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Volumn 35, Issue 6, 2015, Pages 3147-3154

The story of MCF-7 breast cancer cell line: 40 Years of experience in research

Author keywords

Angiogenesis; Breast cancer; Lymphangiogenesis; MCF 7; Mesenchymal stem cells; Review

Indexed keywords

BETA CATENIN; CHEMOKINE RECEPTOR CXCR4; CLAUDIN; CYTOKERATIN 18; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HERMES ANTIGEN; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; PROTEIN ZO1; SMOOTH MUSCLE ACTIN; UVOMORULIN; VIMENTIN;

EID: 84931342732     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (476)

References (41)
  • 4
    • 84880263301 scopus 로고    scopus 로고
    • Models and Mechanisms of Acquired Antihormone Resistance in Breast Cancer: Significant Clinical Progress Despite Limitations
    • Sweeney EE, Mcdaniel RE, Maximov PY, Fan P and Craig V: Models and Mechanisms of Acquired Antihormone Resistance in Breast Cancer: Significant Clinical Progress Despite Limitations. Horm Mol Biol Clin Investig 9: 143-163, 2013.
    • (2013) Horm Mol Biol Clin Investig , vol.9 , pp. 143-163
    • Sweeney, E.E.1    Mcdaniel, R.E.2    Maximov, P.Y.3    Fan, P.4    Craig, V.5
  • 5
    • 0015762456 scopus 로고
    • A human cell line from a pleural effusion derived from a breast carcinoma
    • Soule HD, Vazguez J, Long A, Albert S and Brennan M: A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 51: 1409-1416, 1973.
    • (1973) J Natl Cancer Inst , vol.51 , pp. 1409-1416
    • Soule, H.D.1    Vazguez, J.2    Long, A.3    Albert, S.4    Brennan, M.5
  • 6
    • 0030802967 scopus 로고    scopus 로고
    • MCF-7: The First Hormone-responsive Breast Cancer Cell Line
    • Levenson AS and Jordan VC: MCF-7: The First Hormone-responsive Breast Cancer Cell Line. Cancer Res 57: 3071-3078, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3071-3078
    • Levenson, A.S.1    Jordan, V.C.2
  • 8
    • 84994656816 scopus 로고    scopus 로고
    • Remarks in Successful Cellular Investigations for Fighting Breast Cancer Using Novel Synthetic Compounds
    • Gunduz M, Gunduz E (eds.). Rijeka, InTech
    • Shirazi FH: Remarks in Successful Cellular Investigations for Fighting Breast Cancer Using Novel Synthetic Compounds. In: Breast Cancer - Focusing Tumor Microenvironment, Stem Cells and Metastasis (Gunduz M, Gunduz E (eds.). Rijeka, InTech, pp. 85-102, 2011.
    • (2011) Breast Cancer - Focusing Tumor Microenvironment, Stem Cells and Metastasis , pp. 85-102
    • Shirazi, F.H.1
  • 11
    • 84858199250 scopus 로고    scopus 로고
    • Mesenchymal stem cell-tumor cell cooperation in breast cancer vasculogenesis
    • Comşa Ş, Ciuculescu F and Raica M: Mesenchymal stem cell-tumor cell cooperation in breast cancer vasculogenesis. Mol Med Rep 5: 1175-1180, 2012.
    • (2012) Mol Med Rep , vol.5 , pp. 1175-1180
    • Comşa, Ş.1    Ciuculescu, F.2    Raica, M.3
  • 12
    • 34248387305 scopus 로고    scopus 로고
    • Stimulation of proliferation of MCF-7 breast cancer cells by a transfected splice variant of growth hormone-releasing hormone receptor
    • Barabutis N, Tsellou E, Schally AV, Kouloheri S, Kalofoutis A and Kiaris H: Stimulation of proliferation of MCF-7 breast cancer cells by a transfected splice variant of growth hormone-releasing hormone receptor. Proc Natl Acad Sci USA 104: 5575-5579, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5575-5579
    • Barabutis, N.1    Tsellou, E.2    Schally, A.V.3    Kouloheri, S.4    Kalofoutis, A.5    Kiaris, H.6
  • 13
    • 84872065517 scopus 로고    scopus 로고
    • Autocrine functions of VEGF in breast tumor cells: Adhesion, survival, migration and invasion
    • Perrot-Applanat M and Di Benedetto M: Autocrine functions of VEGF in breast tumor cells: adhesion, survival, migration and invasion. Cell Adh Migr 6: 547-553, 2012.
    • (2012) Cell Adh Migr , vol.6 , pp. 547-553
    • Perrot-Applanat, M.1    Di Benedetto, M.2
  • 14
    • 0036731988 scopus 로고    scopus 로고
