Using strictosidine synthase to prepare novel alkaloids

Current Medicinal Chemistry

Volumn 22, Issue 15, 2015, Pages 1880-1888

  Zhu, Huajian ^a   Kerɥmar, Petra ^b   Wu, Fangrui ^a,c   Rajendran, Chitra ^d   Sun, Lianli ^a   Wang, Meitian ^e   Stöckigt, Joachim ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b Sandoz Company Biopharmaceuticals   (Slovenia)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF REGENSBURG   (Germany)

^e PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

Alkaloids; Application strategies; Protein engineering; Strictosidine synthase; Substrates; X ray complex structures

Indexed keywords

ALKALOID DERIVATIVE; STRICTOSIDINE; STRICTOSIDINE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CATHARANTHUS ROSEUS; CHEMICAL STRUCTURE; ENZYME SUBSTRATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PROTEIN ENGINEERING; RAUWOLFIA; REACTION ANALYSIS; X RAY ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 84931287736     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867322666150408110919     Document Type: Article

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