메뉴 건너뛰기




Volumn 6, Issue 6, 2012, Pages 547-553

Autocrine functions of VEGF in breast tumor cells: Adhesion, survival, migration and invasion

Author keywords

Breast tumor; Tumor cells; VEGF; VEGF receptors; VEGF A

Indexed keywords

NEUROPILIN 1; NEUROPILIN 2; SEMAPHORIN 3A; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

EID: 84872065517     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.23332     Document Type: Review
Times cited : (141)

References (74)
  • 1
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • PMID:9034784
    • Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 1997; 18:4-25; PMID:9034784; http://dx.doi.org/10.1210/er.18. 1.4.
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 2
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • PMID:7584949
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995; 1:27-31; PMID:7584949; http://dx.doi.org/10.1038/nm0195- 27.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 3
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • PMID:1711045
    • Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fiddes JC, et al. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 1991; 266:11947-54; PMID:1711045.
    • (1991) J Biol Chem , vol.266 , pp. 11947-11954
    • Tischer, E.1    Mitchell, R.2    Hartman, T.3    Silva, M.4    Gospodarowicz, D.5    Fiddes, J.C.6
  • 4
    • 0026723142 scopus 로고
    • The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules
    • PMID:1556117
    • Gitay-Goren H, Soker S, Vlodavsky I, Neufeld G. The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules. J Biol Chem 1992; 267:6093-8; PMID:1556117.
    • (1992) J Biol Chem , vol.267 , pp. 6093-6098
    • Gitay-Goren, H.1    Soker, S.2    Vlodavsky, I.3    Neufeld, G.4
  • 5
    • 0027751890 scopus 로고
    • The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
    • PMID:8167412
    • Park JE, Keller GA, Ferrara N. The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol Biol Cell 1993; 4:1317-26; PMID:8167412.
    • (1993) Mol Biol Cell , vol.4 , pp. 1317-1326
    • Park, J.E.1    Keller, G.A.2    Ferrara, N.3
  • 6
    • 0027064888 scopus 로고
    • Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
    • PMID:1464614
    • Houck KA, Leung DW, Rowland AM, Winer J, Ferrara N. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J Biol Chem 1992; 267:26031-7; PMID:1464614.
    • (1992) J Biol Chem , vol.267 , pp. 26031-26037
    • Houck, K.A.1    Leung, D.W.2    Rowland, A.M.3    Winer, J.4    Ferrara, N.5
  • 7
    • 0030976894 scopus 로고    scopus 로고
    • Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect
    • PMID:9148962
    • Plouët J, Moro F, Bertagnolli S, Coldeboeuf N, Mazarguil H, Clamens S, et al. Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect. J Biol Chem 1997; 272:13390-6; PMID:9148962; http://dx.doi.org/10.1074/jbc.272.20. 13390.
    • (1997) J Biol Chem , vol.272 , pp. 13390-13396
    • Plouët, J.1    Moro, F.2    Bertagnolli, S.3    Coldeboeuf, N.4    Mazarguil, H.5    Clamens, S.6
  • 8
    • 22344437713 scopus 로고    scopus 로고
    • Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
    • PMID:15911882
    • Lee S, Jilani SM, Nikolova GV, Carpizo D, Iruela-Arispe ML. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J Cell Biol 2005; 169:681-91; PMID:15911882; http://dx.doi.org/10.1083/jcb.200409115.
    • (2005) J Cell Biol , vol.169 , pp. 681-691
    • Lee, S.1    Jilani, S.M.2    Nikolova, G.V.3    Carpizo, D.4    Iruela-Arispe, M.L.5
  • 9
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • PMID:9872925
    • Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 1999; 13:9-22; PMID:9872925.
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 10
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • PMID:12778165
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003; 9:669-76; PMID:12778165; http://dx.doi.org/10.1038/nm0603-669.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 11
    • 33750842076 scopus 로고    scopus 로고
    • Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis
    • PMID:17002866
    • Shibuya M. Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. J Biochem Mol Biol 2006; 39:469-78; PMID:17002866; http://dx.doi.org/10.5483/BMBRep.2006.39.5.469.
    • (2006) J Biochem Mol Biol , vol.39 , pp. 469-478
    • Shibuya, M.1
  • 12
    • 44649128099 scopus 로고    scopus 로고
    • The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching
    • PMID:18504303
    • Kappas NC, Zeng G, Chappell JC, Kearney JB, Hazarika S, Kallianos KG, et al. The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching. J Cell Biol 2008; 181:847-58; PMID:18504303; http://dx.doi.org/10. 1083/jcb.200709114.
    • (2008) J Cell Biol , vol.181 , pp. 847-858
    • Kappas, N.C.1    Zeng, G.2    Chappell, J.C.3    Kearney, J.B.4    Hazarika, S.5    Kallianos, K.G.6
  • 13
    • 38749149555 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor 189 in breast cancer cells leads to delayed tumor uptake with dilated intratumoral vessels
    • PMID:18079435
    • Hervé M-A, Buteau-Lozano H, Vassy R, Bieche I, Velasco G, Pla M, et al. Overexpression of vascular endothelial growth factor 189 in breast cancer cells leads to delayed tumor uptake with dilated intratumoral vessels. Am J Pathol 2008; 172:167-78; PMID:18079435; http://dx.doi.org/10.2353/ajpath.2008. 070181.
