-
1
-
-
7144248725
-
Plant anti-tumor agents I. the isolation and structure of camptothecin-a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata
-
ME Wall MC Wani CE Cook KH Palmer 1966 Plant anti-tumor agents I. The isolation and structure of camptothecin-a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata J Am Chem Soc 88 3888 3890
-
(1966)
J Am Chem Soc
, vol.88
, pp. 3888-3890
-
-
Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
Palmer, K.H.4
-
2
-
-
4944264246
-
Camptothecin, over four decades of surprising findings
-
DOI 10.1016/j.phytochem.2004.09.001, PII S0031942204004686
-
L Lorence CL Nessler 2004 Camptothecin, over four decades of surprising findings Phytochemistry 65 2735 2749 10.1016/j.phytochem.2004.09.001 (Pubitemid 39330172)
-
(2004)
Phytochemistry
, vol.65
, Issue.20
, pp. 2735-2749
-
-
Lorence, A.1
Nessler, C.L.2
-
3
-
-
0018572014
-
Plant anticancer agents X. Isolation of camptothecin and 9-methoxycamptothecin from Ervatamia heyneana
-
DOI 10.1021/np50005a006
-
SP Gunasekera MM Badawi GA Cordell NR Farnsworth M Chitnis 1979 Plant anticancer agents X. Isolation of camptothecin and 9-methoxycamptothecin from Ervatamia heyneana J Nat Prod 42 475 477 10.1021/np50005a006 (Pubitemid 10185386)
-
(1979)
Journal of Natural Products
, vol.42
, Issue.5
, pp. 475-477
-
-
Gunasekera, S.P.1
Badawi, M.M.2
Cordeli, G.A.3
-
4
-
-
0019838879
-
Plant anticancer agents XXI Constituents of Merrilliodendron megacarpum
-
10.1055/s-2007-971533
-
M Arisawa SP Gunasekera GA Cordell NR Farnsworth 1981 Plant anticancer agents XXI Constituents of Merrilliodendron megacarpum Planta Med 43 404 407 10.1055/s-2007-971533
-
(1981)
Planta Med
, vol.43
, pp. 404-407
-
-
Arisawa, M.1
Gunasekera, S.P.2
Cordell, G.A.3
Farnsworth, N.R.4
-
6
-
-
0017137483
-
Antiviral components of Ophiorrhiza mungos. Isolation of camptothecin and 10-methoxycamptothecin
-
S Tafur JD Nelson DC De Long GH Svoboda 1976 Antiviral components of Ophiorrhiza mungos. Isolation of camptothecin and 10-methoxycamptothecin Lloydia 39 261 262
-
(1976)
Lloydia
, vol.39
, pp. 261-262
-
-
Tafur, S.1
Nelson, J.D.2
De Long, D.C.3
Svoboda, G.H.4
-
8
-
-
0021891888
-
DNA topoisomerases
-
10.1146/annurev.bi.54.070185.003313
-
JC Wang 1985 DNA topoisomerases Annu Rev Biochem 54 665 697 10.1146/annurev.bi.54.070185.003313
-
(1985)
Annu Rev Biochem
, vol.54
, pp. 665-697
-
-
Wang, J.C.1
-
9
-
-
0027092752
-
Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I
-
DOI 10.1016/0022-2836(92)90310-G
-
E Kjeldsen JQ Svejstrup II Gromova J Alsner O Westergaard 1992 Camptothecin inhibits both the cleavage and relegation reactions of eukaryotic DNA topoisomerase I J Mol Biol 28 1025 1030 10.1016/0022-2836(92)90310-G (Pubitemid 23018485)
-
(1992)
Journal of Molecular Biology
, vol.228
, Issue.4
, pp. 1025-1030
-
-
Kjeldsen, E.1
Svejstrup, J.Q.2
Gromova, I.I.3
Alsner, J.4
Westergaard, O.5
-
10
-
-
1442334562
-
Camptothecin and Taxol: Historic Achievements in Natural Products Research
