Gastrointestinal Autoimmunity Associated With Loss of Central Tolerance to Enteric α-Defensins

Gastroenterology

Volumn 149, Issue 1, 2015, Pages 139-150

  Dobeš, Jan ^a   Neuwirth, Aleš ^a   Dobešová, Martina ^a   Vobořil, Matouš ^a   Balounová, Jana ^a   Ballek, Ondřej ^a   Lebl, Jan ^b   Meloni, Antonella ^c   Krohn, Kai ^d   Kluger, Nicolas ^d   Ranki, Annamari ^d   Filipp, Dominik ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF CAGLIARI   (Italy)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

DEFA; Intestinal Crypt; Microbiota; Mouse Model

Indexed keywords

ALPHA DEFENSIN; AUTOANTIBODY; AUTOANTIGEN; AUTOIMMUNE REGULATOR PROTEIN; CATHEPSIN S; CHROMOGRANIN A; DEFA5 PROTEIN; DEFA6 PROTEIN; GLUTAMATE DECARBOXYLASE 67; IMMUNOGLOBULIN G ANTIBODY; INSULIN; INTERLEUKIN 17; MESSENGER RNA; MUCIN 6; PROTEASOME; UNCLASSIFIED DRUG; TRANSCRIPTION FACTOR;

ADOLESCENT; ADOPTIVE TRANSFER; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL LOSS; CELL STRUCTURE; CHILD; CLINICAL ARTICLE; COMPARATIVE STUDY; DIARRHEA; DUODENUM BIOPSY; DYSBIOSIS; EPITHELIUM CELL; FECES ANALYSIS; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOBLOTTING; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; LETTER; LYMPH NODE; LYMPHOCYTIC INFILTRATION; MALE; MESENTERY LYMPH NODE; MICROBIOME; MICROSCOPY; MIDDLE AGED; MOUSE; NONHUMAN; PANETH CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; T LYMPHOCYTE; TH17 CELL; THYMOCYTE; WESTERN BLOTTING; YOUNG ADULT; ANIMAL; C57BL MOUSE; COMPLICATION; GENETICS; IMMUNOLOGY; INTESTINE; KNOCKOUT MOUSE; POLYENDOCRINOPATHY;

ADOLESCENT; ADULT; AGED; ALPHA-DEFENSINS; ANIMALS; AUTOIMMUNITY; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INTESTINES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; POLYENDOCRINOPATHIES, AUTOIMMUNE; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 84931412671     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.05.009     Document Type: Article

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