    • (2008) Am J Pathol , vol.172 , pp. 167-178
    • Hervé, M.-A.1    Buteau-Lozano, H.2    Vassy, R.3    Bieche, I.4    Velasco, G.5    Pla, M.6
  • 14
    • 0037197921 scopus 로고    scopus 로고
    • A dynamic shift of VEGF isoforms with a transient and selective progesterone-induced expression of VEGF189 regulates angiogenesis and vascular permeability in human uterus
    • PMID:11972026
    • Ancelin M, Buteau-Lozano H, Meduri G, Osborne-Pellegrin M, Sordello S, Plouët J, et al. A dynamic shift of VEGF isoforms with a transient and selective progesterone-induced expression of VEGF189 regulates angiogenesis and vascular permeability in human uterus. Proc Natl Acad Sci U S A 2002; 99:6023-8; PMID:11972026; http://dx.doi.org/10.1073/pnas.082110999.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6023-6028
    • Ancelin, M.1    Buteau-Lozano, H.2    Meduri, G.3    Osborne-Pellegrin, M.4    Sordello, S.5    Plouët, J.6
  • 15
    • 0037108152 scopus 로고    scopus 로고
    • Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis
    • PMID:12381667
    • Ruhrberg C, Gerhardt H, Golding M, Watson R, Ioannidou S, Fujisawa H, et al. Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes Dev 2002; 16:2684-98; PMID:12381667; http://dx.doi.org/10.1101/gad.242002.
    • (2002) Genes Dev , vol.16 , pp. 2684-2698
    • Ruhrberg, C.1    Gerhardt, H.2    Golding, M.3    Watson, R.4    Ioannidou, S.5    Fujisawa, H.6
  • 16
    • 42049088503 scopus 로고    scopus 로고
    • Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors
    • PMID:18381437
    • Tozer GM, Akerman S, Cross NA, Barber PR, Björndahl MA, Greco O, et al. Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors. Cancer Res 2008; 68:2301-11; PMID:18381437; http://dx.doi.org/10.1158/0008-5472.CAN-07- 2011.
    • (2008) Cancer Res , vol.68 , pp. 2301-2311
    • Tozer, G.M.1    Akerman, S.2    Cross, N.A.3    Barber, P.R.4    Björndahl, M.A.5    Greco, O.6
  • 17
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • PMID:9529250
    • Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 1998; 92:735-45; PMID:9529250; http://dx.doi.org/10.1016/S0092-8674(00)81402-6.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 18
    • 0034925637 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells
    • PMID:11306513
    • Price DJ, Miralem T, Jiang S, Steinberg R, Avraham H. Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells. Cell Growth Differ 2001; 12:129-35; PMID:11306513.
    • (2001) Cell Growth Differ , vol.12 , pp. 129-135
    • Price, D.J.1    Miralem, T.2    Jiang, S.3    Steinberg, R.4    Avraham, H.5
  • 19
    • 28744454292 scopus 로고    scopus 로고
    • Autocrine vascular endothelial growth factor signalling in breast cancer. Evidence from cell lines and primary breast cancer cultures in vitro
    • PMID:16328160
    • Weigand M, Hantel P, Kreienberg R, Waltenberger J. Autocrine vascular endothelial growth factor signalling in breast cancer. Evidence from cell lines and primary breast cancer cultures in vitro. Angiogenesis 2005; 8:197-204; PMID:16328160; http://dx.doi.org/10.1007/s10456-005-9010-0.
    • (2005) Angiogenesis , vol.8 , pp. 197-204
    • Weigand, M.1    Hantel, P.2    Kreienberg, R.3    Waltenberger, J.4
  • 20
    • 0035422178 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells
    • PMID:11479209
    • Bachelder RE, Crago A, Chung J, Wendt MA, Shaw LM, Robinson G, et al. Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells. Cancer Res 2001; 61:5736-40; PMID:11479209.
    • (2001) Cancer Res , vol.61 , pp. 5736-5740
    • Bachelder, R.E.1    Crago, A.2    Chung, J.3    Wendt, M.A.4    Shaw, L.M.5    Robinson, G.6
  • 21
    • 0035817716 scopus 로고    scopus 로고
    • VEGF(165) requires extracellular matrix components to induce mitogenic effects and migratory response in breast cancer cells
    • PMID:11571649
    • Miralem T, Steinberg R, Price D, Avraham H. VEGF(165) requires extracellular matrix components to induce mitogenic effects and migratory response in breast cancer cells. Oncogene 2001; 20:5511-24; PMID:11571649; http://dx.doi.org/10.1038/sj.onc.1204753.
