메뉴 건너뛰기




Volumn 11, Issue 4, 2015, Pages 998-1012

Changes in urinary metabolic profiles of colorectal cancer patients enrolled in a prospective cohort study (ColoCare)

Author keywords

Biomarkers; Cohort; Colorectal cancer; Gas chromatography mass spectrometry (GC MS); Metabolomics; Nuclear magnetic resonance (NMR)

Indexed keywords

1 METHYLNICOTINAMIDE; 2 HYDROXYGLUTARIC ACID; 2, 3 BUTANEDIOL; ACONITIC ACID; ARABINITOL; BIOLOGICAL MARKER; BUTYRIC ACID; CARNITINE; CYSTINE; DOPAMINE; GLUCURONIDE; GLUTAMIC ACID; GLUTAMINE; GLYCEROL; GUAIACOL; HIPPURIC ACID; HISTIDINE; HYDROQUINONE; HYPOXANTHINE; INDICAN; INOSITOL; N ACETYLGLUCOSAMINE; PARA CRESOL; PYROGALLOL; PYROGLUTAMIC ACID; SUGAR ACID; TARTARIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG; UREA; XYLOSE;

EID: 84931564158     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-014-0758-3     Document Type: Article
Times cited : (40)

References (58)
  • 1
    • 84855884306 scopus 로고    scopus 로고
    • Metabolic features of the tumor microenvironment of gastric cancer and the link to the systemic macroenvironment
    • COI: 1:CAS:528:DC%2BC38XosFOmuw%3D%3D
    • Aa, J., et al. (2012). Metabolic features of the tumor microenvironment of gastric cancer and the link to the systemic macroenvironment. Metabolomics,8, 164–173.
    • (2012) Metabolomics , vol.8 , pp. 164-173
    • Aa, J.1
  • 3
    • 84861002231 scopus 로고    scopus 로고
    • MetaMapp: Mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity
    • PID: 22591066
    • Barupal, D. K., et al. (2012). MetaMapp: Mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity. BMC Bioinformatics,13, 99.
    • (2012) BMC Bioinformatics , vol.13 , pp. 99
    • Barupal, D.K.1
  • 5
    • 0024348166 scopus 로고
    • Nitrogen excretion in cancer cachexia and its modification by a high fat diet in mice
    • COI: 1:CAS:528:DyaL1MXkvFKjt78%3D, PID: 2736521
    • Beck, S. A., & Tisdale, M. J. (1989). Nitrogen excretion in cancer cachexia and its modification by a high fat diet in mice. Cancer Research,49, 3800–3804.
    • (1989) Cancer Research , vol.49 , pp. 3800-3804
    • Beck, S.A.1    Tisdale, M.J.2
  • 6
    • 31544467069 scopus 로고    scopus 로고
    • Accuracy of computed tomography and magnetic resonance imaging in the detection of lymph node involvement in cervix carcinoma
    • PID: 15999213
    • Bellomi, M., et al. (2005). Accuracy of computed tomography and magnetic resonance imaging in the detection of lymph node involvement in cervix carcinoma. European Radiology,15, 2469–2474.
    • (2005) European Radiology , vol.15 , pp. 2469-2474
    • Bellomi, M.1
  • 8
    • 84885357393 scopus 로고    scopus 로고
    • Laparoscopic vs. open approach for colorectal cancer: Evolution over time of minimal invasive surgery
    • Biondi, A., et al. (2013). Laparoscopic vs. open approach for colorectal cancer: Evolution over time of minimal invasive surgery. BMC surgery,13, 1471–2482.
    • (2013) BMC surgery , vol.13 , pp. 1471-2482
    • Biondi, A.1
  • 9
    • 0017040869 scopus 로고
    • The production of urinary phenols by gut bacteria and their possible role in the causation of large bowel cancer
    • COI: 1:CAS:528:DyaE1cXltVGntro%3D, PID: 826152
    • Bone, E., Tamm, A., & Hill, M. (1976). The production of urinary phenols by gut bacteria and their possible role in the causation of large bowel cancer. American Journal of Clinical Nutrition,29, 1448–1454.