    • Transcriptional Regulation of Vascular Endothelial Growth Factor by Estradiol and Tamoxifen in Breast Cancer Cells: A Complex Interplay between Estrogen Receptors α and β Transcriptional Regulation of Vascular Endothelial Growth Factor by Estradiol and T
    • Buteau-Iozano H, Ancelin M and Lardeux B: Transcriptional Regulation of Vascular Endothelial Growth Factor by Estradiol and Tamoxifen in Breast Cancer Cells: A Complex Interplay between Estrogen Receptors α and β Transcriptional Regulation of Vascular Endothelial Growth Factor by Estradiol and T. Cancer Res 62: 4977-4984, 2002.
    • (2002) Cancer Res , vol.62 , pp. 4977-4984
    • Buteau-Iozano, H.1    Ancelin, M.2    Lardeux, B.3
  • 15
    • 0015898197 scopus 로고
    • Estrogen Receptor in a Human Cell Line (MCF-7) from Breast Carcinoma
    • Brooks SC, Locke ER and Soule HD: Estrogen Receptor in a Human Cell Line (MCF-7) from Breast Carcinoma. J Biol Chem 248: 6251-6253, 1973.
    • (1973) J Biol Chem , vol.248 , pp. 6251-6253
    • Brooks, S.C.1    Locke, E.R.2    Soule, H.D.3
  • 16
    • 2942608091 scopus 로고    scopus 로고
    • 17beta-Estradiol responsiveness of MCF-7 laboratory strains is dependent on an autocrine signal activating the IGF type I receptor
    • Hamelers IHL, Schaik RFMA Van, Sussenbach JS and Steenbergh PH: 17beta-Estradiol responsiveness of MCF-7 laboratory strains is dependent on an autocrine signal activating the IGF type I receptor. Cancer Cell Int 3: 10, 2003.
    • (2003) Cancer Cell Int , vol.3 , pp. 10
    • Hamelers, I.H.L.1    Van Schaik, R.F.M.A.2    Sussenbach, J.S.3    Steenbergh, P.H.4
  • 18
    • 84897848762 scopus 로고    scopus 로고
    • Evidence for the Existence of Triple-Negative Variants in the MCF-7 Breast Cancer Cell Population
    • Leung E, Kim JE, Askarian-amiri M, Finlay GJ and Baguley C: Evidence for the Existence of Triple-Negative Variants in the MCF-7 Breast Cancer Cell Population. Biomed Res Int 2014: 1-7, 2014.
    • (2014) Biomed Res Int , vol.2014 , pp. 1-7
    • Leung, E.1    Kim, J.E.2    Askarian-amiri, M.3    Finlay, G.J.4    Baguley, C.5
  • 20
    • 84891616451 scopus 로고    scopus 로고
    • Selection of a MCF-7 Breast Cancer Cell Subpopulation with High Sensitivity to IL-1β: Characterization of and Correlation between Morphological and Molecular Changes Leading to Increased Invasiveness
    • Pérez-Yépez EA, Ayala-Sumuano J-T, Reveles-Espinoza AM and Meza I: Selection of a MCF-7 Breast Cancer Cell Subpopulation with High Sensitivity to IL-1β: Characterization of and Correlation between Morphological and Molecular Changes Leading to Increased Invasiveness. Int J Breast Cancer 2012: 609148, 2012.
    • (2012) Int J Breast Cancer , pp. 2012
    • Pérez-Yépez, E.A.1    Ayala-Sumuano, J.-T.2    Reveles-Espinoza, A.M.3    Meza, I.4
  • 21
    • 69949141694 scopus 로고    scopus 로고
    • Human mesenchymal stem cells induce E-cadherin degradation in breast carcinoma spheroids by activating ADAM10
    • Dittmer A, Hohlfeld K, Lützkendorf J, Müller LP and Dittmer J: Human mesenchymal stem cells induce E-cadherin degradation in breast carcinoma spheroids by activating ADAM10. Cell Mol life Sci 66: 3053-3065, 2009.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 3053-3065
    • Dittmer, A.1    Hohlfeld, K.2    Lützkendorf, J.3    Müller, L.P.4    Dittmer, J.5
  • 22
    • 0034967344 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: New insights into their synergistic effects
    • Dupont J and Roith D Le: Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects. J Clin Pathol Mol Pathol 54: 149-154, 2001.
    • (2001) J Clin Pathol Mol Pathol , vol.54 , pp. 149-154
    • Dupont, J.1    Le Roith, D.2
  • 24
    • 33646163924 scopus 로고    scopus 로고
    • COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer
    • Timoshenko A V, Chakraborty C, Wagner GF and Lala PK: COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer. Br J Cancer 94: 1154-1163, 2006.
