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1
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84870853780
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Treatment of tobacco dependence in people with mental health and addictive disorders
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PID: 22821177
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Mackowick KM, Lynch MJ, Weinberger AH, George TP. Treatment of tobacco dependence in people with mental health and addictive disorders. Curr Psychiatry Rep. 2012;14(5):478–85.
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Curr Psychiatry Rep
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Mackowick, K.M.1
Lynch, M.J.2
Weinberger, A.H.3
George, T.P.4
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2
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0033739654
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Smoking and mental illness: a population-based prevalence study
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PID: 11086367, COI: 1:STN:280:DC%2BD3M%2FktlGiuw%3D%3D
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Lasser K, Boyd JW, Woolhandler S, Himmelstein DU, McCormick D, Bor DH. Smoking and mental illness: a population-based prevalence study. JAMA. 2000;284(20):2606–10.
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JAMA
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Lasser, K.1
Boyd, J.W.2
Woolhandler, S.3
Himmelstein, D.U.4
McCormick, D.5
Bor, D.H.6
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3
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0031024436
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The self-medication hypothesis of substance use disorders: a reconsideration and recent applications
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PID: 9385000, COI: 1:STN:280:DyaK1c%2Fjs12hsQ%3D%3D
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Khantzian EJ. The self-medication hypothesis of substance use disorders: a reconsideration and recent applications. Harv Rev Psychiatry. 1997;4(5):231–44.
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Harv Rev Psychiatry
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Khantzian, E.J.1
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4
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0035878562
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A neurobiological basis for substance abuse comorbidity in schizophrenia
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PID: 11526998, COI: 1:STN:280:DC%2BD3MvosVOjtA%3D%3D
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Chambers RA, Krystal JH, Self DW. A neurobiological basis for substance abuse comorbidity in schizophrenia. Biol Psychiatry. 2001;50(2):71–83.
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Biol Psychiatry
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Chambers, R.A.1
Krystal, J.H.2
Self, D.W.3
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5
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17744375473
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Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia: involvement of nicotinic receptor mechanisms
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PID: 15939842
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Sacco KA, Termine A, Seyal A, et al. Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia: involvement of nicotinic receptor mechanisms. Arch Gen Psychiatry. 2005;62(6):649–59.
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Arch Gen Psychiatry
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Sacco, K.A.1
Termine, A.2
Seyal, A.3
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6
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84859642317
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Nicotine differentially modulates antisaccade performance in healthy male non-smoking volunteers stratified for low and high accuracy
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COI: 1:CAS:528:DC%2BC3MXhtlyrtrnO
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Petrovsky N, Ettinger U, Quednow BB, et al. Nicotine differentially modulates antisaccade performance in healthy male non-smoking volunteers stratified for low and high accuracy. Psychopharmacology (Berl). 2012;221(1):27–38.
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(2012)
Psychopharmacology (Berl)
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, pp. 27-38
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Petrovsky, N.1
Ettinger, U.2
Quednow, B.B.3
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7
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79960700795
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Neuropsychological performance in patients with schizophrenia and controls as a function of cigarette smoking status
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PID: 21669462
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Wing VC, Bacher I, Sacco KA, George TP. Neuropsychological performance in patients with schizophrenia and controls as a function of cigarette smoking status. Psychiatry Res. 2011;188(3):320–6.
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(2011)
Psychiatry Res
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, pp. 320-326
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Wing, V.C.1
Bacher, I.2
Sacco, K.A.3
George, T.P.4
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8
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76649095277
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Why do patients with schizophrenia smoke?
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PID: 20051860
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Winterer G. Why do patients with schizophrenia smoke? Curr Opin Psychiatry. 2010;23(2):112–9.
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(2010)
Curr Opin Psychiatry
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, pp. 112-119
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Winterer, G.1
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9
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84856576804
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A review of neurobiological vulnerability factors and treatment implications for comorbid tobacco dependence in schizophrenia
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PID: 22129082, COI: 1:CAS:528:DC%2BC38Xks1yit7k%3D
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Wing VC, Wass CE, Soh DW, George TP. A review of neurobiological vulnerability factors and treatment implications for comorbid tobacco dependence in schizophrenia. Ann N Y Acad Sci. 2012;1248:89–106.