    • (1976) American Journal of Clinical Nutrition , vol.29 , pp. 1448-1454
    • Bone, E.1    Tamm, A.2    Hill, M.3
  • 10
    • 84965025748 scopus 로고
    • The tumor-promoting action of phenol and related compounds for mouse skin
    • COI: 1:CAS:528:DyaG1MXnvVOhuw%3D%3D, PID: 13652126
    • Boutwell, R. K., & Bosch, D. K. (1959). The tumor-promoting action of phenol and related compounds for mouse skin. Cancer Research,19, 413–424.
    • (1959) Cancer Research , vol.19 , pp. 413-424
    • Boutwell, R.K.1    Bosch, D.K.2
  • 11
    • 0024162363 scopus 로고
    • Conversion of IQ, a dietary pyrolysis carcinogen to a direct-acting mutagen by normal intestinal bacteria of humans
    • COI: 1:CAS:528:DyaL1MXptVentQ%3D%3D, PID: 3200256
    • Carman, R. J., Van Tassell, R. L., Kingston, D. G., Bashir, M., & Wilkins, T. D. (1988). Conversion of IQ, a dietary pyrolysis carcinogen to a direct-acting mutagen by normal intestinal bacteria of humans. Mutation Research,206, 335–342.
    • (1988) Mutation Research , vol.206 , pp. 335-342
    • Carman, R.J.1    Van Tassell, R.L.2    Kingston, D.G.3    Bashir, M.4    Wilkins, T.D.5
  • 12
    • 60849139445 scopus 로고    scopus 로고
    • Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS)
    • COI: 1:CAS:528:DC%2BD1cXhsVOnsLnN, PID: 19063642
    • Chan, E. C., et al. (2009). Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS). Journal of Proteome Research,8, 352–361.
    • (2009) Journal of Proteome Research , vol.8 , pp. 352-361
    • Chan, E.C.1
  • 13
    • 84863024905 scopus 로고    scopus 로고
    • Distinct urinary metabolic profile of human colorectal cancer
    • COI: 1:CAS:528:DC%2BC3MXhsF2jsrzL, PID: 22148915
    • Cheng, Y., et al. (2012). Distinct urinary metabolic profile of human colorectal cancer. Journal of Proteome Research,11, 1354–1363.
    • (2012) Journal of Proteome Research , vol.11 , pp. 1354-1363
    • Cheng, Y.1
  • 14
    • 79955547561 scopus 로고    scopus 로고
    • The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
    • Chowdhury, R., Yeoh, K. K., Tian, Y. M., Hillringhaus, L., Bagg, E. A., Rose, N. R.,et al. (2011). The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Reports, 12(5), 463–469. doi:10.1038/embor.2011.43
    • (2011) EMBO Reports , vol.12 , Issue.5 , pp. 463-469
    • Chowdhury, R.1    Yeoh, K.K.2    Tian, Y.M.3    Hillringhaus, L.4    Bagg, E.A.5    Rose, N.6
  • 15
    • 54349088296 scopus 로고    scopus 로고
    • Metabolite profiling of human colon carcinoma: Deregulation of TCA cycle and amino acid turnover
    • PID: 18799019
    • Denkert, C., et al. (2008). Metabolite profiling of human colon carcinoma: Deregulation of TCA cycle and amino acid turnover. Molecular Cancer,7, 72.
    • (2008) Molecular Cancer , vol.7 , pp. 72
    • Denkert, C.1
  • 16
    • 33646576169 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tumor metastasis
    • COI: 1:CAS:528:DC%2BD28Xktlaksr4%3D, PID: 16680569
    • Deryugina, E. I., & Quigley, J. P. (2006). Matrix metalloproteinases and tumor metastasis. Cancer and Metastasis Reviews,25, 9–34.
    • (2006) Cancer and Metastasis Reviews , vol.25 , pp. 9-34
    • Deryugina, E.I.1    Quigley, J.P.2
  • 17
    • 79959913950 scopus 로고    scopus 로고
    • Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
    • COI: 1:CAS:528:DC%2BC3MXotlCmtL8%3D, PID: 21720319
    • Dunn, W. B., et al. (2011). Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nature Protocols,6, 1060–1083.
    • (2011) Nature Protocols , vol.6 , pp. 1060-1083
    • Dunn, W.B.1
  • 18
    • 84860791945 scopus 로고    scopus 로고
    • Serum metabolomic profile as a means to distinguish stage of colorectal cancer
    • Farshidfar, F., et al. (2012). Serum metabolomic profile as a means to distinguish stage of colorectal cancer. Genome Medicine,4, 2–13.
