: 3026-31. PubMed PMID: 12810621.
    • (2003) Cancer Res , vol.63 , pp. 3026-3031
    • Sohara, Y.1    Shimada, H.2    Scadeng, M.3
  • 19
    • 0034087691 scopus 로고    scopus 로고
    • Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
    • PubMed PMID: 10772661; PubMed Central PMCID: PMC517491
    • Klement G, Baruchel S, Rak J, et al., Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Investig 2000; 105: R15-24. doi: 10.1172/JCI8829. PubMed PMID: 10772661; PubMed Central PMCID: PMC517491.
    • (2000) J Clin Investig , vol.105 , pp. R15-R24
    • Klement, G.1    Baruchel, S.2    Rak, J.3
  • 20
    • 0034131079 scopus 로고    scopus 로고
    • 'Accidental' anti-angiogenic drugs. Anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples
    • PubMed PMID: 10882863
    • Kerbel RS, Viloria-Petit A, Klement G, et al., 'Accidental' anti-angiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples. Eur J Cancer 2000; 36: 1248-57. PubMed PMID: 10882863.
    • (2000) Eur J Cancer , vol.36 , pp. 1248-1257
    • Kerbel, R.S.1    Viloria-Petit, A.2    Klement, G.3
  • 21
    • 23844450576 scopus 로고    scopus 로고
    • A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma
    • PubMed PMID: 16103078
    • Das B, Yeger H, Tsuchida R, et al., A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma. Cancer Res 2005; 65: 7267-75. doi: 10.1158/0008-5472.CAN-04-4575. PubMed PMID: 16103078.
    • (2005) Cancer Res , vol.65 , pp. 7267-7275
    • Das, B.1    Yeger, H.2    Tsuchida, R.3
  • 22
    • 84862918101 scopus 로고    scopus 로고
    • Transcriptional regulation of vascular endothelial growth factor (VEGF) by osteoblast-specific transcription factor osterix (osx) in osteoblasts
    • PubMed PMID: 22110141; PubMed Central PMCID: PMC3265850
    • Tang W, Yang F, Li Y, et al., Transcriptional regulation of vascular endothelial growth factor (VEGF) by osteoblast-specific transcription factor osterix (osx) in osteoblasts. J Biol Chem 2012; 287: 1671-8. doi: 10.1074/jbc.M111.288472. PubMed PMID: 22110141; PubMed Central PMCID: PMC3265850.
    • (2012) J Biol Chem , vol.287 , pp. 1671-1678
    • Tang, W.1    Yang, F.2    Li, Y.3
  • 23
    • 84866001590 scopus 로고    scopus 로고
    • Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation
    • PubMed PMID: 22886301; PubMed Central PMCID: PMC3428080
    • Liu Y, Berendsen AD, Jia S, et al., Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation. J Clin Investig 2012; 122: 3101-13. doi: 10.1172/JCI61209. PubMed PMID: 22886301; PubMed Central PMCID: PMC3428080.
    • (2012) J Clin Investig , vol.122 , pp. 3101-3113
    • Liu, Y.1    Berendsen, A.D.2    Jia, S.3
  • 24
    • 58249095935 scopus 로고    scopus 로고
    • Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells
    • PubMed PMID: 19118018; PubMed Central PMCID: PMC2761219
    • Ara T, Song L, Shimada H, et al., Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res 2009; 69: 329-37. doi: 10.1158/0008-5472.CAN-08-0613. PubMed PMID: 19118018; PubMed Central PMCID: PMC2761219.
    • (2009) Cancer Res , vol.69 , pp. 329-337
    • Ara, T.1    Song, L.2    Shimada, H.3
  • 25
    • 0346363760 scopus 로고    scopus 로고
    • The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
    • PubMed PMID: 14695408
    • Tian E, Zhan F, Walker R, et al., The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 2003; 349: 2483-94. doi: 10.1056/NEJMoa030847. PubMed PMID: 14695408.
    • (2003) N Engl J Med , vol.349 , pp. 2483-2494
    • Tian, E.1    Zhan, F.2    Walker, R.3
  • 26
    • 0037301981 scopus 로고    scopus 로고
    • Mechanisms of osteolytic bone metastases in breast carcinoma
    • PubMed PMID: 12548583
    • Kakonen SM, Mundy GR,. Mechanisms of osteolytic bone metastases in breast carcinoma. Cancer 2003; 97 (3 Suppl): 834-9. doi: 10.1002/cncr.11132. PubMed PMID: 12548583.
    • (2003) Cancer , vol.97 , Issue.3 , pp. 834-839
    • Kakonen, S.M.1    Mundy, G.R.2
  • 27
    • 24744439747 scopus 로고    scopus 로고
    • Prostate cancer cells promote osteoblastic bone metastases through wnts
    • PubMed PMID: 16140917
    • Hall CL, Bafico A, Dai J, et al., Prostate cancer cells promote osteoblastic bone metastases through wnts. Cancer Res 2005; 65: 7554-60. doi: 10.1158/0008-5472.CAN-05-1317. PubMed PMID: 16140917.
