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Volumn 80, Issue 5-6, 1999, Pages 898-903

Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours

Author keywords

Angiogenesis; Breast; Cancer; VEGF

Indexed keywords

ANGIOGENIC FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 0032897455     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690438     Document Type: Article
Times cited : (64)

References (36)
  • 1
    • 0025866941 scopus 로고
    • Interleukin-6 is secreted by breast fibroblasts and stimulates 17β-estradiol oxidoreductase activity of MCF-7 cells: Possible paracrine regulation of breast 17β-estradiol levels
    • Adams EF, Rafferty B and White MC (1991) Interleukin-6 is secreted by breast fibroblasts and stimulates 17β-estradiol oxidoreductase activity of MCF-7 cells: possible paracrine regulation of breast 17β-estradiol levels. Int J Cancer 49: 118-121
    • (1991) Int J Cancer , vol.49 , pp. 118-121
    • Adams, E.F.1    Rafferty, B.2    White, M.C.3
  • 4
    • 0027981075 scopus 로고
    • Vascular endothelial growth factor receptor localisation and activation in human trophoblast and choriocarcinoma cells
    • Charnock-Jones DS, Sharkey AM, Boocock CA, Ahmed A, Plevin R, Ferrara N and Smith SK (1994) Vascular endothelial growth factor receptor localisation and activation in human trophoblast and choriocarcinoma cells. Biol Reprod 51: 524-530
    • (1994) Biol Reprod , vol.51 , pp. 524-530
    • Charnock-Jones, D.S.1    Sharkey, A.M.2    Boocock, C.A.3    Ahmed, A.4    Plevin, R.5    Ferrara, N.6    Smith, S.K.7
  • 5
    • 0030046481 scopus 로고    scopus 로고
    • Interleukin-6 induces the expression of vascular endothelial growth factor
    • Cohen T, Nahari D, Cerem LW, Neufeld G and Levi B-Z (1996) Interleukin-6 induces the expression of vascular endothelial growth factor. J Biol Chem 271: 736-741
    • (1996) J Biol Chem , vol.271 , pp. 736-741
    • Cohen, T.1    Nahari, D.2    Cerem, L.W.3    Neufeld, G.4    Levi, B.-Z.5
  • 6
    • 0030997316 scopus 로고    scopus 로고
    • Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients
    • Dirix LY, Vermeulen PB, Pawinski A, Prove A, Benoy I, de Pooter C, Martin M and van Oosterom AT (1997) Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients. Br J Cancer 76: 238-243
    • (1997) Br J Cancer , vol.76 , pp. 238-243
    • Dirix, L.Y.1    Vermeulen, P.B.2    Pawinski, A.3    Prove, A.4    Benoy, I.5    De Pooter, C.6    Martin, M.7    Van Oosterom, A.T.8
  • 7
    • 0031910169 scopus 로고    scopus 로고
    • Expression of growth factors, growth inhibiting factors and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops
    • de Jong JS, van Diest PJ, van der Valk P and Baak JPA (1998) Expression of growth factors, growth inhibiting factors and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops. J Pathol 184: 44-52
    • (1998) J Pathol , vol.184 , pp. 44-52
    • De Jong, J.S.1    Van Diest, P.J.2    Van Der Valk, P.A.3    Baak, J.P.A.4
  • 8
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor lor vascular endothelial growth factor
    • de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara F and Williams LT (1992) The fms-like tyrosine kinase, a receptor lor vascular endothelial growth factor. Science 255: 989-991
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3    Houck, K.4    Ferrara, F.5    Williams, L.T.6
  • 10
    • 0030808297 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptors in normal human testicular tissue
    • Ergun S, Kilic N, Fiedler W and Mukhopadhyay AK (1997) Vascular endothelial growth factor and its receptors in normal human testicular tissue. Mol Cell Endocrinol 131: 9-20
    • (1997) Mol Cell Endocrinol , vol.131 , pp. 9-20
    • Ergun, S.1    Kilic, N.2    Fiedler, W.3    Mukhopadhyay, A.K.4
  • 11
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N and Davis-Smyth T (1997) The biology of vascular endothelial growth factor. Endo Res 18: 4-25
    • (1997) Endo Res , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 12
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J (1990) What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 14
