Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients

Neurology

Volumn 54, Issue 3, 2000, Pages 729-732

  Steckley, J L ^a   Dyment, D A ^a   Sadovnick, A D ^c   Risch, N ^d   Hayes, C ^e   Ebers, George C ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d STANFORD UNIVERSITY   (United States)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

MS; Vitamin D

Indexed keywords

COLECALCIFEROL RECEPTOR; UNCLASSIFIED DRUG; VITAMIN D BINDING PROTEIN; VITAMIN D RECEPTOR;

ARTICLE; CANADA; CHROMOSOME 12Q; GENE LOCUS; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 0034620555     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.54.3.729     Document Type: Article

References (8)

1. Sadovnick AD, Ebers GC. Genetics of multiple sclerosis. Mult Scler 1995;13:99-118.
2. Goldberg P. Multiple sclerosis: vitamin D and calcium as environmental determinants of prevalence (a viewpoint). Part 2: Biochemical and genetic factors. Int J Environ Studies 1974;6:19-27.
3. Nieves J, Cosman F, Hebert J, Shen V, Lindsay R. High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis. Neurology 1994;44:1687-1692.
4. Cantorna MT, Hayes CE, DeLuca HF. 1,25-Didydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci 1996;93: 7861-7864.
5. Hayes CE, Cantorna MT, DeLuca HF. Vitamin D and multiple sclerosis. Proc Soc Exp Biol Med 1997;216:21-27.
6. Ebers GC, Sadovnick AD, Risch NJ, et al. A genetic basis for familial aggregation in multiple sclerosis. Nature 1995;377: 150-151.
7. Arnason A, Jensson O, Skaftadottir I, Birgisdottir B, Gudmundsson G, Johannesson G. HLA types, GC protein and other genetic markers in multiple sclerosis and two other neurological diseases in Iceland. Acta Neurol Scand 1980;62(suppl 78): 39-40. Abstract.
8. The marker position on the chromosome 12 genetic map was identified at the Whitehead Institute for Biomedical Research website (http://carbon.wi.mit.edu:8000/cgi-bin/contig/sts_info/).