    • (2005) Cancer Res , vol.65 , pp. 7554-7560
    • Hall, C.L.1    Bafico, A.2    Dai, J.3
  • 28
    • 24644482494 scopus 로고    scopus 로고
    • The BMP signaling and in vivo bone formation
    • PubMed PMID: 16125875; PubMed Central PMCID: PMC2667963
    • Cao X, Chen D,. The BMP signaling and in vivo bone formation. Gene 2005; 357: 1-8. doi: 10.1016/j.gene.2005.06.017. PubMed PMID: 16125875; PubMed Central PMCID: PMC2667963.
    • (2005) Gene , vol.357 , pp. 1-8
    • Cao, X.1    Chen, D.2
  • 29
    • 84858200481 scopus 로고    scopus 로고
    • Regulation of bone and cartilage development by network between BMP signalling and transcription factors
    • PubMed PMID: 22253449. [PMC][10.1093/jb/mvs004] [22253449]29
    • Nishimura R, Hata K, Matsubara T, et al., Regulation of bone and cartilage development by network between BMP signalling and transcription factors. J Biochem 2012; 151: 247-54. doi: 10.1093/jb/mvs004. PubMed PMID: 22253449. [PMC][10.1093/jb/mvs004] [22253449]29.
    • (2012) J Biochem , vol.151 , pp. 247-254
    • Nishimura, R.1    Hata, K.2    Matsubara, T.3
  • 30
    • 11144237716 scopus 로고    scopus 로고
    • Osteoblasts in prostate cancer metastasis to bone
    • PubMed PMID: 15630412
    • Logothetis CJ, Lin SH,. Osteoblasts in prostate cancer metastasis to bone. Nat Rev Cancer 2005; 5: 21-8. doi: 10.1038/nrc1528. PubMed PMID: 15630412.
    • (2005) Nat Rev Cancer , vol.5 , pp. 21-28
    • Logothetis, C.J.1    Lin, S.H.2
  • 31
    • 0037025352 scopus 로고    scopus 로고
    • Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via smad and mitogen-activated protein kinase signaling pathways
    • PubMed PMID: 11964407
    • Kakonen SM, Selander KS, Chirgwin JM, et al., Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via smad and mitogen-activated protein kinase signaling pathways. J Biol Chem 2002; 277: 24571-8. doi: 10.1074/jbc.M202561200. PubMed PMID: 11964407.
    • (2002) J Biol Chem , vol.277 , pp. 24571-24578
    • Kakonen, S.M.1    Selander, K.S.2    Chirgwin, J.M.3
  • 32
    • 0033050818 scopus 로고    scopus 로고
    • Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebo-controlled trial. Protocol 18 aredia breast cancer study group
    • PubMed PMID: 10071275
    • Theriault RL, Lipton A, Hortobagyi GN, et al., Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 aredia breast cancer study group. J Clin Oncol 1999; 17: 846-54. PubMed PMID: 10071275.
    • (1999) J Clin Oncol , vol.17 , pp. 846-854
    • Theriault, R.L.1    Lipton, A.2    Hortobagyi, G.N.3
  • 33
    • 84889247463 scopus 로고    scopus 로고
    • Zoledronic acid in the treatment of metastatic breast cancer
    • PubMed PMID: 24100278
    • Lluch A, Cueva J, Ruiz-Borrego M, et al., Zoledronic acid in the treatment of metastatic breast cancer. Anticancer Drugs 2014; 25: 1-7. doi: 10.1097/CAD.0000000000000020. PubMed PMID: 24100278.
    • (2014) Anticancer Drugs , vol.25 , pp. 1-7
    • Lluch, A.1    Cueva, J.2    Ruiz-Borrego, M.3
  • 34
    • 47249149740 scopus 로고    scopus 로고
    • Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
    • PubMed PMID: 18546262; PubMed Central PMCID: PMC3732167
    • Bu G, Lu W, Liu CC, Selander K, Yoneda T, Hall C, Keller ET, Li Y,. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases. Int J Cancer 2008; 123: 1034-42. doi: 10.1002/ijc.23625. PubMed PMID: 18546262; PubMed Central PMCID: PMC3732167.
    • (2008) Int J Cancer , vol.123 , pp. 1034-1042
    • Bu, G.1    Lu, W.2    Liu, C.C.3    Selander, K.4    Yoneda, T.5    Hall, C.6    Keller, E.T.7    Li, Y.8
  • 35
    • 12444280047 scopus 로고    scopus 로고
    • Metastatic breast cancer cells suppress osteoblast adhesion and differentiation
    • PubMed PMID: 15672867
    • Mercer RR, Miyasaka C, Mastro AM,. Metastatic breast cancer cells suppress osteoblast adhesion and differentiation. Clin Exp Metastasis 2004; 21: 427-35. PubMed PMID: 15672867.