-
DOI 10.1021/np030498t
-
NH Oberlies DJ Kroll 2004 Camptothecin and taxol: historic achievements in natural products research J Nat Prod 67 129 135 10.1021/np030498t (Pubitemid 38282896)
-
(2004)
Journal of Natural Products
, vol.67
, Issue.2
, pp. 129-135
-
-
Oberlies, N.H.1
Kroll, D.J.2
-
11
-
-
0030826929
-
Topoisomerase I inhibitors: Review and update
-
DOI 10.1023/A:1008270717294
-
ML Rothenberg 1997 Topoisomerase I inhibitors: review and update Ann Oncol 8 837 855 10.1023/A:1008270717294 (Pubitemid 27452081)
-
(1997)
Annals of Oncology
, vol.8
, Issue.9
, pp. 837-855
-
-
Rothenberg, M.L.1
-
12
-
-
0031682217
-
Camptothecin and taxol: Discovery to clinic
-
10.1002/(SICI)1098-1128(199809)18:5<299:AID-MED2>3.0.CO;2-O
-
ME Wall 1998 Camptothecin and taxol: discovery to clinic Med Res Rev 18 299 314 10.1002/(SICI)1098-1128(199809)18:5<299:AID-MED2>3.0.CO;2-O
-
(1998)
Med Res Rev
, vol.18
, pp. 299-314
-
-
Wall, M.E.1
-
13
-
-
0026082794
-
Inhibition of human immunodeficiency virus (HIV-1) replication in vitro by non-cytotoxic doses of camptothecin, a topoisomerase i inhibitor
-
E Priel SD Showalter DG Blair 1991 Inhibition of human immunodeficiency virus (HIV-1) replication in vitro by non-cytotoxic doses of camptothecin, a topoisomerase I inhibitor AIDS Res Hum Retroviruses 7 65 72
-
(1991)
AIDS Res Hum Retroviruses
, vol.7
, pp. 65-72
-
-
Priel, E.1
Showalter, S.D.2
Blair, D.G.3
-
15
-
-
4944264246
-
Camptothecin, over four decades of surprising findings
-
DOI 10.1016/j.phytochem.2004.09.001, PII S0031942204004686
-
L Lorence CL Nessler 2004 Camptothecin, over four decades of surprising findings Phytochemistry 65 2735 2749 10.1016/j.phytochem.2004.09.001 (Pubitemid 39330172)
-
(2004)
Phytochemistry
, vol.65
, Issue.20
, pp. 2735-2749
-
-
Lorence, A.1
Nessler, C.L.2
-
16
-
-
12244300614
-
Metabolic engineering of plant secondary metabolism: A promising approach to the production of pharmaceuticals
-
K Springob K Saito 2002 Metabolic engineering of plant secondary metabolism: a promising approach to the production of pharmaceuticals Sci Cult 68 76 85
-
(2002)
Sci Cult
, vol.68
, pp. 76-85
-
-
Springob, K.1
Saito, K.2
-
17
-
-
0001153463
-
Biosynthesis of camptothecin. 3. Definition of strictosamide as the penultimate biosynthetic precursor assisted by 13C and 2H NMR spectroscopy
-
10.1021/ja00506a037
-
CR Hutchinson AH Heckendorf JL Straughn PE Daddona DE Cane 1979) Biosynthesis of camptothecin. 3. Definition of strictosamide as the penultimate biosynthetic precursor assisted by 13C and 2H NMR spectroscopy J Am Chem Soc 101 3358 3369 10.1021/ja00506a037
-
(1979)
J Am Chem Soc
, vol.101
, pp. 3358-3369
-
-
Hutchinson, C.R.1
Heckendorf, A.H.2
Straughn, J.L.3
Daddona, P.E.4
Cane, D.E.5
-
18
-
-
0028083884
-
Heterologous expression of the plant proteins strictosidine synthase and berberine bridge enzyme in insect cell culture
-
DOI 10.1016/S0031-9422(00)94763-0
-