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(2012)
Ann N Y Acad Sci
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Wing, V.C.1
Wass, C.E.2
Soh, D.W.3
George, T.P.4
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10
-
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84872417422
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Exploring the relationships between tobacco smoking and schizophrenia in first-degree relatives
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PID: 22939230
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Ferchiou A, Szoke A, Laguerre A, Meary A, Leboyer M, Schurhoff F. Exploring the relationships between tobacco smoking and schizophrenia in first-degree relatives. Psychiatry Res. 2012;200(2–3):674–8.
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(2012)
Psychiatry Res
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Ferchiou, A.1
Szoke, A.2
Laguerre, A.3
Meary, A.4
Leboyer, M.5
Schurhoff, F.6
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11
-
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38149062692
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The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls
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PID: 17443126, COI: 1:CAS:528:DC%2BD1cXmsFSluw%3D%3D
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Barr RS, Culhane MA, Jubelt LE, et al. The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls. Neuropsychopharmacology. 2008;33(3):480–90.
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(2008)
Neuropsychopharmacology
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, pp. 480-490
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Barr, R.S.1
Culhane, M.A.2
Jubelt, L.E.3
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12
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0036791095
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The effects of nicotine on specific eye tracking measures in schizophrenia
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PID: 12372663, COI: 1:CAS:528:DC%2BD38Xns1Sjs7s%3D
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Sherr JD, Myers C, Avila MT, Elliott A, Blaxton TA, Thaker GK. The effects of nicotine on specific eye tracking measures in schizophrenia. Biol Psychiatry. 2002;52(7):721–8.
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(2002)
Biol Psychiatry
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Sherr, J.D.1
Myers, C.2
Avila, M.T.3
Elliott, A.4
Blaxton, T.A.5
Thaker, G.K.6
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13
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62649112887
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Endophenotypes in schizophrenia: a selective review
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PID: 19223268
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Allen AJ, Griss ME, Folley BS, Hawkins KA, Pearlson GD. Endophenotypes in schizophrenia: a selective review. Schizophr Res. 2009;109(1–3):24–37.
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(2009)
Schizophr Res
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, pp. 24-37
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Allen, A.J.1
Griss, M.E.2
Folley, B.S.3
Hawkins, K.A.4
Pearlson, G.D.5
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14
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0038823525
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The endophenotype concept in psychiatry: etymology and strategic intentions
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PID: 12668349
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Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry. 2003;160(4):636–45.
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(2003)
Am J Psychiatry
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, pp. 636-645
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Gottesman, I.I.1
Gould, T.D.2
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16
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1642487135
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Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study
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PID: 14754781
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Tregellas JR, Tanabe JL, Miller DE, Ross RG, Olincy A, Freedman R. Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study. Am J Psychiatry. 2004;161(2):315–21.
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(2004)
Am J Psychiatry
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Tregellas, J.R.1
Tanabe, J.L.2
Miller, D.E.3
Ross, R.G.4
Olincy, A.5
Freedman, R.6
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17
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0029085870
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Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
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PID: 7548469, COI: 1:CAS:528:DyaK2MXnt12mu7c%3D
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Freedman R, Hall M, Adler LE, Leonard S. Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol Psychiatry. 1995;38(1):22–33.
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(1995)
Biol Psychiatry
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Freedman, R.1
Hall, M.2
Adler, L.E.3
Leonard, S.4
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18
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0037465931
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Differential effects of cigarette smoking on performance of a smooth pursuit and a saccadic eye movement task in schizophrenia
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PID: 12686365
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Olincy A, Johnson LL, Ross RG. Differential effects of cigarette smoking on performance of a smooth pursuit and a saccadic eye movement task in schizophrenia. Psychiatry Res. 2003;117(3):223–36.
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(2003)
Psychiatry Res
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, pp. 223-236
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Olincy, A.1
Johnson, L.L.2
Ross, R.G.3
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19
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33748799154
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Review of clinical correlates of P50 sensory gating abnormalities in patients with schizophrenia
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PID: 16469942
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Potter D, Summerfelt A, Gold J, Buchanan RW. Review of clinical correlates of P50 sensory gating abnormalities in patients with schizophrenia. Schizophr Bull. 2006;32(4):692–700.
