A test of the cognitive self-medication hypothesis of tobacco smoking in schizophrenia

Biological Psychiatry

Volumn 74, Issue 6, 2013, Pages 436-443

  Hahn, Britta ^a   Harvey, Alexander N ^a   Concheiro Guisan, Marta ^b   Huestis, Marilyn A ^b   Holcomb, Henry H ^a   Gold, James M ^a  

^a MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Cognitive deficits; nicotine; schizophrenia; self medication; smoking; withdrawal

Indexed keywords

NICOTINE PATCH; PLACEBO;

ABSTINENCE; ADULT; ARTICLE; ATTENTION; CLINICAL ARTICLE; COGNITIVE SELF MEDICATION HYPOTHESIS; FEMALE; HUMAN; HYPOTHESIS; MALE; PARANOID SCHIZOPHRENIA; PREDICTION; PRIORITY JOURNAL; QUESTIONNAIRE; REACTION TIME; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SELF MEDICATION; SELF REPORT; SMOKING; SMOKING CESSATION; TASK PERFORMANCE; TOBACCO DEPENDENCE;

EID: 84882660548     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.03.017     Document Type: Article

References (67)

1. G.W. Dalack, D.J. Healy, and J.H. Meador-Woodruff Nicotine dependence in schizophrenia: Clinical phenomena and laboratory findings Am J Psychiatry 155 1998 1490 1501
2. K. Lasser, J.W. Boyd, S. Woolhandler, D.U. Himmelstein, D. McCormick, and D.H. Bor Smoking and mental illness: A population-based prevalence study JAMA 284 2000 2606 2610
3. J. de Leon, and F.J. Diaz A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors Schizophr Res 76 2005 135 157
4. J.M. Williams, K.K. Gandhi, S.E. Lu, S. Kumar, M.L. Steinberg, and B. Cottler Shorter interpuff interval is associated with higher nicotine intake in smokers with schizophrenia Drug Alcohol Depend 118 2011 313 319
5. M.S. D'Souza, and A. Markou Schizophrenia and tobacco smoking comorbidity: nAChR agonists in the treatment of schizophrenia-associated cognitive deficits Neuropharmacology 62 2012 1564 1573
6. M.F. Green What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 153 1996 321 330
7. M.F. Green, R.S. Kern, and R.K. Heaton Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for MATRICS Schizophr Res 72 2004 41 51
8. L. Depatie, G.A. O'Driscoll, A.L. Holahan, V. Atkinson, J.X. Thavundayil, and N.N. Kin Nicotine and behavioral markers of risk for schizophrenia: A double-blind, placebo-controlled, cross-over study Neuropsychopharmacology 27 2002 1056 1070
9. R.C. Smith, A. Singh, M. Infante, A. Khandat, and A. Kloos Effects of cigarette smoking and nicotine nasal spray on psychiatric symptoms and cognition in schizophrenia Neuropsychopharmacology 27 2002 479 497
10. R.C. Smith, J. Warner-Cohen, M. Matute, E. Butler, E. Kelly, and S. Vaidhyanathaswamy Effects of nicotine nasal spray on cognitive function in schizophrenia Neuropsychopharmacology 31 2006 637 643
11. J.G. Harris, S. Kongs, D. Allensworth, L. Martin, J. Tregellas, and B. Sullivan Effects of nicotine on cognitive deficits in schizophrenia Neuropsychopharmacology 29 2004 1378 1385
12. A.L. Larrison-Faucher, A.A. Matorin, and A.B. Sereno Nicotine reduces antisaccade errors in task impaired schizophrenic subjects Prog Neuropsychopharmacol Biol Psychiatry 28 2004 505 516
13. C.S. Myers, O. Robles, A.N. Kakoyannis, J.D. Sherr, M.T. Avila, and T.A. Blaxton Nicotine improves delayed recognition in schizophrenic patients Psychopharmacology 174 2004 334 340
14. R.S. Barr, M.A. Culhane, L.E. Jubelt, R.S. Mufti, M.A. Dyer, and A.P. Weiss The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls Neuropsychopharmacology 33 2008 480 490
15. L.E. Jubelt, R.S. Barr, D.C. Goff, T. Logvinenko, A.P. Weiss, and A.E. Evins Effects of transdermal nicotine on episodic memory in non-smokers with and without schizophrenia Psychopharmacology 199 2008 89 98
16. C.G. AhnAllen, P.G. Nestor, M.E. Shenton, R.W. McCarley, and M.A. Niznikiewicz Early nicotine withdrawal and transdermal nicotine effects on neurocognitive performance in schizophrenia Schizophr Res 100 2008 261 269
17. R. Freedman, A. Olincy, R.W. Buchanan, J.G. Harris, J.M. Gold, and L. Johnson Initial phase 2 trial of a nicotinic agonist in schizophrenia Am J Psychiatry 165 2008 1040 1047
18. A. Olincy, J.G. Harris, L.L. Johnson, V. Pender, S. Kongs, and D. Allensworth Proof-of-concept trial of an alpha 7 nicotinic agonist in schizophrenia Arch Gen Psychiatry 63 2006 630 638