    • (2012) Genome Medicine , vol.4 , pp. 2-13
    • Farshidfar, F.1
  • 19
    • 84875804295 scopus 로고    scopus 로고
    • Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
    • COI: 1:STN:280:DC%2BC3svlsVantg%3D%3D, PID: 23485231
    • Ferlay, J., et al. (2013). Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012. European Journal of Cancer,49, 1374–1403.
    • (2013) European Journal of Cancer , vol.49 , pp. 1374-1403
    • Ferlay, J.1
  • 20
  • 24
    • 33947216093 scopus 로고    scopus 로고
    • A comprehensive urinary metabolomic approach for identifying kidney cancer
    • COI: 1:CAS:528:DC%2BD2sXjsVWiurc%3D, PID: 17316536
    • Kind, T., Tolstikov, V., Fiehn, O., & Weiss, R. H. (2007). A comprehensive urinary metabolomic approach for identifying kidney cancer. Analytical Biochemistry,363, 185–195.
    • (2007) Analytical Biochemistry , vol.363 , pp. 185-195
    • Kind, T.1    Tolstikov, V.2    Fiehn, O.3    Weiss, R.H.4
  • 25
    • 80052041295 scopus 로고    scopus 로고
    • Serum fatty acid profiling of colorectal cancer by gas chromatography/mass spectrometry
    • COI: 1:CAS:528:DC%2BC3MXhtVyrsLfP, PID: 21861667
    • Kondo, Y., et al. (2011). Serum fatty acid profiling of colorectal cancer by gas chromatography/mass spectrometry. Biomarkers in Medicine,5, 451–460.
    • (2011) Biomarkers in Medicine , vol.5 , pp. 451-460
    • Kondo, Y.1
  • 26
    • 84864046667 scopus 로고    scopus 로고
    • Serum amino acid profiles and their alterations in colorectal cancer
    • COI: 1:CAS:528:DC%2BC38XhtVegt7rN, PID: 22833708
    • Leichtle, A. B., et al. (2012). Serum amino acid profiles and their alterations in colorectal cancer. Metabolomics,8, 643–653.
    • (2012) Metabolomics , vol.8 , pp. 643-653
    • Leichtle, A.B.1
  • 28
    • 84876889621 scopus 로고    scopus 로고
    • What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
    • COI: 1:CAS:528:DC%2BC3sXnsl2gtro%3D
    • Losman, J. A., & Kaelin, W. G., Jr. (2013). What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer. Genes & Development,27, 836–852.
    • (2013) Genes & Development , vol.27 , pp. 836-852
    • Losman, J.A.1    Kaelin, W.G.2
  • 29
    • 70450253541 scopus 로고    scopus 로고
    • Ultra-high performance liquid chromatography–mass spectrometry for the metabolomic analysis of urine in colorectal cancer
    • COI: 1:CAS:528:DC%2BD1MXhsVehsrfP, PID: 19117128
    • Ma, Y. L., et al. (2009). Ultra-high performance liquid chromatography–mass spectrometry for the metabolomic analysis of urine in colorectal cancer. Digestive Diseases and Sciences,54, 2655–2662.
    • (2009) Digestive Diseases and Sciences , vol.54 , pp. 2655-2662
    • Ma, Y.L.1
  • 30
    • 78650314877 scopus 로고    scopus 로고
    • Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study
    • COI: 1:CAS:528:DC%2BC3MXisFajsw%3D%3D, PID: 21176209
    • Maeda, J., et al. (2010). Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study. BMC Cancer,10, 690–698.
    • (2010) BMC Cancer , vol.10 , pp. 690-698
    • Maeda, J.1
  • 31
    • 60549109691 scopus 로고    scopus 로고
    • Development and validation of a gas chromatography/mass spectrometry method for the metabolic profiling of human colon tissue
    • COI: 1:CAS:528:DC%2BD1MXitVakt70%3D, PID: 19140133
    • Mal, M., Koh, P. K., Cheah, P. Y., & Chan, E. C. Y. (2009). Development and validation of a gas chromatography/mass spectrometry method for the metabolic profiling of human colon tissue. Rapid Communications in Mass Spectrometry,23, 487–494.