    • (2006) Br J Cancer , vol.94 , pp. 1154-1163
    • Timoshenko, A.V.1    Chakraborty, C.2    Wagner, G.F.3    Lala, P.K.4
  • 25
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
    • Lee T-H, Seng S, Sekine M, Hinton C, Fu Y, Avraham HK and Avraham S: Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med 4: e186, 2007.
    • (2007) PLoS Med , vol.4 , pp. e186
    • Lee, T.-H.1    Seng, S.2    Sekine, M.3    Hinton, C.4    Fu, Y.5    Avraham, H.K.6    Avraham, S.7
  • 26
    • 0043136697 scopus 로고    scopus 로고
    • Overexpression of Vascular Endothelial Growth Factor by MCF-7 Breast Cancer Cells Promotes Estrogen-independent Tumor Growth in Vivo Overexpression of Vascular Endothelial Growth Factor by MCF-7 Breast Cancer Cells Promotes Estrogen-independent Tumor Grow
    • Guo P, Fang Q, Tao H, Schafer CA, Fenton BM, Ding I and Hu B: Overexpression of Vascular Endothelial Growth Factor by MCF-7 Breast Cancer Cells Promotes Estrogen-independent Tumor Growth in Vivo Overexpression of Vascular Endothelial Growth Factor by MCF-7 Breast Cancer Cells Promotes Estrogen-independent Tumor Grow. Cancer Res 63: 4684-4691, 2003.
    • (2003) Cancer Res , vol.63 , pp. 4684-4691
    • Guo, P.1    Fang, Q.2    Tao, H.3    Schafer, C.A.4    Fenton, B.M.5    Ding, I.6    Hu, B.7
  • 27
    • 27644469160 scopus 로고    scopus 로고
    • Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells
    • Garvin S, Nilsson UW and Dabrosin C: Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells. Br J Cancer 93: 1005-1010, 2005.
    • (2005) Br J Cancer , vol.93 , pp. 1005-1010
    • Garvin, S.1    Nilsson, U.W.2    Dabrosin, C.3
  • 28
    • 0028954492 scopus 로고
    • Enhancement of Tumor Growth and Vascular Density by Transfection of Vascular Endothelial Cell Growth Factor Into MCF-7 Human Breast Carcinoma Cells
    • Zhang HT, Craft P, Scott PA, Ziche M, Weich HA, Harris AL and Bicknell R: Enhancement of Tumor Growth and Vascular Density by Transfection of Vascular Endothelial Cell Growth Factor Into MCF-7 Human Breast Carcinoma Cells. J Natl Cancer Inst 87: 213-219, 1995.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 213-219
    • Zhang, H.T.1    Craft, P.2    Scott, P.A.3    Ziche, M.4    Weich, H.A.5    Harris, A.L.6    Bicknell, R.7
  • 29
    • 14944378653 scopus 로고    scopus 로고
    • Effect of estrogen, tamoxifen and epidermal growth factor on the transcriptional regulation of vascular endothelial growth factor in breast cancer cells
    • Lee JE, Chung KW, Han W, Kim SW, Kim SW, Shin HJ, Bae JY and Noh DY: Effect of estrogen, tamoxifen and epidermal growth factor on the transcriptional regulation of vascular endothelial growth factor in breast cancer cells. Anticancer Res 24: 3961-3964, 2004.
    • (2004) Anticancer Res , vol.24 , pp. 3961-3964
    • Lee, J.E.1    Chung, K.W.2    Han, W.3    Kim, S.W.4    Kim, S.W.5    Shin, H.J.6    Bae, J.Y.7    Noh, D.Y.8
  • 30
    • 0032705610 scopus 로고    scopus 로고
    • Vascular endothelial growth factor overproduced by tumour cells acts predominantly as a potent angiogenic factor contributing to malignant progression
    • Aonuma M, Saeki Y, Akimoto T, Nakayama Y, Hattori C, Yoshitake Y, Nishikawa K, Shibuya M and Tanaka NG: Vascular endothelial growth factor overproduced by tumour cells acts predominantly as a potent angiogenic factor contributing to malignant progression. Int J Exp Pathol 80: 271-281, 1999.
    • (1999) Int J Exp Pathol , vol.80 , pp. 271-281
    • Aonuma, M.1    Saeki, Y.2    Akimoto, T.3    Nakayama, Y.4    Hattori, C.5    Yoshitake, Y.6    Nishikawa, K.7    Shibuya, M.8    Tanaka, N.G.9
  • 31
    • 33749457974 scopus 로고    scopus 로고
    • Estrogen receptor positive breast cancer metastasis: Altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes
    • 1
    • Harrell JC1, Dye WW, Allred DC, Jedlicka P, Spoelstra NS, Sartorius CA and Horwitz KB: Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes. Cancer Res 66: 9308-9315, 2006.
