Vitamin D Receptor Gene Polymorphism and the Risk of Multiple Sclerosis in South Eastern of Iran

Journal of Molecular Neuroscience

Volumn 56, Issue 3, 2015, Pages 572-576

  Narooie Nejad, Mehrnaz ^a   Moossavi, Maryam ^b   Torkamanzehi, Adam ^b   Moghtaderi, Ali ^a   Salimi, Saeedeh ^a,c  

^a ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF SISTAN AND BALUCHESTAN   (Iran)

^c ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Multiple sclerosis; PCR RFLP; VDR polymorphism; Vitamin D

Indexed keywords

VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR;

ADULT; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; IRAN; IRANIAN PEOPLE; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; GENETICS;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; FEMALE; HUMANS; IRAN; MALE; MULTIPLE SCLEROSIS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CALCITRIOL;

EID: 84931560846     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-015-0513-x     Document Type: Article

References (38)

1. Adorini L, Penna G (2008) Control of autoimmune diseases by the vitamin D endocrine system. Nat Clin Pract Rheumatol 4:404–412
2. Barrat FJ, Cua DJ, Boonstra A et al (2002) In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195:603–616
3. Boonstra A, Barrat FJ, Crain C et al (2001) 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol 167:4974–4980
4. Brown AJ, Dusso A, Slatopolsky E (1999) Vitamin D. Am J PhysiolRenal Physiol 277:F157–F175
5. Calabresi PA (2004) Diagnosis and management of multiple sclerosis. Am Fam Physician 70:1935–1944
6. Dickinson JL, Perera DI, van der Mei AF et al (2009) Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 vitamin D receptor variant in this interaction. Mult Scler 15:563–570
7. Durrin LK, Haile RW, Ingles SA et al (1999) Vitamin D receptor 3'-untranslated region polymorphisms: lack of effect on mRNA stability. Biochim Biophys Acta 1453:311–320
8. Fukazawa T, Yabe I, Kikuchi S et al (1999) Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese. J Neurol Sci 166:47–52
9. Garcia-Martin E, Agundez JA, Martinez C et al (2013) Vitamin D3 receptor (VDR) gene rs2228570 (Fok1) and rs731236 (Taq1) variants are not associated with the risk for multiple sclerosis: results of a new study and a meta-analysis. PLoS One 8:e65487
10. Gorman S, Kuritzky LA, Judge MA et al (2007) Topically applied 1,25-dihydroxyvitamin D3 enhances the suppressive activity of CD4 + CD25+ cells in the draining lymph nodes. J Immunol 179:6273–6283
11. Hashemi M, Moazeni-Roodi AK, Fazaeli A et al (2010) Lack of association between paraoxonase-1 Q192R polymorphism and rheumatoid arthritis in southeast Iran. Genet Mol Res 9:333–339
12. Haussler MR, Jurutka PW, Mizwicki M et al (2011) Vitamin D receptor (VDR)-mediated actions of 1alpha,25(OH)(2) vitamin D(3): genomic and non-genomic mechanisms. Best Pract Res Clin Endocrinol Metab 25:543–559
13. Hewer S, Lucas R, van der Mei I, et al (2013) Vitamin D and multiple sclerosis. J Clin Neurosci
14. Izadi S, Nikseresht A, Sharifian M, et al (2013) Significant increase in the prevalence of multiple sclerosis in Iran; a report on the patients receiving beta-interferons in different provinces. Iran J Neurol Vol 12
15. Jurutka PW, Whitfield GK, Hsieh JC et al (2001) Molecular nature of the vitamin D receptor and its role in regulation of gene expression. Rev Endocr Metab Disord 2:203–216
16. Moghtaderi A, Rakhshanizadeh F, Shahraki-Ibrahimi S (2013a) Incidence and prevalence of multiple sclerosis in southeastern Iran. Clin Neurol Neurosurg 115:304–308
17. Moghtaderi A, Tamadon GH, Haghighi F (2013b) 25-hydroxyvitamin D3 concentration in serum and cerebrospinal fluid of patients with remitting-relapse multiple sclerosis. Prague Med Rep 114:162–171
18. Mount HT (1973) Multiple sclerosis and other demyelinating diseases. Can Med Assoc J 108:1356, passim
19. Navikas V, Link H (1996) Review: cytokines and the pathogenesis of multiple sclerosis. J Neurosci Res 45:322–333
20. Niedziela N, Adamczyk-Sowa M and Pierzchala K (2013) Epidemiology and clinical record of multiple sclerosis in selected countries: a systematic review. Int J Neurosci
21. Partridge JM, Weatherby SJ, Woolmore JA et al (2004) Susceptibility and outcome in MS: associations with polymorphisms in pigmentation-related genes. Neurology 62:2323–2325
22. Polman CH, Reingold SC, Edan G et al (2005) Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 58:840–846
23. Rajakumar K (2003) Vitamin D, cod-liver oil, sunlight, and rickets: a historical perspective. Pediatrics 112:e132–135
24. Shojapuor M, Mosayebi G, Ghasami K et al (2012) Vitamin D receptor gene polymorphism in patients with multiple sclerosis in Markazi Province. (AMUJ) 15:34–39
25. Simon KC, Munger KL, Xing Y et al (2010) Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis. Mult Scler 16:133–138
26. Simpson S Jr, Blizzard L, Otahal P et al (2011) Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis. J Neurol Neurosurg Psychiatry 82:1132–1141
27. Sioka C, Papakonstantinou S, Markoula S et al (2011) Vitamin D receptor gene polymorphisms in multiple sclerosis patients in northwest Greece. J Negat Results Biomed 10:3
28. Smolders J, Menheere P, Kessels A et al (2008) Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis. Mult Scler 14:1220–1224
29. Smolders J, Damoiseaux J, Menheere P et al (2009a) FokI vitamin D receptor gene polymorphism (rs10735810) and vitamin D metabolism in multiple sclerosis. J Neuroimmunol 207:117–121
30. Smolders J, Peelen E, Thewissen M et al (2009b) The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis. Autoimmun Rev 8:621–626
31. Steckley JL, Dyment DA, Sadovnick AD et al (2000) Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients. Canadian Collaborative Study Group Neurol 54:729–732
32. Thomasset M (1994) Vitamin D and the immune system. Pathol Biol (Paris) 42:163–172
33. Tizaoui K, Berraies A, Hamdi B et al (2014) Association of vitamin D receptor gene polymorphisms with asthma risk: systematic review and updated meta-analysis of case—control studies. Lung 192:955–965
34. Uitterlinden AG, Fang Y, Van Meurs JB et al (2004a) Genetics and biology of vitamin D receptor polymorphisms. Gene 338:143–156
35. Uitterlinden AG, Fang Y, van Meurs JB et al (2004b) Vitamin D receptor gene polymorphisms in relation to vitamin D related disease states. J Steroid Biochem Mol Biol 89–90:187–193
36. Valdivielso JM, Fernandez E (2006) Vitamin D receptor polymorphisms and diseases. Clin Chim Acta 371:1–12
37. VanAmerongen B, Dijkstra C, Lips P et al (2004) Multiple sclerosis and vitamin D: an update. Eur J Clin Nutr 58:1095–1109
38. Wang Y, Marling SJ, Zhu JG et al (2012) Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor. Proc Natl Acad Sci U S A 109:8501–8504