    • (2009) Rapid Communications in Mass Spectrometry , vol.23 , pp. 487-494
    • Mal, M.1    Koh, P.K.2    Cheah, P.Y.3    Chan, E.C.Y.4
  • 32
    • 84861235132 scopus 로고    scopus 로고
    • Metabotyping of human colorectal cancer using two-dimensional gas chromatography mass spectrometry
    • COI: 1:CAS:528:DC%2BC38XivFWqu74%3D, PID: 22374317
    • Mal, M., Koh, P. K., Cheah, P. Y., & Chan, E. C. Y. (2012). Metabotyping of human colorectal cancer using two-dimensional gas chromatography mass spectrometry. Analytical and Bioanalytical Chemistry,403, 483–493.
    • (2012) Analytical and Bioanalytical Chemistry , vol.403 , pp. 483-493
    • Mal, M.1    Koh, P.K.2    Cheah, P.Y.3    Chan, E.C.Y.4
  • 33
    • 79956359184 scopus 로고    scopus 로고
    • Towards the Human Colorectal Cancer Microbiome
    • COI: 1:CAS:528:DC%2BC3MXmvVKrsLY%3D, PID: 21647227
    • Marchesi, J. R., et al. (2011). Towards the Human Colorectal Cancer Microbiome. PLoS One,6, e20447.
    • (2011) PLoS One , vol.6 , pp. 20447
    • Marchesi, J.R.1
  • 34
    • 80052526020 scopus 로고    scopus 로고
    • Plasma free amino acid profiling of five types of cancer patients and its application for early detection
    • COI: 1:CAS:528:DC%2BC3MXht1ChsLfN, PID: 21915291
    • Miyagi, Y., et al. (2011). Plasma free amino acid profiling of five types of cancer patients and its application for early detection. PLoS One,6, e24143.
    • (2011) PLoS One , vol.6 , pp. 24143
    • Miyagi, Y.1
  • 35
    • 0042848767 scopus 로고    scopus 로고
    • Tryptophan and the immune response
    • COI: 1:CAS:528:DC%2BD3sXmvFSmtLw%3D, PID: 12848846
    • Moffett, J. R., & Namboodiri, M. A. (2003). Tryptophan and the immune response. Immunology and Cell Biology,81, 247–265.
    • (2003) Immunology and Cell Biology , vol.81 , pp. 247-265
    • Moffett, J.R.1    Namboodiri, M.A.2
  • 37
    • 84863844396 scopus 로고    scopus 로고
    • A novel serum metabolomics-based diagnostic approach for colorectal cancer
    • COI: 1:CAS:528:DC%2BC38XhtVKrsr%2FJ, PID: 22792336
    • Nishiumi, S., et al. (2012). A novel serum metabolomics-based diagnostic approach for colorectal cancer. Plos One,7, e40459.
    • (2012) Plos One , vol.7 , pp. 40459
    • Nishiumi, S.1
  • 38
    • 84872777716 scopus 로고    scopus 로고
    • Molecular diagnostics and personalized medicine in oncology: challenges and opportunities
    • COI: 1:CAS:528:DC%2BC3sXhtFGhu7w%3D, PID: 22991232
    • Normanno, N., et al. (2013). Molecular diagnostics and personalized medicine in oncology: challenges and opportunities. Journal of Cellular Biochemistry,114, 514–524.
    • (2013) Journal of Cellular Biochemistry , vol.114 , pp. 514-524
    • Normanno, N.1
  • 39
    • 80054041992 scopus 로고    scopus 로고
    • An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
    • COI: 1:CAS:528:DC%2BC3MXht1ylt7nI, PID: 21976023
    • Opitz, C. A., et al. (2011). An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature,478, 197–203.
    • (2011) Nature , vol.478 , pp. 197-203
    • Opitz, C.A.1
  • 40
    • 0034063398 scopus 로고    scopus 로고
    • Generation of reactive oxygen species by the faecal matrix
    • COI: 1:CAS:528:DC%2BD3cXhtFyrtbw%3D, PID: 10644317
    • Owen, R. W., Spiegelhalder, B., & Bartsch, H. (2000). Generation of reactive oxygen species by the faecal matrix. Gut,46, 225–232.
    • (2000) Gut , vol.46 , pp. 225-232
    • Owen, R.W.1    Spiegelhalder, B.2    Bartsch, H.3
  • 41
    • 0022465302 scopus 로고
    • Role of branched-chain 2-oxo acid dehydrogenase and pyruvate dehydrogenase in 2-oxobutyrate metabolism
    • COI: 1:CAS:528:DyaL28Xht1Glsrc%3D, PID: 3718468
    • Paxton, R., Scislowski, P. W., Davis, E. J., & Harris, R. A. (1986). Role of branched-chain 2-oxo acid dehydrogenase and pyruvate dehydrogenase in 2-oxobutyrate metabolism. Biochemical Journal,234, 295–303.