    • (2001) Oncogene , vol.20 , pp. 5511-5524
    • Miralem, T.1    Steinberg, R.2    Price, D.3    Avraham, H.4
  • 22
    • 73349092792 scopus 로고    scopus 로고
    • Neuropilin-2 expression in breast cancer: Correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression
    • PMID:19580679
    • Yasuoka H, Kodama R, Tsujimoto M, Yoshidome K, Akamatsu H, Nakahara M, et al. Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression. BMC Cancer 2009; 9:220; PMID:19580679; http://dx.doi.org/10.1186/1471-2407-9-220.
    • (2009) BMC Cancer , vol.9 , pp. 220
    • Yasuoka, H.1    Kodama, R.2    Tsujimoto, M.3    Yoshidome, K.4    Akamatsu, H.5    Nakahara, M.6
  • 23
    • 18744374621 scopus 로고    scopus 로고
    • VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms
    • PMID:15765121
    • Schoeffner DJ, Matheny SL, Akahane T, Factor V, Berry A, Merlino G, et al. VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms. Lab Invest 2005; 85:608-23; PMID:15765121; http://dx.doi.org/10.1038/labinvest.3700258.
    • (2005) Lab Invest , vol.85 , pp. 608-623
    • Schoeffner, D.J.1    Matheny, S.L.2    Akahane, T.3    Factor, V.4    Berry, A.5    Merlino, G.6
  • 24
    • 0036731988 scopus 로고    scopus 로고
    • Transcriptional regulation of VEGF by estradiol and tamoxifen in breast cancer cells: A complex interplay between estrogen receptors alpha and beta
    • PMID:12208749
    • Buteau-Lozano H, Ancelin M, Lardeux B, Milanini J, Perrot-Applanat M. Transcriptional regulation of VEGF by estradiol and tamoxifen in breast cancer cells: a complex interplay between estrogen receptors alpha and beta. Cancer Res 2002; 62:4977-84; PMID:12208749.
    • (2002) Cancer Res , vol.62 , pp. 4977-4984
    • Buteau-Lozano, H.1    Ancelin, M.2    Lardeux, B.3    Milanini, J.4    Perrot-Applanat, M.5
  • 25
    • 54249121682 scopus 로고    scopus 로고
    • An autocrine VEGF/VEGFR2 and p38 signaling loop confers resistance to 4-hydroxytamoxifen in MCF-7 breast cancer cells
    • PMID:18922978
    • Aesoy R, Sanchez BC, Norum JH, Lewensohn R, Viktorsson K, Linderholm B. An autocrine VEGF/VEGFR2 and p38 signaling loop confers resistance to 4-hydroxytamoxifen in MCF-7 breast cancer cells. Mol Cancer Res 2008; 6:1630-8; PMID:18922978; http://dx.doi.org/10.1158/1541-7786.MCR-07-2172.
    • (2008) Mol Cancer Res , vol.6 , pp. 1630-1638
    • Aesoy, R.1    Sanchez, B.C.2    Norum, J.H.3    Lewensohn, R.4    Viktorsson, K.5    Linderholm, B.6
  • 26
    • 38749097333 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an autocrine survival factor for breast tumour cells under hypoxia
    • PMID:18097541
    • Barr MP, Bouchier-Hayes DJ, Harmey JJ. Vascular endothelial growth factor is an autocrine survival factor for breast tumour cells under hypoxia. Int J Oncol 2008; 32:41-8; PMID:18097541.
    • (2008) Int J Oncol , vol.32 , pp. 41-48
    • Barr, M.P.1    Bouchier-Hayes, D.J.2    Harmey, J.J.3
  • 27
    • 0034929216 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
    • PMID:11461089
    • Pidgeon GP, Barr MP, Harmey JH, Foley DA, Bouchier-Hayes DJ. Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells. Br J Cancer 2001; 85:273-8; PMID:11461089; http://dx.doi.org/10.1054/bjoc.2001.1876.
    • (2001) Br J Cancer , vol.85 , pp. 273-278
    • Pidgeon, G.P.1    Barr, M.P.2    Harmey, J.H.3    Foley, D.A.4    Bouchier-Hayes, D.J.5
  • 28
    • 33747470602 scopus 로고    scopus 로고
    • Nonangiogenic functions of VEGF in breast cancer
    • PMID:16924371
    • Mercurio AM, Lipscomb EA, Bachelder RE. Nonangiogenic functions of VEGF in breast cancer. J Mammary Gland Biol Neoplasia 2005; 10:283-90; PMID:16924371; http://dx.doi.org/10.1007/s10911-006-9001-9.
    • (2005) J Mammary Gland Biol Neoplasia , vol.10 , pp. 283-290
    • Mercurio, A.M.1    Lipscomb, E.A.2    Bachelder, R.E.3
  • 29
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
    • PMID:17550303
    • Lee T-H, Seng S, Sekine M, Hinton C, Fu Y, Avraham HK, et al. Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med 2007; 4:e186; PMID:17550303; http://dx.doi.org/10.1371/journal.pmed.0040186.