19. A.A. Woznica, K.A. Sacco, and T.P. George Prepulse inhibition deficits in schizophrenia are modified by smoking status Schizophr Res 112 2009 86 90
20. T.P. George, J.C. Vessicchio, A. Termine, D.M. Sahady, C.A. Head, and W.T. Pepper Effects of smoking abstinence on visuospatial working memory function in schizophrenia Neuropsychopharmacology 26 2002 75 85
21. K.A. Sacco, A. Termine, A. Seyal, M.M. Dudas, J.C. Vessicchio, and S. Krishnan-Sarin Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia: Involvement of nicotinic receptor mechanisms Arch Gen Psychiatry 62 2005 649 659
22. S.J. Heishman, B.A. Kleykamp, and E.G. Singleton Meta-analysis of the acute effects of nicotine and smoking on human performance Psychopharmacology 210 2010 453 469
23. B. Hahn, C.G.V. Sharples, S. Wonnacott, M. Shoaib, and P. Stolerman Attentional effects of nicotinic agonists in rats Neuropharmacology 44 2003 1054 1067
24. J.W. Kenney, and T.J. Gould Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine Mol Neurobiol 38 2008 101 121
25. I.P. Stolerman, N.R. Mirza, and M. Shoaib Nicotine psychopharmacology: Addiction, cognition and neuroadaptation Med Res Rev 15 1995 47 72
26. P.A. Newhouse, A. Potter, and A. Singh Effects of nicotinic stimulation on cognitive performance Curr Opin Pharmacol 4 2004 36 46
27. B. Hahn, B.M. Robinson, S.T. Kaiser, A.N. Harvey, V.M. Beck, and C.J. Leonard Failure of schizophrenia patients to overcome salient distractors during working memory encoding Biol Psychiatry 68 2010 603 609
28. T.F. Oltmanns, and J.M. Neale Schizophrenic performance when distractors are present: Attentional deficit or differential task difficulty? J Abnorm Psychol 84 1975 205 209
29. S.J. Luck, and J.M. Gold The construct of attention in schizophrenia Biol Psychiatry 64 2008 34 39
30. B. Hahn, B.M. Robinson, A.N. Harvey, S.T. Kaiser, C.J. Leonard, and S.J. Luck Visuospatial attention in schizophrenia: Deficits in broad monitoring J Abnorm Psychol 121 2012 119 128
31. A. Elahipanah, B.K. Christensen, and E.M. Reingold Visual search performance among persons with schizophrenia as a function of target eccentricity Neuropsychology 24 2010 192 198
32. C.E. Adams, and K.E. Stevens Evidence for a role of nicotinic acetylcholine receptors in schizophrenia Front Biosci 12 2007 4755 4772
33. R. Freedman, H. Coon, M. Myles-Worsley, A. Orr-Urtreger, A. Olincy, and A. Davis Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus Proc Natl Acad Sci U S A 94 1997 587 592
34. S. Leonard, J. Gault, J. Hopkins, J. Logel, R. Vianzon, and M. Short Association of promoter variants in the alpha 7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia Arch Gen Psychiatry 59 2002 1085 1096
35. L.F. Martin, W.R. Kem, and R. Freedman Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia Psychopharmacology 174 2004 54 64
36. V.C. Wing, C.E. Wass, D.W. Soh, and T.P. George A review of neurobiological vulnerability factors and treatment implications for comorbid tobacco dependence in schizophrenia Addict Rev 1248 2012 89 106
37. N. Petrovsky, B.B. Quednow, U. Ettinger, A. Schmechtig, R. Mossner, and D.A. Collier Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers Neuropsychopharmacology 35 2010 1429 1439
38. A. Olincy, L.L. Johnson, and R.G. Ross Differential effects of cigarette smoking on performance of a smooth pursuit and a saccadic eye movement task in schizophrenia Psychiatry Res 117 2003 223 236
39. T.P. George, A. Termine, K.A. Sacco, T.M. Allen, E. Reutenauer, and J.C. Vessicchio A preliminary study of the effects of cigarette smoking on prepulse inhibition in schizophrenia: Involvement of nicotinic receptor mechanisms Schizophr Res 87 2006 307 315
40. D. Ziedonis, B. Hitsman, J. Beckham, M. Zvolensky, L. Adler, and J. Audrain-McGovern Tobacco use and cessation in psychiatric disorders: National Institute of Mental Health report Nicotine Tob Res 10 2008 1691 1715
41. C.H. Hennekens Increasing global burden of cardiovascular disease in general populations and patients with schizophrenia J Clin Psychiatry 68 2007 4 7
42. G. Shanmugam, S. Bhutani, D.A. Khan, and E.S. Brown Psychiatric considerations in pulmonary disease Psychiatr Clin North Am 30 2007 761 780