TM Kutchan A Bock H Dittrich 1994 Heterologous expression of the plant proteins strictosidine synthase and berberine bridge enzyme in insect cell culture Phytochemistry 35 353 360 10.1016/S0031-9422(00)94763-0 (Pubitemid 2036579)
-
(1994)
Phytochemistry
, vol.35
, Issue.2
, pp. 353-360
-
-
Kutchan, T.M.1
Bock, A.2
Dittrich, H.3
-
19
-
-
0024977242
-
Expression of enzymatically active cloned strictosidine synthase from the higher plant Rauvolfia serpentina in Escherichia coli
-
10.1016/0014-5793(89)81802-2
-
TM Kutchan 1989 Expression of enzymatically active cloned strictosidine synthase from the higher plant Rauvolfia serpentina in Escherichia coli FEBS Lett 257 127 130 10.1016/0014-5793(89)81802-2
-
(1989)
FEBS Lett
, vol.257
, pp. 127-130
-
-
Kutchan, T.M.1
-
20
-
-
0025044913
-
Nucleotide sequence of a cDNA encoding the vacuolar protein strictosidine synthase from Catharanthus roseus
-
10.1093/nar/18.16.4939
-
TD McKnight CA Roessner R Devagupta AI Scott CL Nessler 1990 Nucleotide sequence of a cDNA encoding the vacuolar protein strictosidine synthase from Catharanthus roseus Nucleic Acids Res 18 4939 10.1093/nar/18.16.4939
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 4939
-
-
McKnight D, T.1
Roessner, C.A.2
Devagupta, R.3
Scott, A.I.4
Nessler, C.L.5
-
21
-
-
0032127941
-
Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus
-
DOI 10.1007/s004250050338
-
C Canel MI Lopes-Cardoso S Whitmer 1998 Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus Planta 205 414 419 10.1007/s004250050338 (Pubitemid 28324165)
-
(1998)
Planta
, vol.205
, Issue.3
, pp. 414-419
-
-
Canel, C.1
Lopes-Cardoso, M.I.2
Whitmer, S.3
Van Der Fits, L.4
Pasquali, G.5
Van Der Heijden, R.6
Hoge, J.H.C.7
Verpoorte, R.8
-
23
-
-
85001054586
-
The research of camptothecin content in two Ophiorrhiza in XiangXi
-
BL Yi QZ Peng XR Tian 2007 The research of camptothecin content in two Ophiorrhiza in XiangXi J Changsha Univ 21 5 35 36
-
(2007)
J Changsha Univ
, vol.21
, Issue.5
, pp. 35-36
-
-
Yi, B.L.1
Peng, Q.Z.2
Tian, X.R.3
-
24
-
-
33745454786
-
Molecular cloning and expression analyses of a new gene encoding 3-hydroxy-3- methylglutaryl-CoA synthase from Taxus x media
-
10.1007/s10535-006-0050-0
-
GY Kai ZQ Miao L Zhang DL Zhao ZH Liao XF Sun 2006 Molecular cloning and expression analyses of a new gene encoding 3-hydroxy-3- methylglutaryl-CoA synthase from Taxus x media Biol Plant 50 359 366 10.1007/s10535-006-0050-0
-
(2006)
Biol Plant
, vol.50
, pp. 359-366
-
-
Kai, G.Y.1
Miao, Z.Q.2
Zhang, L.3
Zhao, D.L.4
Liao, Z.H.5
Sun, X.F.6
-
25
-
-
32644437468
-
Characterization and expression profile analysis of a new cDNA encoding taxadiene synthase from Taxus media
-
GY Kai LX Zhao L Zhang ZG Li BH Guo DL Zhao 2005 Characterization and expression profile analysis of a new cDNA encoding taxadiene synthase from Taxus media J Biochem Mol Biol 38 675 685
-
(2005)
J Biochem Mol Biol
, vol.38
, pp. 675-685
-
-
Kai, G.Y.1
Zhao, L.X.2
Zhang, L.3
Li, Z.G.4
Guo, B.H.5
Zhao, D.L.6
-
26
-
-
0031574072
-