    • (2004) Clin Exp Metastasis , vol.21 , pp. 427-435
    • Mercer, R.R.1    Miyasaka, C.2    Mastro, A.M.3
  • 36
    • 5144229126 scopus 로고    scopus 로고
    • Breast cancer cells induce osteoblast apoptosis: A possible contributor to bone degradation
    • PubMed PMID: 14743387
    • Mastro AM, Gay CV, Welch DR, et al., Breast cancer cells induce osteoblast apoptosis: a possible contributor to bone degradation. J Cell Biochem 2004; 91: 265-76. doi: 10.1002/jcb.10746. PubMed PMID: 14743387.
    • (2004) J Cell Biochem , vol.91 , pp. 265-276
    • Mastro, A.M.1    Gay, C.V.2    Welch, D.R.3
  • 37
    • 0030996171 scopus 로고    scopus 로고
    • Angiogenesis as a prognostic indicator of survival in non-small-cell lung carcinoma: A prospective study
    • PubMed PMID: 9196255
    • Fontanini G, Lucchi M, Vignati S, et al., Angiogenesis as a prognostic indicator of survival in non-small-cell lung carcinoma: a prospective study. J Natl Cancer Inst 1997; 89: 881-6. PubMed PMID: 9196255.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 881-886
    • Fontanini, G.1    Lucchi, M.2    Vignati, S.3
  • 38
    • 0032897455 scopus 로고    scopus 로고
    • Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours
    • PubMed PMID: 10360672; PubMed Central PMCID: PMC2362274
    • Speirs V, Atkin SL,. Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours. Br J Cancer 1999; 80: 898-903. doi: 10.1038/sj.bjc.6690438. PubMed PMID: 10360672; PubMed Central PMCID: PMC2362274.
    • (1999) Br J Cancer , vol.80 , pp. 898-903
    • Speirs, V.1    Atkin, S.L.2
  • 39
    • 0036192486 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts
    • PubMed PMID: 11882460
    • Mayr-Wohlfart U, Waltenberger J, Hausser H, et al., Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts. Bone 2002; 30: 472-7. PubMed PMID: 11882460.
    • (2002) Bone , vol.30 , pp. 472-477
    • Mayr-Wohlfart, U.1    Waltenberger, J.2    Hausser, H.3
  • 40
    • 0036339867 scopus 로고    scopus 로고
    • Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis
    • PubMed PMID: 11934855
    • Zelzer E, McLean W, Ng YS, et al., Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development 2002; 129: 1893-904. PubMed PMID: 11934855.
    • (2002) Development , vol.129 , pp. 1893-1904
    • Zelzer, E.1    McLean, W.2    Ng, Y.S.3
  • 41
    • 15544385929 scopus 로고    scopus 로고
    • Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair
    • PubMed PMID: 15642383
    • Zelzer E, Olsen BR,. Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair. Curr Top Dev Biol 2005; 65: 169-87. doi: 10.1016/S0070-2153(04)65006-X. PubMed PMID: 15642383.
    • (2005) Curr Top Dev Biol , vol.65 , pp. 169-187
    • Zelzer, E.1    Olsen, B.R.2
  • 42
    • 49649091570 scopus 로고    scopus 로고
    • Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma
    • PubMed PMID: 18450743
    • Fukaya Y, Shimada H, Wang LC, et al., Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma. J Biol Chem 2008; 283: 18573-81. doi: 10.1074/jbc.M803115200. PubMed PMID: 18450743.
    • (2008) J Biol Chem , vol.283 , pp. 18573-18581
    • Fukaya, Y.1    Shimada, H.2    Wang, L.C.3
  • 43
    • 84860503105 scopus 로고    scopus 로고
    • A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma
    • PubMed PMID: 22389450; PubMed Central PMCID: PMC3815584
    • Silverman AM, Nakata R, Shimada H, et al., A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma. Cancer Res 2012; 72: 2228-38. doi: 10.1158/0008-5472.CAN-11-2165. PubMed PMID: 22389450; PubMed Central PMCID: PMC3815584.
    • (2012) Cancer Res , vol.72 , pp. 2228-2238
    • Silverman, A.M.1    Nakata, R.2    Shimada, H.3
  • 44
    • 84872328323 scopus 로고    scopus 로고
    • LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis
    • PubMed PMID: 22864925
    • Piccolo E, Tinari N, Semeraro D, et al., LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis. J Mol Med 2013; 91: 83-94. doi: 10.1007/s00109-012-0936-6. PubMed PMID: 22864925.
    • (2013) J Mol Med , vol.91 , pp. 83-94
    • Piccolo, E.1    Tinari, N.2    Semeraro, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.