    • 0027326476 scopus 로고
    • Human melanoma cells but not normal melanocytes express vascular endothelial growth factor receptors
    • Gitay-Goren H, Halaban R and Neufeld G (1993) Human melanoma cells but not normal melanocytes express vascular endothelial growth factor receptors. Biochem Biophys Res Commun 190: 702-708
    • (1993) Biochem Biophys Res Commun , vol.190 , pp. 702-708
    • Gitay-Goren, H.1    Halaban, R.2    Neufeld, G.3
  • 15
    • 0030820127 scopus 로고    scopus 로고
    • Expression of cytokine messenger RNA in normal and neoplastic human breast tissue: Identification of interleukin-8 as a potential regulatory factor in breast tumours
    • Green AR, Green VL, White MC and Speirs V (1997) Expression of cytokine messenger RNA in normal and neoplastic human breast tissue: identification of interleukin-8 as a potential regulatory factor in breast tumours. Int J Cancer 72: 937-941
    • (1997) Int J Cancer , vol.72 , pp. 937-941
    • Green, A.R.1    Green, V.L.2    White, M.C.3    Speirs, V.4
  • 17
    • 0029664716 scopus 로고    scopus 로고
    • Coexpression of flt-1, flt-4 and KDR in freshly isolated and cultured human endothelial cells
    • Hewett PW and Murray JC (1996) Coexpression of flt-1, flt-4 and KDR in freshly isolated and cultured human endothelial cells. Biochem Biophys Res Commun 221: 697-702
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 697-702
    • Hewett, P.W.1    Murray, J.C.2
  • 18
    • 0027960791 scopus 로고
    • Mammary fibroblasts may influence breast tumour angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression
    • Hlatky L, Tsionou C, Hahnfeldt P and Coleman CN (1994) Mammary fibroblasts may influence breast tumour angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression. Cancer Res 54: 6083-6086
    • (1994) Cancer Res , vol.54 , pp. 6083-6086
    • Hlatky, L.1    Tsionou, C.2    Hahnfeldt, P.3    Coleman, C.N.4
  • 19
    • 0026502754 scopus 로고
    • Binding sites for vascular endothelial growth factor are localised on endothelial cells in adult rat tissues
    • Jakeman LB, Winer J, Bennett GL, Altar CA and Ferrara N (1992) Binding sites for vascular endothelial growth factor are localised on endothelial cells in adult rat tissues. J Clin Invest 89: 244-253
    • (1992) J Clin Invest , vol.89 , pp. 244-253
    • Jakeman, L.B.1    Winer, J.2    Bennett, G.L.3    Altar, C.A.4    Ferrara, N.5
  • 20
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a soluble form of the vascular endothelial growth factor receptor flt-1 and its heterodimerisation with KDR
    • Kendall RL, Wang G and Thomas KA (1996) Identification of a soluble form of the vascular endothelial growth factor receptor flt-1 and its heterodimerisation with KDR. Biochem Biophys Res Commun 226: 234-328
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 234-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 21
    • 0000004505 scopus 로고
    • VEGF/VPS: The angiogenesis factor found?
    • Klagsbrun M and Soker S (1993) VEGF/VPS: the angiogenesis factor found? Carr Biol 3: 699-702
    • (1993) Carr Biol , vol.3 , pp. 699-702
    • Klagsbrun, M.1    Soker, S.2
  • 23
    • 0031671095 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma
    • Linderholm B, Tavelin B, Grankvist K and Henriksson R (1998) Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma. J Clin Oncol 16: 3121-3128
    • (1998) J Clin Oncol , vol.16 , pp. 3121-3128
    • Linderholm, B.1    Tavelin, B.2    Grankvist, K.3    Henriksson, R.4
  • 24
    • 0000195548 scopus 로고    scopus 로고
    • Stimulation of the growth of MCF-7 and MDA-MB-468 breast cancer cells by vascular endothelial growth factor
    • Lu Q and Brodie A (1996) Stimulation of the growth of MCF-7 and MDA-MB-468 breast cancer cells by vascular endothelial growth factor. Proc Am Assoc Cancer Res 37: 1499
    • (1996) Proc Am Assoc Cancer Res , vol.37 , pp. 1499
    • Lu, Q.1    Brodie, A.2
  • 25
    • 0031800113 scopus 로고    scopus 로고