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(2006)
Schizophr Bull
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Potter, D.1
Summerfelt, A.2
Gold, J.3
Buchanan, R.W.4
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20
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79960699839
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Differential sensory gating functions between smokers and non-smokers among drug-naive first episode schizophrenic patients
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PID: 21216472
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Chen XS, Li CB, Smith RC, Xiao ZP, Wang JJ. Differential sensory gating functions between smokers and non-smokers among drug-naive first episode schizophrenic patients. Psychiatry Res. 2011;188(3):327–33.
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Psychiatry Res
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, pp. 327-333
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Chen, X.S.1
Li, C.B.2
Smith, R.C.3
Xiao, Z.P.4
Wang, J.J.5
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21
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84899711904
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Differences in P50 and prepulse inhibition of the startle reflex between male smokers and non-smokers with first episode schizophrenia without medical treatment
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Song L, Chen X, Chen M, et al. Differences in P50 and prepulse inhibition of the startle reflex between male smokers and non-smokers with first episode schizophrenia without medical treatment. Chin Med J (Engl). 2014;127(9):1651–5.
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Chin Med J (Engl)
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Song, L.1
Chen, X.2
Chen, M.3
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22
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0026472046
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Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics
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PID: 1450287, COI: 1:STN:280:DyaK3s%2FotFKitg%3D%3D
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Adler LE, Hoffer LJ, Griffith J, Waldo MC, Freedman R. Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics. Biol Psychiatry. 1992;32(7):607–16.
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(1992)
Biol Psychiatry
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Adler, L.E.1
Hoffer, L.J.2
Griffith, J.3
Waldo, M.C.4
Freedman, R.5
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23
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0027380988
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Normalization of auditory physiology by cigarette smoking in schizophrenic patients
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PID: 8238642, COI: 1:STN:280:DyaK2c%2FlslWitA%3D%3D
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Adler LE, Hoffer LD, Wiser A, Freedman R. Normalization of auditory physiology by cigarette smoking in schizophrenic patients. Am J Psychiatry. 1993;150(12):1856–61.
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(1993)
Am J Psychiatry
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Adler, L.E.1
Hoffer, L.D.2
Wiser, A.3
Freedman, R.4
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24
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79953200925
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Differential effects of nicotine on P50 amplitude, its gating, and their neural sources in low and high suppressors
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PID: 20643194, COI: 1:CAS:528:DC%2BC3cXhtFGjurrE
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Knott VJ, Fisher DJ, Millar AM. Differential effects of nicotine on P50 amplitude, its gating, and their neural sources in low and high suppressors. Neuroscience. 2010;170(3):816–26.
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Neuroscience
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Knott, V.J.1
Fisher, D.J.2
Millar, A.M.3
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25
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0027087246
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Startle gating deficits occur across prepulse intensities in schizophrenic patients
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PID: 1467378, COI: 1:STN:280:DyaK3s7gsVehtQ%3D%3D
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Grillon C, Ameli R, Charney DS, Krystal J, Braff D. Startle gating deficits occur across prepulse intensities in schizophrenic patients. Biol Psychiatry. 1992;32(10):939–43.
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Biol Psychiatry
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Grillon, C.1
Ameli, R.2
Charney, D.S.3
Krystal, J.4
Braff, D.5
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26
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0034176757
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Impaired prepulse inhibition of acoustic startle in schizophrenia
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PID: 10745060, COI: 1:STN:280:DC%2BD3c3htFWqtA%3D%3D
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Parwani A, Duncan EJ, Bartlett E, et al. Impaired prepulse inhibition of acoustic startle in schizophrenia. Biol Psychiatry. 2000;47(7):662–9.
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Biol Psychiatry
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Parwani, A.1
Duncan, E.J.2
Bartlett, E.3
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27
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0034891977
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Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies
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COI: 1:CAS:528:DC%2BD3MXmtlCqtbY%3D
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Braff DL, Geyer MA, Swerdlow NR. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl). 2001;156(2–3):234–58.