    • (2007) PLoS Med , vol.4
    • Lee, T.-H.1    Seng, S.2    Sekine, M.3    Hinton, C.4    Fu, Y.5    Avraham, H.K.6
  • 30
    • 84855179939 scopus 로고    scopus 로고
    • Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions
    • PMID:21897119
    • Vintonenko N, Pelaez-Garavito I, Buteau-Lozano H, Toullec A, Lidereau R, Perret GY, et al. Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions. Cell Adh Migr 2011; 5:332-43; PMID:21897119; http://dx.doi.org/10.4161/cam.5.4.17287.
    • (2011) Cell Adh Migr , vol.5 , pp. 332-343
    • Vintonenko, N.1    Pelaez-Garavito, I.2    Buteau-Lozano, H.3    Toullec, A.4    Lidereau, R.5    Perret, G.Y.6
  • 31
    • 3142720454 scopus 로고    scopus 로고
    • Hypoxia-induced vascular endothelial growth factor transcription and protection from apoptosis are dependent on alpha6beta1 integrin in breast carcinoma cells
    • PMID:15256436
    • Chung J, Yoon S, Datta K, Bachelder RE, Mercurio AM. Hypoxia-induced vascular endothelial growth factor transcription and protection from apoptosis are dependent on alpha6beta1 integrin in breast carcinoma cells. Cancer Res 2004; 64:4711-6; PMID:15256436; http://dx.doi.org/10.1158/0008-5472.CAN-04-0347.
    • (2004) Cancer Res , vol.64 , pp. 4711-4716
    • Chung, J.1    Yoon, S.2    Datta, K.3    Bachelder, R.E.4    Mercurio, A.M.5
  • 32
    • 32944469169 scopus 로고    scopus 로고
    • Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
    • PMID:16452209
    • Park CC, Zhang H, Pallavicini M, Gray JW, Baehner F, Park CJ, et al. Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res 2006; 66:1526-35; PMID:16452209; http://dx.doi.org/10.1158/0008-5472.CAN-05-3071.
    • (2006) Cancer Res , vol.66 , pp. 1526-1535
    • Park, C.C.1    Zhang, H.2    Pallavicini, M.3    Gray, J.W.4    Baehner, F.5    Park, C.J.6
  • 33
    • 0042704757 scopus 로고    scopus 로고
    • Extracellular matrixbound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation
    • PMID:12709411
    • Hutchings H, Ortega N, Plouët J. Extracellular matrixbound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation. FASEB J 2003; 17:1520-2; PMID:12709411.
    • (2003) FASEB J , vol.17 , pp. 1520-1522
    • Hutchings, H.1    Ortega, N.2    Plouët, J.3
  • 34
    • 84858118438 scopus 로고    scopus 로고
    • Neuropilin-2 regulates a6b1 integrin in the formation of focal adhesions and signaling
    • PMID:22302985
    • Goel HL, Pursell B, Standley C, Fogarty K, Mercurio AM. Neuropilin-2 regulates a6b1 integrin in the formation of focal adhesions and signaling. J Cell Sci 2012; 125:497-506; PMID:22302985; http://dx.doi.org/10.1242/jcs.094433.
    • (2012) J Cell Sci , vol.125 , pp. 497-506
    • Goel, H.L.1    Pursell, B.2    Standley, C.3    Fogarty, K.4    Mercurio, A.M.5
  • 35
    • 0141816865 scopus 로고    scopus 로고
    • Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells
    • PMID:14500350
    • Bachelder RE, Lipscomb EA, Lin X, Wendt MA, Chadborn NH, Eickholt BJ, et al. Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. Cancer Res 2003; 63:5230-3; PMID:14500350.
    • (2003) Cancer Res , vol.63 , pp. 5230-5233
    • Bachelder, R.E.1    Lipscomb, E.A.2    Lin, X.3    Wendt, M.A.4    Chadborn, N.H.5    Eickholt, B.J.6
  • 36
    • 0037115522 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4
    • PMID:12499259
    • Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res 2002; 62:7203-6; PMID:12499259.
    • (2002) Cancer Res , vol.62 , pp. 7203-7206
    • Bachelder, R.E.1    Wendt, M.A.2    Mercurio, A.M.3
  • 37
    • 80051704396 scopus 로고    scopus 로고
    • Invading basement membrane matrix is sufficient for MDA-MB-231 breast cancer cells to develop a stable in vivo metastatic phenotype
    • PMID:21858074
    • Abdelkarim M, Vintonenko N, Starzec A, Robles A, Aubert J, Martin ML, et al. Invading basement membrane matrix is sufficient for MDA-MB-231 breast cancer cells to develop a stable in vivo metastatic phenotype. PLoS One 2011; 6:e23334; PMID:21858074; http://dx.doi.org/10.1371/journal.pone.0023334.
    • (2011) PLoS One , vol.6
    • Abdelkarim, M.1    Vintonenko, N.2    Starzec, A.3    Robles, A.4    Aubert, J.5    Martin, M.L.6
  • 38
    • 47349099427 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: Implications for tumor progression
    • PMID:18554584
    • Wanami LS, Chen HY, Peiró S, García de Herreros A, Bachelder RE. Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression. Exp Cell Res 2008; 314:2448-53; PMID:18554584; http://dx.doi.org/10.1016/j.yexcr.2008.05.004.