    • (2006) Cancer Res , vol.66 , pp. 9308-9315
    • Harrell, J.C.1    Dye, W.W.2    Allred, D.C.3    Jedlicka, P.4    Spoelstra, N.S.5    Sartorius, C.A.6    Horwitz, K.B.7
  • 33
    • 17444388550 scopus 로고    scopus 로고
    • A potential role for vascular endothelial growth factor-D as an autocrine growth factor for human breast carcinoma cells
    • Akahane M, Akahane T, Shah A, Okajima E and Thorgeirsson UP: A potential role for vascular endothelial growth factor-D as an autocrine growth factor for human breast carcinoma cells. Anticancer Res 25: 701-707, 2005.
    • (2005) Anticancer Res , vol.25 , pp. 701-707
    • Akahane, M.1    Akahane, T.2    Shah, A.3    Okajima, E.4    Thorgeirsson, U.P.5
  • 34
    • 4043128107 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor D is associated with hypoxia inducible factor (HIF-1alpha) and the HIF-1alpha target gene DEC1, but not lymph node metastasis in primary human breast carcinomas
    • 1
    • Currie MJ1, Hanrahan V, Gunningham SP, Morrin HR, Frampton C, Han C, Robinson BA and Fox SB: Expression of vascular endothelial growth factor D is associated with hypoxia inducible factor (HIF-1alpha) and the HIF-1alpha target gene DEC1, but not lymph node metastasis in primary human breast carcinomas. J Clin Pathol 57: 829-834, 2004.
    • (2004) J Clin Pathol , vol.57 , pp. 829-834
    • Currie, M.J.1    Hanrahan, V.2    Gunningham, S.P.3    Morrin, H.R.4    Frampton, C.5    Han, C.6    Robinson, B.A.7    Fox, S.B.8
  • 35
    • 0037458645 scopus 로고    scopus 로고
    • Upregulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway
    • Tsai PW, Shiah SG, Lin MT, Wu CW and Kuo ML: Upregulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway. J Biol Chem 278: 5750-5759, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 5750-5759
    • Tsai, P.W.1    Shiah, S.G.2    Lin, M.T.3    Wu, C.W.4    Kuo, M.L.5
  • 38
    • 84886793508 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from breast cancer tissue promote the proliferation and migration of the MCF-7 cell line in vitro
    • Zhang C, Zhai W, Xie Y, Chen Q, Zhu W and Sun X: Mesenchymal stem cells derived from breast cancer tissue promote the proliferation and migration of the MCF-7 cell line in vitro. Oncol Lett 6: 1577-1582, 2013.
    • (2013) Oncol Lett , vol.6 , pp. 1577-1582
    • Zhang, C.1    Zhai, W.2    Xie, Y.3    Chen, Q.4    Zhu, W.5    Sun, X.6
  • 39
    • 84883232383 scopus 로고    scopus 로고
    • Human adipose-derived stem cell adipogenesis induces paracrine regulation of the invasive ability of MCF-7 human breast cancer cells in vitro
    • Zhao Y, Gao J and Lu F: Human adipose-derived stem cell adipogenesis induces paracrine regulation of the invasive ability of MCF-7 human breast cancer cells in vitro. Exp Ther Med 6: 937-942, 2013.
    • (2013) Exp Ther Med , vol.6 , pp. 937-942
    • Zhao, Y.1    Gao, J.2    Lu, F.3
  • 40
    • 84865707754 scopus 로고    scopus 로고
    • MCF7-MSC co-culture assay: Approach to assess the co-operation between MCF-7s and MSCs in tumor-induced angiogenesis
    • Comşa Ş, Ciuculescu F, Henschler R and Raica M: MCF7-MSC co-culture assay: approach to assess the co-operation between MCF-7s and MSCs in tumor-induced angiogenesis. Rom J Morphol Embryol 52: 1071-1076, 2011.
    • (2011) Rom J Morphol Embryol , vol.52 , pp. 1071-1076
    • Comşa, Ş.1    Ciuculescu, F.2    Henschler, R.3    Raica, M.4
  • 41
    • 84871563488 scopus 로고    scopus 로고
    • Inhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs
    • Lian L, Li W, Li ZY, Mao YX, Zhang YT, Zhao YM, Chen K, Duan WM and Tao M: Inhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs. Oncol Lett 5: 675-680, 2013.
    • (2013) Oncol Lett , vol.5 , pp. 675-680
    • Lian, L.1    Li, W.2    Li, Z.Y.3    Mao, Y.X.4    Zhang, Y.T.5    Zhao, Y.M.6    Chen, K.7    Duan, W.M.8    Tao, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.