    • Differential expression of vascular endothelial growth factor mRNA vs. Protein inform expression in human breast cancer and relationship to cIF-4E
    • Scott PAE, Smith K, Poulsom R, De Benedetti A, Bicknell R and Harris AL (1998) Differential expression of vascular endothelial growth factor mRNA vs. protein inform expression in human breast cancer and relationship to cIF-4E. Br J Cancer 77: 2120-2128
    • (1998) Br J Cancer , vol.77 , pp. 2120-2128
    • Scott, P.A.E.1    Smith, K.2    Poulsom, R.3    De Benedetti, A.4    Bicknell, R.5    Harris, A.L.6
  • 26
    • 0028798083 scopus 로고
    • A unique signal transduction pathway for the flt-1 tyrosine kinase receptor, a receptor for vascular endothelial growth factor
    • Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S and Shibuya MA (1995) A unique signal transduction pathway for the flt-1 tyrosine kinase receptor, a receptor for vascular endothelial growth factor. Oncogene 10: 135-147
    • (1995) Oncogene , vol.10 , pp. 135-147
    • Seetharam, L.1    Gotoh, N.2    Maru, Y.3    Neufeld, G.4    Yamaguchi, S.5    Shibuya, M.A.6
  • 27
    • 0029867961 scopus 로고    scopus 로고
    • Collagenase III: A superior enzyme for complete disaggregation and improved viability of normal and malignant human breast tissue
    • Speirs V, Green AR and White MC (1996a) Collagenase III: a superior enzyme for complete disaggregation and improved viability of normal and malignant human breast tissue. In Vitro Cell Dev Biol 32: 72-74
    • (1996) Vitro Cell Dev Biol , vol.32 , pp. 72-74
    • Speirs, V.1    Green, A.R.2    White, M.C.3
  • 28
    • 0029948150 scopus 로고    scopus 로고
    • A comparative study of cytokine gene transcripts in normal and malignant breast tissue and primary cell cultures derived from the same tissue samples
    • Speirs V, Green AR and White MC (1996b) A comparative study of cytokine gene transcripts in normal and malignant breast tissue and primary cell cultures derived from the same tissue samples. Int J Cancer 66: 551-556
    • (1996) Int J Cancer , vol.66 , pp. 551-556
    • Speirs, V.1    Green, A.R.2    White, M.C.3
  • 31
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fides JC and Abraham JA (1991) The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 266: 11947-11954
    • (1991) J Biol Chem , vol.266 , pp. 11947-11954
    • Tischer, E.1    Mitchell, R.2    Hartman, T.3    Silva, M.4    Gospodarowicz, D.5    Fides, J.C.6    Abraham, J.A.7
  • 32
    • 0027373841 scopus 로고
    • Tumour angiogenesis is an independent prognostic indicator in primary breast carcinoma
    • Toi M, Kashitani L and Tominaga T (1993) Tumour angiogenesis is an independent prognostic indicator in primary breast carcinoma. Int J Cancer 55: 371-374
    • (1993) Int J Cancer , vol.55 , pp. 371-374
    • Toi, M.1    Kashitani, L.2    Tominaga, T.3
  • 34
    • 0027997863 scopus 로고
    • Different signal transduction properties of KDR and Flt-1, two receptors for vascular endothelial growth factor
    • Waltenberger J, Claesson-Welch L, Siegbahn A, Shibuya M and Heldin C-H (1994) Different signal transduction properties of KDR and Flt-1, two receptors for vascular endothelial growth factor. J Biol Chem 269: 26988-26955
    • (1994) J Biol Chem , vol.269 , pp. 26988-126955
    • Waltenberger, J.1    Claesson-Welch, L.2    Siegbahn, A.3    Shibuya, M.4    Heldin, C.-H.5
  • 35
    • 0029935566 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer
    • Yoshiji H, Gomez DE, Shibuya M and Thorgeirsson UP (1996) Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer. Cancer Res 56: 2013-2016
    • (1996) Cancer Res , vol.56 , pp. 2013-2016
    • Yoshiji, H.1    Gomez, D.E.2    Shibuya, M.3    Thorgeirsson, U.P.4
  • 36
    • 0026083903 scopus 로고
    • Tumour angiogenesis and metastasis: Correlation in invasive breast cancer
    • Weidner N, Semple JP, Welch WR and Folkman J (1991) Tumour angiogenesis and metastasis: correlation in invasive breast cancer. N Engl J Med 324: 1-8
    • (1991) N Engl J Med , vol.324 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4


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