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Psychopharmacology (Berl)
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Braff, D.L.1
Geyer, M.A.2
Swerdlow, N.R.3
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28
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67349247397
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Prepulse inhibition deficits in schizophrenia are modified by smoking status
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PID: 19423298, This is an important study showing thatI levels smokers with schizophrenia are similar to healthy smokers, and significantly better than non-smokers with schizophrenia. These results suggest thatI may be modulated by nicotine schizophrenia
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Woznica AA, Sacco KA, George TP. Prepulse inhibition deficits in schizophrenia are modified by smoking status. Schizophr Res. 2009;112(1–3):86–90. This is an important study showing that PPI levels in smokers with schizophrenia are similar to healthy smokers, and significantly better than non-smokers with schizophrenia. These results suggest that PPI may be modulated by nicotine in schizophrenia.
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(2009)
Schizophr Res
, vol.112
, Issue.1-3
, pp. 86-90
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Woznica, A.A.1
Sacco, K.A.2
George, T.P.3
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29
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69849103367
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Correlation of prepulse inhibition and Wisconsin Card Sorting Test in schizophrenia and controls: effects of smoking status
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PID: 19656658
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Rabin RA, Sacco KA, George TP. Correlation of prepulse inhibition and Wisconsin Card Sorting Test in schizophrenia and controls: effects of smoking status. Schizophr Res. 2009;114(1–3):91–7.
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Schizophr Res
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, pp. 91-97
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Rabin, R.A.1
Sacco, K.A.2
George, T.P.3
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30
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33749071175
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A preliminary study of the effects of cigarette smoking on prepulse inhibition in schizophrenia: involvement of nicotinic receptor mechanisms
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PID: 16854565
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George TP, Termine A, Sacco KA, et al. A preliminary study of the effects of cigarette smoking on prepulse inhibition in schizophrenia: involvement of nicotinic receptor mechanisms. Schizophr Res. 2006;87(1–3):307–15.
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Schizophr Res
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, pp. 307-315
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George, T.P.1
Termine, A.2
Sacco, K.A.3
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31
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0022818151
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Dementia and working memory
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PID: 3809575, COI: 1:STN:280:DyaL2s7hvFWjsw%3D%3D
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Baddeley A, Logie R, Bressi S, Della Sala S, Spinnler H. Dementia and working memory. Q J Exp Psychol A. 1986;38(4):603–18.
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Q J Exp Psychol A
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Baddeley, A.1
Logie, R.2
Bressi, S.3
Della Sala, S.4
Spinnler, H.5
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32
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28544436939
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Working memory impairments in schizophrenia: a meta-analysis
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PID: 16351383
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Lee J, Park S. Working memory impairments in schizophrenia: a meta-analysis. J Abnorm Psychol. 2005;114(4):599–611.
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J Abnorm Psychol
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Lee, J.1
Park, S.2
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33
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0037044009
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Spatial working memory deficits in schizophrenia patients and their first degree relatives from Palau, Micronesia
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PID: 12210274
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Myles-Worsley M, Park S. Spatial working memory deficits in schizophrenia patients and their first degree relatives from Palau, Micronesia. Am J Med Genet. 2002;114(6):609–15.
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Am J Med Genet
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Myles-Worsley, M.1
Park, S.2
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34
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0036149160
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Effects of smoking abstinence on visuospatial working memory function in schizophrenia
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PID: 11751034
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George TP, Vessicchio JC, Termine A, et al. Effects of smoking abstinence on visuospatial working memory function in schizophrenia. Neuropsychopharmacology. 2002;26(1):75–85.
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Neuropsychopharmacology
, vol.26
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, pp. 75-85
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George, T.P.1
Vessicchio, J.C.2
Termine, A.3
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35
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0029943635
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Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs
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PID: 8717040, COI: 1:CAS:528:DyaK28XksVWhur8%3D
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Pontieri FE, Tanda G, Orzi F, Di Chiara G. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature. 1996;382(6588):255–7.
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Nature
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Pontieri, F.E.1
Tanda, G.2
Orzi, F.3
Di Chiara, G.4
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36
-
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84861838749
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A randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of varenicline for smoking cessation in patients with schizophrenia or schizoaffective disorder
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PID: 22697191, COI: 1:CAS:528:DC%2BC38XhtVCls7zK
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Williams JM, Anthenelli RM, Morris CD, et al. A randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of varenicline for smoking cessation in patients with schizophrenia or schizoaffective disorder. J Clin Psychiatry. 2012;73(5):654–60.