    • (1986) Biochemical Journal , vol.234 , pp. 295-303
    • Paxton, R.1    Scislowski, P.W.2    Davis, E.J.3    Harris, R.A.4
  • 42
    • 33845631556 scopus 로고    scopus 로고
    • Pathway analysis of kidney cancer using proteomics and metabolic profiling
    • Perroud, B., et al. (2006). Pathway analysis of kidney cancer using proteomics and metabolic profiling. Molecular Cancer,5, 1–17.
    • (2006) Molecular Cancer , vol.5
    • Perroud, B.1
  • 43
    • 77954772536 scopus 로고    scopus 로고
    • MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
    • PID: 20650010
    • Pluskal, T., Castillo, S., Villar-Briones, A., & Oresic, M. (2010). MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data. BMC Bioinformatics,11, 395–406.
    • (2010) BMC Bioinformatics , vol.11 , pp. 395-406
    • Pluskal, T.1    Castillo, S.2    Villar-Briones, A.3    Oresic, M.4
  • 44
    • 26444570010 scopus 로고    scopus 로고
    • Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations
    • COI: 1:CAS:528:DC%2BD2MXmt1ert78%3D, PID: 15987702
    • Pollard, P. J., et al. (2005). Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Human Molecular Genetics,14, 2231–2239.
    • (2005) Human Molecular Genetics , vol.14 , pp. 2231-2239
    • Pollard, P.J.1
  • 45
    • 70350028279 scopus 로고    scopus 로고
    • Serum metabolite profiling of human colorectal cancer using GC–TOFMS and UPLC–QTOFMS
    • COI: 1:CAS:528:DC%2BD1MXhtV2murrM, PID: 19678709
    • Qiu, Y. P., et al. (2009). Serum metabolite profiling of human colorectal cancer using GC–TOFMS and UPLC–QTOFMS. Journal of Proteome Research,8, 4844–4850.
    • (2009) Journal of Proteome Research , vol.8 , pp. 4844-4850
    • Qiu, Y.P.1
  • 46
    • 77949822339 scopus 로고    scopus 로고
    • Urinary metabonomic study on colorectal cancer
    • COI: 1:CAS:528:DC%2BC3cXitV2hs70%3D, PID: 20121166
    • Qiu, Y. P., et al. (2010). Urinary metabonomic study on colorectal cancer. Journal of Proteome Research,9, 1627–1634.
    • (2010) Journal of Proteome Research , vol.9 , pp. 1627-1634
    • Qiu, Y.P.1
  • 47
    • 77949479965 scopus 로고    scopus 로고
    • Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection
    • Ritchie, S. A., et al. (2010). Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. BMC Medicine,8, 1–20.
    • (2010) BMC Medicine , vol.8
    • Ritchie, S.A.1
  • 48
    • 0020057321 scopus 로고
    • Transaminative metabolism of alpha-amino-n-butyrate in rats
    • COI: 1:CAS:528:DyaL38XhtVWmsro%3D, PID: 7078416
    • Steele, R. D. (1982). Transaminative metabolism of alpha-amino-n-butyrate in rats. Metabolism,31, 318–325.
    • (1982) Metabolism , vol.31 , pp. 318-325
    • Steele, R.D.1
  • 49
    • 34748888866 scopus 로고    scopus 로고
    • Proposed minimum reporting standards for chemical analysis
    • COI: 1:CAS:528:DC%2BD2sXhtFOntbvL, PID: 24039616
    • Sumner, L., et al. (2007). Proposed minimum reporting standards for chemical analysis. Metabolomics,3, 211–221.
    • (2007) Metabolomics , vol.3 , pp. 211-221
    • Sumner, L.1
  • 50
    • 78649944454 scopus 로고    scopus 로고
    • Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol
    • COI: 1:CAS:528:DC%2BC3cXhsFGqu7rE, PID: 21151972
    • Thysell, E., et al. (2010). Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol. PLoS One,5, e14175.