    • (2008) Exp Cell Res , vol.314 , pp. 2448-2453
    • Wanami, L.S.1    Chen, H.Y.2    Peiró, S.3    García De Herreros, A.4    Bachelder, R.E.5
  • 39
    • 84866265028 scopus 로고    scopus 로고
    • Vascular endothelial growth factor A, secreted in response to transforming growth factor-b1 under hypoxic conditions, induces autocrine effects on migration of prostate cancer cells
    • PMID:22705563
    • Darrington E, Zhong M, Vo BH, Khan SA. Vascular endothelial growth factor A, secreted in response to transforming growth factor-b1 under hypoxic conditions, induces autocrine effects on migration of prostate cancer cells. Asian J Androl 2012; 14:745-51; PMID:22705563; http://dx.doi.org/10.1038/aja. 2011.197.
    • (2012) Asian J Androl , vol.14 , pp. 745-751
    • Darrington, E.1    Zhong, M.2    Vo, B.H.3    Khan, S.A.4
  • 40
    • 84859043508 scopus 로고    scopus 로고
    • Extract of Pleurotus pulmonarius suppresses liver cancer development and progression through inhibition of VEGF-induced PI3K/AKT signaling pathway
    • PMID:22470568
    • Xu W, Huang JJ, Cheung PC. Extract of Pleurotus pulmonarius suppresses liver cancer development and progression through inhibition of VEGF-induced PI3K/AKT signaling pathway. PLoS One 2012; 7:e34406; PMID:22470568; http://dx.doi.org/10.1371/journal.pone.0034406.
    • (2012) PLoS One , vol.7
    • Xu, W.1    Huang, J.J.2    Cheung, P.C.3
  • 41
    • 80055003796 scopus 로고    scopus 로고
    • A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours
    • PMID:22012397
    • Beck B, Driessens G, Goossens S, Youssef KK, Kuchnio A, Caauwe A, et al. A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours. Nature 2011; 478:399-403; PMID:22012397; http://dx.doi.org/10. 1038/nature10525.
    • (2011) Nature , vol.478 , pp. 399-403
    • Beck, B.1    Driessens, G.2    Goossens, S.3    Youssef, K.K.4    Kuchnio, A.5    Caauwe, A.6
  • 42
    • 0036009760 scopus 로고    scopus 로고
    • VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding
    • PMID:11948691
    • Soker S, Miao HQ, Nomi M, Takashima S, Klagsbrun M. VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding. J Cell Biochem 2002; 85:357-68; PMID:11948691; http://dx.doi.org/10.1002/jcb.10140.
    • (2002) J Cell Biochem , vol.85 , pp. 357-368
    • Soker, S.1    Miao, H.Q.2    Nomi, M.3    Takashima, S.4    Klagsbrun, M.5
  • 43
    • 0035816698 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2 and neuropi-lin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121)
    • PMID:11333271
    • Whitaker GB, Limberg BJ, Rosenbaum JS. Vascular endothelial growth factor receptor-2 and neuropi-lin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121). J Biol Chem 2001; 276:25520-31; PMID:11333271; http://dx.doi.org/10.1074/jbc.M102315200.
    • (2001) J Biol Chem , vol.276 , pp. 25520-25531
    • Whitaker, G.B.1    Limberg, B.J.2    Rosenbaum, J.S.3
  • 44
    • 33845991161 scopus 로고    scopus 로고
    • Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
    • PMID:17222790
    • Pan Q, Chanthery Y, Liang WC, Stawicki S, Mak J, Rathore N, et al. Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell 2007; 11:53-67; PMID:17222790; http://dx.doi.org/10. 1016/j.ccr.2006.10.018.
    • (2007) Cancer Cell , vol.11 , pp. 53-67
    • Pan, Q.1    Chanthery, Y.2    Liang, W.C.3    Stawicki, S.4    Mak, J.5    Rathore, N.6
  • 45
    • 33747152506 scopus 로고    scopus 로고
    • Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
    • PMID:16621967
    • Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, et al. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Blood 2006; 108:1243-50; PMID:16621967; http://dx.doi.org/10.1182/blood-2005-11-4447.
    • (2006) Blood , vol.108 , pp. 1243-1250
    • Favier, B.1    Alam, A.2    Barron, P.3    Bonnin, J.4    Laboudie, P.5    Fons, P.6
  • 46
    • 41249088330 scopus 로고    scopus 로고
    • Blocking neuropilin-2 function inhibits tumor cell metastasis
    • PMID:18394556
    • Caunt M, Mak J, Liang WC, Stawicki S, Pan Q, Tong RK, et al. Blocking neuropilin-2 function inhibits tumor cell metastasis. Cancer Cell 2008; 13:331-42; PMID:18394556; http://dx.doi.org/10.1016/j.ccr.2008.01.029.