The CLUSTAL X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
DOI 10.1093/nar/25.24.4876
-
JD Thompson TJ Gibson F Plewniak F Jeanmougin DG Higgins 1997 The CLUSTAL X windows interface:flexible strategies for multiple sequence alignment aided by quality analysis tools Nucleic Acids Res 25 4876 4882 10.1093/nar/25.24.4876 (Pubitemid 28022245)
-
(1997)
Nucleic Acids Research
, vol.25
, Issue.24
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
27
-
-
0036139211
-
MEGA2: Molecular evolutionary genetics analysis software
-
10.1093/bioinformatics/17.12.1244
-
S Kumar K Tamura IB Jakobsen M Nei 2001 MEGA2: molecular evolutionary genetics analysis software Bioinformatics 12 1244 1245 10.1093/bioinformatics/ 17.12.1244
-
(2001)
Bioinformatics
, vol.12
, pp. 1244-1245
-
-
Kumar, S.1
Tamura, K.2
Jakobsen, I.B.3
Nei, M.4
-
28
-
-
0037657891
-
Camptothecin biosynthetic genes in hairy roots of Ophiorrhiza pumila: Cloning, characterization and differential expression in tissues and by stress compounds
-
DOI 10.1093/pcp/pcg051
-
Y Yamazaki H Sudo M Yamazaki N Aimi K Saito 2003 Camptothecin biosynthetic genes in hairy roots of Ophiorrhiza pumila: cloning, characterization and differential expression in tissues and by stress compounds Plant Cell Physiol 44 4 395 403 10.1093/pcp/pcg051 (Pubitemid 36557685)
-
(2003)
Plant and Cell Physiology
, vol.44
, Issue.4
, pp. 395-403
-
-
Yamazaki, Y.1
Sudo, H.2
Yamazaki, M.3
Aimi, N.4
Saito, K.5
-
29
-
-
0026841089
-
Coordinated regulation of two indole alkaloid biosynthetic genes from Catharanthus roseus by auxin and elicitors
-
10.1007/BF00047715
-
G Pasquali OJ Goddijn A de Waal R Verpoorte RA Schilperoort JH Hoge 1992 Coordinated regulation of two indole alkaloid biosynthetic genes from Catharanthus roseus by auxin and elicitors Plant Mol Biol 18 6 1121 1131 10.1007/BF00047715
-
(1992)
Plant Mol Biol
, vol.18
, Issue.6
, pp. 1121-1131
-
-
Pasquali, G.1
Goddijn, O.J.2
De Waal, A.3
Verpoorte, R.4
Schilperoort, R.A.5
Hoge, J.H.6
-
30
-
-
36348965992
-
Molecular cloning and characterization of a new cDNA encoding strictosidine synthase from Rauvolfia verticillata
-
H Wang R Shen M Chen M Sun ZH Liao 2006 Molecular cloning and characterization of a new cDNA encoding strictosidine synthase from Rauvolfia verticillata Acta Bo Boreal-Ocident Sin 26 5 900 905
-
(2006)
Acta Bo Boreal-Ocident Sin
, vol.26
, Issue.5
, pp. 900-905
-
-
Wang, H.1
Shen, R.2
Chen, M.3
Sun, M.4
Liao, Z.H.5
-
31
-
-
0029595442
-
SOPMA: Significant improvement in protein secondary structure prediction by consensus prediction from multiple alignments
-
C Geourjon G Deléage 1995 SOPMA: significant improvement in protein secondary structure prediction by consensus prediction from multiple alignments Cabios 11 681 684
-
(1995)
Cabios
, vol.11
, pp. 681-684
-
-
Geourjon, C.1
Deléage, G.2
-
32
-
-
33745473834
-
The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed β-propeller fold in plant proteins
-
DOI 10.1105/tpc.105.038018
-