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J Clin Psychiatry
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Williams, J.M.1
Anthenelli, R.M.2
Morris, C.D.3
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37
-
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84891929233
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Maintenance treatment with varenicline for smoking cessation in patients with schizophrenia and bipolar disorder: a randomized clinical trial
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PID: 24399553, COI: 1:CAS:528:DC%2BC2cXitFKis70%3D, This maintenance trial was one of the first studies to look at the effect of varenicline on prolonged abstinence smokers with serious mental illness after initial successful abstinence. Varenicline treatment significantly improved and lengthened abstinence without worsening psychiatric symptoms, suggesting a potential benefit of varencline for both smoking cessation and cognition
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Evins AE, Cather C, Pratt SA, et al. Maintenance treatment with varenicline for smoking cessation in patients with schizophrenia and bipolar disorder: a randomized clinical trial. JAMA. 2014;311(2):145–54. This maintenance trial was one of the first studies to look at the effect of varenicline on prolonged abstinence in smokers with serious mental illness after initial successful abstinence. Varenicline treatment significantly improved and lengthened abstinence without worsening psychiatric symptoms, suggesting a potential benefit of varencline for both smoking cessation and cognition.
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(2014)
JAMA
, vol.311
, Issue.2
, pp. 145-154
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Evins, A.E.1
Cather, C.2
Pratt, S.A.3
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38
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64749107050
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Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder
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PID: 19251401
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Smith RC, Lindenmayer JP, Davis JM, et al. Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder. Schizophr Res. 2009;110(1–3):149–55.
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(2009)
Schizophr Res
, vol.110
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, pp. 149-155
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Smith, R.C.1
Lindenmayer, J.P.2
Davis, J.M.3
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39
-
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83055160773
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Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder
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PID: 21810630, COI: 1:CAS:528:DC%2BC38Xns1SitQ%3D%3D, This double-blind, parallel, randomized, placebo-controlled study examined the effects of varenicline on multiple measures of cognition a large sample of both smokers and non-smokers with schizophrenia. Varenicline significantly reduced the P50 response nonsmokers after long-term treatment, but had no effect on working memory, suggesting altered pathophysiology smokers with schizophrenia compared with nonsmokers
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Hong LE, Thaker GK, McMahon RP, et al. Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder. Arch Gen Psychiatry. 2011;68(12):1195–206. This double-blind, parallel, randomized, placebo-controlled study examined the effects of varenicline on multiple measures of cognition in a large sample of both smokers and non-smokers with schizophrenia. Varenicline significantly reduced the P50 response in nonsmokers after long-term treatment, but had no effect on working memory, suggesting altered pathophysiology in smokers with schizophrenia compared with nonsmokers.
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(2011)
Arch Gen Psychiatry
, vol.68
, Issue.12
, pp. 1195-1206
-
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Hong, L.E.1
Thaker, G.K.2
McMahon, R.P.3
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40
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84881231540
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Varenicline modulates spatial working memory deficits in smokers with schizophrenia
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PID: 23849883, This study used a 3-day paradigm of varenicline (0.0, 1.0, or 2.0 mg/day x 3 days) to evaluate its effects on cognitive performance. Varenicline was shown to attenuate abstinence-related cognitive deficits schizophrenia, suggesting the role of α4β2 nAChRs the pathophysiology of comorbid tobacco use patients with schizophrenia
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Wing VC, Wass CE, Bacher I, Rabin RA, George TP. Varenicline modulates spatial working memory deficits in smokers with schizophrenia. Schizophr Res. 2013;149(1–3):190–1. This study used a 3-day paradigm of varenicline (0.0, 1.0, or 2.0 mg/day x 3 days) to evaluate its effects on cognitive performance. Varenicline was shown to attenuate abstinence-related cognitive deficits in schizophrenia, suggesting the role of α4β2 nAChRs in the pathophysiology of comorbid tobacco use in patients with schizophrenia.
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(2013)
Schizophr Res
, vol.149
, Issue.1-3
, pp. 190-191
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Wing, V.C.1
Wass, C.E.2
Bacher, I.3
Rabin, R.A.4
George, T.P.5
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41
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33744911665
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Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia
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