    • (2008) Cancer Cell , vol.13 , pp. 331-342
    • Caunt, M.1    Mak, J.2    Liang, W.C.3    Stawicki, S.4    Pan, Q.5    Tong, R.K.6
  • 47
    • 33745063095 scopus 로고    scopus 로고
    • The role of neuropilins in cancer
    • PMID:16731741
    • Ellis LM. The role of neuropilins in cancer. Mol Cancer Ther 2006; 5:1099-107; PMID:16731741; http://dx.doi.org/10.1158/1535-7163.MCT-05-0538.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1099-1107
    • Ellis, L.M.1
  • 48
    • 80051990644 scopus 로고    scopus 로고
    • Multifaceted role of neuropilins in cancer
    • PMID:21756227
    • Rizzolio S, Tamagnone L. Multifaceted role of neuropilins in cancer. Curr Med Chem 2011; 18:3563-75; PMID:21756227; http://dx.doi.org/10.2174/ 092986711796642544.
    • (2011) Curr Med Chem , vol.18 , pp. 3563-3575
    • Rizzolio, S.1    Tamagnone, L.2
  • 49
    • 23644434724 scopus 로고    scopus 로고
    • Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells
    • PMID:15956974
    • Wey JS, Gray MJ, Fan F, Belcheva A, McCarty MF, Stoeltzing O, et al. Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells. Br J Cancer 2005; 93:233-41; PMID:15956974; http://dx.doi.org/10.1038/sj.bjc.6602663.
    • (2005) Br J Cancer , vol.93 , pp. 233-241
    • Wey, J.S.1    Gray, M.J.2    Fan, F.3    Belcheva, A.4    McCarty, M.F.5    Stoeltzing, O.6
  • 51
    • 84859488831 scopus 로고    scopus 로고
    • Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1
    • PMID:22318724
    • Parker MW, Xu P, Li X, Vander Kooi CW. Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1. J Biol Chem 2012; 287:11082-9; PMID:22318724; http://dx.doi.org/10.1074/jbc.M111. 331140.
    • (2012) J Biol Chem , vol.287 , pp. 11082-11089
    • Parker, M.W.1    Xu, P.2    Li, X.3    Vander Kooi, C.W.4
  • 52
    • 84869038134 scopus 로고    scopus 로고
    • Mechanism of Selective VEGF-A Binding by Neuropilin-1 Reveals a Basis for Specific Ligand Inhibition
    • PMID:23145112
    • Parker MW, Xu P, Guo HF, Vander Kooi CW. Mechanism of Selective VEGF-A Binding by Neuropilin-1 Reveals a Basis for Specific Ligand Inhibition. PLoS One 2012; 7:e49177; PMID:23145112; http://dx.doi.org/10.1371/journal.pone.0049177.
    • (2012) PLoS One , vol.7
    • Parker, M.W.1    Xu, P.2    Guo, H.F.3    Vander Kooi, C.W.4
  • 53
    • 47949102937 scopus 로고    scopus 로고
    • The semaphorins: Versatile regulators of tumour progression and tumour angiogenesis
    • PMID:18580951
    • Neufeld G, Kessler O. The semaphorins: versatile regulators of tumour progression and tumour angiogenesis. Nat Rev Cancer 2008; 8:632-45; PMID:18580951; http://dx.doi.org/10.1038/nrc2404.
    • (2008) Nat Rev Cancer , vol.8 , pp. 632-645
    • Neufeld, G.1    Kessler, O.2
  • 54
    • 84865137629 scopus 로고    scopus 로고
    • Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer
    • PMID:22897846
    • Tamagnone L. Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer. Cancer Cell 2012; 22:145-52; PMID:22897846; http://dx.doi.org/10.1016/j.ccr.2012.06.031.
    • (2012) Cancer Cell , vol.22 , pp. 145-152
    • Tamagnone, L.1
  • 55
    • 3843113186 scopus 로고    scopus 로고
    • Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect
    • PMID:15273288
    • Castro-Rivera E, Ran S, Thorpe P, Minna JD. Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect. Proc Natl Acad Sci U S A 2004; 101:11432-7; PMID:15273288; http://dx.doi.org/10.1073/pnas.0403969101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11432-11437
    • Castro-Rivera, E.1    Ran, S.2    Thorpe, P.3    Minna, J.D.4
  • 56
    • 0032215144 scopus 로고    scopus 로고
    • Neuropilin-2 is a receptor for semaphorin IV: Insight into the structural basis of receptor function and specificity
    • PMID:9856463
    • Giger RJ, Urquhart ER, Gillespie SK, Levengood DV, Ginty DD, Kolodkin AL. Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity. Neuron 1998; 21:1079-92; PMID:9856463; http://dx.doi.org/10.1016/S0896-6273(00)80625-X.