X Ma S Panjikar J Koepke E Lorisand J Stöckigt 2006 The Structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed b-propeller fold in plant proteins Plant Cell 18 907 920 10.1105/tpc.105.038018 (Pubitemid 43956144)
-
(2006)
Plant Cell
, vol.18
, Issue.4
, pp. 907-920
-
-
Ma, X.1
Panjikar, S.2
Koepke, J.3
Loris, E.4
Stockigt, J.5
-
33
-
-
33645550377
-
Isolation and expression profile analysis of a new cDNA encoding 5-alpha-taxadienol-10-beta-hydroxylase from Taxus media
-
GY Kai JH Jiang DL Zhao LX Zhao L Zhang ZG Li 2006 Isolation and expression profile analysis of a new cDNA encoding 5-alpha-taxadienol-10-beta- hydroxylase from Taxus media J Plant Biochem Biotechnol 15 1 5
-
(2006)
J Plant Biochem Biotechnol
, vol.15
, pp. 1-5
-
-
Kai, G.Y.1
Jiang, J.H.2
Zhao, D.L.3
Zhao, L.X.4
Zhang, L.5
Li, Z.G.6
-
34
-
-
0025824979
-
Mechanism of inhibitionof cell proliferation by vinca alkaloids
-
MA Jordan D Thrower L Wilsen 1991 Mechanism of inhibitionof cell proliferation by vinca alkaloids Cancer Res 51 2212 2222
-
(1991)
Cancer Res
, vol.51
, pp. 2212-2222
-
-
Jordan, M.A.1
Thrower, D.2
Wilsen, L.3
-
35
-
-
0037309409
-
Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants
-
DOI 10.1016/S0031-9422(02)00543-5, PII S0031942202005435
-
Y Yamazaki A Urano H Sudo M Kitajima H Takayama M Yamazaki 2003 Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants Phytochemistry 62 461 470 10.1016/S0031-9422(02) 00543-5 (Pubitemid 36168948)
-
(2003)
Phytochemistry
, vol.62
, Issue.3
, pp. 461-470
-
-
Yamazaki, Y.1
Urano, A.2
Sudo, H.3
Kitajima, M.4
Takayama, H.5
Yamazaki, M.6
Aimi, N.7
Saito, K.8
-
36
-
-
0035039494
-
Catharanthus roseus G-box binding factors 1 and 2 act as repressors of strictosidine synthase gene expression in cell cultures
-
DOI 10.1023/A:1010650906695
-
Y Sibéril S Benhamron J Memelink N Giglioli-Guivarc'h M Thiersault B Boissoni P Doireau P Gantet 2001 Catharanthus roseus G-box binding factors 1 and 2 act as repressors of strictosidine synthase gene expression in cell cultures Plant Mol Biol 45 477 488 10.1023/A:1010650906695 (Pubitemid 32382760)
-
(2001)
Plant Molecular Biology
, vol.45
, Issue.4
, pp. 477-488
-
-
Siberil, Y.1
Benhamron, S.2
Memelink, J.3
Giglioli-Guivarc'h, N.4
Thiersault, M.5
Boisson, B.6
Doireau, P.7
Gantet, P.8
-
37
-
-
0033575710
-
A novel jasmonate- and elicitor-responsive element in the periwinkle secondary metabolite biosynthetic gene Str interacts with a jasmonate- and elicitor-inducible AP2-domain transcription factor, ORCA2
-
DOI 10.1093/emboj/18.16.4455
-
FLH Menke A Champion JW Kijne J Memelink 1999 A novel jasmonate- and elicitor-responsive element in the periwinkle secondary metabolite biosynthetic gene Str interacts with a jasmonate- and elicitor- inducible AP2-domain ranscription factor, ORCA2 EMBO J 18 4455 4463 10.1093/emboj/18.16.4455 (Pubitemid 29391255)
-
(1999)
EMBO Journal
, vol.18
, Issue.16
, pp. 4455-4463
-
-
Menke, F.L.H.1
Champion, A.2
Kijne, J.W.3
Memelink, J.4
|