43. S. Himelhoch, and G. Daumit To whom do psychiatrists offer smoking-cessation counseling? Am J Psychiatry 160 2003 2228 2230
44. I.D. Montoya, D.M. Herbeck, D.S. Svikis, and H.A. Pincus Identification and treatment of patients with nicotine problems in routine clinical psychiatry practice Am J Addict 14 2005 441 454
45. S.A. Duffy, A.M. Kilbourne, K.L. Austin, G.W. Dalack, E.M. Woltmann, and J. Waxmonsky Risk of smoking and receipt of cessation services among veterans with mental disorders Psychiatr Serv 63 2012 325 332
46. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 4 ed. 2000 American Psychiatric Association Washington, DC
47. D. Wechsler Wechsler Abbreviated Scale of Intelligence (WASI) 1999 The Psychological Corporation San Antonio, Texas
48. C.D. Spielberger, R.L. Gorssuch, P.R. Lushene, P.R. Vagg, and G.A. Jacobs Manual for the State-Trait Anxiety Inventory 1983 Consulting Psychologists Press Palo Alto, California
49. T.F. Heatherton, L.T. Kozlowski, R.C. Frecker, and K.O. Fagerström The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire Br J Addict 86 1991 1119 1127
50. J.R. Hughes Tobacco withdrawal in self-quitters J Consult Clin Psychol 60 1992 689 697
51. A.C. Parrott, N.J. Garnham, K. Wesnes, and C. Pincock Cigarette smoking and abstinence: Comparative effects upon cognitive task performance and mood state over 24 hours Human Psychopharmacology 11 1996 391 400
52. B. Hahn, T.J. Ross, and E.A. Stein Neuroanatomical dissociation between bottom-up and top-down processes of visuospatial selective attention Neuroimage 32 2006 842 853
53. M.L. Steinberg, J.M. Williams, H.R. Steinberg, J.A. Krejci, and D.M. Ziedonis Applicability of the Fagerstrom test for nicotine dependence in smokers with schizophrenia Addict Behav 30 2005 49 59
54. J.E. Henningfield, and R.M. Keenan Nicotine delivery kinetics and abuse liability J Consult Clin Psychol 61 1993 743 750
55. J.M. Williams, K.K. Gandhi, S.E. Lu, S. Kumar, J.W. Shen, and J. Foulds Higher nicotine levels in schizophrenia compared with controls after smoking a single cigarette Nicotine Tob Res 12 2010 855 859
56. K.J. Palmer, M.M. Buckley, and D. Faulds Transdermal Nicotine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy as an aid to smoking cessation Drugs 44 1992 498 529
57. S.K. Gupta, N.L. Benowitz, P,. Jacob III, C.N. Rolf, and J. Gorsline Bioavailability and absorption kinetics of nicotine following application of a transdermal system Br J Clin Pharmacol 36 1993 221 227
58. R.V. Fant, J.E. Henningfield, S. Shiffman, K.R. Strahs, and D.P. Reitberg A pharmacokinetic crossover study to compare the absorption characteristics of three transdermal nicotine patches Pharmacol Biochem Behav 67 2000 479 482
59. W.P. Horan, J.J. Blanchard, L.A. Clark, and M.F. Green Affective traits in schizophrenia and schizotypy Schizophr Bull 34 2008 856 874
60. B. Hahn, M. Shoaib, and I.P. Stolerman Nicotine-induced enhancement of attention in the five-choice serial reaction time task: The influence of task-demands Psychopharmacology 162 2002 129 137
61. R.A. Chambers, J.H. Krystal, and D.W. Self A neurobiological basis for substance abuse comorbidity in schizophrenia Biol Psychiatry 50 2001 71 83
62. B. Hahn, J.M. Gold, and R.W. Buchanan The potential of nicotinic enhancement of cognitive remediation training in schizophrenia Neuropharmacology 64 2013 185 190
63. G.W. Dalack, L. Becks, E. Hill, O.F. Pomerleau, and J.H. Meador-Woodruff Nicotine withdrawal and psychiatric symptoms in cigarette smokers with schizophrenia Neuropsychopharmacology 21 1999 195 202
64. Weiner E, Ahmed S (2013): Smoking cessation in schizophrenia. Curr Psychiatry Rev 9:164-172
65. T.C. Durazzo, D.J. Meyerhoff, and S. Jo Nixon Chronic cigarette smoking: Implications for neurocognition and brain neurobiology Int J Environ Res Public Health 7 2010 3760 3791
66. D. Cousineau Confidence intervals in within-subject designs: A simpler solution to Loftus and Masson's method Tutorials Quant Methods Psychol 1 2007 42 45
67. R.D. Morey Confidence intervals from normalized data: A correction of Cousineau (2005) Tutorials Quant Methods Psychol 4 2008 61 64