    • (1998) Neuron , vol.21 , pp. 1079-1092
    • Giger, R.J.1    Urquhart, E.R.2    Gillespie, S.K.3    Levengood, D.V.4    Ginty, D.D.5    Kolodkin, A.L.6
  • 57
    • 0033568863 scopus 로고    scopus 로고
    • A dominant negative receptor for specific secreted semaphorins is generated by deleting an extracellular domain from neuropilin-1
    • PMID:10479689
    • Renzi MJ, Feiner L, Koppel AM, Raper JA. A dominant negative receptor for specific secreted semaphorins is generated by deleting an extracellular domain from neuropilin-1. J Neurosci 1999; 19:7870-80; PMID:10479689.
    • (1999) J Neurosci , vol.19 , pp. 7870-7880
    • Renzi, M.J.1    Feiner, L.2    Koppel, A.M.3    Raper, J.A.4
  • 58
    • 0032408496 scopus 로고    scopus 로고
    • Semaphorin-neuropilin interactions underlying sympathetic axon responses to class III semaphorins
    • PMID:9883722
    • Chen H, He Z, Bagri A, Tessier-Lavigne M. Semaphorin-neuropilin interactions underlying sympathetic axon responses to class III semaphorins. Neuron 1998; 21:1283-90; PMID:9883722; http://dx.doi.org/10.1016/S0896-6273(00) 80648-0.
    • (1998) Neuron , vol.21 , pp. 1283-1290
    • Chen, H.1    He, Z.2    Bagri, A.3    Tessier-Lavigne, M.4
  • 59
    • 0032215735 scopus 로고    scopus 로고
    • Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse
    • PMID:9856464
    • Nakamura F, Tanaka M, Takahashi T, Kalb RG, Strittmatter SM. Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse. Neuron 1998; 21:1093-100; PMID:9856464; http://dx.doi.org/10.1016/S0896-6273(00) 80626-1.
    • (1998) Neuron , vol.21 , pp. 1093-1100
    • Nakamura, F.1    Tanaka, M.2    Takahashi, T.3    Kalb, R.G.4    Strittmatter, S.M.5
  • 60
    • 34548500340 scopus 로고    scopus 로고
    • Site-directed mutagenesis in the B-neuropilin-2 domain selectively enhances its affinity to VEGF165, but not to semaphorin 3F
    • PMID:17595163
    • Geretti E, Shimizu A, Kurschat P, Klagsbrun M. Site-directed mutagenesis in the B-neuropilin-2 domain selectively enhances its affinity to VEGF165, but not to semaphorin 3F. J Biol Chem 2007; 282:25698-707; PMID:17595163; http://dx.doi.org/10.1074/jbc.M702942200.
    • (2007) J Biol Chem , vol.282 , pp. 25698-25707
    • Geretti, E.1    Shimizu, A.2    Kurschat, P.3    Klagsbrun, M.4
  • 61
    • 0033549556 scopus 로고    scopus 로고
    • Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: Functional competition of collapsin-1 and vascular endothelial growth factor-165
    • PMID:10402473
    • Miao HQ, Soker S, Feiner L, Alonso JL, Raper JA, Klagsbrun M. Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165. J Cell Biol 1999; 146:233-42; PMID:10402473.
    • (1999) J Cell Biol , vol.146 , pp. 233-242
    • Miao, H.Q.1    Soker, S.2    Feiner, L.3    Alonso, J.L.4    Raper, J.A.5    Klagsbrun, M.6
  • 62
    • 0030722135 scopus 로고    scopus 로고
    • The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing
    • PMID:9321387
    • Adams RH, Lohrum M, Klostermann A, Betz H, Püschel AW. The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing. EMBO J 1997; 16:6077-86; PMID:9321387; http://dx.doi.org/10.1093/emboj/16.20.6077.
    • (1997) EMBO J , vol.16 , pp. 6077-6086
    • Adams, R.H.1    Lohrum, M.2    Klostermann, A.3    Betz, H.4    Püschel, A.W.5
  • 63
    • 77952341533 scopus 로고    scopus 로고
    • Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin
    • PMID:20387901
    • Parker MW, Hellman LM, Xu P, Fried MG, Vander Kooi CW. Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin. Biochemistry 2010; 49:4068-75; PMID:20387901; http://dx.doi.org/10.1021/bi100327r.
    • (2010) Biochemistry , vol.49 , pp. 4068-4075
    • Parker, M.W.1    Hellman, L.M.2    Xu, P.3    Fried, M.G.4    Vander Kooi, C.W.5
  • 64
    • 0034688995 scopus 로고    scopus 로고
    • Determination of cell adhesion sites of neuropilin-1
    • PMID:10725340
    • Shimizu M, Murakami Y, Suto F, Fujisawa H. Determination of cell adhesion sites of neuropilin-1. J Cell Biol 2000; 148:1283-93; PMID:10725340; http://dx.doi.org/10.1083/jcb.148.6.1283.
    • (2000) J Cell Biol , vol.148 , pp. 1283-1293
    • Shimizu, M.1    Murakami, Y.2    Suto, F.3    Fujisawa, H.4
  • 65
    • 79953702245 scopus 로고    scopus 로고
    • Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta
    • PMID:21186301
    • Glinka Y, Stoilova S, Mohammed N, Prud'homme GJ. Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta. Carcinogenesis 2011; 32:613-21; PMID:21186301; http://dx.doi.org/10.1093/carcin/bgq281.