    • (2010) PLoS One , vol.5 , pp. 14175
    • Thysell, E.1
  • 51
    • 33747019547 scopus 로고    scopus 로고
    • Centering, scaling, and transformations: Improving the biological information content of metabolomics data
    • PID: 16762068
    • van den Berg, R., Hoefsloot, H., Westerhuis, J., Smilde, A., & van der Werf, M. (2006). Centering, scaling, and transformations: Improving the biological information content of metabolomics data. BMC Genomics,7, 142.
    • (2006) BMC Genomics , vol.7 , pp. 142
    • van den Berg, R.1    Hoefsloot, H.2    Westerhuis, J.3    Smilde, A.4    van der Werf, M.5
  • 52
    • 77956518768 scopus 로고    scopus 로고
    • Urinary metabolic profiling of colorectal carcinoma based on online affinity solid phase extraction-high performance liquid chromatography and ultra performance liquid chromatography–mass spectrometry
    • COI: 1:CAS:528:DC%2BC3cXhtFamtrzP, PID: 20617254
    • Wang, W. Z., et al. (2010). Urinary metabolic profiling of colorectal carcinoma based on online affinity solid phase extraction-high performance liquid chromatography and ultra performance liquid chromatography–mass spectrometry. Molecular Biosystems,6, 1947–1955.
    • (2010) Molecular Biosystems , vol.6 , pp. 1947-1955
    • Wang, W.Z.1
  • 53
    • 58949091234 scopus 로고    scopus 로고
    • Normalization strategies for metabonomic analysis of urine samples
    • COI: 1:CAS:528:DC%2BD1MXhtlShtbw%3D
    • Warrack, B. M., et al. (2009). Normalization strategies for metabonomic analysis of urine samples. Journal of Chromatography B,877, 547–552.
    • (2009) Journal of Chromatography B , vol.877 , pp. 547-552
    • Warrack, B.M.1
  • 54
    • 67650388695 scopus 로고    scopus 로고
    • Metabolomic profiling of human urine in hepatocellular carcinoma patients using gas chromatography/mass spectrometry
    • COI: 1:CAS:528:DC%2BD1MXoslGnsbo%3D, PID: 19616694
    • Wu, H., et al. (2009). Metabolomic profiling of human urine in hepatocellular carcinoma patients using gas chromatography/mass spectrometry. Analytica Chimica Acta,648, 98–104.
    • (2009) Analytica Chimica Acta , vol.648 , pp. 98-104
    • Wu, H.1
  • 55
    • 84875552323 scopus 로고    scopus 로고
    • Translational biomarker discovery in clinical metabolomics: An introductory tutorial
    • COI: 1:CAS:528:DC%2BC3sXksF2msb8%3D, PID: 23543913
    • Xia, J., Broadhurst, D., Wilson, M., & Wishart, D. S. (2013). Translational biomarker discovery in clinical metabolomics: An introductory tutorial. Metabolomics,9, 280–299.
    • (2013) Metabolomics , vol.9 , pp. 280-299
    • Xia, J.1    Broadhurst, D.2    Wilson, M.3    Wishart, D.S.4
  • 57
    • 65349128823 scopus 로고    scopus 로고
    • An optimized buffer system for NMR-based urinary metabonomics with effective pH control, chemical shift consistency and dilution minimization
    • COI: 1:CAS:528:DC%2BD1MXkslartr4%3D, PID: 19381385
    • Xiao, C., Hao, F., Qin, X., Wang, Y., & Tang, H. (2009). An optimized buffer system for NMR-based urinary metabonomics with effective pH control, chemical shift consistency and dilution minimization. Analyst,134, 916–925.
    • (2009) Analyst , vol.134 , pp. 916-925
    • Xiao, C.1    Hao, F.2    Qin, X.3    Wang, Y.4    Tang, H.5
  • 58
    • 84862580679 scopus 로고    scopus 로고
    • Metabolite profiling of plasma and urine from rats with TNBS-induced acute colitis using UPLC–ESI–QTOF–MS-based metabonomics—A pilot study
    • COI: 1:CAS:528:DC%2BC38XpvFOgurY%3D, PID: 22520047
    • Zhang, X., et al. (2012). Metabolite profiling of plasma and urine from rats with TNBS-induced acute colitis using UPLC–ESI–QTOF–MS-based metabonomics—A pilot study. FEBS Journal,279, 2322–2338.
    • (2012) FEBS Journal , vol.279 , pp. 2322-2338
    • Zhang, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.