Homocysteine triggers inflammatory responses in macrophages through inhibiting CSE-H2S signaling via DNA hypermethylation of CSE promoter

International Journal of Molecular Sciences

Volumn 16, Issue 6, 2015, Pages 12560-12577

  Li, Jiao Jiao ^a   Li, Qian ^b   Du, Hua Ping ^a   Wang, Ya Li ^a,b   You, Shou Jiang ^a   Wang, Fen ^a,b   Xu, Xing Shun ^a   Cheng, Jian ^b   Cao, Yong Jun ^a   Liu, Chun Feng ^a,b   Hu, Li Fang ^a,b  

^a THE SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

Cystathionine lyase; DNA Methylation; Homocysteine; Hydrogen sulfide; Macrophage

Indexed keywords

BISULFITE; CYSTATHIONINE GAMMA LYASE; HOMOCYSTEINE; HYDROGEN SULFIDE; INTERLEUKIN 1BETA; MESSENGER RNA; S ADENOSYLMETHIONINE; TETRAHYDROFOLIC ACID; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; DNA (CYTOSINE 5) METHYLTRANSFERASE; GYY 4137; METHIONINE; MORPHOLINE DERIVATIVE; PHOSPHOROTHIOIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; INFLAMMATION; MACROPHAGE MIGRATION INHIBITION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HYPERHOMOCYSTEINEMIA; IMMUNOLOGY; MACROPHAGE; METABOLISM; PROMOTER REGION;

MUS;

ANIMALS; CELLS, CULTURED; CYSTATHIONINE GAMMA-LYASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GENE EXPRESSION REGULATION; HOMOCYSTEINE; HYDROGEN SULFIDE; HYPERHOMOCYSTEINEMIA; INFLAMMATION MEDIATORS; MACROPHAGES; MALE; METHIONINE; MICE; MORPHOLINES; ORGANOTHIOPHOSPHORUS COMPOUNDS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 84931291912     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160612560     Document Type: Article

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