    • (2011) Carcinogenesis , vol.32 , pp. 613-621
    • Glinka, Y.1    Stoilova, S.2    Mohammed, N.3    Prud'Homme, G.J.4
  • 66
    • 0033179591 scopus 로고    scopus 로고
    • Cloning and characterization of neuropilin-1-interacting protein: A PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1
    • PMID:10414980
    • Cai H, Reed RR. Cloning and characterization of neuropilin-1-interacting protein: a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1. J Neurosci 1999; 19:6519-27; PMID:10414980.
    • (1999) J Neurosci , vol.19 , pp. 6519-6527
    • Cai, H.1    Reed, R.R.2
  • 67
    • 0033869852 scopus 로고    scopus 로고
    • Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration
    • PMID:10911369
    • Gao Y, Li M, Chen W, Simons M. Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration. J Cell Physiol 2000; 184:373-9; PMID:10911369; http://dx.doi.org/10.1002/1097-4652(200009)184:3〈373::AID- JCP12〉3.0.CO;2-I.
    • (2000) J Cell Physiol , vol.184 , pp. 373-379
    • Gao, Y.1    Li, M.2    Chen, W.3    Simons, M.4
  • 68
    • 33845678052 scopus 로고    scopus 로고
    • C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis
    • PMID:16754745
    • Wang L, Mukhopadhyay D, Xu X. C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB J 2006; 20:1513-5; PMID:16754745; http://dx.doi.org/10.1096/fj.05-5504fje.
    • (2006) FASEB J , vol.20 , pp. 1513-1515
    • Wang, L.1    Mukhopadhyay, D.2    Xu, X.3
  • 69
    • 54449093538 scopus 로고    scopus 로고
    • Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1
    • PMID:18628209
    • Prahst C, Héroult M, Lanahan AA, Uziel N, Kessler O, Shraga-Heled N, et al. Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1. J Biol Chem 2008; 283:25110-4; PMID:18628209; http://dx.doi.org/ 10.1074/jbc.C800137200.
    • (2008) J Biol Chem , vol.283 , pp. 25110-25114
    • Prahst, C.1    Héroult, M.2    Lanahan, A.A.3    Uziel, N.4    Kessler, O.5    Shraga-Heled, N.6
  • 70
    • 58849090461 scopus 로고    scopus 로고
    • Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells
    • PMID:19175293
    • Valdembri D, Caswell PT, Anderson KI, Schwarz JP, König I, Astanina E, et al. Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol 2009; 7:e25; PMID:19175293; http://dx.doi.org/10.1371/journal.pbio.1000025.
    • (2009) PLoS Biol , vol.7
    • Valdembri, D.1    Caswell, P.T.2    Anderson, K.I.3    Schwarz, J.P.4    König, I.5    Astanina, E.6
  • 71
    • 78650495520 scopus 로고    scopus 로고
    • RGS-GAIP-interacting protein controls breast cancer progression
    • PMID:21047775
    • Wang L, Lau JS, Patra CR, Cao Y, Bhattacharya S, Dutta S, et al. RGS-GAIP-interacting protein controls breast cancer progression. Mol Cancer Res 2010; 8:1591-600; PMID:21047775; http://dx.doi.org/10.1158/1541-7786.MCR-10- 0209.
    • (2010) Mol Cancer Res , vol.8 , pp. 1591-1600
    • Wang, L.1    Lau, J.S.2    Patra, C.R.3    Cao, Y.4    Bhattacharya, S.5    Dutta, S.6
  • 72
    • 79953244361 scopus 로고    scopus 로고
    • Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
    • PMID:21364524
    • Ebos JM, Kerbel RS. Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat Rev Clin Oncol 2011; 8:210-21; PMID:21364524; http://dx.doi.org/10.1038/nrclinonc.2011.21.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 210-221
    • Ebos, J.M.1    Kerbel, R.S.2
  • 73
    • 54549123309 scopus 로고    scopus 로고
    • VEGF-A splicing: The key to anti-angiogenic therapeutics?
    • PMID:18923433
    • Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat Rev Cancer 2008; 8:880-7; PMID:18923433; http://dx.doi.org/10. 1038/nrc2505.
    • (2008) Nat Rev Cancer , vol.8 , pp. 880-887
    • Harper, S.J.1    Bates, D.O.2
  • 74
    • 84862682219 scopus 로고    scopus 로고
    • VEGF spliced variants: Possible role of anti-angiogenesis therapy
    • PMID:22013509
    • Hilmi C, Guyot M, Pagès G. VEGF spliced variants: possible role of anti-angiogenesis therapy. J Nucleic Acids 2012; 2012:162692-8; PMID:22013509; http://dx.doi.org/10.1155/2012/162692.
    • (2012) J Nucleic Acids , vol.2012 , pp. 162692-162698
    • Hilmi, C.1    Guyot, M.2    Pagès, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.